X-linked Gene for Testicular Feminization in the Mouse

Sex Chromosomes and Sex-Linked Genes

Ohno, S. (1967) · Monographs on endocrinology · doi:10.1007/978-3-642-88178-7 · Cited by 1,497 · see citing works

Sex Chromosomes and Sex-linked Genes.

(1968) · Annals of Internal Medicine · doi:10.7326/0003-4819-68-6-1375_2 · Cited by 1,324 · see citing works

Wilkins the Diagnosis and Treatment of Endocrine Disorders in Childhood and Adolescence

Kappy, M. S., Blizzard, R. M., Migeon, C. J., & Wilkins, L. (1994) · Medical Entomology and Zoology · Cited by 898 · see citing works

The Diagnosis and Treatment of Endocrine Disorders in Childhood and Adolescence

Wilkins, L. (1951) · Southern Medical Journal · doi:10.1097/00007611-195105000-00033 · Cited by 273 · see citing works

Biosynthesis of Secondary Metabolites: Roles of Trace Metals

Weinberg, E. D. (1969) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/s0065-2911(08)60438-5 · Cited by 181 · see citing works

A simple method for preparing meiotic chromosomes from mammalian testis

Meredith, R. (1969) · Chromosoma · doi:10.1007/bf00326520 · Cited by 172 · see citing works

Mammalian Oocytes: X Chromosome Activity

Epstein, C. J. (1969) · Science · doi:10.1126/science.163.3871.1078 · Cited by 150 · see citing works

Differential rate of ribonucleic acid synthesis in the autosomes and sex chromosomes during male meiosis in the mouse

Monesi, V. (1965) · Chromosoma · doi:10.1007/bf00285153 · Cited by 149 · see citing works

X‐Linked testicular feminization in the mouse as a non‐inducible regulatory mutation of the Jacob‐Monod type

Ohno, S., & Lyon, M. F. (1970) · Clinical Genetics · doi:10.1111/j.1399-0004.1970.tb01627.x · Cited by 101 · see citing works

Pseudohermaphrodite Rat: End Organ Insensitivity to Testosterone

Bardin, C. W., Bullock, L. P., SCHNEIDER, G. T., Allison, J. E., & Stanley, A. J. (1970) · Science · doi:10.1126/science.167.3921.1136 · Cited by 79 · see citing works

Further Evidence of a Target Organ Defect in the Syndrome of Testicular Feminization1

French, F. S., Wyk, J. J. V., Baggett, B., EASTERLING, W. E., Talbert, L. M., JOHNSTON, R. F., Forchielli, E., & Dey, A. C. (1966) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-26-5-493 · Cited by 77 · see citing works

More about the testosterone induction of kidney alcohol dehydrogenase activity in the mouse

Ohno, S., Stenius, C., Christian, L., Harris, C., & Ivey, C. (1970) · Biochemical Genetics · doi:10.1007/bf00486095 · Cited by 72 · see citing works

Absence of response to dihydrotestosterone in the syndrome of testicular feminization

STRICKLAND, A. L., & FRENCH, F. S. (1969) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-29-9-1284 · Cited by 50 · see citing works

Reproduction

Short, R. V. (1967) · Annual Review of Physiology · doi:10.1146/annurev.ph.29.030167.002105 · Cited by 46 · see citing works

Late DNA Replication in Male Mouse Meiotic Chromosomes

Odartchenko, N., & Pavillard, M. (1970) · Science · doi:10.1126/science.167.3921.1133 · Cited by 36 · see citing works

Reproduction

Armstrong, D. T. (1970) · Annual Review of Physiology · doi:10.1146/annurev.ph.32.030170.002255 · Cited by 20 · see citing works

Inheritance of testicular feminization syndrome: some negative linkage findings.

