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Cited by 389

The DOI matches its Crossref record; 334 of the 334 references it cites were found in a registry or an index.

Neuroanatomical substrates of age-related cognitive decline.

Open access
Salthouse, Timothy A.·2011·Psychological Bulletin

Abstract

There are many reports of relations between age and cognitive variables and of relations between age and variables representing different aspects of brain structure and a few reports of relations between brain structure variables and cognitive variables. These findings have sometimes led to inferences that the age-related brain changes cause the age-related cognitive changes. Although this conclusion may well be true, it is widely recognized that simple correlations are not sufficient to warrant causal conclusions, and other types of correlational information, such as mediation and correlations between longitudinal brain changes and longitudinal cognitive changes, also have limitations with respect to causal inferences. These issues are discussed, and the existing results on relations of regional volume, white matter hyperintensities, and diffusion tensor imaging measures of white matter integrity to age and to measures of cognitive functioning are reviewed. It is concluded that at the current time the evidence that these aspects of brain structure are neuroanatomical substrates of age-related cognitive decline is weak. The final section contains several suggestions concerning measurement and methodology that may lead to stronger conclusions in the future.

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Metadata

Authors
Salthouse, T. A.
Venue
Psychological Bulletin
Published
2011
Volume
137
Issue
5
Pages
753-784
ISSN
  • 0033-2909 (ISSN-L)
  • 1939-1455
OpenAlex
W2159519447
Cited by
389
References
334
FWCI
19.50
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Neuroanatomical substrates of age-related cognitive decline. https://app.cochat.ai/papers/10.1037/a0023262
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Salthouse, T. A. (2011). Neuroanatomical substrates of age-related cognitive decline. Psychological Bulletin. https://doi.org/10.1037/a0023262

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