Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

Gal, Andreas, Li, Yun, Thompson, Debra A., Weir, Jessica, Orth, Ulrike, Jacobson, Samuel G., Apfelstedt-Sylla, Eckart, Vollrath, Douglas·2000·Nature Genetics

DOI 10.1038/81555

Cited by (680)

Items 301–400 of 680

Layer-specific blood-flow MRI of retinitis pigmentosa in RCS rats
Guang Li, Bryan H. De La Garza, Yen‐Yu Ian Shih, Eric R. Muir, Timothy Q. Duong · 2012 · Experimental Eye Research
Non-viral gene therapy for GDNF production in RCS rat: the crucial role of the plasmid dose
Elodie Touchard, Peter Heiduschka, Marianne Berdugo, Laura Kowalczuk, Pascal Bigey, Sabine Chahory, Christelle Gandolphe, J.C. Jeanny, Francine Béhar‐Cohen · 2011 · Gene Therapy
TUDCA Promotes Phagocytosis by Retinal Pigment Epithelium via MerTK Activation
Hiromi Murase, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara · 2015 · Investigative Ophthalmology & Visual Science
ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis
Feiye Guo, Ying Ding, Nora Blanca Caberoy, Gabriela Alvarado, Feng Wang, Rui Chen, Wei Li · 2015 · Molecular Biology of the Cell
MRI reveals differential regulation of retinal and choroidal blood volumes in rat retina
Govind Nair, Yoji Tanaka, Moon Kim, Darin E. Olson, Peter M. Thulé, Machelle T. Pardue, Timothy Q. Duong · 2010 · NeuroImage
Ferroxidase Hephaestin's Cell-Autonomous Role in the Retinal Pigment Epithelium
Natalie Wolkow, Delu Song, Ying Song, Sally Chu, Majda Hadziahmetovic, Jennifer C. Lee, Jared Iacovelli, Steven F. Grieco, Joshua L. Dunaief · 2012 · American Journal Of Pathology
Core circadian clock genes Per1 and Per2 regulate the rhythm in photoreceptor outer segment phagocytosis
Nemanja Milićević, Ouafa Ait-Hmyed Hakkari, Udita Bagchi, Cristina Sandu, Aldo Jongejan, Perry D. Moerland, Jacoline B. ten Brink, David Hicks, Arthur A B Bergen, Marie‐Paule Felder‐Schmittbuhl · 2021 · The FASEB Journal
Regulation of phagocytosis by TAM receptors and their ligands
Lu, Qingxian, Li, Qiutang, Lu, Qingjun · 2010 · Frontiers in Biology
Human retinal pigment epithelial cells express the long pentraxin PTX3.
Je Moon Woo, Min‐Young Kwon, Da-Yong Shin, Young-Ho Kang, Narae Hwang, Su Wol Chung · 2013 · Europe PMC (PubMed Central)
Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis
Motoya Sato, Hiroshi Ohguro, Ikuyo Ohguro, Kazuhisa Mamiya, Yoshiko Takano, Hitoshi Yamazaki, Tomomi Metoki, Yasuhiro Miyagawa, Fotoshi Ishikawa, Mitsuru Nakazawa · 2003 · Biochemical and Biophysical Research Communications
Enhancing RPE Cell-Based Therapy Outcomes for AMD: The Role of Bruch's Membrane
Janosch Peter Heller, Keith R G Martin · 2014 · Translational Vision Science & Technology
Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation
Christo Kole, Laurence Klipfel, Ying Yang, Vanessa Ferracane, Frédéric Blond, Sacha Reichman, Géraldine Millet-Puel, Emmanuelle Clérin, Najate Aït-Ali, Delphine Pagan et al. · 2017 · Molecular Therapy
