CoChat
Sign Up
Cited by 3,491

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Angiogenic factors.

Folkman, Judah, Klagsbrun, Michael·1987·Science
DOI 10.1126/science.2432664
Open this paper in CoChat — free account

Abstract

Within the past 2 years, several angiogenic factors have been fully purified, their amino acid sequences determined, and their genes cloned. These polypeptides include acidic and basic fibroblast growth factor, angiogenin, and transforming growth factors α and β. Other less well characterized angiogenesis factors have also been isolated, some of which are lipids. This article traces the discovery of the angiogenic factors and describes their possible significance in understanding growth regulation of the vascular system. When evaluated according to their putative targets, they appear to fall into two groups: (i) those that act directly on vascular endothelial cells to stimulate locomotion or mitosis, and (ii) those that act indirectly by mobilizing host cells (for example, macrophages) to release endothelial growth factors. In addition to their presence in tumors undergoing neovascularization, the same angiogenic peptides are found in many normal tissues where neovascularization is not occurring. This suggests that physiological expression of angiogenic factors is tightly regulated. In addition to the persistent angiogenesis induced by tumors, it now appears that a variety of nonneoplastic diseases, previously thought to be unrelated, can be considered as "angiogenic diseases" because they are dominated by the pathologic growth of capillary blood vessels.

Overview

Integrity signals

Registry

Crossref · 10.1126/science.2432664

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • An increase of angiogenic regulators is expected to broadly contribute to improved vascularization and, through increased tissue perfusion, to tissue repair.

    “an increase of angiogenic regulators is expected to broadly contribute to improved vascularization [73, 74] and through this increased perfusion of tissues, to tissue repair.”

    From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [73]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 142

