Cited by 1,537Plant Molecular Biology ResearchDevelopmental Biology and Gene RegulationPlant Parasitism and Resistance

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis

Long, Jeff A., Moan, Erich I., Medford, June I., Barton, M. Kathryn·1996·Nature

Open this paper in CoChat — free account

Abstract

The KNOTTED class of plant genes encodes homeodomain proteins. These genes have been found in all plant species where they have been sought and, where examined, show expression patterns that suggest they play an important role in shoot meristem function. Until now, all mutant phenotypes associated with these genes have been due to gain-of-function mutations, making it difficult to deduce their wild-type function. Here we present evidence that the Arabidopsis SHOOT-MERISTEMLESS (STM) gene, required for shoot apical meristem formation during embryogenesis, encodes a class I KNOTTED-like protein. We also describe the expression pattern of this gene in the wild-type plant. To our knowledge, STM is the first gene shown to mark a specific pattern element in the developing plant embryo both phenotypically and molecularly.

Integrity signals

Registry

Crossref · 10.1038/379066a0

Cites

20 of 20 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The developmental gene Knotted-1 is a member of a maize homeobox gene family
Vollbrecht, E., Veit, B. E., Sinha, N. R., & Hake, S. (1991) · Nature · doi:10.1038/350241a0 · Cited by 760
Expression of maize KNOTTED1 related homeobox genes in the shoot apical meristem predicts patterns of morphogenesis in the vegetative shoot
Jackson, D., Veit, B. E., & Hake, S. (1994) · Development · doi:10.1242/dev.120.2.405 · Cited by 754
A knotted1-Like Homeobox Gene in Arabidopsis Is Expressed in the Vegetative Meristem and Dramatically Alters Leaf Morphology When Overexpressed in Transgenic Plants
Lincoln, C., Long, J. C., Yamaguchi, J., Serikawa, K. A., & Hake, S. (1994) · The Plant Cell · doi:10.1105/tpc.6.12.1859 · Cited by 684
Self-citation
Formation of the shoot apical meristem in Arabidopsis thaliana: an analysis of development in the wild type and in the shoot meristemless mutant
Barton, M. K., & Poethig, R. S. (1993) · Development · doi:10.1242/dev.119.3.823 · Cited by 626
Self-citation
Overexpression of the maize homeo box gene, KNOTTED-1, causes a switch from determinate to indeterminate cell fates.Preprint
Sinha, N. R., Williams, R., & Hake, S. (1993) · Genes & Development · doi:10.1101/gad.7.5.787 · Cited by 457
A dominant mutation in the maize homeobox gene, Knotted-1, causes its ectopic expression in leaf cells with altered fates
Smith, L. G., Greene, B. A., Veit, B. E., & Hake, S. (1992) · Development · doi:10.1242/dev.116.1.21 · Cited by 441
Sequence analysis and expression patterns divide the maize knotted1-like homeobox genes into two classes.
Kerstetter, R. A., Vollbrecht, E., Lowe, B., Veit, B. E., Yamaguchi, J., & Hake, S. (1994) · The Plant Cell · doi:10.1105/tpc.6.12.1877 · Cited by 332
The barley Hooded mutation caused by a duplication in a homeobox gene intron
Müller, K. J., Romano, N., Gerstner, O., García‐Maroto, F., Pozzi, C. M., Salamini, F., & Rohde, W. (1995) · Nature · doi:10.1038/374727a0 · Cited by 217
Early embryogenesis in Arabidopsis thaliana. I. The mature embryo sac
Mansfield, S. G., BRIARTY, L. G., & Erni, S. (1991) · Canadian Journal of Botany · doi:10.1139/b91-062 · Cited by 171
Effect of mutations in the PINHEAD gene of Arabidopsis on the formation of shoot apical meristems
McConnell, J. R., & Barton, M. K. (1995) · Developmental Genetics · doi:10.1002/dvg.1020160409 · Cited by 129
Self-citation

Flagged first, then by citations

Show all 20 references

Research works printed but not linked: 1

Arabidopsis: An Atlas or Morphology and Development (ed. Bowman, J.) 133–172 (Springer, New York, 1994).