Neural Stem Cells Derived by Small Molecules Preserve Vision
Bin Lü, Catherine W. Morgans, Sergey Girman, Jing Luo, Jiagang J. Zhao, Hongjun Du, Sharon Lim, Sheng Ding, Clive Niels Svendsen, Kang Zhang et al. · 2013 · Translational Vision Science & Technology
Nonsense mutation in MERTK causes autosomal recessive retinitis pigmentosa in a consanguineous Pakistani family
A. Shahzadi, Sheikh Riazuddin, Shahbaz Ali, D. Li, S. N. Khan, Tayyab Husnaın, Javed Akram, Paul A. Sieving, James Fielding Hejtmancik, Sheikh Riazuddin · 2010 · British Journal of Ophthalmology
Ocular genetics: current understanding
Ian M. MacDonald, Mai Tran, Maria A. Musarella · 2004 · Survey of Ophthalmology
Phosphoinositides in Retinal Function and Disease
Theodore G. Wensel · 2020 · Cells
Intraocular Gene Transfer of Ciliary Neurotrophic Factor Rescues Photoreceptor Degeneration in RCS Rats
Shun‐Ping Huang, Po-Kang Lin, Jorn‐Hon Liu, Chin-Ni Khor, Yih-Jing Lee · 2004 · Journal of Biomedical Science
Effects of Calcium Ion, Calpains, and Calcium Channel Blockers on Retinitis Pigmentosa
Mitsuru Nakazawa · 2010 · Journal of Ophthalmology
Magnetic resonance imaging of the retina
Timothy Q. Duong, Eric R. Muir · 2009 · Japanese Journal of Ophthalmology
Cell-based therapy for retina degeneration: The promise of a cure
Frederic P. Gaillard, Yves Sauvé · 2007 · Vision Research
Recombinant Sendai Virus-mediated Gene Transfer into Adult Rat Retinal Tissue: Efficient Gene Transfer by Brief Exposure
Yasuhiro Ikeda, Yoshikazu Yonemitsu, Taiji Sakamoto, Tatsuro Ishibashi, Hikaru Ueno, Atsushi Kato, Yoshiyuki Nagai, Masayuki Fukumura, Hajime Inomata, Mamoru Hasegawa et al. · 2002 · Experimental Eye Research
Screening of the MERTK gene for mutations in Japanese patients with autosomal recessive retinitis pigmentosa.
Asako Tada, Yuko Wada, Hajime Sato, Toshitaka Itabashi, Miyuki Kawamura, Makoto Tamai, Kohji Nishida · 2006 · PubMed
Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells
Bo Tian, Ahmad Al‐Moujahed, Peggy Bouzika, Yijun Hu, Shoji Notomi, Pavlina Tsoka, Joan W. Miller, Haijiang Lin, Demetrios G. Vavvas · 2017 · Scientific Reports
Death begets a new beginning
Lidia Bosurgi, Lindsey D. Hughes, Carla Vanina Rothlin, Sourav Ghosh · 2017 · Immunological Reviews
Mechanistical retinal drug targets and challenges
Kai Kaarniranta, Heping Xu, Anu Kauppinen · 2018 · Advanced Drug Delivery Reviews
Rescue of Photoreceptors by BDNF Gene Transfer UsingIn VivoElectroporation in the RCS Rat of Retinitis Pigmentosa
Meng Zhang, Xiaofen Mo, Yuan Fang, Wenyi Guo, Jihong Wu, Shenghai Zhang, Qian Huang · 2009 · Current Eye Research
Microglia Mediate Synaptic Material Clearance at the Early Stage of Rats With Retinitis Pigmentosa
Juncai He, Congjian Zhao, Jiaman Dai, Chuan Huang Weng, Baishijiao Bian, Yu Long Gong, Lingling Ge, Yajie Fang, Hui Liu, Haiwei Xu et al. · 2019 · Frontiers in Immunology
