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The differentiation of semantic dementia and frontal lobe dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer's disease: a comparative neuropsychological study
Abstract
The authors compared age-matched groups of patients with the frontal and temporal lobe variants of frontotemporal dementia (FTD; dementia of frontal type [DFT] and semantic dementia), early Alzheimer's disease (AD), and normal controls (n = 9 per group) on a comprehensive neuropsychological battery. A distinct profile emerged for each group: Those with AD showed a severe deficit in episodic memory with more subtle, but significant, impairments in semantic memory and visuospatial skills; patients with semantic dementia showed the previously documented picture of isolated, but profound, semantic memory breakdown with anomia and surface dyslexia but were indistinguishable from the AD group on a test of story recall; and the DFT group were the least impaired and showed mild deficits in episodic memory and verbal fluency but normal semantic memory. The frontal and temporal presentations of FTD are clearly separable from each other and from early AD.
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“while temporal lobe damage impairs semantic category fluency to a greater extent than letter fluency (e.g. Hodges et al. 1999; Newcombe, 1969, Butters et al.; 1987; Monsch, 1994; Chan et al; 1993; Baldo et al., 2006).”
From Neural systems supporting lexical search guided by letter and semantic category cues: a self-paced overt response fMRI study of verbal fluency (2010) · cites this paper as Hodges et al. 1999
In the citing paper
“Studies have shown, for example, that frontal lobe damage results in disproportionate impairment to letter fluency (e.g. Hodges et al., 1999; Miller, 1984; Baldo et al. 2001; Moscovitch et al., 1994)”
From Neural systems supporting lexical search guided by letter and semantic category cues: a self-paced overt response fMRI study of verbal fluency (2010) · cites this paper as Hodges et al., 1999
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Cites
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
Neuropathological stageing of Alzheimer-related changes.
Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123
Snodgrass, J. G., & Vanderwart, M. (1980) · Journal of Experimental Psychology Human Learning & Memory · doi:10.1037//0278-7393.6.2.174 · Cited by 5,604
Peter, H., Penzel, T., Peter, J. H., & Peter, J. G. (2025) · Springer Reference Medizin · doi:10.1007/978-3-662-65186-5_302294 · Cited by 2,278
SEMANTIC DEMENTIA: PROGRESSIVE FLUENT APHASIA WITH TEMPORAL LOBE ATROPHY
HODGES, J. R., PATTERSON, K., OXBURY, S., & FUNNELL, E. (1992) · Brain · doi:10.1093/brain/115.6.1783 · Cited by 1,710
Neural correlates of category-specific knowledge
Martin, A. D., Wiggs, C. L., Ungerleider, L. G., & Haxby, J. V. (1996) · Nature · doi:10.1038/379649a0 · Cited by 1,575
Severe disturbance of higher cognition after bilateral frontal lobe ablation: Patient EVR
Eslinger, P. J., & Damasio, A. R. (1985) · Neurology · doi:10.1212/wnl.35.12.1731 · Cited by 1,426
Slowly progressive aphasia without generalized dementia
Mesulam, M. (1982) · Annals of Neurology · doi:10.1002/ana.410110607 · Cited by 1,241
Functional anatomy of a common semantic system for words and pictures
Vandenberghe, R. R., Price, C. J., Wise, R., Josephs, O., & Frackowiak, R. S. J. (1996) · Nature · doi:10.1038/383254a0 · Cited by 1,172
Discrete Cortical Regions Associated with Knowledge of Color and Knowledge of Action
Martin, A. D., Haxby, J. V., Lalonde, F. M., Wiggs, C. L., & Ungerleider, L. G. (1995) · Science · doi:10.1126/science.270.5233.102 · Cited by 1,079
Semantic dementia: A form of circumscribed cerebral atrophy
Snowden, J. S., Goulding, P., & Neary, D. (1989) · Behavioural Neurology · doi:10.1155/1989/124043 · Cited by 926
Welsh-Bohmer, K. A., Butters, N., Hughes, J. P., Mohs, R. C., & Heyman, A. (1991) · Archives of Neurology · doi:10.1001/archneur.1991.00530150046016 · Cited by 721
Semantic memory impairment in Alzheimer's disease: Failure of access or degraded knowledge?