Sorted by citations

The Stem Cell Population of Arabidopsis Shoot Meristems Is Maintained by a Regulatory Loop between the CLAVATA and WUSCHEL Genes
Schoof, H., Lenhard, M., Haecker, A., Mayer, K., Jürgens, G., & Laux, T. (2000) · Cell · doi:10.1016/s0092-8674(00)80700-x · Cited by 1,740
Role of WUSCHEL in Regulating Stem Cell Fate in the Arabidopsis Shoot Meristem
Mayer, K., Schoof, H., Haecker, A., Lenhard, M., Jürgens, G., & Laux, T. (1998) · Cell · doi:10.1016/s0092-8674(00)81703-1 · Cited by 1,689
IRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
NAC transcription factors: structurally distinct, functionally diverse
Olsen, A. N., Ernst, H. A., Leggio, L. L., & Skriver, K. (2005) · Trends in Plant Science · doi:10.1016/j.tplants.2004.12.010 · Cited by 1,498
Genes involved in organ separation in Arabidopsis: an analysis of the cup-shaped cotyledon mutant.
Aida, M., Ishida, T., Fukaki, H., Fujisawa, H., & Tasaka, M. (1997) · The Plant Cell · doi:10.1105/tpc.9.6.841 · Cited by 1,486
Patterns of Auxin Transport and Gene Expression during Primordium Development Revealed by Live Imaging of the Arabidopsis Inflorescence Meristem
Heisler, M. G., Ohno, C., Das, P., Sieber, P., Reddy, G. V., Long, J. A., & Meyerowitz, E. M. (2005) · Current Biology · doi:10.1016/j.cub.2005.09.052 · Cited by 1,189
Self-citation
Auxin Transport Promotes Arabidopsis Lateral Root Initiation
Casimiro, I., Marchant, A., Bhalerao, R. P., Beeckman, T., Dhooge, S., Swarup, R., Graham, N. S., Inzé, D., Sandberg, G., Casero, P. J., et al. (2001) · The Plant Cell · doi:10.1105/tpc.13.4.843 · Cited by 1,066
Arabidopsis LEAFY COTYLEDON1 Is Sufficient to Induce Embryo Development in Vegetative Cells
Lotan, T., Ohto, M., Yee, K. M., West, M. A. L., Lo, R. S., Kwong, R. W., Yamagishi, K., Fischer, R. L., Goldberg, R. B., & Harada, J. J. (1998) · Cell · doi:10.1016/s0092-8674(00)81463-4 · Cited by 1,063
The No Apical Meristem Gene of Petunia Is Required for Pattern Formation in Embryos and Flowers and Is Expressed at Meristem and Primordia Boundaries
Souer, E., van Houwelingen, A., Kloos, D., Mol, J., & Koes, R. (1996) · Cell · doi:10.1016/s0092-8674(00)81093-4 · Cited by 1,059
Genome-wide association study of leaf architecture in the maize nested association mapping population
Tian, F., Bradbury, P. J., Brown, P. J., Hung, H., Sun, Q., Flint-Garcia, S. A., Rocheford, T., McMullen, M. D., Holland, J. B., & Buckler, E. S. (2011) · Nature Genetics · doi:10.1038/ng.746 · Cited by 1,060
Auxin Regulates the Initiation and Radial Position of Plant Lateral Organs
Reinhardt, D., Mandel, T., & Kuhlemeier, C. J. (2000) · The Plant Cell · doi:10.1105/tpc.12.4.507 · Cited by 1,012
Direct control of shoot meristem activity by a cytokinin-activating enzyme
Kurakawa, T., Ueda, N., Maekawa, M., Kobayashi, K., Kojima, M., Nagato, Y., Sakakibara, H., & Kyozuka, J. (2007) · Nature · doi:10.1038/nature05504 · Cited by 989
WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators
Leibfried, A., To, J. P. C., Busch, W., Stehling-Sun, S., Kehle, A., Demar, M., Kieber, J. J., & Lohmann, J. U. (2005) · Nature · doi:10.1038/nature04270 · Cited by 854
Asymmetric leaves1 mediates leaf patterning and stem cell function in Arabidopsis
Byrne, M. E., Barley, R., Curtis, M. D., Arroyo, J. M., Dunham, M. J., Hudson, A., & Martienssen, R. A. (2000) · Nature · doi:10.1038/35050091 · Cited by 812
