The DOI matches its Crossref record; 12 of the 13 references it cites were found in a registry or an index.
Polymers for the sustained release of proteins and other macromolecules
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The rate of release can be governed through polymer modification, the development of new polymers, or the synthesis of copolymers.233–235”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [235]
In the citing paper
“initial work done by Langer and Folkman 70 , which showed that macromolecules such as proteins could be encapsulated in small polymer-based carriers”
From Nanotechnology approaches for global infectious diseases (2021) · cites this paper as [70]
Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
A modified uronic acid carbazole reaction
Bitter, T., & Muir, H. M. (1962) · Analytical Biochemistry · doi:10.1016/0003-2697(62)90095-7 · Cited by 6,259
Critical Variables in the Radioimmunoassay of Serum Insulin Using the Double Antibody Technic
Soeldner, J. S., & Slone, D. (1965) · Diabetes · doi:10.2337/diab.14.12.771 · Cited by 714
Proceedings: Tumor angiogenesis factor.
Folkman, J. (1974) · PubMed · Cited by 460
Self-citationThe use of silicone rubber as a carrier for prolonged drug therapy
Folkman, J., & Long, D. M. (1964) · Journal of Surgical Research · doi:10.1016/s0022-4804(64)80040-8 · Cited by 368
Self-citationFromer, C., & Klintworth, G. K. (1975) · PubMed · Cited by 119
Radial diffusion in gel for micro determination of enzymes
Schumacher, G., & Schill, W. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90165-0 · Cited by 113
Diffusion in Polymer Gel Implants
Davis, B. K. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.8.3120 · Cited by 112
Radial diffusion in gel for micro determination of enzymes
Schill, W., & Schumacher, G. (1972) · Analytical Biochemistry · doi:10.1016/0003-2697(72)90324-7 · Cited by 94
Control of diabetes with polyacrylamide implants containing insulin
Davis, B. K. (1972) · Cellular and Molecular Life Sciences · doi:10.1007/bf01928732 · Cited by 72
Flagged first, then by citations
1 of the 13 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Gimbrone, M. A., Jr, Cotran, R. S., Leapman, S. B., and Folkman, J., J. natn. Cancer Inst., 42, 314–427 (1974).
- Fromer, C. H., and Klintworth, G. K., Am. J. Path., 79, 537–554 (1975).
- Folkman, J., Cancer Res., 34, 2109–2113 (1974).
Cited by
Sorted by citations
Cancer nanomedicine: progress, challenges and opportunities
Shi, J., Kantoff, P. W., Wooster, R., & Farokhzad, O. C. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2016.108 · Cited by 5,873
Lipid nanoparticles for mRNA delivery
Hou, X., Zaks, T., Langer, R., & Dong, Y. (2021) · Nature Reviews Materials · doi:10.1038/s41578-021-00358-0 · Cited by 4,076
Self-citationFolkman, J., & Klagsbrun, M. (1987) · Science · doi:10.1126/science.2432664 · Cited by 3,491
Self-citationImpact of Nanotechnology on Drug Delivery
Farokhzad, O. C., & Langer, R. (2009) · ACS Nano · doi:10.1021/nn900002m · Cited by 3,443
Self-citationKamaly, N., Yameen, B., Wu, J., & Farokhzad, O. C. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00346 · Cited by 3,070
Angiogenesis: an organizing principle for drug discovery?
