Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
Lowell, Bradford B., S-Susulic, Vedrana, Hamann, Andreas, Lawitts, Joel A., Himms-Hagen, Jean, Boyer, Bert B., Kozak, Leslie P., Flier, Jeffrey S.·1993·Nature
DOI 10.1038/366740a0
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- Hormnios tireideos, UCPs e termogneseAntonio Carlos Bianco · 2000 · Arquivos Brasileiros de Endocrinologia & Metabologia
- Le tissu adipeux brun humainDaniel Ricquier · 2012 · Cahiers de Nutrition et de Diététique
- The future of feed intake regulation researchClifton A. Baile, Mary Anne Della‐Fera · 2001 · Journal of Animal Science
- Genetics of visceral obesity and insulin resistance: relationship to non-insulin-dependent diabetes mellitusLeif Groop · 1998 · Growth Hormone & IGF Research
- From animals in the service of nutrition… to the potential of biotechnologyJudith Hall · 1997 · British Journal Of Nutrition
- A Regulatory Pathway of Thermogenesis in Brown Fat Through Retinoic AcidGeorge Wolf · 2009 · Nutrition Reviews
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- Thermogenesis and the Metabolic SyndromeMaria Luisa Bonet, Catalina Picó, Andreu Palou · 2005 · Elsevier eBooks
- Role of PPARγ in adipocyte recruitment and thermogenesisEdoardo Dalla Nora, Sarah Louise Gray, Antonio Vidal‐Puig · 2007 · Expert Review of Endocrinology & Metabolism
- Thermoregulatory consequences of starvation and digestion in birdsMirja Laurila · 2005
- Anti-obesity activity1H. Gerhard Vogel, Wolfgang H. Vogel, Bernward A. Schölkens, Jürgen Sandow, Günter A. Müller, Wolfgang F. Vogel · 2002 · Springer eBooks
- Appetite Regulation and ThermogenesisEleftheria Maratos–Flier · 2010 · Elsevier eBooks
- p27Kip1 Deficiency Impairs Brown Adipose Tissue Function Favouring Fat Accumulation in MiceIgnacio Colón-Mesa, Neira Sáinź, Patricia Corrales, María Collantes, Philipp Kaldis, José Alfredo Martínez, Gema Medina‐Gómez, María Jesús Moreno-Aliaga, Xavier Escoté · 2023 · International Journal of Molecular Sciences
- FAcTs on fire: Exploring thermogenesisAmanda Rodríguez-Díaz, Carlos Diéguez, Miguel López, Óscar Freire-Agulleiro · 2025 · Advances in genetics
- Functional Anatomy of the ‘Adipose Organ’Saverio Cinti · 2007 · Springer eBooks
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- Brown Adipose Tissue: Function and DevelopmentDaniel Ricquier · 2012 · Springer eBooks
- Disorders of the Body MassPatricia A. Donohoue, Omar Ali · 2013 · Elsevier eBooks
- Brown Adipose Tissue Energy MetabolismYuan Lü · 2019 · IntechOpen eBooks
- Stimuler les tissus adipeux bruns et beiges : un levier thérapeutique ?Damien Lagarde, Rémi Montané, Isabelle Ader, Louis Casteilla, Audrey Carrière · 2021 · Médecine des Maladies Métaboliques
- The Adipose OrganSaverio Cinti · 2019 · Endocrinology
- Benefits of a fixed-dose combination of standardized P. mume extract with choline on adipose tissue mitochondrial metabolic activity and pancreatic β-islet secretory capacity in miceEleftheria C. Sagiadinou, Eleni A. Karavia, Eva Xepapadaki, Evangelia Zvintzou, Aikaterini Hatziri, Dimitra Sotiria Karampela, Panagiota C. Giannopoulou, Dionysios J. Papachristou, George D. Panayiotakopoulos, Kyriakos E. Kypreos · 2022 · Phytomedicine Plus
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- Energy and ATP: Costs and benefitsJ. P. Flatt · 1999 · Springer eBooks
- Genetic Susceptibility of Rodents to Diet-Induced ObesityJoanne Allison Harrold · 2001 · Springer eBooks
- ADIPOSE TISSUE AS AN ENDOCRINE ORGAN: PATHOPHYSIOLOGICAL AND THERAPEUTIC IMPLICATIONSMaritza Pérez-Mayorga · 2007 · Redalyc (Universidad Autónoma del Estado de México)
- New Obesity Targets: Molecular-Genetic and Transgenic ApproachesDavid E. Moller, Lex H.T. Van der Ploeg · 2000 · Handbook of experimental pharmacology
- Souris transgéniques: un tour d'horizonCharles Babinet · 1997 · Annales de l Institut Pasteur / Actualités
- Construction and characterization of novel expression vectors for genetic adipose tissue ablationDuck Sung Ko, Woong Hwan Choi, Chul Geun Kim · 1998 · Korean Journal of Biological Sciences
- Wherefore art thou brown fat?Roland T. Jung · 1994 · Clinical Endocrinology
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- Alcohol dehydrogenase activity in mouse brown adipose tissue.Muralidhara Dv, M. Desautels · 1996 · PubMed
- Candidate genes for obesity and related phenotypesMichael M. Swarbrick · 2002 · UWA Profiles and Research Repository (UWA)
- Grasa pardaMoisés Castellá, Francesc Villarroya · 2023 · Medicina Clínica
- Brown fatMoisés Castellá, Francesc Villarroya · 2023 · Medicina Clínica (English Edition)
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- Cellular thermogenic mechanisms : a comparative study of brown adipose tissue and skeletal muscleAnita Matthias · 1995 · UTAS Research Repository