The Essential Basic Helix-Loop-Helix Protein FIT1 Is Required for the Iron Deficiency Response
Colangelo, E. P., & Guerinot, M. L. (2004) · The Plant Cell · doi:10.1105/tpc.104.024315 · Cited by 791
LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development
Stone, S. L., Kwong, L. W., Yee, K. M., Pelletier, J., Lepiniec, L., Fischer, R. L., Goldberg, R. B., & Harada, J. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.201413498 · Cited by 784
KNOX Action in Arabidopsis Is Mediated by Coordinate Regulation of Cytokinin and Gibberellin Activities
Jasinski, S., Piazza, P., Craft, J., Hay, A., Woolley, L., Rieu, I., Phillips, A., Hedden, P., & Tsiantis, M. (2005) · Current Biology · doi:10.1016/j.cub.2005.07.023 · Cited by 749
Members of the YABBY gene family specify abaxial cell fate in Arabidopsis
Siegfried, K. R., Eshed, Y., Baum, S. F., Otsuga, D., Drews, G. N., & Bowman, J. L. (1999) · Development · doi:10.1242/dev.126.18.4117 · Cited by 744
Short-range control of cell differentiation in the Arabidopsis root meristem
van den Berg, C., Willemsen, V., Hendriks, G., Weisbeek, P. J., & Scheres, B. (1997) · Nature · doi:10.1038/36856 · Cited by 724
MicroRNA Regulation of NAC-Domain Targets Is Required for Proper Formation and Separation of Adjacent Embryonic, Vegetative, and Floral Organs
Mallory, A. C., Dugas, D. V., Bartel, D. P., & Bartel, B. (2004) · Current Biology · doi:10.1016/j.cub.2004.06.022 · Cited by 697
Cytokinin Regulates the Activity of Reproductive Meristems, Flower Organ Size, Ovule Formation, and Thus Seed Yield in Arabidopsis thaliana
Bartrina, I., Otto, E., Strnad, M., Werner, T., & Schmülling, T. (2011) · The Plant Cell · doi:10.1105/tpc.110.079079 · Cited by 693
CONSTANS acts in the phloem to regulate a systemic signal that induces photoperiodic flowering of Arabidopsis
An, H., Roussot, C., Suárez‐López, P., Corbesier, L., Vincent, C. A., Piñeiro, M., Hepworth, S. R., Mouradov, A., Justin, S., Turnbull, C. G. N., et al. (2004) · Development · doi:10.1242/dev.01231 · Cited by 690
Auxin–Cytokinin Interaction Regulates Meristem Development
Su, Y.-H., Liu, Y.-B., & Zhang, X. (2011) · Molecular Plant · doi:10.1093/mp/ssr007 · Cited by 708
Molecular Basis of Plant Architecture
Wang, Y., & Li, J. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092902 · Cited by 655
Establishment of polarity in lateral organs of plants
Eshed, Y., Baum, S. F., Perea, J. V., & Bowman, J. L. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00392-x · Cited by 635
Real‐time RT‐PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root‐ and shoot‐specific genes
Czechowski, T., Bari, R. P., Stitt, M., Scheible, W., & Udvardi, M. K. (2004) · The Plant Journal · doi:10.1111/j.1365-313x.2004.02051.x · Cited by 621
A leucine-rich repeat containing receptor-like kinase marks somatic plant cells competent to form embryos
Schmidt, E. D. L., Guzzo, F., Toonen, M. A. J., & de Vries, S. C. (1997) · Development · doi:10.1242/dev.124.10.2049 · Cited by 609
KNOX genes: versatile regulators of plant development and diversity
Hay, A., & Tsiantis, M. (2010) · Development · doi:10.1242/dev.030049 · Cited by 602
Leaf polarity and meristem formation in Arabidopsis
McConnell, J. R., & Barton, M. K. (1998) · Development · doi:10.1242/dev.125.15.2935 · Cited by 592
Self-citation
The CUP-SHAPED COTYLEDON1 gene of Arabidopsis regulates shoot apical meristem formation