Hodges, J. R., Salmon, D. P., & Butters, N. (1992) · Neuropsychologia · doi:10.1016/0028-3932(92)90104-t · Cited by 647
Hodges, J. R. (1995) · Neuropsychologia · doi:10.1016/0028-3932(94)00127-b · Cited by 644
Dementia of frontal lobe type.
Neary, D., Snowden, J. S., Northen, B., & Goulding, P. (1988) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.51.3.353 · Cited by 553
Detection and Staging of Dementia in Alzheimer's Disease
Welsh-Bohmer, K. A. (1992) · Archives of Neurology · doi:10.1001/archneur.1992.00530290030008 · Cited by 473
Charting the progression in semantic dementia: Implications for the organisation of semantic memory
Hodges, J. R., Graham, N. L., & Patterson, K. E. (1995) · Memory · doi:10.1080/09658219508253161 · Cited by 440
Graham, K. S., & Hodges, J. R. (1997) · Neuropsychology · doi:10.1037/0894-4105.11.1.77 · Cited by 421
Functional Neuroanatomy of the Semantic System: Divisible by What?
Mummery, C. J., Patterson, K. E., Hodges, J. R., & Price, C. J. (1998) · Journal of Cognitive Neuroscience · doi:10.1162/089892998563059 · Cited by 394
Disrupted temporal lobe connections in semantic dementia
Mummery, C. J., Patterson, K. E., Wise, R. J. S., Vandenbergh, R., Price, C. J., & Hodges, J. R. (1999) · Brain · doi:10.1093/brain/122.1.61 · Cited by 387
Dementia lacking distinctive histologie features
Knopman, D. S., Mastri, A. R., Frey, W. H., Sung, J. H., & Rustan, T. D. (1990) · Neurology · doi:10.1212/wnl.40.2.251 · Cited by 377
Miller, B. L., Cummings, J. L., Villanueva‐Meyer, J., Boone, K. W., Mehringer, C. M., Lesser, I. M., & Mena, I. G. (1991) · Neurology · doi:10.1212/wnl.41.9.1374 · Cited by 364
Snowden, J. S., Neary, D., & Mann, D. M. A. (1996) · Churchill Livingstone eBooks · Cited by 339
Deterioration of word meaning: Implications for reading
Patterson, K. E., & Hodges, J. R. (1992) · Neuropsychologia · doi:10.1016/0028-3932(92)90096-5 · Cited by 338
Generating ‘tiger’ as an animal name or a word beginning with T: differences in brain activation
Mummery, C. J., Patterson, K. E., Hodges, J. R., & Wise, R. J. S. (1996) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1996.0146 · Cited by 316
Nonfluent progressive aphasia and semantic dementia: A comparative neuropsychological study
Hodges, J. R., & Patterson, K. E. (1996) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700001685 · Cited by 301
Rosser, A., & Hodges, J. R. (1994) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.11.1389 · Cited by 296
Greene, J. D. W., Baddeley, A. D., & Hodges, J. R. (1996) · Neuropsychologia · doi:10.1016/0028-3932(95)00151-4 · Cited by 277
The Impact of Semantic Memory Loss on Phonological Representations
Patterson, K. E., Graham, N. L., & Hodges, J. R. (1994) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1994.6.1.57 · Cited by 234
Loss of semantic memory: implications for the modularity of mind
Hodges, J. R., Patterson, K. E., & TYLER, L. K. (1994) · Cognitive Neuropsychology · doi:10.1080/02643299408251984 · Cited by 190
Snowden, J. S., Griffiths, H. L., & Neary, D. (1996) · Cognitive Neuropsychology · doi:10.1080/026432996381674 · Cited by 183
Pick's disease and Pick complex
KERTESZ, A. E., & Muñoz, D. G. (1998) · Cited by 182
Alzheimer Disease, Attention, and the Cholinergic System
Lawrence, A. D., & Sahakian, B. J. (1995) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-199501002-00008 · Cited by 169
Comparison of neuropsychological functioning in Alzheimer’s disease and frontotemporal dementia
Pachana, N. A., Boone, K. B., Miller, B. L., Cummings, J. L., & Berman, N. (1996) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700001673 · Cited by 154
The relationship between comprehension and oral reading in progressive fluent aphasia
Graham, K. S., Hodges, J. R., & Patterson, K. E. (1994) · Neuropsychologia · doi:10.1016/0028-3932(94)90133-3 · Cited by 125
Lexical and Semantic Binding Effects in Short-term Memory: Evidence from Semantic Dementia
Knott, R., Patterson, K. E., & Hodges, J. R. (1997) · Cognitive Neuropsychology · doi:10.1080/026432997381303 · Cited by 113
Hodges, J. R., & Patterson, K. E. (1997) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(97)01022-x · Cited by 98
Spared and Impaired Cognitive Abilities After Bilateral Frontal Damage
Brazzelli, M. G., Colombo, N., Sala, S. D., & Spinnler, H. R. (1994) · Cortex · doi:10.1016/s0010-9452(13)80323-1 · Cited by 96
Heterogeneity of Alzheimer’s Disease
(1992) · Research and perspectives in Alzheimer's disease · doi:10.1007/978-3-642-46776-9 · Cited by 93
Quantification of cortical atrophy in a case of progressive fluent aphasia
Harasty, J., Halliday, G. M., Halliday, G. M., Code, C., & Brooks, W. S. (1996) · Brain · doi:10.1093/brain/119.1.181 · Cited by 68
Dementia of the frontal type: neuropsychological and [99Tc]-HM-PAO SPET features.