Retinitis Pigmentosa and Allied Disorders
Richard G. Weleber, Kevin Gregory-Evans · 2006 · Elsevier eBooks
Role of αvβ5 Integrin in Regulating Phagocytosis by the Retinal Pigment Epithelium
Silvia C. Finnemann · 2003 · Advances in experimental medicine and biology
Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome
Ramachandra Rao, Sriganesh, Pfeffer, Bruce A., Más Gómez, Néstor, Skelton, Lara A., Keiko, Ueda, Sparrow, Janet R., Rowsam, Aryn M., Mitchell, Claire H., Fliesler, Steven J. · 2018 · Autophagy
Disease-associated microglial activation prevents photoreceptor degeneration by suppressing the accumulation of cell debris and neutrophils in degenerating rat retinas
Juncai He, Yan Fu, Lingling Ge, Jiaman Dai, Yajie Fang, Yijian Li, Xianliang Gu, Zui Tao, Ting Zou, Minghui Li et al. · 2022 · Theranostics
Current Understanding of the Mechanisms for Clearance of Apoptotic Cells—A Fine Balance
Lois Hawkins, Andrew Devitt · 2013 · Journal of Cell Death
Regenerative nanomedicine and the treatment of degenerative retinal diseases
Marco A. Zarbin, Carlo David Montemagno, James F. Leary, Robert H. Ritch · 2011 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
Severe autosomal recessive retinitis pigmentosa maps to chromosome 1p13.3–p21.2 between D1S2896 and D1S457 but outside ABCA4
Qingjiong Zhang, Fareeha Zulfiqar, Xueshan Xiao, Saima Riazuddin, Radha Ayyagari, Farooq Sabar, Raphael Caruso, Paul A. Sieving, Sheikh Riazuddin, James Fielding Hejtmancik · 2005 · Human Genetics
Retinal degeneration is delayed by tissue factor pathway inhibitor-2 in RCS rats and a sodium-iodate-induced model in rabbits
Ryo Obata, Yasuo Yanagi, Yasuhiro Tamaki, Kenta Hozumi, Masato Mutoh, Y. Tanaka · 2004 · Eye
Transplantation of rat embryonic stem cell-derived retinal progenitor cells preserves the retinal structure and function in rat retinal degeneration
Zepeng Qu, Yuan Guan, Lu Cui, Jian Song, Junjie Gu, Hanzhi Zhao, Lei Xu, Lixia Lü, Ying Jin, Guo‐Tong Xu · 2015 · Stem Cell Research & Therapy
The Immune Privileged Retina Mediates an Alternative Activation of J774A.1 Cells
Chun Ho Lau, Andrew W. Taylor · 2009 · Ocular Immunology and Inflammation
Identification of recurrent and novel mutations in TULP1 in Pakistani families with early-onset retinitis pigmentosa.
Muhammad Ajmal, Muhammad Imran Khan, Shazia Micheal, Waqas Ahmed, Ashfa Shah, Hanka Venselaar, Habib Bokhari, Aisha Azam, Nadia Khalida Waheed, Rob W.J. Collin et al. · 2012 · Europe PMC (PubMed Central)
Phagocytosis of apoptotic cells in mammals, Caenorhabditis Elegans and drosophila Melanogaster: molecular mechanisms and physiological consequences
Nathalie C. Franc · 2002 · Frontiers in bioscience
Gene expression changes in the retina following subretinal injection of human neural progenitor cells into a rodent model for retinal degeneration.