Folkman, J. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2115 · Cited by 2,299
Self-citationAdvanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy
Pérez‐Herrero, E., & Fernández‐Medarde, A. (2015) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2015.03.018 · Cited by 1,936
Huh, A. J., & Kwon, Y. J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.07.002 · Cited by 1,920
Langer, R. (1990) · Science · doi:10.1126/science.2218494 · Cited by 1,778
Self-citationTargeted polymeric therapeutic nanoparticles: design, development and clinical translation
Kamaly, N., Xiao, Z., Valencia, P. M., Radovic‐Moreno, A. F., & Farokhzad, O. C. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15344k · Cited by 1,774
Overcoming the challenges in administering biopharmaceuticals: Formulation and delivery strategies
Mitragotri, S., Burke, P. A., & Langer, R. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4363 · Cited by 1,702
Self-citationLü, Y., Aimetti, A. A., Langer, R., & Gu, Z. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2016.75 · Cited by 1,448
Self-citationKenawy, E., Bowlin, G. L., Mansfield, K. F., Layman, J. M., Simpson, D. G., Sanders, E. H., & Wnek, G. E. (2002) · Journal of Controlled Release · doi:10.1016/s0168-3659(02)00041-x · Cited by 1,312
Danhier, F. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.11.015 · Cited by 1,288
Folkman, J. (1985) · Advances in cancer research · doi:10.1016/s0065-230x(08)60946-x · Cited by 1,068
Self-citationEmerging Frontiers in Drug Delivery
Tibbitt, M. W., Dahlman, J. E., & Langer, R. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.5b09974 · Cited by 1,009
Self-citationIsolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells
Fett, J. W., Strydom, D. J., Lobb, R. R., Alderman, E. M., Bethune, J. L., Riordan, J. F., & Vallée, B. L. (1985) · Biochemistry · doi:10.1021/bi00341a030 · Cited by 923
Development of Nanoparticles for Antimicrobial Drug Delivery
Zhang, L., Pornpattananangkul, D., Hu, C.-M., & Huang, C.-W. (2010) · Current Medicinal Chemistry · doi:10.2174/092986710790416290 · Cited by 904
Advances in Biomaterials for Drug Delivery
Fenton, O. S., Olafson, K. N., Pillai, P. S., Mitchell, M. J., & Langer, R. (2018) · Advanced Materials · doi:10.1002/adma.201705328 · Cited by 890
Self-citationControlled Delivery Systems for Proteins Based on Poly(Lactic/Glycolic Acid) Microspheres
Cohen, S., Yoshioka, T., Lucarelli, M., Hwang, L. H., & Langer, R. (1991) · Pharmaceutical Research · doi:10.1023/a:1015841715384 · Cited by 849
Self-citationTemperature-responsive gels and thermogelling polymer matrices for protein and peptide delivery
Bromberg, L. E. (1998) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00121-x · Cited by 848
Drug delivery by supramolecular design
Webber, M. J., & Langer, R. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00391a · Cited by 828
Self-citationActivated macrophages induce vascular proliferation
Polverini, P. J., Cotran, R. S., Gimbrone, M. A., & Unanue, E. R. (1977) · Nature · doi:10.1038/269804a0 · Cited by 805
Preparation of microspheres by the solvent evaporation technique
O’Donnell, P. B., & McGinity, J. W. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00049-5 · Cited by 826
Nanomedicine: Developing smarter therapeutic and diagnostic modalities☆
Farokhzad, O. C., & Langer, R. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.09.011 · Cited by 802
Self-citationBiomaterials in Drug Delivery and Tissue Engineering: One Laboratory's Experience
Langer, R. (1999) · Accounts of Chemical Research · doi:10.1021/ar9800993 · Cited by 756
Self-citationThe origins and evolution of “controlled” drug delivery systems
