Cited by 1,200Dermatology and Skin DiseasesReliability and Agreement in MeasurementContact Dermatitis and Allergies

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The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis

Hanifin, J. M., Thurston, M., Omoto, M., Cherill, R., Tofte, S. J., Graeber, M., Evaluator Group, The Easi·2001·Experimental Dermatology

DOI 10.1034/j.1600-0625.2001.100102.x

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Abstract

OBJECTIVE: To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency. DESIGN: Training of evaluators, application, and assessment over 2 consecutive days. SETTING: An academic center. PATIENTS: Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients > or = 8 years) and cohort 2 (10 patients < 8 years). INTERVENTIONS: None. MAIN OUTCOME MEASURE: The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed. RESULTS: Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days. CONCLUSIONS: This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.

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Diagnostic features of atopic dermatitis
Hanifin, J. M., & Rajka, G. (1980) · Acta Dermato-Venereologica · doi:10.2340/00015555924447 · Cited by 5,086
Self-citation
The Design and Analysis of Clinical Experiments
Fleiss, J. L. (1999) · Wiley eBooks · doi:10.1002/9781118032923 · Cited by 4,819
Severe Psoriasis – Oral Therapy with a New Retinoid
Fredriksson, T., & Pettersson, U. (2009) · Dermatologica · doi:10.1159/000250839 · Cited by 2,718
Severity Scoring of Atopic Dermatitis: The SCORAD Index
(2009) · Dermatology · doi:10.1159/000247298 · Cited by 2,304
Large sample standard errors of kappa and weighted kappa.
Fleiss, J. L., Cohen, J., & Everitt, B. S. (1969) · Psychological Bulletin · doi:10.1037/h0028106 · Cited by 1,536
Grading of the severity of atopic dermatitis.
Rajka, G., & Langeland, T. (1989) · PubMed · doi:10.2340/000155551441314 · Cited by 415
Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis
Sowden, J. M., Allen, B. R., Berth‐Jones, J., GRAHAM-BROWN, R. A. C., Motley, R., Finlay, A. Y., Salek, S., Marks, R., Ross, J., & Camp, R. D. R. (1991) · The Lancet · doi:10.1016/0140-6736(91)90134-b · Cited by 411
Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children
Kang, S., Lucky, A. W., Pariser, D. M., Lawrence, I., & Hanifin, J. M. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.109812 · Cited by 329
Self-citation
A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients
Paller, A. S., Eichenfield, L. F., Leung, D. Y. M., Stewart, D., & Appell, M. L. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.109813 · Cited by 323
Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: Part I, efficacy
Hanifin, J. M., LING, M. R., Langley, R. G. B., Breneman, D., & Rafal, E. S. (2001) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2001.109810 · Cited by 285
Self-citation