Melissa K Jones, Bin Lü, Mehrnoosh Saghizadeh, Shaomei Wang · 2016 · PubMed Central
Rev-Erbα and Photoreceptor Outer Segments modulate the Circadian Clock in Retinal Pigment Epithelial Cells
Nemanja Milićević, Nadia Mazzaro, Ivanka de Bruin, Esmée Wils, Jacoline B. ten Brink, Anneloor L.M.A. ten Asbroek, Jorge Mendoza, Arthur A B Bergen, Marie‐Paule Felder‐Schmittbuhl · 2019 · Scientific Reports
Human pluripotent stem cells: A toolbox to understand and treat retinal degeneration
Lise Morizur, Elise Herardot, Christelle Monville, Karim Ben M’Barek · 2020 · Molecular and Cellular Neuroscience
Acellularized Uvea Hydrogel as Novel Injectable Platform for Cell‐Based Delivering Treatment of Retinal Degeneration and Optimizing Retinal Organoids Inducible System
Guilan Li, Sheng Liu, Wenfei Chen, Zhijian Jiang, Yuanting Luo, Dongliang Wang, Yingfeng Zheng, Yizhi Liu · 2022 · Advanced Healthcare Materials
Ionic Dysregulatory Phenotyping of Pathologic Retinal Thinning with Manganese-Enhanced MRI
Bruce A. Berkowitz, Marius Gradianu, Stephen Schafer, Ying Jin, Andre Porchia, Raymond Iezzi, Robin A. Roberts · 2008 · Investigative Ophthalmology & Visual Science
Use of Iris Pigment Epithelium to Replace Retinal Pigment Epithelium in Age-Related Macular Degeneration
Hui Cai · 2006 · Archives of Ophthalmology
Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation
Valeria Chichagova, Dean Hallam, Joseph Collin, Adriana Buskin, Gabriele Christine Saretzki, Lyle Armstrong, Patrick Yu‐Wai‐Man, Majlinda Lako, DAVID H. STEEL · 2017 · Scientific Reports
Optical Coherence Tomography of Animal Models of Retinitis Pigmentosa: From Animal Studies to Clinical Applications
Mitsuru Nakazawa, Aiko Hara, Sei-ichi Ishiguro · 2019 · BioMed Research International
Folate-Modified Photoelectric Responsive Polymer Microarray as Bionic Artificial Retina to Restore Visual Function
Zhenghang Yu, Weijian Chen, Xi Liu, Qiu-Yu Xia, Yinuo Yang, Mei Dong, Jiahao Liu, Huaijin Guan, Cheng Sun, Fude Feng et al. · 2020 · ACS Applied Materials & Interfaces
Regenerative Nanomedicine for Vision Restoration
Marco A. Zarbin, Timothy Arlow, Robert H. Ritch · 2013 · Mayo Clinic Proceedings
Retinal metabolic state of the proline-23-histidine rat model of retinitis pigmentosa
Mónica L. Acosta, Yea-Seul Shin, Sarah Ready, Erica Lucy Fletcher, David L. Christie, Michael Kalloniatis · 2009 · American Journal of Physiology-Cell Physiology
Die Rolle des retinalen Pigmentepithels im Rahmen visueller Funktionen
Olaf Strauß · 2009 · Der Ophthalmologe
The Phagocytosis of OS is Mediated by the PI3-Kinase Linked Tyrosine Kinase Receptor, Mer, and is Stimulated by Gas6
Michael O. Hall, Brian J. Agnew, Toshka A. Abrams, Barry L. Burgess · 2003 · Advances in experimental medicine and biology
Having an Old Friend for Dinner: The Interplay between Apoptotic Cells and Efferocytes
Austin Le Lam, Bryan Heit · 2021 · Cells
MERTK-Mediated LC3-Associated Phagocytosis (LAP) of Apoptotic Substrates in Blood-Separated Tissues: Retina, Testis, Ovarian Follicles
Marina Yéfimova, Célia Ravel, Antoine Dominique Rolland, Nicolas Bourmeyster, Bernard Jégou · 2021 · Cells
