Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 247

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

Schreuder, Herman, Tardif, Chantal, Trump-Kallmeyer, Susanne, Soffientini, Adolfo, Sarubbi, Edoardo, Akeson, Ann, Bowlin, Terry, Yanofsky, Stephen, Barrett, Ronald W.·1997·Nature
DOI 10.1038/386194a0
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/386194a0

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 2 references

Research works printed but not linked: 28

  1. Baumann, H. & Gauldie, J. The acute phase response. Immunol. Today 15, 74–80 (1994). · DOI · Paper page
  2. Evans, R. J. et al. Mapping receptor binding sites in interleukin (IL)-l receptor antagonist and IL-1β by site-directed mutagenesis. Identificaiton of a single site in IL-lra and two sites in IL-1β. J. Biol. Chem. 270, 11477–11483 (1995). · DOI
  3. Schreuder, H. A. et al. Crystals of soluble interleukin-1 receptor complexed with its natural antagonist reveal a 1:1 receptor-ligand complex. FEBS Lett. 373, 39–40 (1995). · DOI
  4. Schreuder, H. A. et al. Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis proline. Eur. J. Biochem. 227, 838–847 (1995). · DOI
  5. Sims, J. E. et al. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241, 585–589 (1988). · DOI · Paper page
  6. Harpaz, Y. & Chothia, C. Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains. J. Mol. Biol. 238, 528–539 (1994). · DOI · Paper page
  7. Hemmingsen, J. M., Gernert, K. M., Richardson, J. S. & Richardson, D. C. The tyrosine corner: A feature of most greek key β-barrel proteins. Prot. Sci. 3, 1927–1937 (1994). · DOI
  8. Clackson, T. & Wells, J. A. A hot spot of binding energy in a hormone-receptor interface. Science 267, 383–386 (1995). · DOI · Paper page
  9. Yanofksy, S. D. et al. High affinity type I interleukin 1 receptor antagonists discovered by screening recombinant peptide libraries. Proc. Natl Acad. Sci. USA 93, 7381–7386 (1996). · DOI
  10. Banner, D. W. et al. Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation. Cell 73, 431–445 (1993). · DOI · Paper page
  11. Vos, A. M., Ultsch, M. & Kossiakoff, A. A. Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex. Science 255, 306–312 (1992). · DOI · Paper page
  12. Walter, M. R. et al. Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor. Nature 376, 230–235 (1995). · DOI · Paper page
  13. Livnah, O. et al. Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 Å. Science 273, 464–471 (1996). · DOI · Paper page
  14. Greenfeder, S. A. et al. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270, 13757–13765 (1995). · DOI · Paper page
  15. Priestle, J. P., Schär, H.-P. & Grütter, M. G. Crystal structure of the cytokine interleukin-1β. EMBOJ. 7, 339–343 (1988). · DOI
  16. Ju, G. et al. Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesis. Proc. Natl Acad. Sci. USA 88, 2658–2662 (1991). · DOI
  17. Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Crystallogr. 26, 795–800 (1993). · DOI · Paper page
  18. Navaza, J. AMoRe: an automated package for molecular replacement. Acta Crystallogr. A 50, 157–163 (1994). · DOI · Paper page
  19. Wang, J. et al. Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature 348, 411–418 (1990). · DOI · Paper page
  20. Collaborative Computational Project Number 4. The CCP4 suite: Programs for protein crystallography. Acta Crystallogr. D 50, 760–763 (1994). · DOI · Paper page
  21. Terwilliger, T. C . & Eisenberg, D. Unbiased three-dimensional refinement of heavy-atom parameters by correlation of origin-removed Patterson functions. Acta Crystallogr. A 39, 813–817 (1983). · DOI · Paper page
  22. Otwinowsky, W. Maximum likelihood refinement of heavy atom parameters. In Isomorphous Replacement and Anomalous Scattering Proc. CCP4 Study Weekend, 25-26 January 1991 (compiled by Wolf, W., Evans, P. R. & Lesly, A. G. W.) 80–86 (1991).
  23. Read, R.J. & Schierbeek, A. J. A phased translation function. J. Appl Crystallogr. 13, 490–495 (1988). · doi:10.1107/s002188988800562x
  24. Zhang, K. Y. J. SQUASH-combining constraints for macromolecular phase refinement and extension. Acta Crystallogr. D 49, 213–222 (1993). · DOI
  25. Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47, 110–119 (1991). · DOI · Paper page
  26. Brünger, A. X-PLOR, version 3.1. A system for X-ray crystallography and NMR. (Yale University Press, New Haven, Connecticut, 1992).
  27. Kraulis, P. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24, 946–950 (1991). · DOI · Paper page
  28. Nicholls, A., Sharp, K. A. & Honig, B. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11, 281–296 (1991). · DOI · Paper page

Cited by

See all 247

Metadata

Authors
Schreuder, H., Tardif, C., Trump-Kallmeyer, S., Soffientini, A., Sarubbi, E., Akeson, A., Bowlin, T., Yanofsky, S., & Barrett, R. W.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
1997-03
Volume
386
Issue
6621
Pages
194-200
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
DOI
10.1038/386194a0
OpenAlex
W2046950192
Cited by
247
References
2
FWCI
5.87
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist. https://app.cochat.ai/papers/10.1038/386194a0
The paper
Schreuder, H., Tardif, C., Trump-Kallmeyer, S., Soffientini, A., Sarubbi, E., Akeson, A., Bowlin, T., Yanofsky, S., & Barrett, R. W. (1997). A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist. Nature. https://doi.org/10.1038/386194a0

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.