Show all 17 references

Research works printed but not linked: 1

Fleiss J L, 1986, New York., 1

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Difamilast Ointment in Japanese Adult and Pediatric Patients with Atopic Dermatitis: A Phase III, Long-Term, Open-Label Study
Saeki, H., Imamura, T., Yokota, D., & Tsubouchi, H. (2022) · Dermatology and Therapy · doi:10.1007/s13555-022-00751-9 · Cited by 24
IgG from Adult Atopic Dermatitis (AD) Patients Induces Thymic IL-22 Production and CLA Expression on CD4+ T Cells: Possible Epigenetic Implications Mediated by miRNA
de Sousa, T. R., Fagundes, B. O., Nascimento, A., Fernandes, L. A., Sgnotto, F. D. R., Orfali, R. L., Aoki, V., Duarte, A. J. D. S., Sanabani, S. S., & Victor, J. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126867 · Cited by 24
Efficiency of a new hybrid multi-soil-layering eco-friendly technology for removing pollutants from domestic wastewater under an arid climate
Zidan, K., Mandi, L., Hejjaj, A., Sbahi, S., Fels, A. E. A. E., Ouazzani, N., & Assabbane, A. (2023) · Journal of Water Process Engineering · doi:10.1016/j.jwpe.2022.103482 · Cited by 24
The validity and reliability of the occupational contact dermatitis disease severity index
Curr, N., Dharmage, S. C., Keegel, T. G., Lee, A., Saunders, H., & Nixon, R. L. (2008) · Contact Dermatitis · doi:10.1111/j.1600-0536.2008.01404.x · Cited by 24
The Traditional Chinese Medicine and Relevant Treatment for the Efficacy and Safety of Atopic Dermatitis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Shi, Z., Song, T., Xie, J., Yan, Y., & Du, Y.-P. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/6026434 · Cited by 24
East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor: A New Therapeutic Option in the Treatment of Inflammatory Skin Disease
Sharma, M., Levenson, C., Browning, J., Becker, E. M., Clements, I., Castella, P., & Cox, M. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00200 · Cited by 24
Staphylococcal enterotoxins modulate the effector CD4+ T cell response by reshaping the gene expression profile in adults with atopic dermatitis
Orfali, R. L., Yoshikawa, F. S. Y., Oliveira, L. M. D. S., Pereira, N. Z., de Lima, J. F., Ramos, Y. Á. L., Duarte, A. J. D. S., Sato, M. N., & Aoki, V. (2019) · Scientific Reports · doi:10.1038/s41598-019-49421-5 · Cited by 24
Reliéva, a Mahonia Aquifolium Extract for the Treatment of Adult Patients With Atopic Dermatitis
Donsky, H. J., & Clarke, D. (2007) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e31814002c1 · Cited by 24
The effects of fumaria parviflora L extract on chronic hand eczema: a randomized double-blind placebo controlled clinical trial.
Jowkar, F., Jamshidzadeh, A., Yazdi, A. M., & Pasalar, M. (2011) · Europe PMC (PubMed Central) · Cited by 24
A multicenter trial of the efficacy and safety of 0.03% tacrolimus ointment for atopic dermatitis in Korea
Won, C., Seo, P., Park, Y. M., Yang, J., Lee, K.-W., Sung, K.-J., Park, C. W., Kim, D. W., Chang, H., Won, Y., et al. (2004) · Journal of Dermatological Treatment · doi:10.1080/09546630310020812 · Cited by 24
Leflunomide as a novel treatment option in severe atopic dermatitis
Schmitt, J. M., Wozel, G., & Pfeiffer, C. (2004) · British Journal of Dermatology · doi:10.1111/j.0007-0963.2003.05846.x · Cited by 24
Educational intervention and atopic dermatitis: impact on quality of life and treatment
Muzzolon, M., Robl, R., Canato, M., Abagge, K. T., & Carvalho, V. O. (2021) · Asia Pacific Allergy · doi:10.5415/apallergy.2021.11.e21 · Cited by 23
General and Skin-Specific Health-Related Quality of Life in Patients With Atopic Dermatitis Before and During the COVID-19 Pandemic
Koszorú, K., Hajdu, K., Brodszky, V., Szabó, Á., Borza, J., Bodai, K., Pónyai, G., Szegedi, A., Sárdy, M., & Rencz, F. (2022) · Dermatitis · doi:10.1097/der.0000000000000908 · Cited by 23
Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model
Kim, W.-K., Jang, Y. J., Park, S., Min, S.-G., Kwon, H., Jo, M. J., & Ko, G. (2024) · The Journal of Microbiology · doi:10.1007/s12275-024-00104-5 · Cited by 23
Verminderte berufliche Leistungsfähigkeit und Lebensqualität bei Patienten mit moderater bis schwerer Neurodermitis
Haufe, E., Abraham, S., Heratizadeh, A., Harder, I., Zink, A., Weißhaar, E., Kleinheinz, A., von Kiedrowski, R., Worm, M., Bell, M., et al. (2018) · Der Hautarzt · doi:10.1007/s00105-018-4261-z · Cited by 23
Clinical Features and Disease Management in Adult Patients With Atopic Dermatitis Receiving Care at Reference Hospitals in Brazil: the ADAPT Study
Arruda, L. K., Yang, A. C., Aoki, V., Criado, R. F. J., Pires, M. C., Lupi, O., Fabrício, L. H. Z., Richman, D., & Silvi, S. (2020) · Journal of Investigational Allergology and Clinical Immunology · doi:10.18176/jiaci.0478 · Cited by 23
EczemaNet: Automating Detection and Severity Assessment of Atopic Dermatitis
Pan, K., Hurault, G., Arulkumaran, K., Williams, H. C., & Tanaka, R. J. (2020) · Lecture notes in computer science · doi:10.1007/978-3-030-59861-7_23 · Cited by 23
