Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1
DOI 10.1038/35047014
Cited by (355)
Items 201–300 of 355
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- A negative-feedback loop regulating ERK1/2 activation and mediated by RasGPR2 phosphorylationJinqi Ren, Aaron A. Cook, Wolfgang Bergmeier, John Sondek · 2016 · Biochemical and Biophysical Research Communications
- The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterningMichael C Armstrong, Yannic R Weiß, Lila E Hoachlander-Hobby, Ankit Roy, Ilaria Visco, Alison B. Moe, Adriana E. Golding, Scott D. Hansen, William M. Bement, Peter Bieling · 2025 · The EMBO Journal
- Distinct CED-10/Rac1 domains confer context-specific functions in developmentSteffen Nørgaard, Shuer Deng, Wei Jie Cao, Roger Pocock · 2018 · PLoS Genetics
- A Minimal Rac Activation Domain in the Unconventional Guanine Nucleotide Exchange Factor Dock180Xin Wu, Sekar Ramachandran, Miao-Chong Joy Lin, Richard A. Cerione, Jon W. Erickson · 2010 · Biochemistry
- The Rac-GEF Tiam1 controls integrin-dependent neutrophil responsesKirsti Hornigold, Martin J. Baker, Polly A. Machin, Stephen A. Chetwynd, Anna‐Karin Johnsson, Chiara Pantarelli, Priota Islam, Melanie Stammers, Laraine Crossland, David Oxley et al. · 2023 · Frontiers in Immunology
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- Targeting guanine nucleotide exchange factors for novel cancer drug discoverySahar F. Bannoura, Husain Yar Khan, Md. Hafiz Uddin, Ramzi M. Mohammad, Boris Pasche, Asfar Sohail Azmi · 2024 · Expert Opinion on Drug Discovery
- New insights into the molecular mechanism of the Rab GTPase Sec4p activationFábio C. Rinaldi, Michael S. Packer, Ruth Collins · 2015 · BMC Structural Biology
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