cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

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Items 101–200 of 1,002

1. Lipoprotein(a) Catabolism Is Regulated by Proprotein Convertase Subtilisin/Kexin Type 9 through the Low Density Lipoprotein Receptor
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2. Lipoprotein(a) as a risk factor for ischemic heart disease: metaanalysis of prospective studies
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3. Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein(a) Formation
   Stephen James Nicholls, Steven E. Nissen, Cynthia Fleming, Shweta Urva, Jeffrey G. Suico, Paul H. Berg, Helle Linnebjerg, Giacomo Ruotolo, P. Kellie Turner, Laura F. Michael · 2023 · JAMA
4. Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice.
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5. A Prospective Case-Control Study of Lipoprotein(a) Levels and Apo(a) Size and Risk of Coronary Heart Disease in Stanford Five-City Project Participants
   Sarah H. Wild, Stephen P. Fortmann, Santica M. Marcovina · 1997 · Arteriosclerosis Thrombosis and Vascular Biology
6. Rhesus Monkey Apolipoprotein(a)
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7. 5' control regions of the apolipoprotein(a) gene and members of the related plasminogen gene family.
   David P. Wade, John G. Clarke, Gisela E. Lindahl, Alexander C. Liu, Bernice R. Zysow, Kelli Meer, Katja Schwartz, Richard M. Lawn · 1993 · Proceedings of the National Academy of Sciences
8. AMG145, a Monoclonal Antibody Against Proprotein Convertase Subtilisin Kexin Type 9, Significantly Reduces Lipoprotein(a) in Hypercholesterolemic Patients Receiving Statin Therapy
   Nihar R. Desai, Payal Kohli, Robert Patrick Giugliano, Michelle L. O’Donoghue, Ransi M. Somaratne, Jing Zhou, Elaine B. Hoffman, Fannie Huang, William J. Rogers, Scott M. Wasserman et al. · 2013 · Circulation
9. 1 Mechanisms of physiological fibrinolysis
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10. Lipoprotein(a) as a risk factor for coronary artery disease
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11. Lipoprotein(a)
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12. The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
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13. Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a).
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14. Lipoprotein Lp(a) Excess and Coronary Heart Disease
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15. Molecular evolution and domain structure of plasminogen‐related growth factors (HGF/SF and HGF1/MSP)
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16. Lipoprotein(a) metabolism: Potential sites for therapeutic targets
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17. Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver
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18. IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans
    Nike Müller, Dominik Maria Schulte, Kathrin Türk, Sandra Freitag‐Wolf, Jochen Hampe, Rainald A. Zeuner, Johann Oltmann Schröder, Ioanna Gouni‐Berthold, Heiner K. Berthold, Wilhelm Krone et al. · 2015 · Journal of Lipid Research
19. Increased lipoprotein (a) levels as an independent risk factor for venous thromboembolism
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20. Lipoprotein(a) as a risk factor for atherosclerosis and thrombosis: mechanistic insights from animal models
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21. Toward the quiescent coronary plaque.
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22. Muscle-specific trk-related receptor with a kringle domain defines a distinct class of receptor tyrosine kinases.
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23. Correlation between lipoprotein(a) and aortic valve sclerosis assessed by echocardiography (the JMS Cardiac Echo and Cohort Study)
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24. S100A10, annexin A2, and annexin a2 heterotetramer as candidate plasminogen receptors
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25. Malondialdehyde modification of lipoprotein(a) produces avid uptake by human monocyte-macrophages.
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26. Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice.
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27. Antifibrinolytic activity of apolipoprotein(a) in vivo: Human apolipoprotein(a) transgenic mice are resistant to tissue plasminogen activator-mediated thrombolysis
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28. Homocysteine and Hemostasis: Pathogenetic Mechanisms Predisposing to Thrombosis
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29. Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease.
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30. Annexin II
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31. Lipoprotein(a) in Atherosclerotic Diseases: From Pathophysiology to Diagnosis and Treatment
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32. Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four Kringle domains with homology to hepatocyte growth factor
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33. A Polymorphism in the Protease-Like Domain of Apolipoprotein(a) Is Associated With Severe Coronary Artery Disease
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34. Lipoprotein(a) the Insurgent: A New Insight into the Structure, Function, Metabolism, Pathogenicity, and Medications Affecting Lipoprotein(a) Molecule
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35. Elevated serum lipoprotein(a) in subclinical hypothyroidism
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36. Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene.
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37. Hormonal regulation of serum Lp (a) levels. Opposite effects after estrogen treatment and orchidectomy in males with prostatic carcinoma.
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38. Oral Muvalaplin for Lowering of Lipoprotein(a)
    Stephen James Nicholls, Wei Ni, Grace M. Rhodes, Steven E. Nissen, Ann Marie Návar, Laura F. Michael, Axel Haupt, John Henry Krege · 2024 · JAMA
39. Cys4057 of apolipoprotein(a) is essential for lipoprotein(a) assembly.
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40. Inhibition of Plasminogen Activation by Lipoprotein(a)
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41. Molecular mechanisms of lipid disorders in nephrotic syndrome
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42. Prevalence of lipoprotein (a) [Lp(a)] excess in coronary artery disease
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43. Ancestry, Lipoprotein(a), and Cardiovascular Risk Thresholds
    Sotirios Tsimikas, Santica M. Marcovina · 2022 · Journal of the American College of Cardiology
44. Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA
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45. Structure-function relationships in apolipoprotein(a): insights into lipoprotein(a) assembly and pathogenicity
    Marlys L. Koschinsky, Santica M. Marcovina · 2004 · Current Opinion in Lipidology
46. Tamoxifen and estrogen lower circulating lipoprotein(a) concentrations in healthy postmenopausal women.
    D A Shewmon, John L. Stock, Clifford james Rosen, Kathleen M. Heiniluoma, Mireille Hogue, A Morrison, E M Doyle, THOMAS E. UKENA, V Weale, S Baker · 1994 · Arteriosclerosis and Thrombosis A Journal of Vascular Biology
47. Novel tocotrienols of rice bran modulate cardiovascular disease risk parameters of hypercholesterolemic humans
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48. Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells
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49. Polymorphism of human glycoprotein Ib alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. Structure/function implications.
