The DOI matches its Crossref record; 280 of the 280 references it cites were found in a registry or an index.
Neuropsychological impairments in schizophrenia: Integration of performance-based and brain imaging findings.
Abstract
Until recently, the dominant view was that schizophrenia patients have limited, if any, neuropsychological impairments, and those that are observed are only secondary to the florid symptoms of the disorder. This view has dramatically changed. This review integrates recent evidence demonstrating the severity and profile of neuropsychological impairments in schizophrenia. We present quantitative evaluation of the literature demonstrating that the most severe impairments are apparent in episodic memory and executive control processes, evident on a background of a generalized cognitive deficit. The neuropsychological impairments potentially represent genetic liability to the disorder, as similar, yet milder, impairments are evident in schizophrenia patients even before the onset of psychotic symptoms, as well as in the nonpsychotic relatives of schizophrenia patients. Corresponding cognitive neuroimaging literature on executive functions, episodic memory, and working memory in schizophrenia documenting abnormalities in frontal and medial temporal lobes is summarized, and current models integrating neuropsychological and neuroimaging data are discussed.
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Cited by
Maruff, P., Thomas, E., Cysique, L., Brew, B., Collie, A., Snyder, P., & Pietrzak, R. H. (2009) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acp010 · Cited by 635
The global cognitive impairment in schizophrenia: consistent over decades and around the world
Schaefer, J., Giangrande, E., Weinberger, D. R., & Dickinson, D. (2013) · Schizophrenia Research · doi:10.1016/j.schres.2013.07.009 · Cited by 605
Crippa, J. A. S., Derenusson, G. N., Ferrari, T. B., Wichert-Ana, L., Duran, F. L., Martin-Santos, R., Simões, M. V., Bhattacharyya, S., Fusar-Poli, P., Atakan, Z., et al. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881110379283 · Cited by 535
Evidence of a dimensional relationship between schizotypy and schizophrenia: A systematic review
Nelson, M. T., Seal, M. L., Pantelis, C., & Phillips, L. J. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.01.004 · Cited by 334
What Do We Know About Neuropsychological Aspects Of Schizophrenia?
Palmer, B. W., Dawes, S. E., & Heaton, R. K. (2009) · Neuropsychology Review · doi:10.1007/s11065-009-9109-y · Cited by 316
Metadata
- Authors
- Reichenberg, A., & Harvey, P. D.
- Venue
- Psychological Bulletin
- Published
- 2007
- Volume
- 133
- Issue
- 5
- Pages
- 833-858
- ISSN
- 0033-2909 (ISSN-L)
- 1939-1455
- OpenAlex
- W2088865133
- Cited by
- 532
- References
- 280
- FWCI
- 17.65
- Type
- journal article
- Language
- en
- Open access
- closed
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