Systemic taurine treatment affords functional and morphological neuroprotection of photoreceptors and restores retinal pigment epithelium function in RCS rats
Ana Martínez-Vacas, Johnny Di Pierdomenico, Alejandro Gallego‐Ortega, Francisco Javier Valiente‐Soriano, Manuel Vidal‐Sanz, Serge A. Picaud, María Paz Villegas‐Pérez, Diego García‐Ayuso · 2022 · Redox Biology
Spatiotemporal Live-Cell Analysis of Photoreceptor Outer Segment Membrane Ingestion by the Retinal Pigment Epithelium Reveals Actin-Regulated Scission
Ankita Umapathy, Gil Torten, Antonio E. Paniagua, Julie Chung, Madeline Tomlinson, Caleb Lim, David S. Williams · 2023 · Journal of Neuroscience
Inherited Retinal Dystrophy in Mer Knockout Mice
Jacque L. Duncan, Haidong Yang, Douglas Vollrath, Douglas Yasumura, Michael T. Matthes, Nikolaus Trautmann, Aimee V. Chappelow, Wei Feng, Henry Shelton Earp, Glenn K. Matsushima et al. · 2003 · Advances in experimental medicine and biology
Effects of Subretinal Electrical Stimulation in Mer-KO Mice
Julie A. Mocko, Moon Kim, Amanda E. Faulkner, Yang Cao, Vincent T. Ciavatta, Machelle T. Pardue · 2011 · Investigative Ophthalmology & Visual Science
MERTK polymorphisms associated with risk of haematological disorders among Korean SLE patients
Hyun Sub Cheong, S. O. Lee, Chan‐Bum Choi, Yoon‐Kyoung Sung, Hyoung Doo Shin, Sang‐Cheol Bae · 2006 · Lara D. Veeken
The Retinal Pigment Epithelium
Olaf Strauß · 2011 · Europe PMC (PubMed Central)
Concise Review: Human Induced Pluripotent Stem Cell Models of Retinitis Pigmentosa
Ana Artero‐Castro, Dunja Lukovic, Pavla Jendelová, Slaven Erceg · 2018 · Stem Cells
Bisretinoids mediate light sensitivity resulting in photoreceptor cell degeneration in mice lacking the receptor tyrosine kinase Mer
Jin Zhao, Keiko Ueda, Marina Riera, Hye Jin Kim, Janet R. Sparrow · 2018 · Journal of Biological Chemistry
Functional Voltage-Gated Calcium Channels Are Present in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium
Iina Korkka, Taina Viheriälä, Kati Juuti‐Uusitalo, Hannele Uusitalo‐Järvinen, Heli Skottman, Jari Hyttinen, Soile Nymark · 2018 · Stem Cells Translational Medicine
Changes in Retinal Pigment Epithelial Gene Expression Induced by Rod Outer Segment Uptake
Itay Chowers, Yoonhee Kim, Ronald H. Farkas, Tushara L. Gunatilaka, Abigail S. Hackam, Peter A. Campochiaro, Silvia C. Finnemann, Donald J. Zack · 2004 · Investigative Ophthalmology & Visual Science
Accumulation of Neurocan, a Brain Chondroitin Sulfate Proteoglycan, in Association with the Retinal Vasculature in RCS Rats
Yiqin Zhang, Uwe Rauch, Maria-Thereza R. Perez · 2003 · Investigative Ophthalmology & Visual Science
A course‐based undergraduate research experience in biochemistry that is suitable for students with various levels of preparedness
Shameka J. Shelby · 2019 · Biochemistry and Molecular Biology Education
Case of Stargardt Disease Caused by Uniparental Isodisomy
John H. Fingert · 2006 · Archives of Ophthalmology
The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function
Andrea García‐Llorca, Snæfríður Guðmundsdóttir Aspelund, Margret Helga Ogmundsdottir, Eirı́kur Steingrı́msson, Þór Eysteinsson · 2019 · Scientific Reports
Comparative Genomics for Detecting Human Disease Genes