  1. 10.1126/science.2425435 · DOI
  2. ALGIRE, G.H., VASCULAR REACTIONS OF NORMAL AND MALIGNANT TISSUES INVIVO .2. THE VASCULAR REACTION OF NORMAL AND NEOPLASTIC TISSUES OF MICE TO A BACTERIAL POLYSACCHARIDE FROM SERRATIA MARCESCENS (BACILLUS PRODIGIOSUS) CULTURE FILTRATES, JOURNAL OF THE NATIONAL CANCER INSTITUTE 8: 53 (1947).
  3. ASSOIAN, R.K., TRANSFORMING GROWTH FACTOR-BETA IN HUMAN-PLATELETS - IDENTIFICATION OF A MAJOR STORAGE SITE, PURIFICATION, AND CHARACTERIZATION, JOURNAL OF BIOLOGICAL CHEMISTRY 258: 7155 (1983). · DOI
  4. AUSPRUNK, D.H., DIFFERENTIATION OF VASCULAR ENDOTHELIUM IN CHICK CHORIOALLANTOIS - STRUCTURAL AND AUTORADIOGRAPHIC STUDY, DEVELOPMENTAL BIOLOGY 38: 237 (1974). · DOI
  5. AUSPRUNK, D.H., MIGRATION AND PROLIFERATION OF ENDOTHELIAL CELLS IN PREFORMED AND NEWLY FORMED BLOOD-VESSELS DURING TUMOR ANGIOGENESIS, MICROVASCULAR RESEARCH 14: 53 (1977). · DOI
  6. AZIZKHAN, R.G., MAST-CELL HEPARIN STIMULATES MIGRATION OF CAPILLARY ENDOTHELIAL-CELLS INVITRO, JOURNAL OF EXPERIMENTAL MEDICINE 152: 931 (1980). · DOI
  7. BAIRD, A, INHIBITION OF ENDOTHELIAL-CELL PROLIFERATION BY TYPE BETA-TRANSFORMING GROWTH-FACTOR - INTERACTIONS WITH ACIDIC AND BASIC FIBROBLAST GROWTH-FACTORS, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 138: 476 (1986). · DOI
  8. BAIRD, A, IMMUNOREACTIVE FIBROBLAST GROWTH-FACTOR IN CELLS OF PERITONEAL-EXUDATE SUGGESTS ITS IDENTITY WITH MACROPHAGE-DERIVED GROWTH-FACTOR, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 126: 358 (1985). · DOI
  9. BAIRD, A, MOLECULAR CHARACTERIZATION OF FIBROBLAST GROWTH-FACTOR - DISTRIBUTION AND BIOLOGICAL-ACTIVITIES IN VARIOUS TISSUES, RECENT PROGRESS IN HORMONE RESEARCH 42: 143 (1986).
  10. BAIRD, A, ISOLATION AND PARTIAL CHARACTERIZATION OF AN ENDOTHELIAL-CELL GROWTH-FACTOR FROM THE BOVINE KIDNEY - HOMOLOGY WITH BASIC FIBROBLAST GROWTH-FACTOR, REGULATORY PEPTIDES 12: 201 (1985). · DOI
  11. BANDA, M.J., ISOLATION OF A NONMITOGENIC ANGIOGENESIS FACTOR FROM WOUND FLUID, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79: 7773 (1982).
  12. BARGER, A.C., HYPOTHESIS - VASA VASORUM AND NEOVASCULARIZATION OF HUMAN CORONARY-ARTERIES - A POSSIBLE ROLE IN THE PATHO-PHYSIOLOGY OF ATHEROSCLEROSIS, NEW ENGLAND JOURNAL OF MEDICINE 310: 175 (1984). · DOI
  13. BARRITAULT, D, IS THERE A UBIQUITOUS GROWTH-FACTOR IN THE EYE - PROLIFERATION INDUCED IN DIFFERENT CELL-TYPES BY EYE-DERIVED GROWTH-FACTORS, DIFFERENTIATION 18: 29 (1981). · DOI
  14. BENEZRA, D, NEO-VASCULOGENIC ABILITY OF PROSTAGLANDINS, GROWTH-FACTORS, AND SYNTHETIC CHEMOATTRACTANTS, AMERICAN JOURNAL OF OPHTHALMOLOGY 86: 455 (1978). · DOI
  15. BIRDWELL, C.R., FACTORS FROM 3T3-CELLS STIMULATE PROLIFERATION OF CULTURED VASCULAR ENDOTHELIAL CELLS, NATURE 268: 528 (1977). · DOI
  16. BOHLEN, P, ISOLATION AND PARTIAL MOLECULAR CHARACTERIZATION OF PITUITARY FIBROBLAST GROWTH-FACTOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 5364 (1984).
