The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Combining imagination and reason in the treatment of depression: A randomized controlled trial of internet-based cognitive-bias modification and internet-CBT for depression.
Open accessAbstract
OBJECTIVE: Computerized cognitive-bias modification (CBM) protocols are rapidly evolving in experimental medicine yet might best be combined with Internet-based cognitive behavioral therapy (iCBT). No research to date has evaluated the combined approach in depression. The current randomized controlled trial aimed to evaluate both the independent effects of a CBM protocol targeting imagery and interpretation bias (CBM-I) and the combined effects of CBM-I followed by iCBT. METHOD: Patients diagnosed with a major depressive episode were randomized to an 11-week intervention (1 week/CBM-I + 10 weeks/iCBT; n = 38) that was delivered via the Internet with no face-to-face patient contact or to a wait-list control (WLC; n = 31). RESULTS: Intent-to-treat marginal models using restricted maximum likelihood estimation demonstrated significant reductions in primary measures of depressive symptoms and distress corresponding to medium-large effect sizes (Cohen's d = 0.62-2.40) following CBM-I and the combined (CBM-I + iCBT) intervention. Analyses demonstrated that the change in interpretation bias at least partially mediated the reduction in depression symptoms following CBM-I. Treatment superiority over the WLC was also evident on all outcome measures at both time points (Hedges gs = .59-.98). Significant reductions were also observed following the combined intervention on secondary measures associated with depression: disability, anxiety, and repetitive negative thinking (Cohen's d = 1.51-2.23). Twenty-seven percent of patients evidenced clinically significant change following CBM-I, and this proportion increased to 65% following the combined intervention. CONCLUSIONS: The current study provides encouraging results of the integration of Internet-based technologies into an efficacious and acceptable form of treatment delivery. (PsycINFO Database Record (c) 2013 APA, all rights reserved).
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Cites
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Cited by
Mental Imagery: Functional Mechanisms and Clinical Applications
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Digital interventions for the treatment of depression: a meta-analytic review
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Metadata
- Authors
- Williams, A. D., Blackwell, S. E., Mackenzie, A., Holmes, E. A., & Andrews, G.
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2013-10
- Volume
- 81
- Issue
- 5
- Pages
- 793-799
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- OpenAlex
- W2046371322
- Cited by
- 195
- References
- 19
- FWCI
- 28.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
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