Definition of treatment goals in terms of clinician-reported disease severity and patient-reported outcomes in moderate-to-severe adult atopic dermatitis: a systematic review
Iannone, M., Tonini, G., Janowska, A., Dini, V., & Romanelli, M. (2021) · Current Medical Research and Opinion · doi:10.1080/03007995.2021.1933929 · Cited by 23
Disease severity evaluation among dermatological out‐patients: a comparison between the assessments of patients and physicians
Tabolli, S., Sampogna, F., Pagliarello, C., Paradisi, A., Spagnoli, A., & ABENI, D. D. (2011) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2011.04038.x · Cited by 23
Morus alba L. suppresses the development of atopic dermatitis induced by the house dust mite in NC/Nga mice
Lim, H., Ha, H., Lee, H., Lee, J. K., Lee, M.-Y., & Shin, H. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-139 · Cited by 23
Omalizumab treatment in severe adult atopic dermatitis.
Thaiwat, S., & Sangasapaviliya, A. (2011) · PubMed · Cited by 23
Clinical Management of Atopic Eczema with Pimecrolimus Cream 1% (Elidel®) in Paediatric Patients
Eichenfield, L. F., Thaçi, D., Prost, Y. D., Puig, L., & Paul, C. F. (2007) · Dermatology · doi:10.1159/000102116 · Cited by 23
A phase 2, randomized, double‐blind, vehicle‐controlled trial of tapinarof cream in Japanese pediatric patients with atopic dermatitis
Igarashi, A., Tsuji, G., Murata, R., Fukasawa, S., & Yamane, S. (2024) · The Journal of Dermatology · doi:10.1111/1346-8138.17587 · Cited by 22
Artificial intelligence in clinical data analysis: A review of large language models, foundation models, digital twins, and allergy applications
Fuse, Y., Murphy, S. N., Ikari, H., Takahashi, A., Fuse, K., & Kawakami, E. (2025) · Allergology International · doi:10.1016/j.alit.2025.06.005 · Cited by 25
Choice of Moisturiser for Eczema Treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care
Ridd, M. J., Garfield, K., Gaunt, D., Hollinghurst, S. P., Redmond, N. M., Powell, K., Wilson, V. J., Guy, R. H., Ball, N., Shaw, L., et al. (2016) · BMJ Open · doi:10.1136/bmjopen-2016-012021 · Cited by 22
Comorbidities and treatment patterns in adult patients with atopic dermatitis: results from a nationwide multicenter study
Campanati, A., Bianchelli, T., Gesuita, R., Foti, C., Malara, G., Micali, G., Amerio, P., Rongioletti, F., Corazza, M., Patrizi, A., et al. (2021) · Archives of Dermatological Research · doi:10.1007/s00403-021-02243-w · Cited by 22
Effects of a novel formulation of fluocinonide 0.1% cream on skin barrier function in atopic dermatitis.
Woods, M. T., Brown, P. A., Baig-Lewis, S., & Simpson, E. L. (2011) · PubMed · Cited by 22
Staphylococcus Infection: Relapsing Atopic Dermatitis and Microbial Restoration
Hulme, J. (2023) · Antibiotics · doi:10.3390/antibiotics12020222 · Cited by 22
Rademikibart ( CBP ‐201), a next‐generation monoclonal antibody targeting human IL‐4Rα : Two phase I randomized trials, in healthy individuals and patients with atopic dermatitis
Wang, J., White, J., Sansone, K. J., Spelman, L. J., Sinclair, R. D., Yang, X., Pan, W., & Wei, Z. (2023) · Clinical and Translational Science · doi:10.1111/cts.13656 · Cited by 22
Effectiveness of Inpatient Treatment on Quality of Life and Clinical Disease Severity in Atopic Dermatitis and Psoriasis Vulgaris – A Prospective Study
Schmitt, J. M., Heese, E., Wozel, G., & Meurer, M. (2006) · Dermatology · doi:10.1159/000096916 · Cited by 22
Vitreoscilla filiformis bacterial extract to improve the efficacy of emollient used in atopic dermatitis symptoms
Guéniche, A., Dahel, K., Bastien, P., Martin, R. J., Nicolas, J., & Breton, L. (2007) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2007.02428.x · Cited by 22
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trial
Marseglia, A., Licari, A., Agostinis, F., Barcella, A., Bonamonte, D., Puviani, M., Milani, M., & Marseglia, G. L. (2014) · Pediatric Allergy and Immunology · doi:10.1111/pai.12185 · Cited by 22
A randomized, controlled trial comparing topical steroid application to wet versus dry skin in children with atopic dermatitis (AD)
Kohn, L. L., Kang, Y., & Antaya, R. J. (2016) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2016.04.060 · Cited by 22
Serum IL-21 levels are elevated in atopic dermatitis patients with acute skin lesions
Mizutani, H., Tamagawa‐Mineoka, R., Nakamura, N., Masuda, K., & Katoh, N. (2016) · Allergology International · doi:10.1016/j.alit.2016.10.010 · Cited by 22
Validation of four single-item patient-reported assessments of sleep in adult atopic dermatitis patients
Lei, D. K., Yousaf, M., Janmohamed, S. R., Vakharia, P. P., Chopra, R., Chavda, R., Gabriel, S., Sacotte, R. M., Patel, K. R., Singam, V., et al. (2019) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2019.12.002 · Cited by 22
Efficacy, Safety, and Immunomodulatory Effect of the Intramuscular Administration of Autologous Total Immunoglobulin G for Atopic Dermatitis: A Randomized Clinical Trial
Nahm, D., Ye, Y., Shin, Y. S., Park, H., Kim, M., Kwon, B., Cho, S.-M., & Han, J. (2020) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2020.12.6.949 · Cited by 22

