Synthesis of Complex Organic Compounds from Simple Precursors: Formation of Amino-Acids, Amino-Acid Polymers, Fatty Acids and Purines from Ammonium Cyanide
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Hydrogen cyanide condensation in the presence of ammonia yields purines and purine derivatives.
“Hydrogen cyanide condensation in the presence of ammonia yields purines and purine derivatives (Lowe et al., 1963).”
From The Astrobiology Primer v2.0 (2016) · cites this paper as Lowe et al., 1963
Cites
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Garrison, W. M., Morrison, D. C., Hamilton, J. G., Benson, A. A., & Calvin, M. (1951) · Science · doi:10.1126/science.114.2964.416 · Cited by 173 · see citing works
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Origins of building blocks of life: A review
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Serpentinization, carbon, and deep life
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“Hydrogen cyanide condensation in the presence of ammonia yields purines and purine derivatives (Lowe et al., 1963).”
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- Authors
- LOWE, C. U., REES, M. W., & MARKHAM, R.
- Affiliations
- University at Buffalo, State University of New York (US)
- Venue
- Nature
- Published
- 1963-07
- Volume
- 199
- Issue
- 4890
- Pages
- 219-222
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2086143970
- Cited by
- 208
- References
- 3
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 5 · 2023: 2 · 2022: 4 · 2021: 7 · 2020: 7 · 2019: 2 · 2018: 4 · 2017: 5 · 2016: 8 · 2015: 2 · 2013: 5 · 2012: 2
- FWCI
- 5.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Synthetic Organic Chemistry
- Keywords
- ammonium cyanide, origin of life, amino acid synthesis, amino acid polymers, fatty acids, purines, Miller-Urey experiment, prebiotic chemistry, fatty acid synthesis, purine biosynthesis
- MeSH terms
- Amino Acids, Quaternary Ammonium Compounds, Carbon Isotopes, Chromatography, Cyanides, Electrophoresis, Fatty Acids, Methionine, Polymers, Purines, Research, Ammonium Compounds
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