Erratum: Positional cloning of a global regulator of anterior–posterior patterning in mice

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

Brünger, A. T. (1992) · Medical Entomology and Zoology · Cited by 3,439 · see citing works

Data collection and processing

Turkenburg, J. P., & Brady, L. (1999) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444999013761 · Cited by 115 · see citing works

Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

Cao, R., Wang, L., Wang, H., Xia, L., Erdjument-Bromage, H., Tempst, P., Jones, R. S., & Zhang, Y. (2002) · Science · doi:10.1126/science.1076997 · Cited by 3,775 · see citing works

Histone Methyltransferase Activity of a Drosophila Polycomb Group Repressor Complex

Müller, J., Hart, C. M., Francis, N. J., Vargas, M. L., Sengupta, A. K., Wild, B., Miller, E., O’Connor, M. B., Kingston, R. E., & Simon, J. A. (2002) · Cell · doi:10.1016/s0092-8674(02)00976-5 · Cited by 1,553 · see citing works

Role of Histone H3 Lysine 27 Methylation in X Inactivation

Plath, K., Fang, J., Mlynarczyk‐Evans, S., Cao, R., Worringer, K. A., Wang, H., de la Cruz, C. C., Otte, A. P., Panning, B., & Zhang, Y. (2003) · Science · doi:10.1126/science.1084274 · Cited by 1,190 · see citing works

Stem Cells and Cancer

Valk-Lingbeek, M. E., Bruggeman, S. W. M., & van Lohuizen, M. (2004) · Cell · doi:10.1016/j.cell.2004.08.005 · Cited by 743 · see citing works

Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes

Silva, J., Mak, W., Zvetkova, I., Appanah, R., Nesterova, T. B., Webster, Z., Peters, A. H. F. M., Jenuwein, T., Otte, A. P., & Brockdorff, N. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00068-6 · Cited by 638 · see citing works

Histone Methylation Regulates Memory Formation

Gupta, S., Kim, S. Y., Artis, S., Molfese, D. L., Schumacher, A., Sweatt, J. D., Paylor, R. E., & Lubin, F. D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3732-09.2010 · Cited by 562 · see citing works

Epigenetic balance of gene expression by Polycomb and COMPASS families

Piunti, A., & Shilatifard, A. (2016) · Science · doi:10.1126/science.aad9780 · Cited by 524 · see citing works

Epigenetic regulation of brain region-specific microglia clearance activity

Ayata, P., Badimon, A., Strasburger, H. J., Duff, M. K., Montgomery, S. E., Loh, Y.-H. E., Ebert, A., Pimenova, A. A., Ramirez, B. R., Chan, A. T., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0192-3 · Cited by 460 · see citing works

Reprogramming of genome function through epigenetic inheritance

Surani, M. A. (2001) · Nature · doi:10.1038/35102186 · Cited by 453 · see citing works

Chromatin repressive complexes in stem cells, development, and cancer

Laugesen, A., & Helin, K. (2014) · Cell stem cell · doi:10.1016/j.stem.2014.05.006 · Cited by 352 · see citing works

The Murine Polycomb Group Protein Eed Is Required for Global Histone H3 Lysine-27 Methylation

Montgomery, N. D., Yee, D., Chen, A., Kalantry, S., Chamberlain, S. J., Otte, A. P., & Magnuson, T. (2005) · Current Biology · doi:10.1016/j.cub.2005.04.051 · Cited by 345 · see citing works

Imprinted X inactivation maintained by a mouse Polycomb group gene

Wang, J., Mager, J., Chen, Y., Schneider, E., Cross, J. C., Nagy, A., & Magnuson, T. (2001) · Nature Genetics · doi:10.1038/ng574 · Cited by 338 · see citing works

Polycomb Repressive Complex 2 Is Dispensable for Maintenance of Embryonic Stem Cell Pluripotency

Chamberlain, S. J., Yee, D., & Magnuson, T. (2008) · Stem Cells · doi:10.1634/stemcells.2008-0102 · Cited by 338 · see citing works

Bivalent histone modifications in early embryogenesis

Vastenhouw, N. L., & Schier, A. F. (2012) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2012.03.009 · Cited by 297 · see citing works

Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and CancerPreprint

Laugesen, A., Højfeldt, J. W., & Helin, K. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a026575 · Cited by 214 · see citing works

Mitotically Stable Association of Polycomb Group Proteins Eed and Enx1 with the Inactive X Chromosome in Trophoblast Stem Cells

Mak, W., Baxter, J., Silva, J., Newall, A. E. T., Otte, A. P., & Brockdorff, N. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00892-8 · Cited by 209 · see citing works

Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression

Akasaka, T., van Lohuizen, M., van der Lugt, N. M. T., Mizutani-Koseki, Y., Kanno, M., Taniguchi, M., Vidal, M., Alkema, M. J., Berns, A. J. M., & Koseki, H. (2001) · Development · doi:10.1242/dev.128.9.1587 · Cited by 185 · see citing works

X-chromosome inactivation: closing in on proteins that bind Xist RNA

Brockdorff, N. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(02)02717-8 · Cited by 142 · see citing works

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

Majewski, I. J., Ritchie, M. E., Phipson, B., Corbin, J., Pakusch, M., Ebert, A., Busslinger, M., Koseki, H., Hu, Y., Smyth, G. K., et al. (2010) · Blood · doi:10.1182/blood-2009-12-260760 · Cited by 135 · see citing works

The Yin and Yang of YY1 in the nervous system

He, Y., & Casaccia‐Bonnefil, P. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05486.x · Cited by 132 · see citing works

Involvement of the Polycomb-group geneRing1Bin the specification of the anterior-posterior axis in mice

Suzuki, M., Mizutani-Koseki, Y., Fujimura, Y., Miyagishima, H., Kaneko, T., Takada, Y., Akasaka, T., Tanzawa, H., Takihara, Y., Nakano, M., et al. (2002) · Development · doi:10.1242/dev.129.18.4171 · Cited by 94 · see citing works

HIV-1 Nef Mimics an Integrin Receptor Signal that Recruits the Polycomb Group Protein Eed to the Plasma Membrane

Witte, A. V., Laffert, B., Rosorius, O., Lischka, P., Blume, K., Galler, G. R., Stilper, A., Willbold, D., D’Aloja, P., Sixt, M., et al. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00004-8 · Cited by 79 · see citing works

The Vertebral Column

Rice, D. P. C., & Dietrich, S. (2008) · Wiley eBooks · doi:10.1002/9780470090121.ch15 · Cited by 69 · see citing works

Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes

Takada, Y., Isono, K., Shinga, J., Turner, J. M. A., Kitamura, H., Ohara, O., Watanabe, G., Singh, P. B., Kamijo, T., Jenuwein, T., et al. (2007) · Development · doi:10.1242/dev.02747 · Cited by 65 · see citing works

EED and KDM6B Coordinate the First Mammalian Cell Lineage Commitment To Ensure Embryo Implantation

Saha, B., Home, P., Ray, S. S., Larson, M. A., Paul, A., Rajendran, G., Behr, B. R., & Paul, S. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.00069-13 · Cited by 60 · see citing works

Regulating Methylation at H3K27: A Trick or Treat for Cancer Cell Plasticity

Das, P., & Taube, J. H. (2020) · Cancers · doi:10.3390/cancers12102792 · Cited by 57 · see citing works

FGF Signalling Regulates Chromatin Organisation during Neural Differentiation via Mechanisms that Can Be Uncoupled from Transcription

Patel, N. S., Rhinn, M., Semprich, C. I., Halley, P. A., Dollé, P., Bickmore, W. A., & Storey, K. G. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003614 · Cited by 56 · see citing works

Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus

Liu, P., Xu, Y., Dai, S., Du, H., Wang, Y., Li, X., Teng, Z., & Liu, C. (2019) · Stem Cell Reports · doi:10.1016/j.stemcr.2019.05.010 · Cited by 41 · see citing works

PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

Prokopuk, L., Stringer, J. M., Hogg, K., Elgass, K., & Western, P. S. (2017) · Epigenetics & Chromatin · doi:10.1186/s13072-017-0113-9 · Cited by 38 · see citing works

Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type–specific cancer genes in leukemia

Sauvageau, M., Miller, M., Lemieux, S., Lessard, J. A., Hébert, J., & Sauvageau, G. (2007) · Blood · doi:10.1182/blood-2007-07-098236 · Cited by 35 · see citing works

Polycomb Group Protein-Mediated Histone Modifications during Cell Differentiation

Khan, A. A., Lee, A., & Roh, T. (2015) · Epigenomics · doi:10.2217/epi.14.61 · Cited by 34 · see citing works

Loss of microglial EED impairs synapse density, learning, and memory

Wang, Y.-Y., Deng, Y.-S., Dai, S.-K., Mi, T.-W., Li, R.-Y., Liu, P.-P., Liu, C., He, B.-D., He, X.-C., Du, H.-Z., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01576-w · Cited by 32 · see citing works

Evolutionarily conserved anterior expansion of the central nervous system promoted by a common PcG-Hox program

Salmani, B. Y., Cobeta, I., Rakar, J., Bauer, S., Curt, J. R., Starkenberg, A., & Thor, S. (2018) · Development · doi:10.1242/dev.160747 · Cited by 32 · see citing works

