Cited by 543Retinal Development and DisordersVisual perception and processing mechanismsPhotoreceptor and optogenetics research

Chemistry of Visual Adaptation in the Rat

DOWLING, JOHN E.·1960·Nature

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Crossref · 10.1038/188114a0

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21 of 21 references verified0 citation errors · 0 not checkable

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  • In contrast to invertebrates, vertebrates evolved a relatively complex sequence of enzymatic reactions to facilitate thermodynamically unfavorable isomerization of retinoid independently of light.

    “In contrast to invertebrates, in which isomerized visual chromophore does not leave the binding pocket and can be re-isomerized back to 11-cis configuration in situ [82,83], vertebrates evolved a relatively complex sequence of enzymatic reactions to facilitate thermodynamically unfavorable isomerization of retinoid independently of light [3,84].”

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Authors
DOWLING, J. E.
Affiliations
Harvard University (US)
Corresponding author
DOWLING, JOHN E.
Venue
Nature
Published
1960-10
Volume
188
Issue
4745
Pages
114-118
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W1992632065
Cited by
543
References
21
Citations by year
2026: 4 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 3 · 2018: 5 · 2017: 4 · 2016: 5 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 5
FWCI
5.21
Type
journal article
Language
en
Open access
closed
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Photoreceptor and optogenetics research
Keywords
visual adaptation, rhodopsin, retinal pigment epithelium, phototransduction, rod photoreceptors, rat retina, light adaptation
MeSH terms
Acclimatization, Adaptation, Ocular, Adaptation, Physiological, Animals, Eye, Head, Rats

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