The DOI matches its Crossref record; 326 of the 331 references it cites were found in a registry or an index.
The evidence for a neurobiological model of childhood antisocial behavior
Open accessAbstract
Children with persistent antisocial and aggressive behavior are diagnosed as having disruptive behavior disorder. The authors review evidence that antisocial children, and especially those who persist with this behavior as they grow older, have a range of neurobiological characteristics. It is argued that serotonergic functioning and stress-regulating mechanisms are important in explaining individual differences in antisocial behavior. Moreover, low fear of punishment and physiological underactivity may predispose antisocial individuals to seek out stimulation or take risks and may help to explain poor conditioning and socialization. The authors propose a theoretical model highlighting the interplay between neurobiological deficits and cognitive and emotional functioning as mediators of the link between early adversity and antisocial behavior problems in childhood. Implications for intervention programs are discussed.
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“Serotonin is an upstream modulator of SRS activity through its action on the amygdala and hypothalamus; serotonergic neurotransmission, in turn, is reciprocally affected by cortisol (Porter et al., 2004; van Goozen et al., 2007)”
From The Adaptive Calibration Model of stress responsivity (2011) · cites this paper as van Goozen et al., 2007
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Grote, N. K., Bridge, J. A., Gavin, A. R., Melville, J. L., Iyengar, S., & Katon, W. J. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.111 · Cited by 1,882
The Adaptive Calibration Model of stress responsivity
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Stress response and the adolescent transition: performance versus peer rejection stressors
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Oberle, E., & Schonert-Reichl, K. A. (2016) · Social Science & Medicine · doi:10.1016/j.socscimed.2016.04.031 · Cited by 524
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Metadata
- Authors
- van Goozen, S. H. M., Fairchild, G., Snoek, H., & Harold, G. T.
- Affiliations
- University of Cambridge (GB)
- University Medical Center Utrecht (NL)
- Cardiff University (GB)
- ORCID
- Fairchild, Graeme
- Venue
- Psychological Bulletin
- Published
- 2007
- Volume
- 133
- Issue
- 1
- Pages
- 149-182
- ISSN
- 0033-2909 (ISSN-L)
- 1939-1455
- OpenAlex
- W2108307535
- Cited by
- 475
- References
- 331
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 7 · 2023: 13 · 2022: 12 · 2021: 18 · 2020: 21 · 2019: 21 · 2018: 27 · 2017: 28 · 2016: 32 · 2015: 35 · 2014: 34 · 2013: 42 · 2012: 34
- FWCI
- 34.10
- Type
- journal article
- Language
- en
- Open access
- green
- figshare.com
- Licence
- cc-by
- Locations
- Psychological Bulletin (publishedVersion)
- PubMed (publishedVersion)
- Figshare (submittedVersion, cc-by)
- Leicester Research Archive (University of Leicester) (submittedVersion)
- Funders
- Wellcome Foundation
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Keywords
- childhood antisocial behavior, disruptive behavior disorders, neurobiological model, fear of punishment, childhood adversity, risk-taking, socialization
- MeSH terms
- Adrenocorticotropic Hormone, Amygdala, Antisocial Personality Disorder, Brain, Child, Humans
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