Takada, S., Hibara, K.-I., Ishida, T., & Tasaka, M. (2001) · Development · doi:10.1242/dev.128.7.1127 · Cited by 587
Shoot apical meristem and cotyledon formation during Arabidopsis embryogenesis: interaction among the CUP-SHAPED COTYLEDON and SHOOT MERISTEMLESS genes
Aida, M., Ishida, T., & Tasaka, M. (1999) · Development · doi:10.1242/dev.126.8.1563 · Cited by 557
The Lateral Organ Boundaries Gene Defines a Novel, Plant-Specific Gene Family
Shuai, B., Reynaga-Peña, C. G., & Springer, P. S. (2002) · Plant Physiology · doi:10.1104/pp.010926 · Cited by 555
A genetic framework for floral patterning
Parcy, F., Nilsson, O. R., Busch, M. A., Lee, I., & Weigel, D. (1998) · Nature · doi:10.1038/26903 · Cited by 551
Arabidopsis KNOXI Proteins Activate Cytokinin Biosynthesis
Yanai, O., Shani, E., Doležal, K., Tarkowski, P., Sablowski, R. W. M., Sandberg, G., Samach, A., & Ori, N. (2005) · Current Biology · doi:10.1016/j.cub.2005.07.060 · Cited by 567
Molecular analysis of the LATERAL SUPPRESSOR gene in Arabidopsis reveals a conserved control mechanism for axillary meristem formation
Greb, T., Clarenz, O., Schäfer, E., Müller, D., Herrero, R., Schmitz, G., & Theres, K. (2003) · Genes & Development · doi:10.1101/gad.260703 · Cited by 541
“STM function is required for initiation and maintenance of the SAM (Long et al. 1996).”
Background
Survival of the flexible: hormonal growth control and adaptation in plant development
Wolters, H., & Jürgens, G. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2558 · Cited by 553
In Posidonia oceanica cadmium induces changes in DNA methylation and chromatin patterning
Greco, M., Chiappetta, A. A. C., Bruno, L., & Bitonti, M. B. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/err313 · Cited by 555
Multiple feedback loops through cytokinin signaling control stem cell number within the Arabidopsis shoot meristem
Gordon, S., Chickarmane, V. S., Ohno, C. K., & Meyerowitz, E. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908122106 · Cited by 523
Dissection of floral induction pathways using global expression analysis
Schmid, M., Uhlenhaut, N. H., Godard, F., Demar, M., Bressan, R. A., Weigel, D., & Lohmann, J. U. (2003) · Development · doi:10.1242/dev.00842 · Cited by 493
The PHANTASTICA Gene Encodes a MYB Transcription Factor Involved in Growth and Dorsoventrality of Lateral Organs in Antirrhinum
Waites, R., Selvadurai, H. R. N., Oliver, I. R., & Hudson, A. (1998) · Cell · doi:10.1016/s0092-8674(00)81439-7 · Cited by 487
The CUP-SHAPED COTYLEDON3 Gene Is Required for Boundary and Shoot Meristem Formation in Arabidopsis
Vroemen, C. W., Mordhorst, A. P., Albrecht, C., Kwaaitaal, M. A. C. J., & de Vries, S. C. (2003) · The Plant Cell · doi:10.1105/tpc.012203 · Cited by 480
KNAT1 induces lobed leaves with ectopic meristems when overexpressed in Arabidopsis.
Chuck, G., Lincoln, C., & Hake, S. (1996) · The Plant Cell · doi:10.1105/tpc.8.8.1277 · Cited by 478
REVOLUTA regulates meristem initiation at lateral positions
Otsuga, D., DeGuzman, B., Prigge, M. J., Drews, G. N., & Clark, S. E. (2001) · The Plant Journal · doi:10.1046/j.1365-313x.2001.00959.x · Cited by 473
The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana regulates formation of a symmetric lamina, establishment of venation and repression of meristem-related homeobox genes in leaves