- Central Integration of Environmental and Endogenous Signals Important in the Regulation of Food Intake and Energy ExpenditureIosif Kelesidis, Theodoros Kelesidis, Christos Socrates Mantzoros · 2009 · Humana Press eBooks
- Insulin Sensitivity and the Onset of Hyperphagia in Fatty RatsHoliday A. Durham · 2004
- L’organo endocrino adiposoSaverio Cinti · 2006 · L Endocrinologo
- Transgenic Animal Models and the Metabolic SyndromeSylvie Franckhauser, Fátima Bosch · 2005 · Elsevier eBooks
- Role of Energy Expenditure in Regulation of Energy HomeostasisEric Scott Bachman · 2006 · Humana Press eBooks
- Fischer 344 rats are the same weight but are fatter than rats fed a high fat dietRachel A. Schemmel, Krystyna M. Kras, Nelle Cotten, Kazuharu Suzuki, B.K. Sharma, M.J. VandeHaar · 1996 · Nutrition Research
- The culture and differentiation of human pluripotent cells into brown and white adipocytesRobert T. Schinzel · 2012 · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver
- Browning of Adipose OrganSaverio Cinti · 2014 · Springer eBooks
- The role of stem cells in adipose tissue remodeling.Holden · 2014 · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville)
- Hormone-Sensitive Lipase - New roles in adipose tissue biologyKristoffer Ström · 2008 · Lund University Publications (Lund University)
- Tissu adipeux brun : fonction et développementDaniel Ricquier · 2013 · Springer eBooks
- Exploratory Studies on Biomarkers: An Example Study on Brown Adipose TissueMasahiro Watanabe, Naoshi Yamazaki, Masatoshi Kataoka, Yasuo Shinohara · 2007 · IEEJ Transactions on Electronics Information and Systems
- Clues to obesity from miceJohn Bignall · 1994 · The Lancet
- La proteína desacoplante mitocondrial UCP3, ¿un nuevo actor en el metabolismo muscular de los ácidos grasos?Francesc Villarroya · 2003 · Clínica e Investigación en Arteriosclerosis
- Identification of TRPV4 as a Regulator of Adipose Oxidative Metabolism, Inflammation and Energy Homeostasis by a Chemical Biology ApproachYe Li · 2013 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
- Insulin Resistance, Dyslipidemia, Type 2 Diabetes Mellitus and Metabolic SyndromeUndurti Narasimha Das · 2011 · Springer eBooks
- 4 New directions in fat researchPeter Robin Shepherd · 1994 · Nutrition Bulletin
- Characterizing the Relationship Between Energy Metabolism and Mesenchymal Stem Cell Therapy in the Infarcted HeartCurtis C. Hughey · 2013 · Libraries and Cultural Resources (University of Calgary)
- Assoziationen des A G Polymorphismus im Gen des Uncoupling Protein 1 mit Adipositas in der deutschen BevölkerungGesa Hagemann · 2001
- Origin of White and Brown Adipose Cells From Vascular Endothelium: A DissertationKhanh‐Van Tran · 2012 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
- UNDERSTANDING THE ROLE OF LIPOCALIN 2 AS AN IMPORTANT REGULATOR OF ENERGY METABOLISMYuanyuan Zhang · 2013 · University of Minnesota Digital Conservancy (University of Minnesota)
- A Função Endócrino-Metabólica do Tecido Adiposo Castanho e a sua aplicabilidade na prevenção e tratamento da obesidadeJoão Pedro Lopes Teixeira · 2010 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
- A Review of Preclinical Drug Development Models Utilised in Antiobesity ResearchGautam Arora, Sumeet Gullaiya, Shyam Sunder Aggrawal · 2014
- The roles of microRNAs in human mesenchymal stem cell adipogenesisE Kaiser Annette · 2012 · Arrow@dit (Dublin Institute of Technology)
- Optical Spectroscopic Properties of Brown Fat Reveal Pathophysiological ConditionsLianyu Guo, Wanzhu Jin, Le Qiu, Vladimir M. Turzhitsky, Edward I. Vitkin, Eugene B. Hanlon, Irving Itzkan, Lev T. Perelman · 2012 · Biomedical Optics and 3-D Imaging
- Treatment with CL316, 243 Improves Insulin Resistance by Down Regulation of Tumour Necrosis Factor-a (TNF-a) ExpressionGhorbani Masoud, Peyman Ghorbani, Mehdi Shafiee Ardestani · 2012 · Insight biomedical science
- The Alterations of Energy Metabolism-related Protein Patterns in Brown Adipose Tissue of Rats During Cold-induced ThermogenesisYue YANG, Wei GONG, Weiwei Wang, Xiaomin Yu, Songnian Hu, Jun Yu · 2010 · PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
- Molecular mechanisms of insulin-induced rat brown adipose tissue structural remodellingMilica B. Markelic · 2012
- Fat cells directly sense temperature to activateJun Wu, Paul Cohen, Lawrence Kazak, Melin Janardan Khandekar, Mark P. Jedrychowski, Xing Zeng, Steven P. Gygi, Bruce M. Spiegelman · 2013
- Adipose Drug Targets for Obesity TreatmentJean‐Paul Giacobino, Lorenz Lehr, Olivier Boss · 2007 · CRC Press eBooks
- Physiology, pathophysiology, and agingAlexander L. Berlin · 2011 · CRC Press eBooks