Hoffman, A. S. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.08.012 · Cited by 740
Griffith, L. G. (2000) · Acta Materialia · doi:10.1016/s1359-6454(99)00299-2 · Cited by 746
Folkman, J. (1986) · PubMed · Cited by 732
Self-citationInhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides
Maione, T. E., Gray, G. S., Petro, J., Hunt, A. J., Donner, A. L., Bauer, S., Carson, H. F., & Sharpe, R. J. (1990) · Science · doi:10.1126/science.1688470 · Cited by 698
Oxygen Tension Regulates the Expression of Angiogenesis Factor by Macrophages
Knighton, D. R., Hunt, T. K., Scheuenstuhl, H., Halliday, B. J., Werb, Z., & Banda, M. J. (1983) · Science · doi:10.1126/science.6612342 · Cited by 685
Present and future applications of biomaterials in controlled drug delivery systems
Langer, R., & Peppas, N. A. (1981) · Biomaterials · doi:10.1016/0142-9612(81)90059-4 · Cited by 657
Self-citationNanoparticles of Metal‐Organic Frameworks: On the Road to In Vivo Efficacy in Biomedicine
Simón‐Yarza, T., Mielcarek, A., Couvreur, P., & Serre, C. (2018) · Advanced Materials · doi:10.1002/adma.201707365 · Cited by 661
Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles
Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645
Folkman, J., Langer, R., Linhardt, R. J., Haudenschild, C. C., & Taylor, S. (1983) · Science · doi:10.1126/science.6192498 · Cited by 619
Self-citationInorganic nanoparticles for cancer imaging and therapy
Huang, H., Barua, S., Sharma, G., Dey, S. K., & Rege, K. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.06.004 · Cited by 642
Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide)
Zhu, G., Mallery, S. R., & Schwendeman, S. P. (2000) · Nature Biotechnology · doi:10.1038/71916 · Cited by 621
Selective cell transplantation using bioabsorbable artificial polymers as matrices
Vacanti, J. P., Morse, M. A., Saltzman, W. M., Domb, A. J., Pérez‐Atayde, A. R., & Langer, R. (1988) · Journal of Pediatric Surgery · doi:10.1016/s0022-3468(88)80529-3 · Cited by 613
Self-citationProtamine is an inhibitor of angiogenesis
Taylor, S., & Folkman, J. (1982) · Nature · doi:10.1038/297307a0 · Cited by 580
Self-citationBiodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors
Gagliardi, A., Giuliano, E., Eeda, V., Fresta, M., Bulotta, S., Awasthi, V., & Cosco, D. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.601626 · Cited by 616
Bessa, P. C., Casal, M., & Reis, R. L. (2008) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.74 · Cited by 553
PLGA-Based Nanoparticles as Cancer Drug Delivery Systems
Mirakabad, F. S. T., Nejati‐Koshki, K., Akbarzadeh, A., Yamchi, M. R., Milani, M., Zarghami, N., Zeighamian, V., Rahimzadeh, A., Alimohammadi, S., Hanifehpour, Y., et al. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.2.517 · Cited by 553
An overview of clinical and commercial impact of drug delivery systems
Anselmo, A. C., & Mitragotri, S. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.03.053 · Cited by 525
Nanotechnology approaches for global infectious diseases
Kirtane, A. R., Verma, M., Karandikar, P., Furin, J., Langer, R., & Traverso, G. (2021) · Nature Nanotechnology · doi:10.1038/s41565-021-00866-8 · Cited by 520
Self-citationTargeted nanoparticles for cancer therapy
Gu, F., Karnik, R., Wang, A. Z., Alexis, F., Levy‐Nissenbaum, E., Hong, S., Langer, R., & Farokhzad, O. C. (2007) · Nano Today · doi:10.1016/s1748-0132(07)70083-x · Cited by 520
Self-citationThe landscape of mRNA nanomedicine
Huang, X., Kong, N., Zhang, X., Cao, Y., Langer, R., & Tao, W. (2022) · Nature Medicine · doi:10.1038/s41591-022-02061-1 · Cited by 511
