Stabilization of proteins in dry powder formulations using supercritical fluid technology

Lyophilization and development of solid protein pharmaceuticals

Wang, W. (2000) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(00)00423-3 · Cited by 1,178 · see citing works

Particle design using supercritical fluids: Literature and patent survey

Jung, J., & Perrut, M. (2001) · The Journal of Supercritical Fluids · doi:10.1016/s0896-8446(01)00064-x · Cited by 1,140 · see citing works

Stability of Protein Pharmaceuticals

Manning, M. C., Patel, K., & Borchardt, R. T. (1989) · Pharmaceutical Research · doi:10.1023/a:1015929109894 · Cited by 1,082 · see citing works

Protein Instability in Poly(Lactic-co-Glycolic Acid) Microparticles

van de Weert, M., Hennink, W. E., & Jiskoot, W. (2000) · Pharmaceutical Research · doi:10.1023/a:1026498209874 · Cited by 707 · see citing works

Rational Design of Stable Lyophilized Protein Formulations: Some Practical Advice

Carpenter, J. F., Pikal, M. J., Chang, B. S., & Randolph, T. W. (1997) · Pharmaceutical Research · doi:10.1023/a:1012180707283 · Cited by 685 · see citing works

Supercritical antisolvent precipitation of micro- and nano-particles

Reverchon, E. (1999) · The Journal of Supercritical Fluids · doi:10.1016/s0896-8446(98)00129-6 · Cited by 615 · see citing works

Natural Extracts Using Supercritical Carbon Dioxide

Mukhopadhyay, M. (2000) · CRC Press eBooks · doi:10.1201/9781420041699 · Cited by 501 · see citing works

Freeze-drying of bioproducts: putting principles into practice

Franks, F. (1998) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(98)00004-6 · Cited by 461 · see citing works

pH-Defining Equilibrium between Water and Supercritical CO2. Influence on SFE of Organics and Metal Chelates

Toews, K. L., Shroll, R. M., Wai, C. M., & Smart, N. G. (1995) · Analytical Chemistry · doi:10.1021/ac00118a002 · Cited by 408 · see citing works

Bacterial inactivation by using near- and supercritical carbon dioxide

Dillow, A. K., Dehghani, F., Hrkach, J. S., Foster, N. R., & Langer, R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10344 · Cited by 323 · see citing works

Structure and thermal/mechanical properties of poly (?-caprolactone)-clay blend

Jiménez, G., Ogata, N., Kawai, H., & Ogihara, T. (1997) · Journal of Applied Polymer Science · doi:10.1002/(sici)1097-4628(19970613)64:11 · Cited by 314 · see citing works

Polymeric materials formed by precipitation with a compressed fluid antisolvent

Dixon, D. J., Johnston, K. P., & Bodmeier, R. A. (1993) · AIChE Journal · doi:10.1002/aic.690390113 · Cited by 311 · see citing works

Formation of microparticulate protein powder using a supercritical fluid antisolvent

Yeo, S., Lim, G., Debenedetti, P. G., et al. (1993) · Biotechnology and Bioengineering · doi:10.1002/bit.260410308 · Cited by 305 · see citing works

Beware of proteins in DMSO

Jackson, M., & Mantsch, H. H. (1991) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(91)90563-f · Cited by 264 · see citing works

Gas Antisolvent Recrystallization: New Process To Recrystallize Compounds Insoluble in Supercritical Fluids

Gallagher, P. M., Coffey, M. P., Krukonis, V. J., et al. (1989) · ACS symposium series · doi:10.1021/bk-1989-0406.ch022 · Cited by 231 · see citing works

Supercritical Fluid Technology for Drug Product Development

York, Y. (2004) · CRC Press eBooks · doi:10.1201/9780203021378 · Cited by 202 · see citing works

Precipitation of Proteins in Supercritical Carbon Dioxide

Winters, M. A., Knutson, B. L., Debenedetti, P. G., Sparks, H. G., Przybycien, T. M., Stevenson, C. L., & Prestrelski, S. J. (1996) · Journal of Pharmaceutical Sciences · doi:10.1021/js950482q · Cited by 200 · see citing works

The Effect of Formulation Excipients on Protein Stability and Aerosol Performance of Spray-Dried Powders of a Recombinant Humanized Anti-IgE Monoclonal Antibody1

Andya, J. D., Maa, Y., Costantino, H. R., Nguyen, P., Dasovich, N., Sweeney, T. D., Hsu, C. C., & Shire, S. J. (1999) · Pharmaceutical Research · doi:10.1023/a:1018805232453 · Cited by 190 · see citing works

Production of Insulin‐Loaded Poly(Ethylene Glycol)/Poly(l‐Lactide) (PEG/PLA) Nanoparticles by Gas Antisolvent Techniques

Elvassore, N., Bertucco, A., & Caliceti, P. (2001) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.1113 · Cited by 155 · see citing works

Phase Behavioral Effects on Particle Formation Processes Using Supercritical Fluids

Palakodaty, S., & York, P. (1999) · Pharmaceutical Research · doi:10.1023/a:1011957512347 · Cited by 144 · see citing works

Rational Design of Stable Protein Formulations

(2002) · Pharmaceutical biotechnology · doi:10.1007/978-1-4615-0557-0 · Cited by 122 · see citing works

Rational design of stable protein formulations : theory and practice

Carpenter, J. F., & Manning, M. C. (2002) · Cited by 118 · see citing works

Phase equilibria for CO2-C2H5OH-H2O system.