Sanger, R. A., Tippett, P., Gavin, J., Gooch, A., & Race, R. R. (1969) · Journal of Medical Genetics · doi:10.1136/jmg.6.1.26 · Cited by 12 · see citing works

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

Couse, J. F., & Korach, K. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0370 · Cited by 2,045 · see citing works

Androgen Receptor in Prostate Cancer

Heinlein, C. A., & Chang, C. (2004) · Endocrine Reviews · doi:10.1210/er.2002-0032 · Cited by 1,780 · see citing works

Androgen Receptor Defects: Historical, Clinical, and Molecular Perspectives*

Quigley, C. A., Bellis, A. D., Marschke, K. B., Awady, M. K. E., Wilson, E. M., & French, F. S. (1995) · Endocrine Reviews · doi:10.1210/edrv-16-3-271 · Cited by 1,436 · see citing works

Cloning of Human Androgen Receptor Complementary DNA and Localization to the X Chromosome

Lubahn, D. B., JOSEPH, D. R., Sullivan, P. M., Willard, H. F., French, F. S., & Wilson, E. M. (1988) · Science · doi:10.1126/science.3353727 · Cited by 1,003 · see citing works

Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

Chang, C. S., Kokontis, J. M., & Liao, S. (1988) · Science · doi:10.1126/science.3353726 · Cited by 891 · see citing works

The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and Organization

Shreffler, D. C., & David, C. S. (1975) · Advances in immunology · doi:10.1016/s0065-2776(08)60208-4 · Cited by 761 · see citing works

Cryptorchidism in mice mutant for Insl3

Nef, S., & Parada, L. F. (1999) · Nature Genetics · doi:10.1038/10364 · Cited by 731 · see citing works

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

Nguyen, L. P., & Bradfield, C. A. (2007) · Chemical Research in Toxicology · doi:10.1021/tx7001965 · Cited by 705 · see citing works

Roles for Nkx3.1 in prostate development and cancerPreprint

Bhatia-Gaur, R., Donjacour, A. A., Sciavolino, P. J., Kim, M., Desai, N., Young, P., Norton, C. R., Gridley, T., Cardiff, R. D., Cunha, G. R., et al. (1999) · Genes & Development · doi:10.1101/gad.13.8.966 · Cited by 669 · see citing works

Studies on Sex Differentiation in Mammals

JOST, A., Vigier, B., Prépin, J., & PERCHELLET, J. P. (1973) · Elsevier eBooks · doi:10.1016/b978-0-12-571129-6.50004-x · Cited by 558 · see citing works

Keratinocyte growth factor is required for hair development but not for wound healing.Preprint

Guo, L., Degenstein, L., & Fuchs, E. V. (1996) · Genes & Development · doi:10.1101/gad.10.2.165 · Cited by 534 · see citing works

Sexually dimorphic sterility phenotypes in HoxalO-deficient mice

Satokata, I., Benson, G., & Maas, R. L. (1995) · Nature · doi:10.1038/374460a0 · Cited by 519 · see citing works

Developmental switch of CREM function during spermatogenesis: from antagonist to activator

Foulkes, N. S., Mellström, B., Benusiglio, E., & Sassone‐Corsi, P. (1992) · Nature · doi:10.1038/355080a0 · Cited by 483 · see citing works

Androgen Receptor Roles in Spermatogenesis and Fertility: Lessons from Testicular Cell-Specific Androgen Receptor Knockout Mice

Wang, R.-S., Yeh, S., Tzeng, C., & Chang, C. (2009) · Endocrine Reviews · doi:10.1210/er.2008-0025 · Cited by 470 · see citing works

Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids

Holdcraft, R. W., & Braun, R. E. (2003) · Development · doi:10.1242/dev.00957 · Cited by 452 · see citing works

The hormonal-control of sexual development

Wilson, J. D., George, F. W., & Griffin, J. E. (1981) · Science · doi:10.1126/science.7010602 · Cited by 451 · see citing works

Abnormal sexual development in transgenic mice chronically expressing Müllerian inhibiting substance

Behringer, R. R., Cate, R. L., Froelick, G. J., Palmiter, R. D., & Brinster, R. L. (1990) · Nature · doi:10.1038/345167a0 · Cited by 432 · see citing works

International Union of Pharmacology. LXV. The Pharmacology and Classification of the Nuclear Receptor Superfamily: Glucocorticoid, Mineralocorticoid, Progesterone, and Androgen Receptors

Lu, N. Z., Wardell, S. E., Burnstein, K. L., DeFranco, D. B., Fuller, P. J., Giguère, V., Hochberg, R. B., McKay, L. I., Renoir, J., Weigel, N. L., et al. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.4.9 · Cited by 425 · see citing works

Testosterone: A Major Determinant of Extragenital Sexual Dimorphism

Bardin, C. W., & Catterall, J. F. (1981) · Science · doi:10.1126/science.7010603 · Cited by 381 · see citing works

The origin and function of the mammalian Y chromosome and Y‐borne genes – an evolving understanding

