Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

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Items 601–700 of 1,000

1. Anti-HIV designer T cells progressively eradicate a latently infected cell line by sequentially inducing HIV reactivation then killing the newly gp120-positive cells
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2. Modeling the Effects of Vorinostat In Vivo Reveals both Transient and Delayed HIV Transcriptional Activation and Minimal Killing of Latently Infected Cells
   Ruian Ke, Sharon R. Lewin, Julian H. Elliott, Alan S. Perelson · 2015 · PLoS Pathogens
3. Thirty Years with HIV Infection—Nonprogression Is Still Puzzling: Lessons to Be Learned from Controllers and Long-Term Nonprogressors
   Julie Christine Gaardbo, Hans Jakob Hartling, Jan Gerstoft, Susanne Dam Nielsen · 2012 · AIDS Research and Treatment
4. Evidence that CD32a does not mark the HIV-1 latent reservoir
   Christa Elyse Osuna, So‐Yon Lim, Jessica L. Kublin, Richard Apps, Elsa Chen, Talia M. Mota, Szu-Han Huang, Yanqin Ren, Nathaniel D. Bachtel, Athe M. N. Tsibris et al. · 2018 · Nature
5. Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional Cure
   Luisa Mori, Susana T. Valente · 2020 · Viruses
6. Minimizing DNA recombination during long RT-PCR
   Guowei Fang, Guan Zhu, Harold Burger, Janet S. Keithly, Barbara Weiser · 1998 · Journal of Virological Methods
7. CSF-induced and HIV-1–mediated Distinct Regulation of Hck and C/EBPβ Represent a Heterogeneous Susceptibility of Monocyte-derived Macrophages to M-tropic HIV-1 Infection
   Iwao Komuro, Y Yokota, Sachiko Yasuda, Aikichi Iwamoto, Kiyoko S. Kagawa · 2003 · The Journal of Experimental Medicine
8. A Randomized Trial of Interferon alpha Therapy for HIV Type 1 Infection
   David W. Haas, James P. Lavelle, Jeffrey P. Nadler, Stephen B. Greenberg, Peter T. Frame, Norman Mustafa, Marty St. Clair, Ray A. McKinnis, Lynn P. Dix, Mary Elkins et al. · 2000 · AIDS Research and Human Retroviruses
9. Quantification of In Vivo Replicative Capacity of HIV-1 in Different Compartments of Infected Cells
   Georg A. Funk, Marek Fischer, Béda Joos, Milos Opravil, Huldrych F. Günthard, Bruno Ledergerber, Sebastian Bonhoeffer · 2001 · JAIDS Journal of Acquired Immune Deficiency Syndromes
10. Antigenic stimulation by BCG vaccine as an in vivo driving force for SIV replication and dissemination
    Rémi Cheynier, Sophie Gratton, Matilda Halloran, Ingrid Stahmer, Norman L. Letvin, Simon Wain–Hobson · 1998 · Nature Medicine
11. British HIV Association (BHIVA) guidelines for the treatment of HIV‐infected adults with antiretroviral therapy
    Study design may have an important influence on the rate of discontinuation in drug trials. An open trial design may result in higher levels of discontinuation from what is perceived to be the least effective regimen, while a double-blind, placebo-controlled study may reduce adherence in all groups because of the large pill burden. It is important to recognize, however, that controlled clinical trials provide an optimal treatment setting and results in the ‘real world’ are usually not as good. · 2000 · HIV Medicine
12. Acute HIV Syndrome after Discontinuation of Antiretroviral Therapy in a Patient Treated before Seroconversion
    Eric S. Daar, Jiexin Bai, Mary Ann Hausner, Martin Majchrowicz, Mojgan Tamaddon, Janis V. Giorgi · 1998 · Annals of Internal Medicine
13. HIV/Mtb Co-Infection: From the Amplification of Disease Pathogenesis to an “Emerging Syndemic”
    José Miguel Azevedo‐Pereira, David Pires, Marta S. Calado, Manoj Mandal, Quirina Santos‐Costa, Elsa Anes · 2023 · Microorganisms
14. Electron Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue
    Mark S. Ladinsky, Collin Kieffer, Gregory S. Olson, Maud Déruaz, Vladimir D. Vrbanac, Andrew Martin Tager, Douglas S. Kwon, Pamela J. Björkman · 2014 · PLoS Pathogens
15. HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites
    Nitin K. Saksena · 2010 · HIV/AIDS - Research and Palliative Care
16. Human Immunodeficiency Virus Integration Efficiency and Site Selection in Quiescent CD4 + T Cells
    Dimitrios N. Vatakis, Sanggu Kim, Namshin Kim, S A Chow, Jerome A. Zack · 2009 · Journal of Virology
17. Predictors of Residual Viremia in HIV‐Infected Patients Successfully Treated with Efavirenz and Lamivudine plus either Tenofovir or Stavudine
    Diane V. Havlir, Kersten K. Koelsch, Matthew C. Strain, Nicolas Margot, Biao Lu, Caroline C. Ignacio, Michael D. Miller, Joseph K. Wong, Gilead 903 Study Team · 2005 · The Journal of Infectious Diseases
18. Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women
    Mark D Pankau, Daniel B. Reeves, Elias Harkins, Keshet Ronen, Walter Godfrey Jaoko, Kishor N. Mandaliya, Susan Marie Graham, R. Scott McClelland, Frederick A. Matsen IV, Joshua Tisdell Schiffer et al. · 2020 · PLoS Pathogens
19. Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral therapy
    Angelos E. Hatzakis, Giota Touloumi, Nikos Pantazis, Cleo G. Anastassopoulou, Όλγα Κατσαρού, Anastasia Karafoulidou, James J. Goedert, Leondios G. Kostrikis · 2004 · AIDS
20. Long‐Term Decay of the HIV‐1 Reservoir in HIV‐1–Infected Children Treated with Highly Active Antiretroviral Therapy
    Marisa Zanchetta, Ann Sarah Walker, Nicoletta Burighel, Domenico Bellanova, Osvalda Rampon, Carlo Giaquinto, Anita De Rossi · 2006 · The Journal of Infectious Diseases
21. Latency and viral persistence in HIV-1 infection
    Janet D'Angelo Siliciano, Robert F. Siliciano · 2000 · Journal of Clinical Investigation
22. The cell biology of HIV-1 latency and rebound
    Uri R. Mbonye, Jonathan Karn · 2024 · Retrovirology
23. Piecewise HIV virus dynamic model with CD4+ T cell count-guided therapy: I
    Sanyi Tang, Yanni Xiao, Ning Wang, Hulin Wu · 2012 · Journal of Theoretical Biology
24. Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation
    Miguel Stevens, Jan M. Balzarini, Oriana Tabarrini, Graciela Andreï, Robert Snoeck, Violetta Cecchetti, Arnaldo Fravolini, Erik De Clercq, Christophe C. Pannecouque · 2005 · Journal of Antimicrobial Chemotherapy
25. HIV-1 latency in actively dividing human T cell lines
    Rienk E. Jeeninga, Ellen M. Westerhout, Marja L van Gerven, Ben Berkhout · 2008 · Retrovirology
26. Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques
    Julia Bergild McBrien, Andrew Kam Ho Wong, Erick White, Diane G. Carnathan, John H. Lee, Jeffrey T. Safrit, Thomas H. Vanderford, Mirko Paiardini, Ann Chahroudi, Guido Silvestri · 2020 · Journal of Virology
27. Human Immunodeficiency Virus Reactivation by Phorbol Esters or T-Cell Receptor Ligation Requires both PKCα and PKCθ
    Sergey A. Trushin, Gary D. Bren, Susana Asin, Kevin N. Pennington, Carlos V. Payá, Andrew D. Badley · 2005 · Journal of Virology
28. Long HIV Type 1 Reverse Transcripts Can Accumulate Stably within Resting CD4 + T Cells While Short Ones Are Degraded
    William J. Swiggard, Una O’Doherty, David McGain, Deepa Jeyakumar, Michael H. Malim · 2004 · AIDS Research and Human Retroviruses
29. Fitness Landscape of Human Immunodeficiency Virus Type 1 Protease Quasispecies
    Guerau Fernández, Bonaventura Clotet, Miguel Ángel Martı́nez · 2006 · Journal of Virology
30. Reconsidering targeted toxins to eliminate HIV infection: You gotta have HAART
    Edward A. Berger, Bernard Moss, Ira H Pastan · 1998 · Proceedings of the National Academy of Sciences
31. The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for Postintegration Silencing of HIV-1 Gene Expression in Latently Infected Cells
    Annabelle Gérard, Emmanuel Ségéral, Monica Naughtin, Ahmed Abdouni, Bénédicte Charmeteau-De Muylder, Rémi Cheynier, Jean‐Christophe Rain, Stéphane Emiliani · 2015 · Cell Host & Microbe
32. An HIV-1 Replication Pathway Utilizing Reverse Transcription Products That Fail To Integrate
    Benjamin Trinité, Eric C. Ohlson, Igor Voznesensky, Shashank P. Rana, Chi Ngai Chan, Saurabh Mahajan, Jason Alster, Sean A. Burke, Dominik Wodarz, David N. Levy · 2013 · Journal of Virology
33. Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality
    Sarah B. Laskey, Christopher W. Pohlmeyer, Katherine M. Bruner, Robert F. Siliciano · 2016 · PLoS Pathogens
34. The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1
    María Rosa López‐Huertas, Laura Jiménez-Tormo, Nadia Madrid-Elena, Carolina Gutiérrez, Sara Rodríguez-Mora, Mayte Coiras, José Alcamı́, Santiago Moreno · 2017 · Scientific Reports
35. A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG)
    Huachao Huang, Weili Kong, Maxime Junior Jean, Guillaume N. Fiches, Dawei Zhou, Tsuyoshi Hayashi, Jianwen Que, Netty G. Santoso, Jian Kang Zhu · 2019 · Nucleic Acids Research
36. Estimating the approximate analytical solution of HIV viral dynamic model by using homotopy analysis method
    Parvaiz Ahmad Naik, Jian Zu, Mohammad Ghoreishi · 2019 · Chaos Solitons & Fractals
37. Human Immunodeficiency Virus (HIV)–Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy
    Jenny L. Anderson, Gabriela Khoury, Rémi Fromentin, Ajantha E. Solomon, Nicolas Chomont, Elizabeth Sinclair, Jeffrey M. Milush, Wendy Hartogensis, Peter Bacchetti, Michael Roche et al. · 2019 · The Journal of Infectious Diseases
38. Morphological Analysis and Lentiviral Transduction of Fetal Monkey Bone Marrow-Derived Mesenchymal Stem Cells
    Chang I Lee, Donald B. Kohn, Jason E. Ekert, Alice F. Tarantal · 2003 · Molecular Therapy
39. Evolution in the sensitivity of quantitative HIV-1 viral load tests
    Bryan R Cobb, Jeffrey E. Vaks, Tri Do, Regis A. Vilchez · 2011 · Journal of Clinical Virology
