The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily
Abstract
Interleukin-1 alpha and -1 beta (IL-1α and IL-1β) are cytokines that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis. A direct expression strategy was used to clone the receptor for IL-1 from mouse T cells. The product of the cloned complementary DNA binds both IL-1α and IL-1β in a manner indistinguishable from that of the native T cell IL-1 receptor. The extracellular, IL-1 binding portion of the receptor is 319 amino acids in length and is composed of three immunoglobulin-like domains. The cytoplasmic portion of the receptor is 217 amino acids long.
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Cites
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
Birnboim, H. C., & Doly, J. (1979) · Nucleic Acids Research · doi:10.1093/nar/7.6.1513 · Cited by 14,686
Cited by
The history of toll-like receptors - redefining innate immunity
O'Neill, L. A. J., Golenbock, D., & Bowie, A. G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3446 · Cited by 1,765
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Yasukawa, K., Matsuda, T., Hirano, T., & Kishimoto, T. (1989) · Cell · doi:10.1016/0092-8674(89)90438-8 · Cited by 1,396
Molecular cloning and expression of an IL-6 signal transducer, gp130
Hibi, M., Murakami, M., Saito, M., Hirano, T., Taga, T., & Kishimoto, T. (1990) · Cell · doi:10.1016/0092-8674(90)90411-7 · Cited by 1,039
Interleukin-1 and neuronal injury
Allan, S. M., Tyrrell, P. J., & Rothwell, N. J. (2005) · Nature Reviews Immunology · doi:10.1038/nri1664 · Cited by 992
Molecular cloning and expression of a receptor for human tumor necrosis factor
Schall, T. J., Lewis, M., Koller, K. J., Lee, A., Rice, G. C., Wong, G. H. W., Gatanaga, T., Granger, G. A., Lentz, R., Raab, H., et al. (1990) · Cell · doi:10.1016/0092-8674(90)90816-w · Cited by 964
Metadata
- Authors
- Sims, J. E., March, C. J., Cosman, D., Widmer, M. B., MacDonald, H. R., McMahan, C. J., Grubin, C. E., Wignall, J. M., Jackson, J. L., Call, S. M., Friend, D., Alpert, A. R., Gillis, S., Urdal, D. L., & Dower, S. K.
- Venue
- Science
- Published
- 1988-07-29
- Volume
- 241
- Issue
- 4865
- Pages
- 585-589
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1976887761
- Cited by
- 889
- References
- 1
- FWCI
- 42.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily. https://app.cochat.ai/papers/10.1126/science.2969618
- The paper
- Sims, J. E., March, C. J., Cosman, D., Widmer, M. B., MacDonald, H. R., McMahan, C. J., Grubin, C. E., Wignall, J. M., Jackson, J. L., Call, S. M., Friend, D., Alpert, A. R., Gillis, S., Urdal, D. L., & Dower, S. K. (1988). cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily. Science. https://doi.org/10.1126/science.2969618
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