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50. Lipoprotein(a) and inflammation in human coronary atheroma: association with the severity of clinical presentation
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51. Lipoprotein (a): Structure, Pathophysiology and Clinical Implications
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52. Rapid Angiographic Progression of Coronary Artery Disease in Patients With Elevated Lipoprotein(a)
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53. Frequency Distributions of Apolipoprotein(a) Kringle IV Repeat Alleles and Their Effects on Lipoprotein(a) Levels in Caucasian, Asian, and African Populations: The Distribution of Null Alleles Is Non-Random
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54. Lipoprotein(a)-Cholesterol and Coronary Heart Disease in the Framingham Heart Study
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55. Oxidized phospholipids in cardiovascular disease
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56. Apolipoprotein(a): expression and characterization of a recombinant form of the protein in mammalian cells
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57. The role of oxidized phospholipids in mediating lipoprotein(a) atherogenicity
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58. Shuffled domains in extracellular proteins
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59. A pentanucleotide repeat polymorphism in the 5' control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians.
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60. Spatio‐temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system
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61. Oxidation of lipoprotein Lp(a). A comparison with low-density lipoproteins
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62. Identification of a Family of Streptococcal Surface Proteins with Extremely Repetitive Structure
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63. Lipoprotein(a) impairs generation of plasmin by fibrin-bound tissue-type plasminogen activator. In vitro studies in a plasma milieu.
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64. Enzyme-linked immunoassay for Lp[a].
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65. Quantification of apo[a] and apoB in human atherosclerotic lesions.
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66. Interaction of recombinant apolipoprotein(a) and lipoprotein(a) with macrophages.
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67. Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans
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68. Effect of Ezetimibe Monotherapy on Plasma Lipoprotein(a) Concentrations in Patients with Primary Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
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69. Apolipoprotein(a) Induces Monocyte Chemotactic Activity in Human Vascular Endothelial Cells
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70. Lipoprotein (a), lipids, and lipoproteins in patients with rheumatoid arthritis.
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71. Expression of Three Recombinant Proteins Using Baculovirus Vectors in 23 Insect Cell Lines
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72. From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment
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73. Relation between number of apolipoprotein(a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature
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74. The apolipoprotein(a) gene resides on human chromosome 6q26?27, in close proximity to the homologous gene for plasminogen
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75. Cell surface assembly of lipoprotein(a) in primary cultures of baboon hepatocytes.
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76. Multicentre evaluation of combined prothrombotic defects associated with thrombophilia in childhood
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77. Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus.
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78. Lipoprotein[a] concentrations and apolipoprotein[a] phenotypes in Caucasians and African Americans. The CARDIA study.
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79. Hypofibrinolysis: A common, major cause of osteonecrosis
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80. Apolipoprotein(a) Gene Enhancer Resides within a LINE Element
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81. Interrelationships between plasma levels of plasminogen activator inhibitor, tissue plasminogen activator, lipoprotein (a), and established cardiovascular risk factors in a North Swedish population
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82. Serum Lp(a) lipoprotein concentrations in insulin dependent diabetic patients with microalbuminuria.
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83. Lipoprotein(a) Enhances the Expression of Intercellular Adhesion Molecule-1 in Cultured Human Umbilical Vein Endothelial Cells
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84. Des-γ-carboxy Prothrombin Is a Potential Autologous Growth Factor for Hepatocellular Carcinoma
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85. Lp(a) lipoprotein, IgG, IgA and IgM antibodies to Chlamydia pneumoniae and HLA class II genotype in early coronary artery disease
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86. Inhibition of Fibrinolysis by Lipoprotein(a)
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87. The endothelial cell tissue plasminogen activator receptor. Specific interaction with plasminogen.
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88. Lipoprotein(a) and ethnicities
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89. Failure of fluconazole prophylaxis to reduce mortality or the requirement of systemic amphotericin B therapy during treatment for refractory acute myeloid leukemia
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90. Expression of adhesion molecules by Lp(a): a potential novel mechanism for its atherogenicity
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91. Dror, a potential neurotrophic receptor gene, encodes a Drosophila homolog of the vertebrate Ror family of Trk-related receptor tyrosine kinases.
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92. Lipoprotein (a) and stroke: Table 1
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93. A comparison of the PROCAM and Framingham point-scoring systems for estimation of individual risk of coronary heart disease in the Second Northwick Park Heart Study
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94. The apolipoprotein(a) gene is regulated by sex hormones and acute–phase inducers in YAC transgenic mice
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95. Sequence polymorphisms in the apolipoprotein (a) gene. Evidence for dissociation between apolipoprotein(a) size and plasma lipoprotein(a) levels.
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96. Lipoprotein(a): An independent, genetic, and causal factor for cardiovascular disease and acute myocardial infarction
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97. Familial hypercholesterolemia and elevated lipoprotein(a): double heritable risk and new therapeutic opportunities
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98. Effect of Aspirin Treatment on Serum Concentrations of Lipoprotein(a) in Patients with Atherosclerotic Diseases
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99. Geriatric depression and vascular diseases: what are the links?
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100. Intracellular maturation of apolipoprotein[a] and assembly of lipoprotein[a] in primary baboon hepatocytes.
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