Semiarti, E., Ueno, Y., Tsukaya, H., Iwakawa, H., Machida, C., & Machida, Y. (2001) · Development · doi:10.1242/dev.128.10.1771 · Cited by 467
The PINHEAD/ZWILLE gene acts pleiotropically in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene
Lynn, K., Fernandez, A. G., Aida, M., Sedbrook, J. C., Tasaka, M., Masson, P., & Barton, M. K. (1999) · Development · doi:10.1242/dev.126.3.469 · Cited by 465
Self-citation
THE ROLE OF KNOX GENES IN PLANT DEVELOPMENT
Hake, S., Smith, H. M. S., Holtan, H., Magnani, E., Mele, G., & Ramirez, J. C. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.031803.093824 · Cited by 456
Growth-Regulating Factors (GRFs): A Small Transcription Factor Family with Important Functions in Plant Biology
Omidbakhshfard, M. A., Proost, S., Fujikura, U., & Mueller‐Roeber, B. (2015) · Molecular Plant · doi:10.1016/j.molp.2015.01.013 · Cited by 459
The Gibberellin Pathway Mediates KNOTTED1-Type Homeobox Function in Plants with Different Body Plans
Hay, A., Kaur, H., Phillips, A. L., Hedden, P., Hake, S., & Tsiantis, M. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01125-9 · Cited by 451
Overexpression of the FRO2 Ferric Chelate Reductase Confers Tolerance to Growth on Low Iron and Uncovers Posttranscriptional Control
Connolly, E. L., Campbell, N. H., Grotz, N., Prichard, C. L., & Guerinot, M. L. (2003) · PLANT PHYSIOLOGY · doi:10.1104/pp.103.025122 · Cited by 451
Mechanisms that control knox gene expression in the Arabidopsis shoot
Ori, N., Eshed, Y., Chuck, G. S., Bowman, J. L., & Hake, S. (2000) · Development · doi:10.1242/dev.127.24.5523 · Cited by 449
N6-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis
Shen, L., Liang, Z., Gu, X., Chen, Y., Teo, Z. W. N., Hou, X., Cai, W. M., Dedon, P. C., Liu, L., & Yu, H. Q. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.06.008 · Cited by 442
KNOX homeodomain protein directly suppresses the expression of a gibberellin biosynthetic gene in the tobacco shoot apical meristemPreprint
Sakamoto, T., Kamiya, N., Ueguchi‐Tanaka, M., Iwahori, S., & Matsuoka, M. (2001) · Genes & Development · doi:10.1101/gad.867901 · Cited by 440
Synergistic interaction of three ERECTA-family receptor-like kinases controls Arabidopsis organ growth and flower development by promoting cell proliferation
Shpak, E. D., Berthiaume, C. T., Hill, E. J., & Torii, K. U. (2004) · Development · doi:10.1242/dev.01028 · Cited by 424
Pluripotency of Arabidopsis xylem pericycle underlies shoot regeneration from root and hypocotyl explants grown in vitro
Atta, R., Laurens, L. M. L., Boucheron‐Dubuisson, E., Guivarc’h, A., Carnero-Díaz, E., Pautot, V., Rech, P., & Chriqui, D. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03715.x · Cited by 423
Molecular analysis of SCARECROW function reveals a radial patterning mechanism common to root and shoot
Wysocka‐Diller, J. W., Helariutta, Y., Fukaki, H., Malamy, J. E., & Benfey, P. N. (2000) · Development · doi:10.1242/dev.127.3.595 · Cited by 412
The genetic basis for differences in leaf form between Arabidopsis thaliana and its wild relative Cardamine hirsuta
Hay, A., & Tsiantis, M. (2006) · Nature Genetics · doi:10.1038/ng1835 · Cited by 406
ASYMMETRIC LEAVES1revealsknoxgene redundancy inArabidopsis
Byrne, M. E., Simorowski, J., & Martienssen, R. A. (2002) · Development · doi:10.1242/dev.129.8.1957 · Cited by 405
LEAFY COTYLEDON1-LIKE Defines a Class of Regulators Essential for Embryo Development