  17. BURGESS, W.H., MULTIPLE FORMS OF ENDOTHELIAL-CELL GROWTH-FACTOR - RAPID ISOLATION AND BIOLOGICAL AND CHEMICAL CHARACTERIZATION, JOURNAL OF BIOLOGICAL CHEMISTRY 260: 1389 (1985).
  18. BURGESS, W.H., STRUCTURAL EVIDENCE THAT ENDOTHELIAL-CELL GROWTH-FACTOR-BETA IS THE PRECURSOR OF BOTH ENDOTHELIAL-CELL GROWTH FACTOR-ALPHA AND ACIDIC FIBROBLAST GROWTH-FACTOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 7216 (1986).
  19. CHILDS, C.B., SERUM CONTAINS A PLATELET-DERIVED TRANSFORMING GROWTH-FACTOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79: 5312 (1982).
  20. CLARK, E.R., Observations on changes in blood vascular endothelium in the living animal, AMERICAN JOURNAL OF ANATOMY 57: 385 (1935). · DOI
  21. CLARK, E.R., Observations on living preformed blood vessels as seen in a transparent chamber inserted into the rabbit's ear, AMERICAN JOURNAL OF ANATOMY 49: 441 (1932). · DOI
  22. CONN, G, THE ISOLATION AND PURIFICATION OF 2 ANIONIC ENDOTHELIAL CELL-GROWTH FACTORS FROM HUMAN-BRAIN, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 124: 262 (1984). · DOI
  23. COURTY, J, BOVINE RETINA CONTAINS 3 GROWTH-FACTOR ACTIVITIES WITH DIFFERENT AFFINITY TO HEPARIN - EYE DERIVED GROWTH FACTOR-I, FACTOR-II, FACTOR-III, BIOCHIMIE 67: 265 (1985). · DOI
  24. 10.1126/science.2416056 · DOI
  25. DAMORE, P.A., ENDOTHELIAL-CELL MITOGENS DERIVED FROM RETINA AND HYPOTHALAMUS - BIOCHEMICAL AND BIOLOGICAL SIMILARITIES, JOURNAL OF CELL BIOLOGY 99: 1545 (1984). · DOI
  26. DAMORE, P.A., ANGIOGENIC ACTIVITY FROM BOVINE RETINA - PARTIAL-PURIFICATION AND CHARACTERIZATION, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78: 3068 (1981).
  27. DAVIDSON, J.M., ACCELERATED WOUND REPAIR, CELL-PROLIFERATION, AND COLLAGEN ACCUMULATION ARE PRODUCED BY A CARTILAGE-DERIVED GROWTH-FACTOR, JOURNAL OF CELL BIOLOGY 100: 1219 (1985). · DOI
  28. DELARCO, J.E., SARCOMA GROWTH-FACTOR (SGF) - SPECIFIC BINDING TO EPIDERMAL GROWTH-FACTOR (EGF) MEMBRANE-RECEPTORS, JOURNAL OF CELLULAR PHYSIOLOGY 102: 267 (1980). · DOI
  29. DENEKAMP, J, PROGR APPLIED MICROC 42: 28 (1984).
  30. DERYNCK, R, HUMAN TRANSFORMING GROWTH FACTOR-BETA COMPLEMENTARY-DNA SEQUENCE AND EXPRESSION IN NORMAL AND TRANSFORMED-CELLS, NATURE 316: 701 (1985). · DOI
  31. DICORLETO, P.E., CULTURED ENDOTHELIAL-CELLS PRODUCE A PLATELET-DERIVED GROWTH FACTOR-LIKE PROTEIN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80: 1919 (1983).
  32. DOBSON, D.E., J CELL BIOL 101: A109 (1985).
  33. DVORAK, H.F., J NATL CANCER I 62: 1479 (1979).
  34. EHRMANN, R.L., CHORIOCARCINOMA - TRANSFILTER STIMULATION OF VASOPROLIFERATION IN HAMSTER CHEEK POUCH STUDIED BY LIGHT AND ELECTRON MICROSCOPY, JOURNAL OF THE NATIONAL CANCER INSTITUTE 41: 1329 (1968).
  35. EISENSTEIN, R, RESISTANCE OF CERTAIN TISSUES TO INVASION - PENETRABILITY OF EXPLANTED TISSUES BY VASCULARIZED MESENCHYME, AMERICAN JOURNAL OF PATHOLOGY 73: 765 (1973).
  36. ESCH, F, PRIMARY STRUCTURE OF BOVINE BRAIN ACIDIC FIBROBLAST GROWTH-FACTOR (FGF), BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 133: 554 (1985). · DOI