Graves, J. A. M. (1995) · BioEssays · doi:10.1002/bies.950170407 · Cited by 375 · see citing works

Sex determination, gonadal sex differentiation, and plasticity in vertebrate species

Nagahama, Y., Chakraborty, T., Paul‐Prasanth, B., Ohta, K., & Nakamura, M. (2020) · Physiological Reviews · doi:10.1152/physrev.00044.2019 · Cited by 361 · see citing works

SEX AND THE SINGLE CELL. I. ON THE ACTION OF MAJOR LOCI AFFECTING SEX DETERMINATION IN DROSOPHILA MELANOGASTER

Baker, B. S., & Ridge, K. A. (1980) · Genetics · doi:10.1093/genetics/94.2.383 · Cited by 357 · see citing works

Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism.

The University of North Carolina at Chapel Hill University Libraries (2020) · PubMed · doi:10.17615/zr3n-5f64 · Cited by 356 · see citing works

Possible role for H–Y antigen in the primary determination of sex

Wachtel, S. S., Ohno, S., Koo, G. C., & Boyse, E. A. (1975) · Nature · doi:10.1038/257235a0 · Cited by 355 · see citing works

The Syndromes of Androgen Resistance

Griffin, J. E., & Wilson, J. D. (1980) · New England Journal of Medicine · doi:10.1056/nejm198001243020404 · Cited by 307 · see citing works

Mechanism of Action of the Sex Steroid Hormones

Chan, L., & O’Malley, B. W. (1976) · New England Journal of Medicine · doi:10.1056/nejm197606102942405 · Cited by 293 · see citing works

Hormonal control of germ cell development and spermatogenesis

O’Shaughnessy, P. J. (2014) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2014.02.010 · Cited by 285 · see citing works

A local autocrine axis in the testes that regulates spermatogenesis

Cheng, C. Y., & Mruk, D. D. (2010) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2010.71 · Cited by 278 · see citing works

The Androgen Receptor in Health and Disease

Μatsumoto, T., Sakari, M., Okada, M., Yokoyama, A., Takahashi, S., Kouzmenko, A., & Kato, S. (2012) · Annual Review of Physiology · doi:10.1146/annurev-physiol-030212-183656 · Cited by 268 · see citing works

Hormonal regulation of spermatogenesis

Holdcraft, R. W., & Braun, R. E. (2004) · International Journal of Andrology · doi:10.1111/j.1365-2605.2004.00502.x · Cited by 255 · see citing works

The Androgen Receptor Governs the Execution, but Not Programming, of Male Sexual and Territorial Behaviors

Juntti, S. A., Tollkuhn, J., Wu, M. V., Fraser, E. J., Soderborg, T., Tan, S., Honda, S.-I., Harada, N., & Shah, N. M. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.024 · Cited by 254 · see citing works

Tissue interaction in androgen response of embryonic mammary rudiment of mouse: identification of target tissue for testosterone.

Kratochwil, K., & Schwartz, P. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.11.4041 · Cited by 251 · see citing works

Androgen receptor roles in spermatogenesis and infertility

O’Hara, L., & Smith, L. B. (2015) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2015.04.006 · Cited by 249 · see citing works

Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos

Shackleford, G. M., & VARMUS, H. E. (1987) · Cell · doi:10.1016/0092-8674(87)90665-9 · Cited by 246 · see citing works

Sex reversal in the mouse (Mus musculus) is caused by a recurrent nonreciprocal crossover involving the X and an aberrant Y chromosome

Singh, L., & Jones, K. W. (1982) · Cell · doi:10.1016/0092-8674(82)90338-5 · Cited by 244 · see citing works

Hormonal and cellular regulation of Sertoli cell anti-Müllerian hormone production in the postnatal mouse.

Al-Attar, L., Noël, K., Dutertre, M., Belville, C., Forest, M. G., Burgoyne, P. S., Josso, N., & Rey, R. A. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119653 · Cited by 233 · see citing works

Epithelial-Stromal Interactions in Development of the Urogenital Tract

Cunha, G. R. (1976) · International review of cytology · doi:10.1016/s0074-7696(08)60088-1 · Cited by 230 · see citing works

Physical androgyny and cognitive functioning in adolescence.