Self-citationOvercoming barriers to patient adherence: the case for developing innovative drug delivery systems
Baryakova, T. H., Pogostin, B. H., Langer, R., & McHugh, K. J. (2023) · Nature Reviews Drug Discovery · doi:10.1038/s41573-023-00670-0 · Cited by 566
Self-citationTargeted therapy using nanotechnology: focus on cancer
Sechi, M., Sanna, V., & Pala, N. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s36654 · Cited by 509
mRNA-based cancer therapeutics
Liu, C., Shi, Q., Huang, X., Koo, S., Kong, N., & Tao, W. (2023) · Nature Reviews Cancer · doi:10.1038/s41568-023-00586-2 · Cited by 500
Jiang, W., Rk, G., DESHPANDE, M., & Schwendeman, S. P. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2004.09.003 · Cited by 480
Photoswitchable Nanoparticles for Triggered Tissue Penetration and Drug Delivery
Tong, R., Hemmati, H. D., Langer, R., & Kohane, D. S. (2012) · Journal of the American Chemical Society · doi:10.1021/ja211888a · Cited by 478
Self-citationSelf-Assembled Targeted Nanoparticles: Evolution of Technologies and Bench to Bedside Translation
Shi, J., Xiao, Z., Kamaly, N., & Farokhzad, O. C. (2011) · Accounts of Chemical Research · doi:10.1021/ar200054n · Cited by 489
Angiogenesis and vasculogenesis in pregnancy
Zygmunt, M., Herr, F., Münstedt, K., Lang, U., & Liang, O. D. (2003) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(03)00168-4 · Cited by 473
Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents
Dinarvand, R., Sepehri, N., Manouchehri, Rouhani, & Atyabi, F. (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s18905 · Cited by 468
Hydrogel-based devices for biomedical applications
Deligkaris, K., Tadele, T. S., Olthuis, W., & van den Berg, A. (2010) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2010.03.083 · Cited by 453
Breakthrough treatments for accelerated wound healing
Freedman, B. R., Hwang, C. D., Talbot, S. G., Hibler, B. P., Matoori, S., & Mooney, D. J. (2023) · Science Advances · doi:10.1126/sciadv.ade7007 · Cited by 468
Microfluidic formulation of nanoparticles for biomedical applications
Shepherd, S. J., Issadore, D., & Mitchell, M. J. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120826 · Cited by 465
Langer, R., & Peppas, N. A. (1983) · Journal of macromolecular science. Part C, Reviews in macromolecular chemistry and physics/Journal of macromolecular science. Reviews in macromolecular chemistry and physics · doi:10.1080/07366578308079439 · Cited by 449
Self-citationDrug delivery to the central nervous system
Nance, E. A., Pun, S. H., Saigal, R., & Sellers, D. L. (2021) · Nature Reviews Materials · doi:10.1038/s41578-021-00394-w · Cited by 442
Cancer drug delivery in the nano era: An overview and perspectives
Li, Z., Tan, S., Li, S., Shen, Q., & Wang, K. (2017) · Oncology Reports · doi:10.3892/or.2017.5718 · Cited by 417
Targeting dendritic cells with biomaterials: developing the next generation of vaccines
Reddy, S. T., Swartz, M. A., & Hubbell, J. A. (2006) · Trends in Immunology · doi:10.1016/j.it.2006.10.005 · Cited by 406
A model of angiogenesis in the mouse cornea.
Kenyon, B. M., Voest, E. E., Chen, C. C., Flynn, E. A., Folkman, J., & D’Amato, R. J. (1996) · PubMed · Cited by 403
Self-citationEvolving Drug Delivery Strategies to Overcome the Blood Brain Barrier
S. Hersh, D., S. Wadajkar, A., B. Roberts, N., G. Perez, J., P. Connolly, N., Frenkel, V., A. Winkles, J., F. Woodworth, G., & J. Kim, A. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666151221150733 · Cited by 387
Taşaltın, N., Nnamchi, P. S., & Saud, S. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.87879 · Cited by 432
Interleukin-8. A corneal factor that induces neovascularization.