40. Productive HIV Infection of Resting CD4 + T Cells: Role of Lymphoid Tissue Microenvironment and Effect of Immunomodulating Agents
    Audrey L. Kinter, Anitha Moorthy, Robert Wilson Jackson, Anthony S. Fauci · 2003 · AIDS Research and Human Retroviruses
41. Peripheral Blood Dendritic Cells Are Not a Major Reservoir for HIV Type 1 in Infected Individuals on Virally Suppressive HAART
    Miguel A. Otero, Giuseppe Nunnari, Daniela Leto, Julie Sullivan, Fengxiang Wang, Ian Frank, Yan Xu, Charvi A. Patel, Geethanjali Dornadula, Joseph Kulkosky et al. · 2003 · AIDS Research and Human Retroviruses
42. Complement Mediates the Binding of HIV to Erythrocytes
    Eliška Potluková, Olivier Gasser, Salima Sadallah, Jameel M. Inal, Guillaume Bourgeois, Ingrid Ziekau, Thomas Klimkait, Jürg Alfred Schifferli · 2004 · The Journal of Immunology
43. Abnormal intracellular IL-2 and interferon-gamma (IFN-γ) production as HIV-1-associated markers of immune dysfunction
    Mike Westby, J. Blake Marriott, Mary Guckian, Sharon Cookson, Phillip Hay, Angus George Dalgleish · 1998 · Clinical & Experimental Immunology
44. HIV Protease Inhibition: Limited Recent Progress and Advances in Understanding Current Pitfalls
    Fátima Rodríguez‐Barrios, Federico Gago · 2004 · Current Topics in Medicinal Chemistry
45. Viral load and burden modification following early antiretroviral therapy of primary HIV-1 infection
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46. Single-molecule immunoassay technology: Recent advances
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47. The Effects of Latent Infection on the Dynamics of HIV
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48. Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific
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49. In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus
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50. Biphasic decay kinetics suggest progressive slowing in turnover of latently HIV-1 infected cells during antiretroviral therapy
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51. HIV Antibody Characterization as a Method to Quantify Reservoir Size During Curative Interventions
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52. Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation
    Krista A. Delviks‐Frankenberry, Olga A. Nikolaitchik, Ryan C. Burdick, Robert J. Gorelick, Brandon F. Keele, Wei-Shau Hu, Vinay K. Pathak · 2016 · PLoS Pathogens
53. HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication
    Sheila Marie Keating, Christopher D. Pilcher, Vivek Jain, Mila Lebedeva, Dylan Hampton, Mohamed Abdel‐Mohsen, Xutao Deng, Gary Murphy, Alex Welte, Shelley N. Facente et al. · 2017 · The Journal of Infectious Diseases
54. Diverse effects of interferon alpha on the establishment and reversal of HIV latency
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55. PCR-mediated recombination: A general method applied to construct chimeric infectious molecular clones of plasma-derived HIV–1 RNA
    Guowei Fang, Barbara Weiser, Aloise Visosky, Timothy H. Moran, Harold Burger · 1999 · Nature Medicine
56. Simian immunodeficiency virus model of HIV induced central nervous system dysfunction
    E.M.E. Burudi, Howard S. Fox · 2001 · Advances in virus research
57. First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody
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58. HIV Infection Enhances TRAIL-Induced Cell Death in Macrophage by Down-Regulating Decoy Receptor Expression and Generation of Reactive Oxygen Species
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59. How does HIV cause AIDS? The homing theory
    Miles W. Cloyd, Jenny J-Y Chen, Liqiang Wang · 2000 · Molecular Medicine Today
60. Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β
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61. HIV-1 Vpr reactivates latent HIV-1 provirus by inducing depletion of class I HDACs on chromatin
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62. Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus
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63. Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy
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64. Perspectives on Analytical Treatment Interruptions in People Living with HIV and Their Health Care Providers in the Landscape of HIV Cure-Focused Studies
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65. HIV-1 Proviral Transcription and Latency in the New Era
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66. HIV-1 gp120 induces NFAT nuclear translocation in resting CD4+ T-cells
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67. Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods
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68. HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations
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69. Extensive HIV-1 Intra-Host Recombination Is Common in Tissues with Abnormal Histopathology
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70. NFAT5 Regulates HIV-1 in Primary Monocytes via a Highly Conserved Long Terminal Repeat Site
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71. Gene transcription in HIV infection
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72. HIV time hierarchy: winning the war while, loosing all the battles
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73. Administration of Recombinant Rhesus Interleukin-12 during Acute Simian Immunodeficiency Virus (SIV) Infection Leads to Decreased Viral Loads Associated with Prolonged Survival in SIVmac251-Infected Rhesus Macaques
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74. Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells
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75. Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor
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76. Finding a cure for HIV: will it ever be achievable?
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77. Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation
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78. Imaging HIV-1 Genomic DNA from Entry through Productive Infection
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79. Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028—study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation
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80. Persistent HIV-1 Viremia on Antiretroviral Therapy: Measurement and Mechanisms
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81. Epigenetic Mechanisms of HIV-1 Persistence
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82. Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir
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83. CD4 lymphocytes in the blood of HIV+ individuals migrate rapidly to lymph nodes and bone marrow: support for homing theory of CD4 cell depletion
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84. Targeting lymph nodes with liposomes bearing anti-HLA-DR Fab′ fragments
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85. Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART
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86. Defective HIV-1 genomes and their potential impact on HIV pathogenesis
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87. Effect of Suberoylanilide Hydroxamic Acid (SAHA) Administration on the Residual Virus Pool in a Model of Combination Antiretroviral Therapy-Mediated Suppression in SIVmac239-Infected Indian Rhesus Macaques
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88. High frequencies of resting CD4 + T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections
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89. The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape
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90. Low Inducibility of Latent Human Immunodeficiency Virus Type 1 Proviruses as a Major Barrier to Cure
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91. Exosomes in HIV infection
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92. Productive infection of double-negative T cells with HIV in vivo
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93. Rapid dissemination of a pathogenic simian/human immunodeficiency virus to systemic organs and active replication in lymphoid tissues following intrarectal infection
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94. The Roles of Cellular Factors in Retroviral Integration
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95. CD8+ cell noncytotoxic anti-human immunodeficiency virus response inhibits expression of viral RNA but not reverse transcription or provirus integration
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96. Immunization with Both T Cell-Dependent and T Cell-Independent Vaccines Augments HIV Viral Load Secondarily to Stimulation of Tumor Necrosis Factor α
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97. HIV Medicine 2005
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98. Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach
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99. Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration
    Sylvain Thierry, Soundasse Munir, Eloïse Thierry, Frédéric Subra, Hervé Leh, Alessia Zamborlini, Dyana T. Saenz, David N. Levy, Paul Lesbats, Ali Saı̈b et al. · 2015 · Retrovirology
100. Advancements in Developing Strategies for Sterilizing and Functional HIV Cures
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