  37. ESCH, F, PRIMARY STRUCTURE OF BOVINE PITUITARY BASIC FIBROBLAST GROWTH-FACTOR (FGF) AND COMPARISON WITH THE AMINO-TERMINAL SEQUENCE OF BOVINE BRAIN ACIDIC FGF, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82: 6507 (1985).
  38. FENSELAU, A, GROWTH STIMULATION OF CULTURED ENDOTHELIAL CELLS BY TUMOR-CELL HOMOGENATES, CANCER RESEARCH 36: 3269 (1976).
  39. FENSELAU, A, TUMOR ANGIOGENIC FACTOR - PURIFICATION FROM THE WALKER 256 RAT-TUMOR, JOURNAL OF BIOLOGICAL CHEMISTRY 256: 9605 (1981). · DOI
  40. FETT, J.W., ISOLATION AND CHARACTERIZATION OF ANGIOGENIN, AN ANGIOGENIC PROTEIN FROM HUMAN CARCINOMA-CELLS, BIOCHEMISTRY 24: 5480 (1985). · DOI
  41. FOLKMAN, J, ANTI-ANGIOGENESIS - NEW CONCEPT FOR THERAPY OF SOLID TUMORS, ANNALS OF SURGERY 175: 409 (1972). · DOI
  42. FOLKMAN, J, BIOL ENDOTHELIAL CEL: 412 (1984).
  43. FOLKMAN, J, GROWTH AND METASTASIS OF TUMOR IN ORGAN CULTURE, CANCER 16: 453 (1963). · DOI
  44. FOLKMAN, J, CARCINOMA COLON ANTE: 113 (1970).
  45. FOLKMAN, J, IMPORTANT ADV ONCOLO: 42 (1985).
  46. FOLKMAN, J, ISOLATION OF A TUMOR FACTOR RESPONSIBLE FOR ANGIOGENESIS, JOURNAL OF EXPERIMENTAL MEDICINE 133: 275 (1971). · DOI · Paper page
  47. FOLKMAN, J, KAROLINSKA SYMPOSIA ON RESEARCH METHODS IN REPRODUCTIVE ENDOCRINOLOGY: 237 (1971).
  48. FOLKMAN, J, TUMOR ANGIOGENESIS - THERAPEUTIC IMPLICATIONS, NEW ENGLAND JOURNAL OF MEDICINE 285: 1182 (1971). · DOI · Paper page
  49. 10.1038/288551a0 · DOI
  50. FOLKMAN, J, ORGAN PERFUSION PRES: 759 (1968).
  51. FOLKMAN, J, LONG-TERM CULTURE OF CAPILLARY ENDOTHELIAL-CELLS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76: 5217 (1979).
  52. FOLKMAN, J, PATHOBIOLOGY ENDOTHE: 79 (1982).
  53. 10.1126/science.6192498 · DOI
  54. FOLKMAN, M.J., ANN SURG 164: 491 (1966). · DOI
  55. FORM, D.M., PGE2 AND ANGIOGENESIS, PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 172: 214 (1983). · DOI
  56. FRATERSCHRODER, M, TRANSFORMING GROWTH FACTOR-BETA-INHIBITS ENDOTHELIAL-CELL PROLIFERATION, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 137: 295 (1986). · DOI
  57. FREISEL, R, J BIOL CHEM 261: 7581 (1986). · DOI
  58. GIMBRONE, M.A., TUMOR DORMANCY IN-VIVO BY PREVENTION OF NEOVASCULARIZATION, JOURNAL OF EXPERIMENTAL MEDICINE 136: 261 (1972). · DOI
  59. GIMBRONE, M.A., TUMOR-GROWTH AND NEOVASCULARIZATION - EXPERIMENTAL MODEL USING RABBIT CORNEA, JOURNAL OF THE NATIONAL CANCER INSTITUTE 52: 413 (1974). · DOI
  60. GIMBRONE, M.A., PRESERVATION OF VASCULAR INTEGRITY IN ORGANS PERFUSED IN VITRO WITH A PLATELET-RICH MEDIUM, NATURE 222: 33 (1969). · DOI
  61. GIMBRONE, M.A., SERIES HAEMATOLOGICA 6: 453 (1973).
  62. 10.1126/science.4071057 · DOI
  63. GOSPODAROWICZ, D, ENDOCRINOLOGY 117: 2283 (1985).
  64. GOSPODAROWICZ, D, ISOLATION OF FIBROBLAST GROWTH-FACTOR FROM BOVINE ADRENAL-GLAND - PHYSICOCHEMICAL AND BIOLOGICAL CHARACTERIZATION, ENDOCRINOLOGY 118: 82 (1986). · DOI
  65. GOSPODAROWICZ, D, PURIFICATION OF FIBROBLAST GROWTH-FACTOR ACTIVITY FROM BOVINE BRAIN, JOURNAL OF BIOLOGICAL CHEMISTRY 253: 3736 (1978). · DOI