Authors: Hanifin, J. M., Thurston, M., Omoto, M., Cherill, R., Tofte, S. J., Graeber, M., & Evaluator Group, T. E.
Affiliations: Oregon Health & Science University (US)
Novartis (Switzerland) (CH)
Shiga University of Medical Science (JP)
Corresponding author: Hanifin, J. M.
ORCID: Hanifin, J. M.
Venue: Experimental Dermatology
Publisher: Wiley
Published: 2001-02
Volume: 10
Issue: 1
Pages: 11-18
ISSN: 0906-6705 (ISSN-L)
1600-0625
DOI: 10.1034/j.1600-0625.2001.100102.x
OpenAlex: W2117359358
Cited by: 1,200
References: 17
Citations by year: 2026: 69 · 2025: 85 · 2024: 92 · 2023: 101 · 2022: 84 · 2021: 98 · 2020: 82 · 2019: 63 · 2018: 47 · 2017: 46 · 2016: 53 · 2015: 28 · 2014: 43 · 2013: 23 · 2012: 21
FWCI: 20.78
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 2713 d)
Locations: Experimental Dermatology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Reliability and Agreement in Measurement
Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
Keywords: Eczema Area and Severity Index, atopic dermatitis, inter-rater reliability, intra-rater reliability, disease severity assessment, disease extent assessment, clinical trial outcome measures
MeSH terms: Adolescent, Adult, Child, Child, Preschool, Dermatitis, Atopic, Dermatology, Eczema, Humans, Infant, Infant, Newborn, Severity of Illness Index, Reproducibility of Results, Cohort Studies, Observer Variation

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The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis

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