Takishima, S., Saiki, K., Arai, K., et al. (1986) · JOURNAL OF CHEMICAL ENGINEERING OF JAPAN · doi:10.1252/jcej.19.48 · Cited by 115 · see citing works

Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO2‐assisted aerosolization

Sellers, S. P., Clark, G. S., Sievers, R. E., et al. (2001) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.1032 · Cited by 115 · see citing works

Current issues relating to anti-solvent micronisation techniques and their extension to industrial scales

Thiering, R., Dehghani, F., & Foster, N. R. (2001) · The Journal of Supercritical Fluids · doi:10.1016/s0896-8446(01)00090-0 · Cited by 112 · see citing works

Protein nanoparticles formation by supercritical antisolvent with enhanced mass transfer

Chattopadhyay, P., & Gupta, R. B. (2002) · AIChE Journal · doi:10.1002/aic.690480207 · Cited by 109 · see citing works

Production of Antibiotic Nanoparticles Using Supercritical CO2 as Antisolvent with Enhanced Mass Transfer

Chattopadhyay, P., & Gupta, R. B. (2001) · Industrial & Engineering Chemistry Research · doi:10.1021/ie010040r · Cited by 107 · see citing works

Interaction of alcohols with proteins

Bull, H. B., & Breese, K. (1978) · Biopolymers · doi:10.1002/bip.1978.360170907 · Cited by 103 · see citing works

Generation of Micro-Particles of Proteins for Aerosol Delivery Using High Pressure Modified Carbon Dioxide

Bustami, R., Chan, H., Dehghani, F., et al. (2000) · Pharmaceutical Research · doi:10.1023/a:1007551006782 · Cited by 99 · see citing works

Microencapsulation of protein particles within lipids using a novel supercritical fluid process

Santos, I. R. D., Richard, J., Pech, B., Thies, C., & Benoît, J. (2002) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00149-7 · Cited by 96 · see citing works

Applications of Supercritical Fluids in the Controlled Release of Drugs

Tom, J. W., Lim, G.-B., Debenedetti, P. G., & Prud'homme, R. K. (1992) · ACS Symposium Series · doi:10.1021/bk-1992-0514.ch019 · Cited by 96 · see citing works

Production of Protein-Loaded Polymeric Microcapsules by Compressed CO2 in a Mixed Solvent

Elvassore, N., Bertucco, A., & Caliceti, P. (2001) · Industrial & Engineering Chemistry Research · doi:10.1021/ie0004904 · Cited by 94 · see citing works

Supercritical fluid processing of proteins

Moshashaée, S., Bisrat, M., Forbes, R. T., et al. (2000) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(00)00108-1 · Cited by 86 · see citing works

Effective protein release from PEG/PLA nano-particles produced by compressed gas anti-solvent precipitation techniques

Caliceti, P., Salmaso, S., Elvassore, N., & Bertucco, A. (2003) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.10.015 · Cited by 84 · see citing works

Supercritical antisolvent process for substituted para-linked aromatic polyamides: phase equilibrium and morphology study

Yeo, S., Debenedetti, P. G., Radosz, M., et al. (1993) · Macromolecules · doi:10.1021/ma00075a012 · Cited by 80 · see citing works

Gas-liquid equilibrium for ethanol-water-carbon dioxide mixtures at elevated pressures

Gilbert, M. L., & Paulaitis, M. E. (1986) · Journal of Chemical & Engineering Data · doi:10.1021/je00045a012 · Cited by 76 · see citing works

Secondary Structure Characterization of Microparticulate Insulin Powders†

Yeo, S., Debenedetti, P. G., Patro, S. Y., et al. (1994) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600831203 · Cited by 76 · see citing works

Depressurization of an Expanded Liquid Organic Solution (DELOS): A New Procedure for Obtaining Submicron- or Micron-Sized Crystalline Particles

Ventosa, N., Sala, S., Veciana, J., et al. (2001) · Crystal Growth & Design · doi:10.1021/cg0155090 · Cited by 75 · see citing works

Micronization of insulin from halogenated alcohol solution using supercritical carbon dioxide as an antisolvent

Snavely, W. K., Subramaniam, B., Rajewski, R. A., & DeFelippis, M. R. (2002) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10193 · Cited by 75 · see citing works

Understanding factors that limit the productivity of suspension-based perfusion cultures operated at high medium renewal rates

Mercille, S., Johnson, M., Lanthier, S., Kamen, A., & Massie, B. (2000) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(20000220)67:4 · Cited by 66 · see citing works

Precipitation of Lysozyme Nanoparticles from Dimethyl Sulfoxide Using Carbon Dioxide as Antisolvent

Muhrer, G., & Mazzotti, M. (2003) · Biotechnology Progress · doi:10.1021/bp0256317 · Cited by 66 · see citing works