  66. GOSPODAROWICZ, D, HEPARIN PROTECTS BASIC AND ACIDIC FGF FROM INACTIVATION, JOURNAL OF CELLULAR PHYSIOLOGY 128: 475 (1986). · DOI · Paper page
  67. GOSPODAROWICZ, D, CLONAL GROWTH OF BOVINE VASCULAR ENDOTHELIAL CELLS - FIBROBLAST GROWTH-FACTOR AS A SURVIVAL AGENT, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73: 4120 (1976).
  68. GOSPODAROWICZ, D, ISOLATION OF BRAIN FIBROBLAST GROWTH-FACTOR BY HEPARIN-SEPHAROSE AFFINITY-CHROMATOGRAPHY - IDENTITY WITH PITUITARY FIBROBLAST GROWTH-FACTOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 6963 (1984).
  69. GREENBLATT, M, TUMOR ANGIOGENESIS - TRANSFILTER DIFFUSION STUDIES IN HAMSTER BY TRANSPARENT CHAMBER TECHNIQUE, JOURNAL OF THE NATIONAL CANCER INSTITUTE 41: 111 (1968).
  70. GROSS, J.L., INCREASED CAPILLARY ENDOTHELIAL-CELL PROTEASE ACTIVITY IN RESPONSE TO ANGIOGENIC STIMULI INVITRO, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80: 2623 (1983).
  71. GRUSHKA, E, THE BINDING OF CU(II) AND ZN(II) IONS BY HEPARIN, ANALYTICAL LETTERS PART B-CLINICAL AND BIOCHEMICAL ANALYSIS 15: 1277 (1982).
  72. HAUSCHKA, P.V., GROWTH-FACTORS IN BONE-MATRIX - ISOLATION OF MULTIPLE TYPES BY AFFINITY-CHROMATOGRAPHY ON HEPARIN-SEPHAROSE, JOURNAL OF BIOLOGICAL CHEMISTRY 261: 12665 (1986). · DOI
  73. HEIMARK, R.L., INHIBITION OF ENDOTHELIAL REGENERATION BY TYPE-BETA TRANSFORMING GROWTH-FACTOR FROM PLATELETS, SCIENCE 233: 1078 (1986). · DOI
  74. HERTIG, A.T., CONTRIBUTIONS TO EMBRYOLOGY 25: 37 (1935).
  75. HUANG, S.S., ASSOCIATION OF BOVINE BRAIN-DERIVED GROWTH-FACTOR RECEPTOR WITH PROTEIN TYROSINE KINASE-ACTIVITY, JOURNAL OF BIOLOGICAL CHEMISTRY 261: 9568 (1986). · DOI
  76. IDE, A.G., AMERICAN JOURNAL OF ROENTGENOLOGY 42: 891 (1939).
  77. INGBER, D.E., A POSSIBLE MECHANISM FOR INHIBITION OF ANGIOGENESIS BY ANGIOSTATIC STEROIDS - INDUCTION OF CAPILLARY BASEMENT-MEMBRANE DISSOLUTION, ENDOCRINOLOGY 119: 1768 (1986). · DOI
  78. JAFFE, E.A., CULTURE OF HUMAN ENDOTHELIAL CELLS DERIVED FROM UMBILICAL-CORD VEINS, JOURNAL OF CLINICAL INVESTIGATION 51: A46 (1972).
  79. 10.1126/science.3523756 · DOI
  80. KADISH, J.L., EFFECT OF FIBRIN ON CULTURED VASCULAR ENDOTHELIAL-CELLS, TISSUE & CELL 11: 99 (1979). · DOI
  81. KESSLER, D.A., MAST-CELLS AND TUMOR ANGIOGENESIS, INTERNATIONAL JOURNAL OF CANCER 18: 703 (1976). · DOI
  82. KLAGSBRUN, M, TUMOR ANGIOGENESIS ACTIVITY IN CELLS GROWN IN TISSUE-CULTURE, CANCER RESEARCH 36: 110 (1976).
  83. KLAGSBRUN, M, PURIFICATION OF A CARTILAGE-DERIVED GROWTH-FACTOR, JOURNAL OF BIOLOGICAL CHEMISTRY 255: 10859 (1980). · DOI
  84. Klagsbrun, M., Proceedings of the National Academy of Sciences of the United States of America 84: 1839 (1987).
  85. KLAGSBRUN, M, HUMAN-TUMOR CELLS SYNTHESIZE AN ENDOTHELIAL-CELL GROWTH-FACTOR THAT IS STRUCTURALLY RELATED TO BASIC FIBROBLAST GROWTH-FACTOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 2448 (1986).