Kwong, R. W., Bui, A. Q., Lee, H., Kwong, L. W., Fischer, R. L., Goldberg, R. B., & Harada, J. J. (2002) · The Plant Cell · doi:10.1105/tpc.006973 · Cited by 403
The CLAVATA and SHOOT MERISTEMLESS loci competitively regulate meristem activity in Arabidopsis
Clark, S. E., Jacobsen, S. E., Levin, J. Z., & Meyerowitz, E. M. (1996) · Development · doi:10.1242/dev.122.5.1567 · Cited by 402
Regulation of shoot epidermal cell differentiation by a pair of homeodomain proteins in Arabidopsis
Abe, M., Katsumata, H., Komeda, Y., & Takahashi, T. (2003) · Development · doi:10.1242/dev.00292 · Cited by 396
Pattern formation during de novo assembly of the Arabidopsis shoot meristem
Gordon, S., Heisler, M. G., Reddy, G. V., Ohno, C. K., Das, P. K., & Meyerowitz, E. M. (2007) · Development · doi:10.1242/dev.010298 · Cited by 388
Arabidopsis CUP-SHAPED COTYLEDON3 Regulates Postembryonic Shoot Meristem and Organ Boundary Formation
Hibara, K.-I., Karim, M. R., Takada, S., Taoka, K.-I., Furutani, M., Aida, M., & Tasaka, M. (2006) · The Plant Cell · doi:10.1105/tpc.106.045716 · Cited by 387
Proteolysis in plants: mechanisms and functions
Vierstra, R. D. (1996) · Plant Molecular Biology · doi:10.1007/bf00039386 · Cited by 386
Specification of Leaf Polarity in Arabidopsis via the trans-Acting siRNA Pathway
Garcia, D., Collier, S. A., Byrne, M. E., & Martienssen, R. A. (2006) · Current Biology · doi:10.1016/j.cub.2006.03.064 · Cited by 378
Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis
Moussian, B., Schoof, H., Haecker, A., Jürgens, G., & Laux, T. (1998) · The EMBO Journal · doi:10.1093/emboj/17.6.1799 · Cited by 376
Distinct Mechanisms Promote Polarity Establishment in Carpels of Arabidopsis
Eshed, Y., Baum, S. F., & Bowman, J. L. (1999) · Cell · doi:10.1016/s0092-8674(00)81651-7 · Cited by 374
The development of apical embryonic pattern in Arabidopsis
Long, J. A., & Barton, M. K. (1998) · Development · doi:10.1242/dev.125.16.3027 · Cited by 372
Self-citation
Twenty years on: The inner workings of the shoot apical meristem, a developmental dynamo
Barton, M. K. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.11.029 · Cited by 372
Self-citation
Genetic Control of Cell Division Patterns in Developing Plants
Meyerowitz, E. M. (1997) · Cell · doi:10.1016/s0092-8674(00)81868-1 · Cited by 368
Phloem long-distance transport ofCmNACPmRNA: implications for supracellular regulation in plants
Ruíz‐Medrano, R., Xoconostle‐Cázares, B., & Lucas, W. J. (1999) · Development · doi:10.1242/dev.126.20.4405 · Cited by 367
Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems
Jacobsen, S. E., Running, M., & Meyerowitz, E. M. (1999) · Development · doi:10.1242/dev.126.23.5231 · Cited by 367
Identification of a Meristem L1 Layer-Specific Gene in Arabidopsis That Is Expressed during Embryonic Pattern Formation and Defines a New Class of Homeobox Genes
Lü, P., Porat, R., Nadeau, J. A., & O’Neill, S. D. (1996) · The Plant Cell · doi:10.1105/tpc.8.12.2155 · Cited by 365
Vacuolar cation/H + exchange, ion homeostasis, and leaf development are altered in a T‐DNA insertional mutant of AtNHX1 , the Arabidopsis vacuolar Na + /H + antiporter
Apse, M. P., Sottosanto, J. B., & Blumwald, E. (2003) · The Plant Journal · doi:10.1046/j.1365-313x.2003.01871.x · Cited by 364
Initiation of Axillary and Floral Meristems in Arabidopsis