Petersen, A. C. (1976) · Developmental Psychology · doi:10.1037/0012-1649.12.6.524 · Cited by 226 · see citing works

The Androgen Receptor: An Overview

Zhou, Z.-X., Wong, C.-I., Sar, M., & Wilson, E. (1994) · Elsevier eBooks · doi:10.1016/b978-0-12-571149-4.50017-9 · Cited by 218 · see citing works

Conditional Inactivation of Androgen Receptor Gene in the Nervous System: Effects on Male Behavioral and Neuroendocrine Responses

Raskin, K., de Gendt, K., Duittoz, A., Liere, P., Verhoeven, G., Tronche, F., & Mhaouty-Kodja, S. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0296-09.2009 · Cited by 218 · see citing works

Essential Role of Fkbp6 in Male Fertility and Homologous Chromosome Pairing in Meiosis

Crackower, M. A., Kolas, N. K., Noguchi, J., Sarao, R., Kikuchi, K., Kaneko, H., Kobayashi, E., Kawai, Y., Kozieradzki, I., Landers, R., et al. (2003) · Science · doi:10.1126/science.1083022 · Cited by 211 · see citing works

Deletion of the steroid-binding domain of the human androgen receptor gene in one family with complete androgen insensitivity syndrome: evidence for further genetic heterogeneity in this syndrome.

Brown, T. R., Lubahn, D. B., Wilson, E. M., JOSEPH, D. R., French, F. S., & Migeon, C. J. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.21.8151 · Cited by 209 · see citing works

Prostate organogenesis: tissue induction, hormonal regulation and cell type specification

Toivanen, R., & Shen, M. M. (2017) · Development · doi:10.1242/dev.148270 · Cited by 204 · see citing works

Regulation of Sertoli Cell Number and Activity by Follicle-Stimulating Hormone and Androgen during Postnatal Development in the Mouse

Johnston, H. M., Baker, P. J., Abel, M. H., Charlton, H. M., Jackson, G., Fleming, L. M., Kumar, T. R., & O’Shaughnessy, P. J. (2003) · Endocrinology · doi:10.1210/en.2003-1055 · Cited by 199 · see citing works

Assessment of prostatic protein secretion in tissue recombinants made of urogenital sinus mesenchyme and urothelium from normal or androgen- insensitive mice

Donjacour, A. A., & Cunha, G. R. (1993) · Endocrinology · doi:10.1210/endo.132.6.7684975 · Cited by 199 · see citing works

PARASEXUAL APPROACHES TO THE GENETICS OF MAN

Ruddle, F. H., & Creagan, R. P. (1975) · Annual Review of Genetics · doi:10.1146/annurev.ge.09.120175.002203 · Cited by 198 · see citing works

Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

Merry, D. E. (1998) · Human Molecular Genetics · doi:10.1093/hmg/7.4.693 · Cited by 190 · see citing works

Hormones in male sexual developmentPreprint

Nef, S., & Parada, L. F. (2000) · Genes & Development · doi:10.1101/gad.843800 · Cited by 188 · see citing works

Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models

Walters, K. A., Simanainen, U., & Handelsman, D. J. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq003 · Cited by 183 · see citing works

Locus on human X chromosome for dihydrotestosterone receptor and androgen insensitivity.

Meyer, W. J., Migeon, B. R., & Migeon, C. J. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.4.1469 · Cited by 182 · see citing works

Part II. Androgen Metabolism and Mechanism of Action in Male Pseudohermaphroditism: A Study of Testicular Feminization

Bardin, C. W., BULLOCK, L. P., Sherins, R. J., Mowszowicz, I., & Blackburn, W. R. (1973) · Elsevier eBooks · doi:10.1016/b978-0-12-571129-6.50006-3 · Cited by 179 · see citing works

The Role of Estrogen Receptors and Androgen Receptors in Sex Steroid Regulation of B Lymphopoiesis

Smithson, G. M., Couse, J. F., Lubahn, D. B., Korach, K. S., & Kincade, P. W. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.1.27 · Cited by 176 · see citing works

A Frameshift Mutation Destabilizes Androgen Receptor Messenger RNA in theTfmMouse

Charest, N. J., Zhou, Z.-X., Lubahn, D. B., Olsen, K. L., Wilson, E., & French, F. S. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-4-573 · Cited by 175 · see citing works

Conversion from a paracrine to an autocrine mechanism of androgen-stimulated growth during malignant transformation of prostatic epithelial cells.

