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Cited by 118Schizophrenia research and treatmentMental Health and PsychiatryMental Health Treatment and Access

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Negative symptoms in first episode non‐affective psychosis

Malla, Ashok K., Takhar, Jatinder J., Norman, Ross M. G., Manchanda, Rahul, Cortese, Leonard, Haricharan, Raj, Verdi, Mary, Ahmed, Rashid·2002·Acta Psychiatrica Scandinavica
DOI 10.1034/j.1600-0447.2002.02139.x
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Abstract

Objective: To determine the prevalence of negative symptoms and to examine secondary sources of influence on negative symptoms and the role of specific negative symptoms in delay associated with seeking treatment in first episode non‐affective psychosis. Method: One hundred and ten patients who met Diagnostic Statistical Manual‐IV (DSM‐IV) criteria for a first episode of schizophrenia spectrum psychoses were rated for assessment of negative, positive, depressive and extrapyramidal symptoms, the premorbid adjustment scale and assessment of demographic and clinical characteristics including duration of untreated psychosis (DUP). Results: Alogia/flat affect and avolition/anhedonia were strongly influenced by parkinsonian and depressive symptoms, respectively. A substantial proportion (26.8%) of patients showed at a least moderate level of negative symptoms not confounded by depression and Parkinsonism. DUP was related only to avolition/anhedonia while flat affect/alogia was related to male gender, diagnosis of schizophrenia, age of onset and the length of the prodrome. Conclusion: Negative symptoms that are independent of the influence of positive symptoms, depression and extra pyramidal symptoms (EPS) are present in a substantial proportion of first episode psychosis patients and delay in seeking treatment is associated mainly with avolition and anhedonia.

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Crossref · 10.1034/j.1600-0447.2002.02139.x

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Research works printed but not linked: 3

  1. PERALTA MV, 1990, Sintomas esquizofrenicos positivos y negativos: un reanalisis del modelo dicotomos de la esquizofrenia, Actas Luso Esp Nevrol Psiquiatr Cienc A Fines, 18, 266
  2. TANDONR JIBSONMD TAYLORSF DEQUARDOJR.Conceptual models of the relationships between positive and negative symptoms.In: SHRIQUI CL NASRALLAH HA eds. Contemporary issues in the treatment of schizophrenia. Washington DC: American Psychiatric Press 1995:109–124.
  3. CHOUINARD G, 1980, Extrapyramidial symptom rating scale, Can J Neuro Sci, 7, 223

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Metadata

Authors
Malla, A. K., Takhar, J. J., Norman, R. M. G., Manchanda, R., Cortese, L., Haricharan, R., Verdi, M., & Ahmed, R.
Affiliations
Western University (CA)
Corresponding author
Malla, Ashok K.
ORCID
Venue
Acta Psychiatrica Scandinavica
Publisher
Wiley
Published
2002-06
Volume
105
Issue
6
Pages
431-439
ISSN
  • 0001-690X (ISSN-L)
  • 1600-0447
DOI
10.1034/j.1600-0447.2002.02139.x
OpenAlex
W2062522511
Cited by
118
References
37
Citations by year
2025: 3 · 2024: 2 · 2023: 3 · 2022: 9 · 2021: 2 · 2020: 4 · 2019: 6 · 2018: 3 · 2017: 4 · 2016: 6 · 2015: 5 · 2014: 5 · 2013: 8 · 2012: 14
FWCI
1.28
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 2305 d)
Locations
  • Acta Psychiatrica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Eli Lilly Canada
  • Canadian Institutes of Health Research
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords
negative symptoms, first-episode psychosis, schizophrenia, non-affective psychosis, alogia, flat affect, avolition, anhedonia, duration of untreated psychosis, treatment delay, depression, parkinsonism, extrapyramidal symptoms, prodromal symptoms, premorbid adjustment
MeSH terms
Adult, Affect, Female, Humans, Male, Psychiatric Status Rating Scales, Psychotic Disorders, Severity of Illness Index, Time Factors

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