Strieter, R. M., Kunkel, S. L., Elner, V. M., Mártonyi, C. L., Koch, A. E., Polverini, P. J., & Elner, V. M. (1992) · PubMed Central · Cited by 383
Vasculogenesis and Angiogenesis as Mechanisms of Vascular Network Formation, Growth and Remodeling
Patan, S. (2000) · Journal of Neuro-Oncology · doi:10.1023/a:1006493130855 · Cited by 397
Nanoparticle Technologies for Cancer Therapy
Alexis, F., Pridgen, E. M., Langer, R., & Farokhzad, O. C. (2009) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-00477-3_2 · Cited by 384
Self-citationFeinberg, R. N., & Beebe, D. C. (1983) · Science · doi:10.1126/science.6857242 · Cited by 371
Song, C., Labhasetwar, V. D., Murphy, H. S., Qu, X., Humphrey, W. R., Shebuski, R. J., & Levy, R. J. (1997) · Journal of Controlled Release · doi:10.1016/s0168-3659(96)01484-8 · Cited by 370
Zhong, R., Talebian, S., Mendes, B. B., Wallace, G. G., Langer, R., Conde, J., & Shi, J. (2023) · Nature Materials · doi:10.1038/s41563-023-01472-w · Cited by 391
Self-citationNew frontiers in nanotechnology for cancer treatment
Alexis, F., Rhee, J., Richie, J. P., Radovic‐Moreno, A. F., Langer, R., & Farokhzad, O. C. (2008) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2007.03.017 · Cited by 361
Self-citationElaborations on the Higuchi model for drug delivery
Paul, D. R. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.10.037 · Cited by 355
Drug delivery systems for programmed and on-demand release
Davoodi, P., Lee, L. Y., Xu, Q., Sunil, V., Sun, Y., Soh, S., & Wang, C. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.07.002 · Cited by 372
Advancing the field of drug delivery
Moses, M. A., Brem, H., & Langer, R. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00276-9 · Cited by 344
Self-citationBawarski, W. E., Chidlowsky, E., Bharali, D. J., & Mousa, S. A. (2008) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2008.06.002 · Cited by 342
Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion
Lieberman, D. M., Laske, D. W., Morrison, P. F., Bankiewicz, K. S., & Oldfield, E. H. (1995) · Journal of neurosurgery · doi:10.3171/jns.1995.82.6.1021 · Cited by 338
PLGA-based nanoparticles: A new paradigm in biomedical applications
Sharma, S., Parmar, A., Kori, S., & Sandhir, R. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2015.06.014 · Cited by 350
Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions
Berkland, C. J., Kim, K., & Pack, D. W. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00289-9 · Cited by 337
Nucleic acid delivery for therapeutic applications
Gupta, A., Andresen, J. L., Manan, R. S., & Langer, R. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113834 · Cited by 351
Self-citationLocalized delivery of growth factors for bone repair
Luginbuehl, V., Meinel, L., Merkle, H. P., & Gander, B. A. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.03.004 · Cited by 336
Effects of protein dose and delivery system on BMP-mediated bone regeneration
Boerckel, J. D., Kolambkar, Y. M., Dupont, K. M., Uhrig, B. A., Phelps, E. A., Stevens, H. Y., Garcı́a, A. J., & Guldberg, R. E. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.03.063 · Cited by 325
Polymeric microneedles for transdermal protein delivery
Ye, Y., Yu, J., Wen, D., Kahkoska, A. R., & Gu, Z. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.01.015 · Cited by 331
Targeting angiogenesis in oncology, ophthalmology and beyond
Cao, Y., Langer, R., & Ferrara, N. (2023) · Nature Reviews Drug Discovery · doi:10.1038/s41573-023-00671-z · Cited by 339
Self-citationHigh-flow microinfusion: tissue penetration and pharmacodynamics
Morrison, P. F., Laske, D. W., Bobo, H., Oldfield, E. H., & Dedrick, R. L. (1994) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1994.266.1.r292 · Cited by 327
Progress, challenges, and future of nanomedicine
Zhang, C., Yan, L., Wang, X., Zhu, S., Chen, C., Gu, Z., & Zhao, Y. (2020) · Nano Today · doi:10.1016/j.nantod.2020.101008 · Cited by 331
Materials and methods for delivery of biological drugs