Carol Moreno, Jozef Lazar, Howard J. Jacob, Anne E. Kwitek · 2008 · Advances in genetics
Synergistic neuroprotective effect via simian lentiviral vector‐mediated simultaneous gene transfer of human pigment epithelium‐derived factor and human fibroblast growth factor‐2 in rodent models of retinitis pigmentosa
Masanori Miyazaki, Yasuhiro Ikeda, Yoshikazu Yonemitsu, Yoshinobu Goto, Ri-ichiro Kohno, Yusuke Murakami, Makoto Inoue, Yasuji Ueda, Mamoru Hasegawa, Shozo Tobimatsu et al. · 2008 · The Journal of Gene Medicine
Cloning and Characterization of the Human Retina-Specific Gene MPP4, a Novel Member of the p55 Subfamily of MAGUK Proteins
Heidi Stöhr, Bernhard H. F. Weber · 2001 · Genomics
Gene therapy for retinal and choroidal diseases
Peter A. Campochiaro · 2002 · Expert Opinion on Biological Therapy
The Formation and Renewal of Photoreceptor Outer Segments
XU Jingjin, Chengtian Zhao, Yunsi Kang · 2024 · Cells
MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors
Shameka J. Shelby, Kecia L. Feathers, Anna M. Ganios, Lin Jia, Jason M. L. Miller, Debra A. Thompson · 2015 · Experimental Eye Research
Constant illumination causes spatially discrete dopamine depletion in the normal and degenerate retina
Anthony Vugler, Peter Redgrave, Nicola Hewson-Stoate, John Greenwood, Peter J. Coffey · 2007 · Journal of Chemical Neuroanatomy
OFD1, as a Ciliary Protein, Exhibits Neuroprotective Function in Photoreceptor Degeneration Models
Juan Wang, Xin Chen, Fang Wang, Jieping Zhang, Peng Li, Zongyi Li, Jingying Xu, Furong Gao, Caixia Jin, Haibin Tian et al. · 2016 · PLoS ONE
Multimodal Delivery of Isogenic Mesenchymal Stem Cells Yields Synergistic Protection from Retinal Degeneration and Vision Loss
Benjamin Bakondi, Sergey Girman, Bin Lu, Shaomei Wang · 2016 · Stem Cells Translational Medicine
New concepts in macrophage ontogeny in the adult neural retina
Daniel R. Saban · 2018 · Cellular Immunology
Union Makes Strength: A Worldwide Collaborative Genetic and Clinical Study to Provide a Comprehensive Survey of RD3 Mutations and Delineate the Associated Phenotype
Isabelle Perrault, Alejandro Estrada‐Cuzcano, Irma López, Susanne Kohl, Shiqiang Li, Francesco Testa, Renate C. Zekveld-Vroon, Xia Wang, Esther Pomares, Jean Andorf et al. · 2013 · PLoS ONE
Can Phage Display Be Used as a Tool to Functionally Identify Endogenous Eat-Me Signals in Phagocytosis?
Nora Blanca Caberoy, Yixiong Zhou, Wei Li · 2009 · SLAS DISCOVERY
Intravitreal Silicon-Based Quantum Dots as Neuroprotective Factors in a Model of Retinal Photoreceptor Degeneration
Jeffrey L. Olson, Raúl Vélez-Montoya, Naresh Mandava, Conrad R. Stoldt · 2012 · Investigative Ophthalmology & Visual Science
Gene Therapy in Hereditary Retinal Dystrophies: The Usefulness of Diagnostic Tools in Candidate Patient Selections
Mariaelena Malvasi, Lorenzo Casillo, Filippo Avogaro, Alessandro Abbouda, Enzo Maria Vingolo · 2023 · International Journal of Molecular Sciences
A Perspective on the Mechanism of the Light-Rise of the Electrooculogram
Paul A. Constable · 2014 · Investigative Ophthalmology & Visual Science
Axl and Mer Receptor Tyrosine Kinases: Distinct and Nonoverlapping Roles in Inflammation and Cancer?
