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Cited by 454

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Reprogramming of genome function through epigenetic inheritance

Open access
Surani, M. Azim·2001·Nature

Abstract

Most cells contain the same set of genes and yet they are extremely diverse in appearance and functions. It is the selective expression and repression of genes that determines the specific properties of individual cells. Nevertheless, even when fully differentiated, any cell can potentially be reprogrammed back to totipotency, which in turn results in re-differentiation of the full repertoire of adult cells from a single original cell of any kind. Mechanisms that regulate this exceptional genomic plasticity and the state of totipotency are being unravelled, and will enhance our ability to manipulate stem cells for therapeutic purposes.

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Metadata

Authors
Surani, M. A.
Venue
Nature
Published
2001-11
Volume
414
Issue
6859
Pages
122-128
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W2170940855
Cited by
454
References
4
FWCI
12.81
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Reprogramming of genome function through epigenetic inheritance. https://app.cochat.ai/papers/10.1038/35102186
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Surani, M. A. (2001). Reprogramming of genome function through epigenetic inheritance. Nature. https://doi.org/10.1038/35102186

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.