Gene losses in human tumours

Mutation and cancer: statistical study of retinoblastoma

Knudson, A. G. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.4.820 · Cited by 7,612

Genetic Alterations during Colorectal-Tumor Development

Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Smits, A. M. M., & Bos, J. L. (1988) · New England Journal of Medicine · doi:10.1056/nejm198809013190901 · Cited by 6,728

Localization of the gene for familial adenomatous polyposis on chromosome 5

Bodmer, W. F., Bailey, C. J., Bodmer, J., Bussey, H. J. R., Ellis, A., Gorman, P., Lucibello, F. C., Murday, V. A., Rider, S. H., Scambler, P., et al. (1987) · Nature · doi:10.1038/328614a0 · Cited by 1,390

Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC

Harbour, J. W., Lai, S.-L., Whang-Peng, J., Gazdar, A. F., Minna, J. D., & Kaye, F. J. (1988) · Science · doi:10.1126/science.2838909 · Cited by 902

Gene for von Recklinghausen Neurofibromatosis Is in the Pericentromeric Region of Chromosome 17

Barker, D., Wright, E., Nguyen, K., Cannon, L., Fain, P., Goldgar, D., Bishop, D. T., Carey, J., Baty, B., Kivlin, J., et al. (1987) · Science · doi:10.1126/science.3107130 · Cited by 695

Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

Seizinger, B. R., Rouleau, G. A., Ozelius, L. J., Lane, A. H., Farmer, G. E., Lamiell, J. M., Haines, J., Yuen, J. W. M., Collins, D., Majoor-Krakauer, D., et al. (1988) · Nature · doi:10.1038/332268a0 · Cited by 662

Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation

Cohen, A. J., Li, F. P., Berg, S., Marchetto, D. J., Tsai, S., Jacobs, S. C., & Brown, R. S. (1979) · New England Journal of Medicine · doi:10.1056/nejm197909133011107 · Cited by 645

Inactivation of the Retinoblastoma Susceptibility Gene in Human Breast Cancers

Lee, E. Y.-H. P., To, H., Shew, J.-Y., Bookstein, R., Scully, P., & Lee, W.-H. (1988) · Science · doi:10.1126/science.3388033 · Cited by 581

Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.

Yokota, J., Wada, M., Shimosato, Y., Terada, M., & Sugimura, T. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9252 · Cited by 480

Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer

Naylor, S. L., Johnson, B. E., Minna, J. D., & Sakaguchi, A. Y. (1987) · Nature · doi:10.1038/329451a0 · Cited by 467

Common Inheritance of Susceptibility to Colonic Adenomatous Polyps and Associated Colorectal Cancers

Cannon-Albright, L. A., Skolnick, M. H., Bishop, D. T., Lee, R. G., & Burt, R. W. (1988) · New England Journal of Medicine · doi:10.1056/nejm198809013190902 · Cited by 460

A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10

Mathew, C. G. P., Chin, K. S., Easton, D. F., Thorpe, K., Carter, C., Liou, G. I., Fong, S.-L., Bridges, C. D. B., Haak, H., Kruseman, A. C. N., et al. (1987) · Nature · doi:10.1038/328527a0 · Cited by 440

Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage

Simpson, N. E., Kidd, K. K., Goodfellow, P. J., McDermid, H., Myers, S., Kidd, J. R., Jackson, C. E., Duncan, A. M. V., Farrer, L. A., Brasch, K., et al. (1987) · Nature · doi:10.1038/328528a0 · Cited by 425

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.

