The DOI matches its Crossref record; 12 of the 13 references it cites were found in a registry or an index.
Polymers for the sustained release of proteins and other macromolecules
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Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The rate of release can be governed through polymer modification, the development of new polymers, or the synthesis of copolymers.233–235”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [235]
In the citing paper
“initial work done by Langer and Folkman 70 , which showed that macromolecules such as proteins could be encapsulated in small polymer-based carriers”
From Nanotechnology approaches for global infectious diseases (2021) · cites this paper as [70]
Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
A modified uronic acid carbazole reaction
Bitter, T., & Muir, H. M. (1962) · Analytical Biochemistry · doi:10.1016/0003-2697(62)90095-7 · Cited by 6,259
Critical Variables in the Radioimmunoassay of Serum Insulin Using the Double Antibody Technic
Soeldner, J. S., & Slone, D. (1965) · Diabetes · doi:10.2337/diab.14.12.771 · Cited by 714
Proceedings: Tumor angiogenesis factor.
Folkman, J. (1974) · PubMed · Cited by 460
Self-citationThe use of silicone rubber as a carrier for prolonged drug therapy
Folkman, J., & Long, D. M. (1964) · Journal of Surgical Research · doi:10.1016/s0022-4804(64)80040-8 · Cited by 368
Self-citationFromer, C., & Klintworth, G. K. (1975) · PubMed · Cited by 119
Radial diffusion in gel for micro determination of enzymes
Schumacher, G., & Schill, W. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90165-0 · Cited by 113
Diffusion in Polymer Gel Implants
Davis, B. K. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.8.3120 · Cited by 112
Radial diffusion in gel for micro determination of enzymes
Schill, W., & Schumacher, G. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90324-7 · Cited by 94
Control of diabetes with polyacrylamide implants containing insulin
Davis, B. K. (1972) · Cellular and Molecular Life Sciences · doi:10.1007/bf01928732 · Cited by 72
Flagged first, then by citations
1 of the 13 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Gimbrone, M. A., Jr, Cotran, R. S., Leapman, S. B., and Folkman, J., J. natn. Cancer Inst., 42, 314–427 (1974).
- Fromer, C. H., and Klintworth, G. K., Am. J. Path., 79, 537–554 (1975).
- Folkman, J., Cancer Res., 34, 2109–2113 (1974).
Cited by
Sorted by citations
Cancer nanomedicine: progress, challenges and opportunities
Shi, J., Kantoff, P. W., Wooster, R., & Farokhzad, O. C. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2016.108 · Cited by 5,873
Lipid nanoparticles for mRNA delivery
Hou, X., Zaks, T., Langer, R., & Dong, Y. (2021) · Nature Reviews Materials · doi:10.1038/s41578-021-00358-0 · Cited by 4,076
Self-citationFolkman, J., & Klagsbrun, M. (1987) · Science · doi:10.1126/science.2432664 · Cited by 3,491
Self-citationImpact of Nanotechnology on Drug Delivery
Farokhzad, O. C., & Langer, R. (2009) · ACS Nano · doi:10.1021/nn900002m · Cited by 3,443
Self-citationKamaly, N., Yameen, B., Wu, J., & Farokhzad, O. C. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00346 · Cited by 3,070
Metadata
- Authors
- LANGER, R., & FOLKMAN, J.
- Affiliations
- Boston Children's Hospital (US)
- Venue
- Nature
- Published
- 1976-10-28
- Volume
- 263
- Issue
- 5580
- Pages
- 797-800
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2052580681
- Cited by
- 1,182
- References
- 13
- Citations by year
- 2026: 23 · 2025: 33 · 2024: 37 · 2023: 47 · 2022: 44 · 2021: 68 · 2020: 35 · 2019: 28 · 2018: 47 · 2017: 30 · 2016: 32 · 2015: 25 · 2014: 41 · 2013: 33 · 2012: 31
- FWCI
- 7.81
- Type
- journal article
- Language
- en
- Update notices
- correction (1976-11-18)
- Open access
- closed
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- sustained drug release, protein delivery, macromolecule delivery, biodegradable polymers, silicone rubber, controlled drug release
- MeSH terms
- Alkaline Phosphatase, Animals, Catalase, Delayed-Action Preparations, Inflammation, Molecular Weight, Muramidase, Polymers, Rabbits, Structure-Activity Relationship, Trypsin Inhibitors, Angiogenesis Inducing Agents
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