Gao, J., Arnold, J. T., & Isaacs, J. T. (2001) · PubMed · Cited by 173 · see citing works

Testicular feminization: A model for testicular descent in mice and men

Hutson, J. M. (1986) · Journal of Pediatric Surgery · doi:10.1016/s0022-3468(86)80830-2 · Cited by 172 · see citing works

Androgen insensitivity syndrome: clinical features and molecular defects

Galani, A., Kitsiou‐Tzeli, S., Sofokleous, C., Kanavakis, E., & Kalpini-Mavrou, A. (2008) · HORMONES · doi:10.14310/horm.2002.1201 · Cited by 163 · see citing works

Androgen Receptor (AR) Physiological Roles in Male and Female Reproductive Systems: Lessons Learned from AR-Knockout Mice Lacking AR in Selective Cells1

Chang, C., Lee, S. O., Wang, R.-S., Yeh, S., & Chang, T. (2013) · Biology of Reproduction · doi:10.1095/biolreprod.113.109132 · Cited by 163 · see citing works

Sertoli and Germ Cell Development in Hypogonadal (hpg) Mice Expressing Transgenic Follicle-Stimulating Hormone Alone or in Combination with Testosterone

Haywood, M. C., Spaliviero, J. A., Jimemez, M., King, N. J. C., Handelsman, D. J., & Allan, C. M. (2003) · Endocrinology · doi:10.1210/en.2002-220710 · Cited by 163 · see citing works

Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum

Seifert, A. W., Harfe, B. D., & Cohn, M. J. (2008) · Developmental Biology · doi:10.1016/j.ydbio.2008.03.017 · Cited by 162 · see citing works

A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicularfeminized mouse

He, W. W., Kumar, M. V., & Tindall, D. J. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.9.2373 · Cited by 161 · see citing works

Normal spermatozoa from androgen-resistant germ cells of chimaeric mice and the role of androgen in spermatogenesis

Lyon, M. F., Glenister, P. H., & Lamoreux, M. L. (1975) · Nature · doi:10.1038/258620a0 · Cited by 161 · see citing works

Action of Testosterone on the Differentiation and Secretory Activity of a Target Organ: The Submaxillary Gland of the Mouse

Chrétien, M. (1977) · International review of cytology · doi:10.1016/s0074-7696(08)60101-1 · Cited by 158 · see citing works

Essential role for co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology

Yong, W., Yang, Z., Periyasamy, S., Chen, H., Yucel, S., Li, W., Lin, L. Y., Wolf, I. M., Cohn, M. J., Baskin, L. S., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m609360200 · Cited by 156 · see citing works

Male pseudohermaphroditism: The complexities of male phenotypic development

Imperato‐McGinley, J., & Peterson, R. E. (1976) · The American Journal of Medicine · doi:10.1016/0002-9343(76)90175-3 · Cited by 156 · see citing works

Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization

Goldstein, J. L., & Wilson, J. D. (1972) · Journal of Clinical Investigation · doi:10.1172/jci106966 · Cited by 155 · see citing works

Genetic control of glucuronidase induction in mice

Swank, R. T., Paigen, K., & Ganschow, R. E. (1973) · Journal of Molecular Biology · doi:10.1016/0022-2836(73)90191-5 · Cited by 155 · see citing works

Stromal regulation of epithelial function

Donjacour, A. A., & Cunha, G. R. (1991) · Cancer treatment and research · doi:10.1007/978-1-4615-3940-7_16 · Cited by 154 · see citing works

Sites of Action of Androgens and Follicle Stimulating Hormone on Cells of the Seminiferous Tubule

Fritz, I. B. (1978) · Biochemical Actions of Hormones · doi:10.1016/b978-0-12-452805-5.50012-0 · Cited by 154 · see citing works

Effect of the Androgen-insensitivity Mutation on a Cytoplasmic Receptor for Dihydrotestosterone

Gehring, U., Tomkins, G. M., & Ohno, S. (1971) · Nature New Biology · doi:10.1038/newbio232106a0 · Cited by 151 · see citing works

A single base deletion in the Tfm androgen receptor gene creates a short-lived messenger RNA that directs internal translation initiation.

