Androgen-insensitive rats are defeminised by their testes
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Castration during the neonatal period prior to postnatal day 10 in both tfm and WT males, in contrast to castration after postnatal day 10, is necessary to induce lordosis with estrogen treatment in adulthood.
“In addition, it has been shown that castration during the neonatal period prior to postnatal day 10 (Olsen, 1979a), in both the tfm and WT males, in contrast to castration after postnatal day 10 (Olsen & Whalen, 1981), is necessary to induce lordosis with estrogen treatment in adulthood.”
From Play fighting in androgen-insensitivetfm rats: Evidence that androgen receptors are necessary for the development of adult playful attack and defense (2006) · cites this paper as Olsen, 1979a
Cites
X-linked Gene for Testicular Feminization in the Mouse
LYON, M. F., & HAWKES, S. G. (1970) · Nature · doi:10.1038/2271217a0 · Cited by 555 · see citing works
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Walters, K. A., Simanainen, U., & Handelsman, D. J. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq003 · Cited by 183 · see citing works
Shapiro, B. H., Levine, D. C., & Adler, N. T. (1980) · Science · doi:10.1126/science.7384816 · Cited by 41 · see citing works
Field, E. F., Whishaw, I. Q., Pellis, S. M., & Watson, N. V. (2006) · Developmental Psychobiology · doi:10.1002/dev.20121 · Cited by 30 · see citing works
Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats
Olsen, K. L., & Whalen, R. E. (1982) · Experientia · doi:10.1007/bf01944575 · Cited by 17 · see citing works
Self-citationField, E. F., Watson, N. V., Whishaw, I. Q., & Pellis, S. M. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.08.007 · Cited by 10 · see citing works
- Authors
- OLSEN, K. L.
- Affiliations
- Boston Children's Hospital (US)
- Corresponding author
- OLSEN, K. L.
- Venue
- Nature
- Published
- 1979-05
- Volume
- 279
- Issue
- 5710
- Pages
- 238-239
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2002675508
- Cited by
- 52
- References
- 1
- Citations by year
- 2020: 1 · 2019: 1 · 2017: 1 · 2016: 1 · 2012: 1
- FWCI
- 1.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sexual Differentiation and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Keywords
- androgen insensitivity syndrome, XY sex reversal, ovarian hormones, female sexual behavior
- MeSH terms
- Age Factors, Animals, Castration, Estradiol, Male, Progesterone, Sexual Behavior, Animal, Species Specificity, Androgen-Insensitivity Syndrome, Testis, Rats
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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