Putting principles into practice

Jamieson, J., Chapelle, C. A., & Preiss, S. (2004) · ReCALL · doi:10.1017/s0958344004001028 · Cited by 61 · see citing works

Improvement of Insulin Absorption from Intratracheally Administrated Dry Powder Prepared by Supercritical Carbon Dioxide Process

Todo, H., Iida, K., Okamoto, H., et al. (2003) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10497 · Cited by 42 · see citing works

Long-Term and High-Temperature Storage of Supercritically-Processed Microparticulate Protein Powders

Winters, M. A., Debenedetti, P. G., Carey, J., Sparks, H. G., Sane, S. U., & Przybycien, T. M. (1997) · Pharmaceutical Research · doi:10.1023/a:1012112503590 · Cited by 37 · see citing works

Supercritical fluid processing of proteins: lysozyme precipitation from aqueous solution

Moshashaée, S., Bisrat, M., Forbes, R. T., Quinn, É. Á., Nyqvist, H., & York, P. (2003) · Journal of Pharmacy and Pharmacology · doi:10.1211/002235702504 · Cited by 37 · see citing works

Conversion of citric acid to itaconic acid in a novel liquid membrane bioreactor

Bressler, E., & Braun, S. (2000) · Journal of Chemical Technology & Biotechnology · doi:10.1002/(sici)1097-4660(200001)75:1 · Cited by 35 · see citing works

Investigation of phase equilibrium for ternary systems containing ethanol, water and carbon dioxide at elevated pressures

Yao, S., Guan, Y., & Zhu, Z. (1994) · Fluid Phase Equilibria · doi:10.1016/0378-3812(94)80035-9 · Cited by 35 · see citing works

CF Science and Technology

Gallagher, P. M. (1989) · ACS symposium series · Cited by 35 · see citing works

Low-temperature manufacturing of fine pharmaceutical powders with supercritical fluid aerosolization in a Bubble Dryer®

Sievers, R. E., Huang, E. T. S., Villa, J. A., et al. (2001) · Pure and Applied Chemistry · doi:10.1351/pac200173081299 · Cited by 32 · see citing works

CO 2 and Fluorinated Solvent‐Based Technologies for Protein Microparticle Precipitation from Aqueous Solutions

Sarkari, M., Darrat, I., & Knutson, B. L. (2003) · Biotechnology Progress · doi:10.1021/bp0255513 · Cited by 29 · see citing works

Generation of Fine Powders of Recombinant Human Deoxyribonuclease Using the Aerosol Solvent Extraction System

Bustami, R., Chan, H., Sweeney, T. D., et al. (2003) · Pharmaceutical Research · doi:10.1023/b:pham.0000008053.69903.c1 · Cited by 28 · see citing works

Measurements and modeling of high-pressure phase behavior of binary CO2–amides systems

Byun, H., Kim, N., & Kwak, C. (2003) · Fluid Phase Equilibria · doi:10.1016/s0378-3812(02)00324-2 · Cited by 22 · see citing works

GRAM TO KILOGRAM SCALE-UP OF SUPERCRITICAL ANTI-SOLVENT PROCESS

Jung, J., Clavier, J.-Y., & Perrut, M. (2003) · Cited by 18 · see citing works

Supercritical Crystallisation - Volatile Components as ( Anti-)Solvents

Wubbolts, F. E. (2000) · Research Repository (Delft University of Technology) · Cited by 8 · see citing works

mRNA-lipid nanoparticle COVID-19 vaccines: structure and stability

Schoenmaker, L., Witzigmann, D., Kulkarni, J. A., Verbeke, R., Kersten, G., Jiskoot, W., & Crommelin, D. J. A. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120586 · Cited by 1,566 · see citing works

Delivery of Therapeutic Proteins

Pisal, D. S., Kosloski, M. P., & Balu-Iyer, S. V. (2010) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.22054 · Cited by 532 · see citing works

Applications of supercritical CO2 in the fabrication of polymer systems for drug delivery and tissue engineering

Davies, O. R., Lewis, A. L., Whitaker, M. J., Tai, H., Shakesheff, K. M., & Howdle, S. M. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.12.001 · Cited by 299 · see citing works

Supercritical phases of hydrogen

İbrahimoğlu, B., Sarıkaya, Y., Везироглу, А., et al. (2021) · International Journal of Hydrogen Energy · doi:10.1016/j.ijhydene.2021.07.032 · Cited by 16 · see citing works

Preparation of Microparticles with Supercritical Solution Precipitation Technology

Zhang, P. (2005) · Journal of Building Materials

Features of Near- and Supercritical Water

Nielsen, R. P., & Søgaard, E. G. (2013) · Current Physical Chemistry · doi:10.2174/18779468113036660010 · Cited by 1 · see citing works

Molecular dynamics study on the initial oxidation behavior of FeCr alloys in supercritical H2O and supercritical CO2 with O2

Guo, T., He, C., Liang, Z., et al. (2023) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2023.106110 · Cited by 15 · see citing works

Progress in Formation of Ultrafine Powder by Supercritical Fluid

Sun, Y. (2008) · Insulating Materials