Gaspar, M.-L., Meo, T., Bourgarel, P., Guénet, J. L., & Tosi, M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.19.8606 · Cited by 149 · see citing works

Female Mice Haploinsufficient for an Inactivated Androgen Receptor (AR) Exhibit Age-Dependent Defects That Resemble the AR Null Phenotype of Dysfunctional Late Follicle Development, Ovulation, and Fertility

Walters, K. A., Allan, C. M., Jimenez, M., Lim, P., Davey, R. A., Zajac, J. D., Illingworth, P. J., & Handelsman, D. J. (2007) · Endocrinology · doi:10.1210/en.2007-0248 · Cited by 147 · see citing works

Postnatal developmental changes in submandibular glands of rats and mice.

Gresik, E. W. (1980) · Journal of Histochemistry & Cytochemistry · doi:10.1177/28.8.6160181 · Cited by 146 · see citing works

Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model

Notini, A. J., Davey, R. A., McManus, J. F., Bate, K. L., & Zajac, J. D. (2005) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.01884 · Cited by 145 · see citing works

Spermatogenesis and Sertoli Cell Activity in Mice Lacking Sertoli Cell Receptors for Follicle-Stimulating Hormone and Androgen

Abel, M. H., Baker, P. J., Charlton, H. M., Monteiro, A., Verhoeven, G., Gendt, K. D., Guillou, F., & O’Shaughnessy, P. J. (2008) · Endocrinology · doi:10.1210/en.2008-0086 · Cited by 142 · see citing works

Review Lecture: Mechanisms and evolutionary origins of variable X-chromosome activity in mammals

Lyon, M. F. (1974) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1974.0073 · Cited by 138 · see citing works

Major regulatory genes for mammalian sexual development

Ohno, S. (1976) · Cell · doi:10.1016/0092-8674(76)90160-4 · Cited by 137 · see citing works

Studies of the locus for androgen receptor: localization on the human X chromosome and evidence for homology with the Tfm locus in the mouse.

Migeon, B. R., Brown, T. R., Axelman, J., & Migeon, C. J. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.10.6339 · Cited by 135 · see citing works

Comparative map for mice and humans

Nadeau, J. H., Davisson, M. T., Doolittle, D. P., Grant, P., Hillyard, A. L., Kosowsky, M., & Roderick, T. H. (1992) · Mammalian Genome · doi:10.1007/bf00778825 · Cited by 132 · see citing works

Timing of androgen receptor disruption and estrogen exposure underlies a spectrum of congenital penile anomalies

Zheng, Z., Armfield, B. A., & Cohn, M. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1515981112 · Cited by 131 · see citing works

Cytosol androgen receptor from kidney of normal and testicular feminized (Tfm) mice

Attardi, B., & Ohno, S. (1974) · Cell · doi:10.1016/0092-8674(74)90012-9 · Cited by 131 · see citing works

Androgens and mammalian male reproductive tract development

Murashima, A., Kishigami, S., Thomson, A. A., & Yamada, G. (2014) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.05.020 · Cited by 121 · see citing works

The Sex Difference in Fetal Lung Surfactant Production

Torday, J. S., & Nielsen, H. C. (1987) · Experimental Lung Research · doi:10.3109/01902148709068811 · Cited by 120 · see citing works

Molecular Mechanisms of Steroid Hormone Action

Higgins, S. J., & Gehring, U. (1978) · Advances in cancer research · doi:10.1016/s0065-230x(08)60650-8 · Cited by 119 · see citing works

Testicular growth and development in puberty

Koskenniemi, J. J., Virtanen, H. E., & Toppari, J. (2017) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000339 · Cited by 118 · see citing works

Environmental effects on fish immune mechanisms.

Bly, J. E., Quiniou, S. M. A., & Clem, L. W. (1997) · PubMed · Cited by 115 · see citing works

A Testis Cytoplasmic RNA-Binding Protein That Has the Properties of a Translational Repressor

Lee, K., Fajardo, M. A., & Braun, R. E. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.6.3023 · Cited by 115 · see citing works

Simplicity of Mammalian Regulatory Systems inferred by Single Gene Determination of Sex Phenotypes

Ohno, S. (1971) · Nature · doi:10.1038/234134a0 · Cited by 114 · see citing works

Induction of androgen receptor formation by epithelium-mesenchyme interaction in embryonic mouse mammary gland.

