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A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis
Abstract
The KNOTTED class of plant genes encodes homeodomain proteins. These genes have been found in all plant species where they have been sought and, where examined, show expression patterns that suggest they play an important role in shoot meristem function. Until now, all mutant phenotypes associated with these genes have been due to gain-of-function mutations, making it difficult to deduce their wild-type function. Here we present evidence that the Arabidopsis SHOOT-MERISTEMLESS (STM) gene, required for shoot apical meristem formation during embryogenesis, encodes a class I KNOTTED-like protein. We also describe the expression pattern of this gene in the wild-type plant. To our knowledge, STM is the first gene shown to mark a specific pattern element in the developing plant embryo both phenotypically and molecularly.
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In the citing paper
“STM function is required for initiation and maintenance of the SAM (Long et al. 1996).”
From Molecular analysis of the LATERAL SUPPRESSOR gene in Arabidopsis reveals a conserved control mechanism for axillary meristem formation (2003) · cites this paper as Long et al. 1996
In the citing paper
“The homeodomain-containing protein SHOOT MERISTEMLESS (STM) was found to be expressed in all types of shoot meristems.”
From Molecular analysis of the LATERAL SUPPRESSOR gene in Arabidopsis reveals a conserved control mechanism for axillary meristem formation (2003) · cites this paper as Long et al. 1996
In the citing paper
“Meristematic identity of the SAM cells is retained by activity of the homeobox class I KNOX gene SHOOT MERISTEMLESS (STM; Long et al., 1996; Long and Barton, 2000).”
From Shaping plant architecture (2015) · cites this paper as Long et al., 1996
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Metadata
- Authors
- Long, J. A., Moan, E. I., Medford, J. I., & Barton, M. K.
- Affiliations
- University of Wisconsin–Madison (US)
- Pennsylvania State University (US)
- Venue
- Nature
- Published
- 1996-01
- Volume
- 379
- Issue
- 6560
- Pages
- 66-69
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1980630177
- Cited by
- 1,537
- References
- 20
- Citations by year
- 2026: 19 · 2025: 36 · 2024: 46 · 2023: 41 · 2022: 71 · 2021: 37 · 2020: 45 · 2019: 36 · 2018: 35 · 2017: 48 · 2016: 45 · 2015: 43 · 2014: 49 · 2013: 54 · 2012: 63
- FWCI
- 78.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Keywords
- STM, Arabidopsis thaliana, shoot apical meristem, embryonic development, gene expression patterns, gain-of-function mutations, plant development
- MeSH terms
- Amino Acid Sequence, Molecular Sequence Data, Plant Proteins, Gene Expression, Genes, Plant, Arabidopsis, Sequence Homology, Amino Acid, Homeodomain Proteins, Plant Shoots, RNA, Plant, Arabidopsis Proteins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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