  86. KLAGSBRUN, M, HEPARIN AFFINITY OF ANIONIC AND CATIONIC CAPILLARY ENDOTHELIAL CELL-GROWTH FACTORS - ANALYSIS OF HYPOTHALAMUS-DERIVED GROWTH-FACTORS AND FIBROBLAST GROWTH-FACTORS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82: 805 (1985).
  87. KNIGHTON, D.R., CLASSIFICATION AND TREATMENT OF CHRONIC NONHEALING WOUNDS - SUCCESSFUL TREATMENT WITH AUTOLOGOUS PLATELET-DERIVED WOUND-HEALING FACTORS (PDWHF), ANNALS OF SURGERY 204: 322 (1986). · DOI
  88. KNIGHTON, D.R., OXYGEN-TENSION REGULATES THE EXPRESSION OF ANGIOGENESIS FACTOR BY MACROPHAGES, SCIENCE 221: 1283 (1983). · DOI · Paper page
  89. KRAMER, R.H., SOLUBILIZATION AND DEGRADATION OF SUB-ENDOTHELIAL MATRIX GLYCOPROTEINS AND PROTEOGLYCANS BY METASTATIC TUMOR-CELLS, JOURNAL OF BIOLOGICAL CHEMISTRY 257: 2678 (1982). · DOI
  90. KREYBERG, L, On local alterations of the blood-vessels of tar-painted white mice., BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY 8: 465 (1927).
  91. KUMAR, S, HUMAN-LUNG TUMOR-CELL LINE ADAPTED TO GROW IN SERUM-FREE MEDIUM SECRETES ANGIOGENESIS FACTOR, INTERNATIONAL JOURNAL OF CANCER 32: 461 (1983). · DOI
  92. KURACHI, K, BIOCHEMISTRY-US 24: 5494 (1985). · DOI
  93. LANGER, R, CONTROL OF TUMOR-GROWTH IN ANIMALS BY INFUSION OF AN ANGIOGENESIS INHIBITOR, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77: 4331 (1980).
  94. LOBB, R, PURIFICATION AND CHARACTERIZATION OF HEPARIN-BINDING ENDOTHELIAL-CELL GROWTH-FACTORS, JOURNAL OF BIOLOGICAL CHEMISTRY 261: 1924 (1986). · DOI
  95. LOBB, R.R., PURIFICATION OF 2 DISTINCT GROWTH-FACTORS FROM BOVINE NEURAL TISSUE BY HEPARIN AFFINITY-CHROMATOGRAPHY, BIOCHEMISTRY 23: 6295 (1984). · DOI
  96. LOBB, R.R., INDUCTION OF ANGIOGENESIS BY BOVINE BRAIN DERIVED CLASS-1 HEPARIN-BINDING GROWTH-FACTOR, BIOCHEMISTRY 24: 4969 (1985). · DOI
  97. LONG, W.F., MEDICAL HYPOTHESES 13: 385 (1980).
  98. Maciag, T., Growth of Cells in Hormonally Defined Media, Book A: 525 (1982).
  99. MACIAG, T, ENDOTHELIAL CELL-GROWTH FACTOR FROM BOVINE HYPOTHALAMUS - IDENTIFICATION AND PARTIAL CHARACTERIZATION, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 76: 5674 (1979).
  100. 10.1126/science.6382607 · DOI
  101. 10.1126/science.6320373 · DOI
  102. MCAUSLAN, B.R., ENDOTHELIUM STIMULATING FACTOR FROM WALKER CARCINOMA-CELLS - RELATION TO TUMOR ANGIOGENIC FACTOR, EXPERIMENTAL CELL RESEARCH 119: 181 (1979). · DOI
  103. MCAUSLAN, B.R., ENDOTHELIAL-CELL PHAGOKINESIS IN RESPONSE TO SPECIFIC METAL-IONS, EXPERIMENTAL CELL RESEARCH 130: 147 (1980). · DOI
  104. MOENNER, M, EVIDENCE AND CHARACTERIZATION OF THE RECEPTOR TO EYE-DERIVED GROWTH FACTOR-I, THE RETINAL FORM OF BASIC FIBROBLAST GROWTH-FACTOR, ON BOVINE EPITHELIAL LENS CELLS, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 5024 (1986).
  105. MOSCATELLI, D, PURIFICATION OF A FACTOR FROM HUMAN-PLACENTA THAT STIMULATES CAPILLARY ENDOTHELIAL-CELL PROTEASE PRODUCTION, DNA-SYNTHESIS, AND MIGRATION, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 2091 (1986).
  106. 10.1126/science.472760 · DOI