Heuberger, B., Fitzka, I., Wasner, G., & Kratochwil, K. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.9.2957 · Cited by 112 · see citing works

Human Complete Androgen Insensitivity with Normal Dihydrotestosterone Receptor Binding Capacity in Cultured Genital Skin Fibroblasts: Evidence for a Qualitative Abnormality of the Receptor*

Brown, T. R., Maes, M., Rothwell, S. W., & Migeon, C. J. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-55-1-61 · Cited by 112 · see citing works

Specificity of tissue interaction and origin of mesenchymal cells in the androgen response of the embryonic mammary gland

Dürnberger, H., & Kratochwil, K. (1980) · Cell · doi:10.1016/0092-8674(80)90521-8 · Cited by 107 · see citing works

Additive and Interactive Effects of Genotype and Maternal Environment

Roubertoux, P. L., Nosten‐Bertrand, M., & Carlier, M. (1990) · Advances in the study of behavior · doi:10.1016/s0065-3454(08)60204-1 · Cited by 107 · see citing works

Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy

Thomas, P. S., Fraley, G. S., Damien, V., Woodke, L. B., Zapata, F., Sopher, B. L., Plymate, S. R., & Spada, A. R. L. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl148 · Cited by 105 · see citing works

Androgen Receptor and Mechanism of Androgen Action

Jänne, O. A., Palvimo, J. J., Kallio, P. J., & Mehto, M. (1993) · Annals of Medicine · doi:10.3109/07853899309147863 · Cited by 105 · see citing works

Regression of mouse mammary gland anlagen in recombinants of Tfm and wild-type tissues: testosterone acts via the mesenchyme

Drews, U., & Drews, U. (1977) · Cell · doi:10.1016/0092-8674(77)90027-7 · Cited by 105 · see citing works

Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late‐onset Leydig cell apoptosis in both mice and men

O’Hara, L., McInnes, K. J., Simitsidellis, I., Morgan, S., Atanassova, N. N., Słowikowska‐Hilczer, J., Kula, K., Szarras‐Czapnik, M., Milne, L., Mitchell, R. T., et al. (2014) · The FASEB Journal · doi:10.1096/fj.14-255729 · Cited by 103 · see citing works

Sertoli Cell-Specific Deletion of the Androgen Receptor Compromises Testicular Immune Privilege in Mice1

Meng, J., Greenlee, A. R., Taub, C. J., & Braun, R. E. (2011) · Biology of Reproduction · doi:10.1095/biolreprod.110.090621 · Cited by 102 · see citing works

Evolutionary Aspects of Cellular Communication in the Vertebrate Hypothalamo–Hypophysio–Gonadal Axis

Pierantoni, R., Cobellis, G., Meccariello, R., & Fasano, S. (2002) · International review of cytology · doi:10.1016/s0074-7696(02)18012-0 · Cited by 101 · see citing works

Chapter 2 Biochemistry of Male Germ Cell Differentiation in Mammals: RNA Synthesis in Meiotic and Postmeiotic Cells

Monesi, V., Geremia, R., D'Agostino, A., & Boitani, C. (1978) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)60592-x · Cited by 101 · see citing works

Sex determination in mammals

McLaren, A. L. D. (1988) · Trends in Genetics · doi:10.1016/0168-9525(88)90020-0 · Cited by 101 · see citing works

Characterization of a hormone receptor defect in the androgen-insensitivity mutant

Gehring, U., & Tomkins, G. M. (1974) · Cell · doi:10.1016/0092-8674(74)90040-3 · Cited by 101 · see citing works

Animal model, x-linked testicular feminization mutation of the mouse.

Ohno, S. (1974) · The Mouseion at the JAXlibrary (Jackson Laboratory)

Location of the gene for testicular feminization in the X chromosome in man.

Frota‐Pessoa, O., Frehse, G., Parreiras, I., Perez, C. A., Cc, O., & Russo, M. (1971) · PubMed

Expression of H–Y (male) antigen in phenotypically female Tfm/Y mice

Bennett, D., Boyse, E. A., Lyon, M. F., Mathieson, B. J., Scheid, M. P., & Yanagisawa, K. (1975) · Nature · doi:10.1038/257236a0 · Cited by 58 · see citing works

Microscopic epididymides in testicular feminisation

Blecher, S. R. (1978) · Nature · doi:10.1038/275748a0 · Cited by 12 · see citing works

The mutations sex reversal (sxr) and testicular feminisation (tfm) in the mouse and the induction of enzymes by oestrogen and testosterone. Abstr.

Bulfield, G. (1976) · The Mouseion at the JAXlibrary (Jackson Laboratory)