Intact and long-lasting repetition priming in amnesia.

Abstract

In 2 experiments, we evaluated the ability of amnesic patients to exhibit long-lasting perceptual priming after a single exposure to pictures. Ss named pictures as quickly as possible on a single occasion, and later named the same pictures mixed with new pictures. In Experiment 1, amnesic patients exhibited fully intact priming effects lasting at least 7 days. In Experiment 2, the priming effect for both groups was shown to depend on both highly specific visual information and on less visual, more conceptual information. In contrast, recognition memory was severely impaired in the patients, as assessed by both accuracy and response time. The results provide the first report of a long-lasting priming effect in amnesic patients, based on a single encounter, which occurs as strongly in the patients as in normal Ss. Together with other recent findings, the results suggest that long-lasting priming and recognition memory depend on separate brain systems.

Cites (6)

1. Distributed hierarchical processing in the primate cerebral cortex
   Felleman, D. J., Van Essen, D. C. · 1991 · Cerebral Cortex
2. Recognition-by-components: A theory of human image understanding.
   Biederman, Irving · 1987 · Psychological Review
3. The Medial Temporal Lobe Memory System
   Squire, Larry R., Zola-Morgan, Stuart · 1991 · Science
4. Implicit memory: History and current status.
   Schacter, Daniel L. · 1987 · Journal of Experimental Psychology: Learning, Memory, and Cognition
5. Preserved Learning and Retention of Pattern-Analyzing Skill in Amnesia: Dissociation of Knowing How and Knowing That
   Cohen, Neal J., Squire, Larry R. · 1980 · Science
6. The functional logic of cortical connections
   Zeki, S., Shipp, S. · 1988 · Nature

Show all 6 references

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3. The Structure and Organization of Memory
   Squire, L. R., Knowlton, B., Musen, G. · 1993 · Annual Review of Psychology
4. Three Cases of Enduring Memory Impairment after Bilateral Damage Limited to the Hippocampal Formation
   Rempel-Clower, Nancy L., Zola, Stuart M., Squire, Larry R., Amaral, David G. · 1996 · The Journal of Neuroscience
5. COGNITIVE NEUROSCIENCE OF HUMAN MEMORY
   Gabrieli, J. D. E. · 1998 · Annual Review of Psychology

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