  107. NEUFELD, G, THE IDENTIFICATION AND PARTIAL CHARACTERIZATION OF THE FIBROBLAST GROWTH-FACTOR RECEPTOR OF BABY HAMSTER-KIDNEY CELLS, JOURNAL OF BIOLOGICAL CHEMISTRY 260: 13860 (1985). · DOI
  108. NICOSIA, R.F., ANGIOGENESIS-DEPENDENT TUMOR SPREAD IN REINFORCED FIBRIN CLOT CULTURE, CANCER RESEARCH 43: 2159 (1983).
  109. OLWIN, B.B., IDENTIFICATION OF THE FIBROBLAST GROWTH-FACTOR RECEPTOR OF SWISS-3T3 CELLS AND MOUSE SKELETAL-MUSCLE MYOBLASTS, BIOCHEMISTRY 25: 3487 (1986). · DOI
  110. ORLIDGE, A, PERICYTE AND SMOOTH-MUSCLE CELL MODULATION OF ENDOTHELIAL-CELL PROLIFERATION, JOURNAL OF CELL BIOLOGY 103: A471 (1986).
  111. PHILLIPS, P, TUMOR ANGIOGENESIS FACTOR (TAF) IN HUMAN AND ANIMAL TUMORS, INTERNATIONAL JOURNAL OF CANCER 17: 549 (1976). · DOI
  112. POLVERINI, P.J., INDUCTION OF NEOVASCULARIZATION INVIVO AND ENDOTHELIAL PROLIFERATION INVITRO BY TUMOR-ASSOCIATED MACROPHAGES, LABORATORY INVESTIGATION 51: 635 (1984).
  113. RAJU, K.S., CHARACTERIZATION OF A CHEMOATTRACTANT FOR ENDOTHELIUM INDUCED BY ANGIOGENESIS EFFECTORS, CANCER RESEARCH 44: 1579 (1984).
  114. ROBERTS, A.B., TRANSFORMING GROWTH-FACTOR TYPE-BETA - RAPID INDUCTION OF FIBROSIS AND ANGIOGENESIS INVIVO AND STIMULATION OF COLLAGEN FORMATION INVITRO, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83: 4167 (1986).
  115. SANDISON, J.C., Contraction of blood vessels and observations on the circulation in the transparent chamber in the rabbit's ear, ANATOMICAL RECORD 54: 105 (1932). · DOI
  116. SCHREIBER, A.B., A UNIQUE FAMILY OF ENDOTHELIAL-CELL POLYPEPTIDE MITOGENS - THE ANTIGENIC AND RECEPTOR CROSS-REACTIVITY OF BOVINE ENDOTHELIAL-CELL GROWTH-FACTOR, BRAIN-DERIVED ACIDIC FIBROBLAST GROWTH-FACTOR, AND EYE-DERIVED GROWTH FACTOR-II, JOURNAL OF CELL BIOLOGY 101: 1623 (1985). · DOI
  117. SCHREIBER, A.B., INTERACTION OF ENDOTHELIAL-CELL GROWTH-FACTOR WITH HEPARIN - CHARACTERIZATION BY RECEPTOR AND ANTIBODY RECOGNITION, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82: 6138 (1985).
  118. 10.1126/science.2422759 · DOI
  119. 10.1126/science.6823562 · DOI
  120. SHAPIRO, R, CHARACTERISTIC RIBONUCLEOLYTIC ACTIVITY OF HUMAN ANGIOGENIN, BIOCHEMISTRY 25: 3527 (1986). · DOI
  121. SHING, Y, ANGIOGENESIS IS STIMULATED BY A TUMOR-DERIVED ENDOTHELIAL-CELL GROWTH-FACTOR, JOURNAL OF CELLULAR BIOCHEMISTRY 29: 275 (1985). · DOI
  122. SHING, Y, PURIFICATION BY AFFINITY-CHROMATOGRAPHY ON HEPARIN-SEPHAROSE OF A GROWTH-FACTOR THAT STIMULATES CAPILLARY ENDOTHELIAL CELL-PROLIFERATION, JOURNAL OF CELL BIOLOGY 97: A395 (1983).
  123. 10.1126/science.6199844 · DOI
  124. SHIPLEY, G.D., TYPE-BETA TRANSFORMING GROWTH-FACTOR GROWTH INHIBITOR STIMULATES ENTRY OF MONOLAYER-CULTURES OF AKR-2B CELLS INTO S-PHASE AFTER A PROLONGED PREREPLICATIVE INTERVAL, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82: 4147 (1985).
  125. STIVALA, S.S., PHYSICOCHEMICAL PROPERTIES OF HEPARIN, AND ITS INTERACTION WITH CU(II) AND CALCIUM IN RELATION TO ANTICOAGULATION, FEDERATION PROCEEDINGS 36: 83 (1977).