Escot, C., Theillet, C., Lidereau, R., Spyratos, F., Champeme, M. H., Gest, J., & Callahan, R. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.13.4834 · Cited by 412

Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene

Seizinger, B. R., Rouleau, G. A., Ozelius, L. J., Lane, A. H., Faryniarz, A. G., Chao, M. V., Huson, S., Korf, B. R., Parry, D. M., Pericak-Vance, M. A., et al. (1987) · Cell · doi:10.1016/0092-8674(87)90534-4 · Cited by 368

Loss of a Harvey ras allele in sporadic Wilms' tumour

Reeve, A. E., Housiaux, P. J., Gardner, R. J. M., Chewings, W. E., Grindley, R. M., & Millow, L. J. (1984) · Nature · doi:10.1038/309174a0 · Cited by 328

Molecular Analysis of the Short Arm of Chromosome 3 in Small-Cell and Non-Small-Cell Carcinoma of the Lung

Brauch, H., Johnson, B., Hovis, J., Yano, T., Gazdar, A., Pettengill, O. S., Graziano, S., Sorenson, G. D., Poiesz, B. J., Minna, J., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198710293171803 · Cited by 327

Deletion of genes on chromosome 1 in endocrine neoplasia

Mathew, C. G. P., Smith, B. A., Thorpe, K., Wong, Z., Royle, N. J., Jeffreys, A. J., & Ponder, B. A. J. (1987) · Nature · doi:10.1038/328524a0 · Cited by 259

Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors.

Schroeder, W. T., Chao, L. Y., Dao, D., et al. (1987) · PubMed · Cited by 214

Deletion mapping of a locus on human chromosome 22 involved in the oncogenesis of meningioma.

Dumanski, J. P., Carlbom, E., Collins, V. P., & Nordenskjöld, M. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9275 · Cited by 214

Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas.

Theillet, C. G., Lidereau, R., Escot, C., Hutzell, P., Brunet, M., Gest, J., Schlom, J., & Callahan, R. (1986) · PubMed · Cited by 213

The analysis of malignancy by cell fusion: the position in 1988.

Harris, H. (1988) · PubMed · Cited by 171

Loss of constitutional heterozygosity in colon carcinoma from patients with familial polyposis coli

Okamoto, M., Sasaki, M., Sugio, K., Sato, C., Iwama∥, T., Ikeuchi, T., Tonomura, A., Sasazuki, T., & Miyaki, M. (1988) · Nature · doi:10.1038/331273a0 · Cited by 156

Structure of the I(2)gl gene of Drosophila and delimitation of its tumor suppressor domain

Jacob, L. R., Opper, M., Metzroth, B., Phannavong, B., & Mechler, B. M. (1987) · Cell · doi:10.1016/0092-8674(87)90217-0 · Cited by 106

Retinoblastoma and the progression of tumor genetics

Hansen, M. F., & Cavenee, W. K. (1988) · Trends in Genetics · doi:10.1016/0168-9525(88)90134-5 · Cited by 76

Recessive mechanisms of malignancy

Green, A. R. (1988) · British Journal of Cancer · doi:10.1038/bjc.1988.176 · Cited by 57

A genetic model for colorectal tumorigenesis

Fearon, E. R., & Vogelstein, B. (1990) · Cell · doi:10.1016/0092-8674(90)90186-i · Cited by 12,132

Allelotype of Colorectal Carcinomas

Vogelstein, B., Fearon, E. R., Kern, S. E., Hamilton, S. R., Preisinger, A. C., Nakamura, Y., & White, R. (1989) · Science · doi:10.1126/science.2565047 · Cited by 1,304

Allele losses in the region 17q12–21 in familial breast and ovarian cancer involve the wild–type chromosome

Smith, S. A., Easton, D. F., Evans, D. G. R., & Ponder, B. A. J. (1992) · Nature Genetics · doi:10.1038/ng1092-128 · Cited by 411

Li-Fraumeni syndrome – a molecular and clinical review

Varley, J., Evans, D., & Birch, J. (1997) · British Journal of Cancer · doi:10.1038/bjc.1997.328 · Cited by 358

Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus

Wittbrodt, J., Adam, D., Malitschek, B., Mäueler, W., Raulf, F., Telling, A., Robertson, S. M., & Schartl, M. (1989) · Nature · doi:10.1038/341415a0 · Cited by 337