Frisoni, G. B., Pizzolato, G., Geroldi, C., Rossato, A., Bianchetti, A., & Trabucchi, M. (1995) · PubMed · Cited by 67
Graham, K. S., Becker, J. T., & Hodges, J. R. (1997) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617797005341 · Cited by 61
Elfgren, C., Brun, A. E., Gustafson, L., Johanson, A. M., Minthon, L., Passant, U., & Risberg, J. (1994) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.930090807 · Cited by 58
Dementia of frontal type and the focal lobar atrophies
Gregory, C. A., & Hodges, J. R. (1993) · International Review of Psychiatry · doi:10.3109/09540269309037801 · Cited by 46
Executive functions and Alzheimer's disease: problems and prospects
Patterson, M. B., Mack, J. L., Geldmacher, D., & Whitehouse, P. J. (1996) · European Journal of Neurology · doi:10.1111/j.1468-1331.1996.tb00182.x · Cited by 44
Senile Hirnatrophie als Grundlage von Herderscheinungen
Pick, A., Girling, D. M., & Markova, I. (1995) · History of Psychiatry · doi:10.1177/0957154x9500602410 · Cited by 43
On the relationship between senile cerebral atrophy and aphasia
Pick, A., Girling, D. M., & Berríos, G. E. (1994) · History of Psychiatry · doi:10.1177/0957154x9400502007 · Cited by 24
On the symptomatology of left-sided temporal lobe atrophy
Pick, A. J., Girling, D. M., & Berríos, G. E. (1997) · History of Psychiatry · doi:10.1177/0957154x9700802910 · Cited by 21
Disrupted temporal lobe connections in semantic dementia
Mummery, C. J., Patterson, K. E., Price, C. J., & Hodges, J. (1998) · NeuroImage · doi:10.1016/s1053-8119(18)31038-3 · Cited by 7
Christensen (1997) · doi:10.1002/(sici)1099-1166(199703)12:3
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Metadata
- Authors
- Hodges, J. R., Patterson, K., Ward, R., Garrard, P., Bak, T., Perry, R., & Gregory, C.
- Affiliations
- University of Cambridge (GB)
- Venue
- Neuropsychology
- Published
- 1999
- Volume
- 13
- Issue
- 1
- Pages
- 31-40
- ISSN
- 0894-4105 (ISSN-L)
- 1931-1559
- OpenAlex
- W2030202961
- Cited by
- 335
- References
- 50
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 8 · 2020: 8 · 2019: 7 · 2018: 8 · 2017: 12 · 2016: 11 · 2015: 19 · 2014: 10 · 2013: 14 · 2012: 16
- FWCI
- 10.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- semantic dementia, frontotemporal dementia, early Alzheimer's disease, differential diagnosis, episodic memory, semantic memory, visuospatial ability, anomia, surface dyslexia, story recall, verbal fluency
- MeSH terms
- Age Factors, Aged, Atrophy, Cognition Disorders, Dementia, Female, Frontal Lobe, Humans, Male, Middle Aged, Neuropsychological Tests, Semantics, Severity of Illness Index, Temporal Lobe, Cohort Studies
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