  126. STRYDOM, D.J., AMINO-ACID SEQUENCE OF HUMAN-TUMOR DERIVED ANGIOGENIN, BIOCHEMISTRY 24: 5486 (1985). · DOI
  127. SULLIVAN, R, PURIFICATION OF CARTILAGE-DERIVED GROWTH-FACTOR BY HEPARIN AFFINITY-CHROMATOGRAPHY, JOURNAL OF BIOLOGICAL CHEMISTRY 260: 2399 (1985). · DOI
  128. TANNOCK, I.F., RELATION BETWEEN CELL PROLIFERATION AND VASCULAR SYSTEM IN A TRANSPLANTED MOUSE MAMMARY TUMOUR, BRITISH JOURNAL OF CANCER 22: 258 (1968). · DOI · Paper page
  129. TANNOCK, I.F., POPULATION KINETICS OF CARCINOMA CELLS, CAPILLARY ENDOTHELIAL CELLS, AND FIBROBLASTS IN A TRANSPLANTED MOUSE MAMMARY TUMOR, CANCER RESEARCH 30: 2470 (1970).
  130. TAYLOR, S, PROTAMINE IS AN INHIBITOR OF ANGIOGENESIS, NATURE 297: 307 (1982). · DOI
  131. THIESSEN, N.W., The vascularity of benign and malignant lesions of the stomach - A comparative study with clinical correlations, SURGERY GYNECOLOGY & OBSTETRICS 63: 149 (1936).
  132. THOMAS, K.A., PURIFICATION AND CHARACTERIZATION OF ACIDIC FIBROBLAST GROWTH-FACTOR FROM BOVINE BRAIN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81: 357 (1984).
  133. THOMAS, K.A., PURE BRAIN-DERIVED ACIDIC FIBROBLAST GROWTH-FACTOR IS A POTENT ANGIOGENIC VASCULAR ENDOTHELIAL-CELL MITOGEN WITH SEQUENCE HOMOLOGY TO INTERLEUKIN-1, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 82: 6409 (1985).
  134. 10.1126/science.6635659 · DOI
  135. TUAN, D, ISOLATION OF NONHISTONE PROTEINS OF RAT WALKER CARCINOMA-256 - THEIR ASSOCIATION WITH TUMOR ANGIOGENESIS, BIOCHEMISTRY 12: 3159 (1973). · DOI
  136. UENO, N, ISOLATION OF AN AMINO TERMINAL EXTENDED FORM OF BASIC FIBROBLAST GROWTH-FACTOR, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 138: 580 (1986). · DOI
  137. VLODAVSKY, I, HEPARIN BINDING ENDOTHELIAL-CELL GROWTH-FACTOR PRODUCED BY ENDOTHELIAL-CELLS AND SEQUESTERED BY THE SUBENDOTHELIAL EXTRACELLULAR-MATRIX, JOURNAL OF CELL BIOLOGY 103: A98 (1986).
  138. Warren, B. A., Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental Human Tumors: 1 (1979).
  139. WATT, S.L., A MITOGENIC FACTOR FOR ENDOTHELIAL-CELLS OBTAINED FROM MOUSE SECONDARY MIXED LEUKOCYTE-CULTURES, JOURNAL OF IMMUNOLOGY 136: 197 (1986). · DOI
  140. Wissler, J. H., Biochemistry of Differentiation and Morphogenesis: 257 (1982).
  141. ZETTER, B.R., MIGRATION OF CAPILLARY ENDOTHELIAL-CELLS IS STIMULATED BY TUMOUR-DERIVED FACTORS, NATURE 285: 41 (1980). · DOI
  142. ZICHE, M, ROLE OF PROSTAGLANDIN-E1 AND COPPER IN ANGIOGENESIS, JOURNAL OF THE NATIONAL CANCER INSTITUTE 69: 475 (1982).

Cited by

Sorted by citations

Metadata

Authors
Folkman, J., & Klagsbrun, M.
Affiliations
Department of Surgery, Children's Hospital, Boston, MA 02115, and the Departments of Surgery, Anatomy and Cellular Biology, and Biological Chemistry, Harvard Medical School, Boston, MA 02115.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
1987-01-23
Volume
235
Issue
4787
Pages
442-447
ISSN
  • 0036-8075
  • 1095-9203
DOI
10.1126/science.2432664
Cited by
3,491
References
3
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review