Ian Dransfield, Sarah L. Farnworth · 2016 · Advances in experimental medicine and biology
Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium
Grażyna Palczewska, Akiko Maeda, Marcin Golczak, Eisuke Arai, Zhiqian Dong, Lindsay Perusek, Brian M. Kevany, Krzysztof Palczewski · 2016 · Journal of Biological Chemistry
Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration
Jing Yang, Bin Lü, Qiang Feng, Jorge S. Alfaro, Po-Hsuen Chen, Joseph Loscalzo, Wenbin Wei, Yingyi Zhang, Shi‐Jiang Lu, Shaomei Wang · 2021 · Translational Vision Science & Technology
Intravenous infusion of small umbilical cord mesenchymal stem cells could enhance safety and delay retinal degeneration in RCS rats
Qingling Liang, Qiyou Li, Bangqi Ren, Zheng Qin Yin · 2022 · BMC Ophthalmology
Self-assembly of protein aggregates in ageing disorders: the lens and cataract model
John I. Clark · 2013 · Philosophical Transactions of the Royal Society B Biological Sciences
Pluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE Perspective
Sonal Dalvi, Chad A. Galloway, Ruchira Singh · 2019 · Advances in experimental medicine and biology
Targeted disruption of the endogenous zebrafish rhodopsin locus as models of rapid rod photoreceptor degeneration.
Christopher Paul Zelinka, Mailin Sotolongo-Lopez, James M. Fadool · 2018 · Europe PMC (PubMed Central)
Gene Correction Recovers Phagocytosis in Retinal Pigment Epithelium Derived from Retinitis Pigmentosa-Human-Induced Pluripotent Stem Cells
Ana Artero‐Castro, Kathleen R. Long, Andrew Roger Bassett, Almudena Ávila‐Fernández, Marta Cortón, Antonio Vidal‐Puig, Pavla Jendelová, Francisco Javier Rodríguez-Jiménez, Eleonora Clemente, Carmen Ayuso et al. · 2021 · International Journal of Molecular Sciences
Omics in Ophthalmology: Advances in Genomics and Precision Medicine for Leber Congenital Amaurosis and Age-Related Macular Degeneration
Anneke I. den Hollander · 2016 · Investigative Ophthalmology & Visual Science
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment
Gregory R. Hamm, Gareth Adam Maglennon, Beth Williamson, Ruth Macdonald, Ann Doherty, Stewart A. Jones, Jayne Harris, James Blades, Alexander R. Harmer, Peter Barton et al. · 2022 · Archives of Toxicology
Systemic immunotherapy delays photoreceptor cell loss and prevents vascular pathology in Royal College of Surgeons rats.
Grazyna Adamus, Shaomei Wang, Madison Kyger, Aneta H. Worley, Bin Lü, Gregory G. Burrows · 2012 · Europe PMC (PubMed Central)
Mimicking Retinal Development and Disease With Human Pluripotent Stem Cells
Divya Sinha, Jenny Phillips, M. Joseph Phillips, David M. Gamm · 2016 · Investigative Ophthalmology & Visual Science
Developing Cell-Based Therapies for RPE-Associated Degenerative Eye Diseases
Karim Ben M’Barek, Walter Habeler, Florian Régent, Christelle Monville · 2019 · Advances in experimental medicine and biology
Measuring the cone contribution to the ERG b-wave to assess function and predict anatomical rescue in RCS rats
Isabel Pinilla, Raymond D. Lund, B. Lu, Yves Sauvé · 2004 · Vision Research
The pigmented epithelium, a bright partner against photoreceptor degeneration
Joaquín Letelier, Paola Bovolenta, Juan Ramón Martínez‐Morales · 2017 · Journal of Neurogenetics
Génétique des rétinites pigmentaires : classification métabolique et corrélations phénotype/génotype
Cecilia G. Maubaret, Christian Hamel · 2005 · Journal Français d Ophtalmologie
Two-Front War on Cancer—Targeting TAM Receptors in Solid Tumour Therapy
Agata Mikołajczyk, Filip Mituła, Delfina Popiel, Bozena Kaminska, Maciej Wieczorek, Jerzy Pieczykolan · 2022 · Cancers