The DOI matches its Crossref record; 28 of the 29 references it cites were found in a registry or an index.
The function of dream sleep
Abstract
We propose that the function of dream sleep (more properly rapid-eye movement or REM sleep) is to remove certain undesirable modes of interaction in networks of cells in the cerebral cortex. We postulate that this is done in REM sleep by a reverse learning mechanism (see also p. 158), so that the trace in the brain of the unconscious dream is weakened, rather than strengthened, by the dream.
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“Notably, Francis Crick and Graeme Mitchinson proposed an alternative purpose for dreams in 1983, which they called “reverse learning.”82,83 In this hypothesis, the point of dreaming is somehow to remove “undesirable” connections and help the brain “unlearn.””
From The overfitted brain: Dreams evolved to assist generalization (2021) · cites this paper as [82]
In the citing paper
“Overall, these findings speak against the view posed by Crick and Mitchison (236).”
From About Sleep's Role in Memory (2013) · cites this paper as [236]
Citations
Cites
Roffwarg, H. P., Muzio, J. N., & Dement, W. C. (1966) · Science · doi:10.1126/science.152.3722.604 · Cited by 1,559
The brain as a dream state generator: an activation-synthesis hypothesis of the dream process
Hobson, J. A., & McCarley, R. W. (1977) · American Journal of Psychiatry · doi:10.1176/ajp.134.12.1335 · Cited by 984
Parallel models of associative memory
Hinton, G. E., & Anderson, J. A. (1981) · CERN Document Server (European Organization for Nuclear Research) · Cited by 927
Dement, W. (1960) · Science · doi:10.1126/science.131.3415.1705 · Cited by 621
A mathematical theory of visual hallucination patterns
Ermentrout, B., & Cowan, J. D. (1979) · Biological Cybernetics · doi:10.1007/bf00336965 · Cited by 594
The Organization of the Cerebral Cortex.
Hawkes, A. G., Adelman, G., Dennis, S. G., Schmitt, F. O., & Warden, F. G. (1982) · Biometrics · doi:10.2307/2529917 · Cited by 583
Kohonen, T. (1977) · Communication and Cybernetics · doi:10.1007/978-3-642-96384-1 · Cited by 469
Palm, G. (1982) · Studies of brain function · doi:10.1007/978-3-642-81792-2 · Cited by 457
‘Unlearning’ has a stabilizing effect in collective memories
Hopfield, J. J., Feinstein, D. I., & Palmer, R. G. (1983) · Nature · doi:10.1038/304158a0 · Cited by 420
Neural Assemblies: An Alternative Approach to Artificial Intelligence
Palm, G. (1982) · MPG.PuRe (Max Planck Society) · Cited by 301
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1 of the 29 references couldn’t be matched to a known paper.
Research works printed but not linked: 9
- Hobson, J.A., McCarley, R.W. & Nelson, J.P. J. Neurophysiol. (in the press).
- Allison, T. & Van Twyver, H. Nat. Hist. 79, 56–65 (1970).
- Klein, M., Michel, F. & Jouvet, M. C.r. hebd. Séanc. Acad. Sci., Paris 158, 99–103 (1964).
- Jouvet, M. Archs. ital. Biol. 100, 125–206 (1962).
- Dewan, E.M. in Sleep and Dreaming (ed. Hartmann, E.) 295–307 (Little-Brown, Boston, 1970).
- Hobson, J.A. in Brain Mechanisms and Perceptual Awareness (eds Pompeiano, O. & Marsan, C. A.) 379–404 (Raven, New York, 1981).
- Dement, W. in Academy of Psychoanalysis: Science and Psychoanalysis Vol. 7 (ed. Masserman, J.) 129–184 (Grune and Stratton, New York, 1964).
- Griffiths, M. The Biology of Monotremes (Academic, New York, 1978).
- Allison, T., Van Twyner, H. & Goff, W.R. Archs. ital. biol. 110, 145–184 (1972).
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Амари, Ш.-И. (1987) · Systems and Computers in Japan · doi:10.1002/scj.4690180704
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Holmström, R., & Lauerma, H. (1989) · Nordic Journal of Psychiatry · doi:10.3109/08039488909098652
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Cameron, D. (2001) · USC Research Bank (University of the Sunshine Coast) · doi:10.25907/00575
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Moffitt, A. R., Hoffmann, R. F., Mullington, J. M., Purcell, S., Pigeau, R., & Wells, R. (1988)
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Eagleman, D. M. (2004) · Vision Research · doi:10.1016/j.visres.2004.08.022
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McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.012
Jitsev, J. (2014) · Lecture notes in computer science · doi:10.1007/978-3-319-11179-7_83
Kovács, I. (2021) · Language, cognition and mind · doi:10.1007/978-3-030-66175-5_18
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Baker, C. I. (2014) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.718084051.793490187
McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.009
McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.007
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McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.013
(1999) · Innovations in psychology · doi:10.1201/9781420048438.bmatt
McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.015
(1998) · Language Learning · doi:10.1111/j.1467-1770.1998.tb00011.x
McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.016
McNamara, P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316817094.003 · Cited by 1
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Metadata
- Authors
- Crick, F., & Mitchison, G.
- Affiliations
- Salk Institute for Biological Studies (US)
- ORCID
- Mitchison, Graeme
- Venue
- Nature
- Published
- 1983-07
- Volume
- 304
- Issue
- 5922
- Pages
- 111-114
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2044707217
- Cited by
- 865
- References
- 29
- Citations by year
- 2026: 8 · 2025: 19 · 2024: 18 · 2023: 23 · 2022: 25 · 2021: 16 · 2020: 14 · 2019: 35 · 2018: 22 · 2017: 23 · 2016: 14 · 2015: 18 · 2014: 34 · 2013: 25 · 2012: 27
- FWCI
- 18.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Profiles in Science (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- REM sleep, dream function, cerebral cortex, neural network interactions, reverse learning
- MeSH terms
- Cerebral Cortex, Dreams, Humans, Models, Psychological, Neurons, Sleep, REM, Synapses
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