Zelikin, A. N., Ehrhardt, C., & Healy, A. M. (2016) · Nature Chemistry · doi:10.1038/nchem.2629 · Cited by 321
Anticancer Polymeric Nanomedicines
Tong, R., & Cheng, J. (2007) · Journal of macromolecular science. Part C, Reviews in macromolecular chemistry and physics/Journal of macromolecular science. Reviews in macromolecular chemistry and physics · doi:10.1080/15583720701455079 · Cited by 313
Chai, Y. C., Carlier, A., Bolander, J., Roberts, S. J., Geris, L., Schrooten, J., Oosterwyck, H. V., & Luyten, F. P. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.07.002 · Cited by 305
pH-Responsive Polymer Nanomaterials for Tumor Therapy
Chu, S., Shi, X., Tian, Y., & Gao, F. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.855019 · Cited by 321
Macroscale delivery systems for molecular and cellular payloads
Kearney, C. J., & Mooney, D. J. (2013) · Nature Materials · doi:10.1038/nmat3758 · Cited by 302
Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity
Freedman, B. R., Kuttler, A., Beckmann, N., Nam, S., Kent, D., Schuleit, M., Ramazani, F., Accart, N., Rock, A., Li, J., et al. (2022) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00810-0 · Cited by 310
Basic fibroblast growth factor induces retinal regeneration in vivo
Park, C. M., & Hollenberg, M. J. (1989) · Developmental Biology · doi:10.1016/0012-1606(89)90089-4 · Cited by 295
Control of Angiogenesis with Synthetic Heparin Substitutes
Folkman, J., Weisz, P. B., Joullié, M. M., Li, W. W., & Ewing, W. R. (1989) · Science · doi:10.1126/science.2467380 · Cited by 289
Self-citationEvolution and clinical translation of drug delivery nanomaterials
Hassan, S., Prakash, G., Bal‐Öztürk, A., Saghazadeh, S., Sohail, M. F., Seo, J., Dokmeci, M. R., Zhang, Y. S., & Khademhosseini, A. (2017) · Nano Today · doi:10.1016/j.nantod.2017.06.008 · Cited by 291
INVITED REVIEW POLYMERIC DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE
Langer, R. (1980) · Chemical Engineering Communications · doi:10.1080/00986448008912519 · Cited by 288
Self-citationKawai, K., Suzuki, S., Tabata, Y., Ikada, Y., & Nishimura, Y. (2000) · Biomaterials · doi:10.1016/s0142-9612(99)00207-0 · Cited by 285
Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imaging
Jung, H. N., Lee, S.-Y., Lee, S., Youn, H., & Im, H.-J. (2022) · Theranostics · doi:10.7150/thno.77259 · Cited by 282
Engineering and physical sciences in oncology: challenges and opportunities
Mitchell, M. J., Jain, R. K., & Langer, R. (2017) · Nature Reviews Cancer · doi:10.1038/nrc.2017.83 · Cited by 273
Self-citationBiofunctionalized targeted nanoparticles for therapeutic applications
Wang, A. Z., Gu, F., Zhang, L., Chan, J. M., Radovic-Moreno, A., Shaikh, M. R., & Farokhzad, O. C. (2008) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.8.8.1063 · Cited by 277
Folkman, J., & Ingber, D. E. (1987) · Annals of Surgery · doi:10.1097/00000658-198709000-00016 · Cited by 276
Self-citation
Metadata
- Authors
- LANGER, R., & FOLKMAN, J.
- Affiliations
- Boston Children's Hospital (US)
- Venue
- Nature
- Published
- 1976-10-28
- Volume
- 263
- Issue
- 5580
- Pages
- 797-800
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2052580681
- Cited by
- 1,182
- References
- 13
- Citations by year
- 2026: 23 · 2025: 33 · 2024: 37 · 2023: 47 · 2022: 44 · 2021: 68 · 2020: 35 · 2019: 28 · 2018: 47 · 2017: 30 · 2016: 32 · 2015: 25 · 2014: 41 · 2013: 33 · 2012: 31
- FWCI
- 7.81
- Type
- journal article
- Language
- en
- Update notices
- correction (1976-11-18)
- Open access
- closed
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- sustained drug release, protein delivery, macromolecule delivery, biodegradable polymers, silicone rubber, controlled drug release
- MeSH terms
- Alkaline Phosphatase, Animals, Catalase, Delayed-Action Preparations, Inflammation, Molecular Weight, Muramidase, Polymers, Rabbits, Structure-Activity Relationship, Trypsin Inhibitors, Angiogenesis Inducing Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review