Long, J., & Barton, M. K. (2000) · Developmental Biology · doi:10.1006/dbio.1999.9572 · Cited by 357
Self-citation
A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration
Zhang, T., Lian, H., Zhou, C., Xu, L., Jiao, Y., & Wang, J. (2017) · The Plant Cell · doi:10.1105/tpc.16.00863 · Cited by 361
CLAVATA2, a regulator of meristem and organ development in Arabidopsis
Kayes, J. M., & Clark, S. E. (1998) · Development · doi:10.1242/dev.125.19.3843 · Cited by 356
SHOOT BRANCHING
McSteen, P., & Leyser, O. (2005) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.56.032604.144122 · Cited by 356
Stem-cell niches: nursery rhymes across kingdoms
Scheres, B. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2164 · Cited by 365
Plant Stem Cell Niches
Aichinger, E., Kornet, N., Friedrich, T., & Laux, T. (2012) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105555 · Cited by 350
The WUSCHEL and SHOOTMERISTEMLESS genes fulfil complementary roles in Arabidopsis shoot meristem regulation
Lenhard, M., Jürgens, G., & Laux, T. (2002) · Development · doi:10.1242/dev.129.13.3195 · Cited by 341
Molecular analysis of NOZZLE , a gene involved in pattern formation and early sporogenesis during sex organ development in Arabidopsis thaliana
Schiefthaler, U., Balasubramanian, S., Sieber, P., Chevalier, D., Wisman, E., & Schneitz, K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11664 · Cited by 340
Real-time lineage analysis reveals oriented cell divisions associated with morphogenesis at the shoot apex of Arabidopsis thaliana
Reddy, G. V., Heisler, M. G., Ehrhardt, D. W., & Meyerowitz, E. M. (2004) · Development · doi:10.1242/dev.01261 · Cited by 339
A developmental framework for dissected leaf formation in the Arabidopsis relative Cardamine hirsuta
Barkoulas, M., Hay, A., Kougioumoutzi, E., & Tsiantis, M. (2008) · Nature Genetics · doi:10.1038/ng.189 · Cited by 329
The fasciated ear2 gene encodes a leucine-rich repeat receptor-like protein that regulates shoot meristem proliferation in maizePreprint
Taguchi‐Shiobara, F., Yuan, Z., Hake, S., & Jackson, D. P. (2001) · Genes & Development · doi:10.1101/gad.208501 · Cited by 326
Direct Repression of KNOX Loci by the ASYMMETRIC LEAVES1 Complex of Arabidopsis
Guo, M., Thomas, J., Collins, G. A., & Timmermans, M. C. P. (2008) · The Plant Cell · doi:10.1105/tpc.107.056127 · Cited by 324
Leaf Shape Evolution Through Duplication, Regulatory Diversification, and Loss of a Homeobox Gene
Vlad, D., Kierzkowski, D., Rast, M. I., Vuolo, F., Dello Ioio, R., Galinha, C., Gan, X., Hajheidari, M., Hay, A., Smith, R. S., et al. (2014) · Science · doi:10.1126/science.1248384 · Cited by 323
Overexpression of Arabidopsis ESR1 Induces Initiation of Shoot Regeneration
Banno, H., Ikeda, Y., Niu, Q., & Chua, N. (2001) · The Plant Cell · doi:10.1105/tpc.010234 · Cited by 321
A Link Between mRNA Turnover and RNA Interference in Arabidopsis
Gazzani, S., Lawrenson, T., Woodward, C., Headon, D., & Sablowski, R. W. M. (2004) · Science · doi:10.1126/science.1101092 · Cited by 318
thick tassel dwarf1encodes a putative maize ortholog of theArabidopsis CLAVATA1leucine-rich repeat receptor-like kinase
Bommert, P., Lunde, C. F., Nardmann, J., Vollbrecht, E., Running, M., Jackson, D. P., Hake, S., & Werr, W. (2005) · Development · doi:10.1242/dev.01671 · Cited by 317
Loss-of-function mutations in the maize homeobox gene, knotted1, are defective in shoot meristem maintenance