An Allelic Series of Mutations in theKit ligandGene of Mice. II. Effects of Ethylnitrosourea-InducedKitlPoint Mutations on Survival and Peripheral Blood Cells ofKitlSteelMice

Rajaraman, S., Davis, W. S., Mahakali-Zama, A., Evans, H. K., Russell, L. B., & Bedell, M. A. (2002) · Genetics · doi:10.1093/genetics/162.1.341 · Cited by 28 · see citing works

Uncovering the uncharacterized and unexpected: Unbiased phenotype‐driven screens in the mouse

Caspary, T., & Anderson, K. V. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20853 · Cited by 28 · see citing works

Transcriptional Repression by XPc1, a New Polycomb Homolog in Xenopus laevis Embryos, Is Independent of Histone Deacetylase

Strouboulis, J., Damjanovski, S., Vermaak, D., Meric, F., & Wolffe, A. P. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.3958 · Cited by 28 · see citing works

Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System

Liu, P., Xu, Y., Teng, Z., & Liu, C. (2017) · The Neuroscientist · doi:10.1177/1073858417747839 · Cited by 27 · see citing works

An Allelic Series of Mutations in the Kit ligand Gene of Mice. I. Identification of Point Mutations in Seven Ethylnitrosourea-Induced KitlSteel Alleles

Rajaraman, S., Davis, W. S., Mahakali-Zama, A., Evans, H. K., Russell, L. B., & Bedell, M. A. (2002) · Genetics · doi:10.1093/genetics/162.1.331 · Cited by 27 · see citing works

Epigenetic Regulation of Stem Cells

Wutz, A. (2013) · Advances in experimental medicine and biology · doi:10.1007/978-94-007-6621-1_17 · Cited by 25 · see citing works

Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

Stringer, J. M., Forster, S. C., Qu, Z., Prokopuk, L., O’Bryan, M. K., Gardner, D. K., White, S. J., Adelson, D. L., & Western, P. S. (2018) · BMC Biology · doi:10.1186/s12915-018-0569-5 · Cited by 23 · see citing works

Misexpression of Polycomb-Group Proteins in Xenopus Alters Anterior Neural Development and Represses Neural Target Genes

Yoshitake, Y., Howard, T. L., Christian, J. L., & Hollenberg, S. M. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9473 · Cited by 23 · see citing works

Loss of Late Primitive Streak Mesoderm and Interruption of Left–Right Morphogenesis in the Ednrbs-1Acrg Mutant Mouse

Welsh, I. C., & O’Brien, T. P. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9814 · Cited by 22 · see citing works

Hypomorphic mutation of the mouse Huntington’s disease gene orthologue

Murthy, V., Tebaldi, T., Yoshida, T., Erdin, S., Calzonetti, T., Vijayvargia, R., Tripathi, T., Kerschbamer, E., Seong, I. S., Quattrone, A., et al. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1007765 · Cited by 17 · see citing works

Chromatin Accessibility Mapping Identifies Mediators of Basal Transcription and Retinoid-Induced Repression of OTX2 in Medulloblastoma

Wortham, M., Guo, C., Zhang, M., Song, L., Lee, B., Iyer, V. R., Furey, T. S., Crawford, G. E., Yan, H., & He, Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107156 · Cited by 15 · see citing works

HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformations in genetically wildtype offspring

Xue, S., Ly, T. T. N., Vijayakar, R. S., Chen, J., Ng, J. D., Mathuru, A. S., Magdinier, F., & Reversade, B. (2022) · Nature Communications · doi:10.1038/s41467-022-31185-8 · Cited by 13 · see citing works

Developmental Patterning as a Quantitative Trait: Genetic Modulation of the Hoxb6 Mutant Skeletal Phenotype

Kappen, C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0146019 · Cited by 13 · see citing works

Low complexity domains, condensates, and stem cell pluripotency

Vodnala, M., Choi, E., & Fong, Y. W. (2021) · World Journal of Stem Cells · doi:10.4252/wjsc.v13.i5.416 · Cited by 9 · see citing works

A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB

Cherney, R. E., Mills, C. A., Herring, L. E., Braceros, A. K., & Calabrese, J. M. (2023) · Biology Open · doi:10.1242/bio.059955 · Cited by 9 · see citing works

X-ray-induced deletion complexes in embryonic stem cells on mouse chromosome 15

Chick, W. S. H., Mentzer, S. E., Carpenter, D. A., Rinchik, E. M., Johnson, D. K., & You, Y. (2005) · Mammalian Genome · doi:10.1007/s00335-005-0011-5 · Cited by 9 · see citing works

Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes

Salmani, B. Y., Balderson, B., Bauer, S., Ekman, H., Starkenberg, A., Perlmann, T., Piper, M., Mikael Bodén, A., & Thor, S. (2022) · Development · doi:10.1242/dev.200076 · Cited by 7 · see citing works

An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14

Hagarman, J. A., & O’Brien, T. P. (2009) · genesis · doi:10.1002/dvg.20510 · Cited by 5 · see citing works

An essential role for Polycomb Repressive Complex 2 in the mouse ovary

Prokopuk, L., Jarred, E. G., Blücher, R. O., McLaughlin, E. A., Stringer, J. M., & Western, P. S. (2022) · Reproduction · doi:10.1530/rep-21-0361 · Cited by 5 · see citing works

Physical Localization of the Mesoderm Development (mesd) Functional Region

Wines, M. E., Shi, Y., Lindor, M., & Holdener, B. C. (2000) · Genomics · doi:10.1006/geno.2000.6264 · Cited by 5 · see citing works

Polycomb repressive complex 2 regulates sexual development in Neurospora crassa

Deaven, A. M., Ameri, A. J., & Lewis, Z. (2025) · mBio · doi:10.1128/mbio.01505-25 · Cited by 4 · see citing works

Nucleotide substitutions revealing specific functions of Polycomb group genes

Bajusz, I., Sípos, L., & Pirity, M. K. (2015) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2015.01.007 · Cited by 4 · see citing works

Polycomb in female reproductive health: patterning the present and programming the future

Jarred, E. G., & Western, P. S. (2024) · Reproduction Fertility and Development · doi:10.1071/rd24152 · Cited by 1 · see citing works

Mouse Models of Epigenetic Inheritance: Classification, Mechanisms, and Experimental Strategies

Mao, S., Li, Y., Liu, B., & Chi, T. H. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805388-1.00015-8 · Cited by 1 · see citing works

Chromatin-Modifying Factors and Transcriptional Regulation During Development

Bultman, S. J., Montgomery, N. D., & Magnuson, T. (2004) · Elsevier eBooks · doi:10.1016/b978-012436643-5/50015-8 · Cited by 1 · see citing works

Mechanism of Functional Alterations in Hematopoietic Stem Cell Aging

Morita, Y. (2014) · Else Kröner-Fresenius Symposia · doi:10.1159/000366570

Hematopoietic Stem Cell Aging and Fate Decision

Illing, A., & Ju, Z. (2010) · Else Kröner-Fresenius Symposia · doi:10.1159/000312645

Message control in developmental transitions; deciphering chromatin's role using zebrafish genomics

Stapel, L. C., & Vastenhouw, N. L. (2013) · Briefings in Functional Genomics · doi:10.1093/bfgp/elt045

Genetic analysis of the exed region in mouse

Kendall, S. K., Strong, S. J., Litman, R. T., Litman, G. W., & Magnuson, T. (2000) · genesis · doi:10.1002/1526-968x(200008)27:4

The Role of Polycomb Group Proteins in Hematopoietic Stem Cell (HSC) Self-Renewal and Leukemogenesis

van den Boom, V., Schepers, H., Brouwers-Vos, A. Z., & Schuringa, J. J. (2014) · Epigenetics and human health · doi:10.1007/978-3-642-45198-0_6

The Dynamics of Polycomb Complexes

Palacios, D. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6380-5_12

Genomic imprinting

Arney, K. L., Erhardt, S., & Surani, M. A. (2002) · Advances in developmental biology and biochemistry · doi:10.1016/s1569-1799(02)12029-6

Chromatin and transcription

Morse, R. H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-814809-9.00009-3

SP1 antagonizes H3K27me3 to shape chromatin landscapes for RNA polymerase II recruitment during gastrulation

Shen, X., Wen, Y., Tang, X., Liu, Y. J., Li, W., Chen, W.-Z., Yang, S., Wang, L., Yang, H., Liu, K., et al. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag305

Positional cloning of a global regulator of anterior–posterior patterning in mice

Schumacher, A., Faust, C. J., & Magnuson, T. (1996) · Nature · doi:10.1038/383250a0 · Cited by 292 · see citing works

[Genetic mechanisms of mouse anterior-posterior patterning].

Matsuo, I., & Kimura-Yoshida, C. (2005) · PubMed

The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs

Yamamoto, M. (2012) · Kyoto University Research Information Repository (Kyoto University)

Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product.

Xu, X., Yang, W., Jackowski, S., & Rock, C. O. (1996) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41505-0 · Cited by 15 · see citing works

A homeotic gene cluster patterns the anteroposterior body axis of the nematode C. elegans

Wang, B. (1993) · eScholarship (California Digital Library)