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Cited by 149Treatment of Major DepressionMental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Probability of relapse after recovery from an episode of depression

Lewinsohn, Peter M., Zeiss, Antonette M., Duncan, Edward M.·1989·Journal of Abnormal Psychology
DOI 10.1037/0021-843x.98.2.107
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Abstract

Examined relapse rates in those individuals who have experienced an episode of unipolar depression as a function of the number of previous episodes, gender, age at onset of the episode (less than 40 vs. greater than 40), time since a previous episode, and depression level at time of interview. From of 6,742 participants, 2,046 were interviewed; of these, 1,130 had at least one, 513 reported a second and 173 reported a third episode. The probability for relapse was positively related to number of previous episodes, being female, depression level at time of interview, but not to age at onset (less than 40 vs. greater than 40). Women were also more likely to have more severe episodes. Participants with elevated depression symptoms reported a greater number of previous episodes. Following the first episode, there was a decline in hazard rate for men but not women; following the second episode, there was no change in vulnerability for men; for women, the results were ambiguous.

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  • Results of studies on sociodemographic factors (age, gender, socioeconomic status, marital status) as risk factors for recurrence have been inconsistent.

    “Many studies showed that sociodemographic factors such as younger age, women, and those who have never been married were at higher risk of recurrence [7, 11–15]; however, results of other studies on these risk factors have been inconsistent.”

    From Predictors of recurrence of major depressive disorder (2020) · cites this paper as [17]

  • In our study, age at onset of first MDE and gender did not predict subsequent episode of MDE.

    “In terms of age at onset and gender, the results of our study replicated results of several earlier studies showing that age at onset of first MDE [17, 18, 59–60] and gender [16, 18, 59–61] did not predict subsequent episode of MDE.”

    From Predictors of recurrence of major depressive disorder (2020) · cites this paper as [17]

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Authors
Lewinsohn, P. M., Zeiss, A. M., & Duncan, E. M.
Affiliations
Oregon Research Institute (US)
ORCID
Zeiss, Antonette M.
Venue
Journal of Abnormal Psychology
Publisher
American Psychological Association (APA)
Published
1989-05
Volume
98
Issue
2
Pages
107-116
ISSN
  • 0021-843X (ISSN-L)
  • 1939-1846
DOI
10.1037/0021-843x.98.2.107
OpenAlex
W2022630246
Cited by
149
References
0
Citations by year
2025: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 5 · 2013: 3 · 2012: 1
FWCI
3.89
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Abnormal Psychology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Mental Health (MH 35672)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
relapse, major depressive disorder, recurrent depression, gender differences, age of onset, depression severity, hazard function
MeSH terms
Actuarial Analysis, Adolescent, Adult, Aged, Depressive Disorder, Female, Humans, Male, Middle Aged, Oregon, Probability, Recurrence, Retrospective Studies, Sex Factors

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