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Cited by 195

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Combining imagination and reason in the treatment of depression: A randomized controlled trial of internet-based cognitive-bias modification and internet-CBT for depression.

Open access
Williams, Alishia D., Blackwell, Simon E., Mackenzie, Anna, Holmes, Emily A., Andrews, Gavin·2013·Journal of Consulting and Clinical Psychology

Abstract

OBJECTIVE: Computerized cognitive-bias modification (CBM) protocols are rapidly evolving in experimental medicine yet might best be combined with Internet-based cognitive behavioral therapy (iCBT). No research to date has evaluated the combined approach in depression. The current randomized controlled trial aimed to evaluate both the independent effects of a CBM protocol targeting imagery and interpretation bias (CBM-I) and the combined effects of CBM-I followed by iCBT. METHOD: Patients diagnosed with a major depressive episode were randomized to an 11-week intervention (1 week/CBM-I + 10 weeks/iCBT; n = 38) that was delivered via the Internet with no face-to-face patient contact or to a wait-list control (WLC; n = 31). RESULTS: Intent-to-treat marginal models using restricted maximum likelihood estimation demonstrated significant reductions in primary measures of depressive symptoms and distress corresponding to medium-large effect sizes (Cohen's d = 0.62-2.40) following CBM-I and the combined (CBM-I + iCBT) intervention. Analyses demonstrated that the change in interpretation bias at least partially mediated the reduction in depression symptoms following CBM-I. Treatment superiority over the WLC was also evident on all outcome measures at both time points (Hedges gs = .59-.98). Significant reductions were also observed following the combined intervention on secondary measures associated with depression: disability, anxiety, and repetitive negative thinking (Cohen's d = 1.51-2.23). Twenty-seven percent of patients evidenced clinically significant change following CBM-I, and this proportion increased to 65% following the combined intervention. CONCLUSIONS: The current study provides encouraging results of the integration of Internet-based technologies into an efficacious and acceptable form of treatment delivery. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

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Metadata

Authors
Williams, A. D., Blackwell, S. E., Mackenzie, A., Holmes, E. A., & Andrews, G.
Venue
Journal of Consulting and Clinical Psychology
Published
2013-10
Volume
81
Issue
5
Pages
793-799
ISSN
  • 0022-006X (ISSN-L)
  • 1939-2117
OpenAlex
W2046371322
Cited by
195
References
19
FWCI
28.51
Type
journal article
Language
en
Open access
hybrid

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Williams, A. D., Blackwell, S. E., Mackenzie, A., Holmes, E. A., & Andrews, G. (2013). Combining imagination and reason in the treatment of depression: A randomized controlled trial of internet-based cognitive-bias modification and internet-CBT for depression. Journal of Consulting and Clinical Psychology. https://doi.org/10.1037/a0033247

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