Kerstetter, R. A., Laudencia‐Chingcuanco, D., Smith, L. G., & Hake, S. (1997) · Development · doi:10.1242/dev.124.16.3045 · Cited by 313
Flower Development
Alvarez-Buylla, E. R., Benítez, M., Corvera-Poiré, A., Chaos, Á., de Folter, S., Buen, A. G.-D., Garay‐Arroyo, A., García‐Ponce, B., Jaimes‐Miranda, F., Pérez-Ruíz, R. V., et al. (2010) · The Arabidopsis Book · doi:10.1199/tab.0127 · Cited by 330
The Maize Transcription Factor KNOTTED1 Directly Regulates the Gibberellin Catabolism Gene ga2ox1
Bolduc, N., & Hake, S. (2009) · The Plant Cell · doi:10.1105/tpc.109.068221 · Cited by 312
The role of JAGGED in shaping lateral organs
Dinneny, J. R., Yadegari, R., Fischer, R. L., Yanofsky, M. F., & Weigel, D. (2004) · Development · doi:10.1242/dev.00949 · Cited by 311
ASYMMETRIC LEAVES1 and auxin activities converge to repressBREVIPEDICELLUSexpression and promote leaf development inArabidopsis
Hay, A., Barkoulas, M., & Tsiantis, M. (2006) · Development · doi:10.1242/dev.02545 · Cited by 316
GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana
Sawa, M., & Kay, S. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1106771108 · Cited by 306
Shoot meristem maintenance is controlled by a GRAS -gene mediated signal from differentiating cellsPreprint
Stuurman, J., Jäggi, F., & Kuhlemeier, C. J. (2002) · Genes & Development · doi:10.1101/gad.230702 · Cited by 306
Differentiating Arabidopsis Shoots from Leaves by Combined YABBY Activities
Sarojam, R., Sappl, P. G., Goldshmidt, A., Efroni, I., Floyd, S. K., Eshed, Y., & Bowman, J. L. (2010) · The Plant Cell · doi:10.1105/tpc.110.075853 · Cited by 311
AGAMOUS Terminates Floral Stem Cell Maintenance in Arabidopsis by Directly Repressing WUSCHEL through Recruitment of Polycomb Group Proteins
Liu, X., Kim, Y. J., Müller-Xing, R., Yumul, R. E., Liu, C., Pan, Y., Cao, X., Goodrich, J., & Chen, X. (2011) · The Plant Cell · doi:10.1105/tpc.111.091538 · Cited by 304
MicroRNAs in Control of Plant Development
Li, C., & Zhang, B. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.25125 · Cited by 306
The diverse roles of cytokinins in regulating leaf development
Wu, W., Du, K., Kang, X., & Wei, H. (2021) · Horticulture Research · doi:10.1038/s41438-021-00558-3 · Cited by 302

Authors: Long, J. A., Moan, E. I., Medford, J. I., & Barton, M. K.
Affiliations: University of Wisconsin–Madison (US)
Pennsylvania State University (US)
ORCID: Long, Jeff A.
Medford, June I.
Barton, M. Kathryn
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1996-01
Volume: 379
Issue: 6560
Pages: 66-69
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/379066a0
OpenAlex: W1980630177
Cited by: 1,537
References: 20
Citations by year: 2026: 19 · 2025: 36 · 2024: 46 · 2023: 41 · 2022: 71 · 2021: 37 · 2020: 45 · 2019: 36 · 2018: 35 · 2017: 48 · 2016: 45 · 2015: 43 · 2014: 49 · 2013: 54 · 2012: 63
FWCI: 78.23
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
Keywords: STM, Arabidopsis thaliana, shoot apical meristem, embryonic development, gene expression patterns, gain-of-function mutations, plant development
MeSH terms: Amino Acid Sequence, Molecular Sequence Data, Plant Proteins, Gene Expression, Genes, Plant, Arabidopsis, Sequence Homology, Amino Acid, Homeodomain Proteins, Plant Shoots, RNA, Plant, Arabidopsis Proteins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks