Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

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Items 601–680 of 680

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  2. Influenza A infection accelerates disease-associated microglia formation during physiological aging
    Rogan A. Grant, Constance E. Runyan, Grace Minogue, Joshua S. Stoolman, Satoshi Watanabe, Fei Chen, Karolina J. Senkow, Luisa Cusick, Maxwell J. Schleck, Radmila A. Nafikova et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Ca2+ Channels in the Retinal Pigment Epithelium
    Olaf Strauß · 2008 · Humana Press eBooks
  4. Elucidating the Signalling Pathway of Mer Tyrosine Kinase Receptor in Efferocytosis
    Ekenedelichukwu Azu · 2014 · Scholarship@Western (Western University)
  5. Magnetic Resonance Imaging of the Rat Retina: a Dissertation
    Govind Bhagavatheeshwaran · 2008 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  6. Em busca de novos métodos de tratamento para a retinose pigmentar causada por mutações na rodopsina.
    Fernanda Balen · 2012
  7. The Soluble Form of the Axl Receptor Tyrosine Kinase
    Carl Johan Ekman · 2010 · Lund University Publications (Lund University)
  8. Insight into Leber congenital amaurosis: potential for gene therapy
    Dania Qatarneh, Hemal Mehta, Vickie Lee · 2011 · Expert Review of Ophthalmology
  9. Generation of retinal pigment epithelium from human induced pluripotent stem cells showed polarized secretion of VEGF and PEDF.
    Hiroyuki Kamao, Junko Ishida, Taiji Suda, Junichi Kiryu · 2013 · Institutional Repositories DataBase (IRDB)
  10. Exclusion of Influences of ARMS2 Polymorphisms on the Central Visual Field in Retinitis Pigmentosa
    Hidetaka Masahara, Mitsuru Nakazawa, Eiji Kawamura, Shuichiro Eguchi · 2013 · Ophthalmologica
  11. Phagocytosis of Retinal Rod and Cone Photoreceptors
    Mitra Farnoodian, James B. Kinter, Saeed Yadranji Aghdam, Ismail S. Zaitoun, M Sorenson Christine, Su Khoh‐Reiter, Sharon A. Sokolowski, Bart A. Jessen, Mark Gordon Evans, Deepak Dalvie et al. · 2015
  12. Gene-Based Medicines Targeting Genetic Defects Directly and Molecular Pathologies Common to Multiple Forms of Disease
    Pete Humphries, Marian M. Humphries, Lawrence C. S. Tam, Gwyneth Jane Farrar, Paul F. Kenna, Matthew Campbell, Anna‐Sophia Kiang · 2012 · SpringerBriefs in genetics
  13. Plasma Biomarkers for Age-Related Macular Degeneration
    Jiaqian Ni · 2009 · EngagedScholarship @ Cleveland State University (Cleveland State University)
  14. Pharmacological Aspects of Nilvadipine-Induced Preservation of Retinal Degeneration in RCS Rat Analyzed by mRNA Profiling Assay
    Futoshi Ishikawa, Hiroshi Ohguro, Ikuyo Maruyama, Yoshiko Takano, Hitoshi Yamazaki, Tomomi Metoki, Yasuhiro Miyagawa, Motoya Sato, Kazuhisa Mamiya, Mitsuru Nakazawa · 2003 · Springer eBooks
  15. MERTK-mediated Signaling in the Retinal Pigment Epithelium: Insights into the Mechanism of RPE Phagocytosis.
    Shameka J. Shelby · 2012 · Deep Blue (University of Michigan)
  16. The role of MerTK and BAFF in dendritic cell-B cell interactions
    Paul Reid Gohlke · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  17. GENETIC COUNSELLING IN VISUAL AND AUDITORY DISORDERS EL ASESORAMIENTO GENÉTICO EN LOS DÉFICITS VISUALES Y AUDITIVOS
    Millán Jm, Elena Aller, Elena Grau · 2008
  18. The cause of retinitis pigmentosa and new therapy under development for its treatment
    Kenji Sakamoto, Asami Mori, Tsutomu Nakahara, Kunio Ishii · 2010 · Folia Pharmacologica Japonica
  19. Dietary Antioxidants, αvβ5 Integrin, and Ocular Protection
    Saumil Sethna, Silvia C. Finnemann · 2014 · Elsevier eBooks
  20. Investigating retinal pathology in patients carrying m.3243A>G mutation using human induced pluripotent stem cells
    Valeria Chichagova · 2017
  21. Quantitative evaluation of retinal degeneration in royal college of surgeons rats by contrast enhanced ultrahigh resolution optical coherence tomography
    Min-Jyun Su, Po-Wei Chen, Chang-Chih Ke, Shih‐Hwa Chiou, Wen‐Chuan Kuo, Jia‐Pu Syu · 2018 · Ophthalmic Technologies
  22. Magnetic Resonance Imaging of the Rat Retina
    Govind Bhagavatheeshwaran · 2008 · Digital WPI
  23. Cell Delivery: Surgical Approaches
    Odysseas Georgiadis, Peter J. Coffey, Lyndon da Cruz · 2019 · Stem cell biology and regenerative medicine
  24. Changed Interaction of L-Type Ca2+ Channels and Receptor Tyrosine Kinase in RPE Cells from RCS Rats
    Rita Rosenthal, Olaf Strauß · 2001 · Springer eBooks
  25. The Role of MERTK in Central Inflammatory Demyelination
    Chris Dwyer · 2020 · Minerva Access (University of Melbourne)
  26. Generation of a homozygous CRISPR/Cas9-mediated knockout H9 hESC subline for the MERTK locus
    Xiangcheng Tang, Jialing Fu, Zhigang Chen, Lixia Luo, David Wan‐Cheng Li, Wei Shan Li · 2021 · Stem Cell Research
  27. Monitoring of vascular degeneration in a rat retina model by OCT angiography
    Jia‐Pu Syu, Chen-Chieh Chang, Wen‐Chuan Kuo, Shih‐Hwa Chiou · 2021 · Optics in the Life Sciences
  28. Arap1 Loss Causes RPE Phagocytic Dysfunction and Subsequent Photoreceptor Death
    Andy Shao, A. J. Lopez, Jiajia Chen, A. Tham, Seanne Javier, Alejandra Quiroz, S. Frick, E. Levine, K. C. Kent Lloyd, B. Leonard et al. · 2021 · bioRxiv
  29. Retinal Degeneration Secondary to MERTK Mutations: Potential Candidate for Gene Therapy
    John H. Shen-Sampas, Stephanie Duret, Jacque L. Duncan · 2021 · International Ophthalmology Clinics
  30. Immunogenetics of acute anterior Uveitis and comparison to Ankylosing Spondylitis
    Xiu‐Feng Huang · 2021 · Queensland University of Technology
  31. Leber Congenital Amaurosis and Early-Onset Retinal Dystrophy
    Bart Peter Leroy · 2014 · Springer eBooks
  32. Protein-tyrosine kinase (PTK, not ETK, WZC)
    Dietmar Schomburg, Ida Schomburg, Antje Chang · 2007 · Springer eBooks
  33. Lexikalischer Teil
    Regine Witköwski, Otto Prokop, Eva Ullrich, Gundula Thiel · 2003 · Springer eBooks
  34. MERTK
    Sarwar Zahid, Kari E. H. Branham, Dana Schlegel, Mark Edward Pennesi, Michel Michaelides, John R. Heckenlively, Thiran Jayasundera · 2018 · Springer eBooks
  35. Defining novel physiological roles for cardiac-residen Macrophages
    José Ángel Nicolás Ávila · 2020
  36. Faculty Opinions recommendation of mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.
    Andrius Kazlauskas, Sarah Melissa P Jacobo · 2011 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  37. 901 Inhibition of GAS6/MerTK signaling by novel MerTK antibody, 20A77, exerts significant anti-tumor efficacy with little retinal degeneration in mice
    Atsushi Sawada, Masayoshi Toyoura, Aki Takaiwa, Toshikazu Inoue, Koji Nakamura · 2022 · Regular and Young Investigator Award Abstracts
  38. A novel quantification method for RPE phagocytosis using a VLC-PUFA-based strategy
    Fangyuan Gao, Emily Tom, Stephanie A. Lieffrig, Silvia C. Finnemann, Dorota Skowronska‐Krawczyk · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Desarrollo de tratamientos experimentales para pacientes con retinosis pigmentaria
    Lady L. Lozano B., Luis A. Cervantes A. · 2023 · Archivos de la Sociedad Española de Oftalmología
  40. RETRACTED: Novel loss of function mutation in MERTK gene, the first report of an Iranian family with an autosomal recessive inheritance of retinitis pigmentosa
    Reza Vazifehmand, Foroozandeh Monem Homaie, Alireza Massiha, Dhuha Saeed Ali, Mohsen Najafi · 2023 · Research Square · Retracted
  41. RPE-Phagozytose
    Claudia Müller, Silvia C. Finnemann · 2024 · Springer eBooks
  42. RPE und Gentherapie
    Knut Stieger, Birgit Lorenz · 2024 · Springer eBooks
  43. A novel GCaMP6f-RCS rat model for studying electrical stimulation in the degenerated retina
    Tamar Azrad Leibovitch, Nairouz Farah, Amos Markus, Yossi Mandel · 2024 · Frontiers in Cell and Developmental Biology
  44. MERTK INHIBITOR-ASSOCIATED RETINAL TOXICITY IN A HUMAN
    Anne Strong Caldwell, Dallin C. Milner, Nihaal B. Mehta, Alejandro I Marin, Zafar S. Gill, Niranjan Manoharan · 2024 · Retinal Cases & Brief Reports
  45. Honoring Professor Andreas Gal
    Elias I. Traboulsi, Brian P. Brooks · 2025 · Ophthalmic Genetics
  46. Loss of ciliary proteins IFT20 and IFT88 results in defective phagocytosis and metabolism in the RPE
    Peter Andreas Matthiessen, Lotta Elisabeth Wagner, Karsten Boldt, Gunnar Glaßer, Ingo Lieberwirth, Emeline F. Nandrot, Helen May‐Simera · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  47. CLINICAL FEATURES OF MERTK-RELATED RETINOPATHY
    Arif O. Khan · 2025 · Retina
  48. Chemical reprogramming of fibroblasts into retinal pigment epithelium cells for vision restoration
    Sha-Sha Li, Hui Liu, Shao-Hui Pan, Zhengbiao Zhu, Shun Zhang, Jia-Hang Li, Ying-Hao Yao, Xinyu Wang, Na Gao, Xiao-Yu Liu et al. · 2025 · Nature Communications
  49. The role of Axl/Mertk/Tyro3 receptor tyrosine kinases in the clearance of apoptotic cells
    Heather Seitz · 2019 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  50. Cell therapy limits loss of vision in an animal model of retinal degenerative disease
    Trevor J. McGill · 2004 · Open ULeth Scholarship (OPUS) (University of Lethbridge)
  51. Leber Congenital Amaurosis and other autosomal recessive retinal dystrophies: A clinical and molecular genetic study
    Phillip Moradi · 2014 · UCL Discovery (University College London)
  52. Additional file 7 of Definition of the transcriptional units of inherited retinal disease genes by meta-analysis of human retinal transcriptome data
    Karla Alejandra Ruiz-Ceja, Dalila Capasso, Michele Pinelli, Eugenio Del Prete, Diego Carrella, di Bernardo, Diego, Sandro Banfi · 2023 · Figshare
  53. Additional file 1 of Unravelling the genetic basis of retinal dystrophies in Pakistani consanguineous families
    Marwan, Muhammad, Muhammad Dawood, Mukhtar Ullah, Irfan Ullah Shah, Khan, Niamat, Muhammad Taimur Hassan, Karam, Muhammad, Rawlins, Lettie E., Emma L. Baple, Andrew H. Crosby et al. · 2024 · Figshare
  54. CD14 and TLR4 contribute to the circadian regulation of retinal phagocytosis as co-receptors
    Leila Dhaoui Hajem, Julie Enderlin, Quentin Rieu, Sara Krim, Jennyfer C Parnasse, Clément Materne, Geneviève Marcelin, Thierry Huby, Emeline F. Nandrot · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  55. Mapping the intellectual landscape and emerging trends of retinitis pigmentosa research
    Li Xiao, Li-Xuan Tang, Min Ai, Yuting Yang, Ying Deng, Jing Lu, Ya-Sha Zhou, Jing Xiong, Qinghua Peng · 2026 · Frontiers in Medicine
  56. Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations
    Alba Videla Ristol, Ana Martínez-Vacas, David García‐Bernal, Manuel Vidal‐Sanz, María Paz Villegas‐Pérez, Diego García‐Ayuso, Johnny Di Pierdomenico · 2026 · Acta Ophthalmologica
  57. Myeloid HDAC3 deletion protects against traumatic optic injury
    Rami Ahmad Shahror, Carol Morris, Ashlynn Cunningham, Piyanan Chuesiang, Abdelrahman Y. Fouda · 2026 · Cell Death Discovery
  58. Identification de nouvelles voies de signalisation activées dans les léiomyosarcomes
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  59. Signalisation et ciblage thérapeutique du récepteur tyrosine kinase AXL dans les cancers
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  62. Circadian regulation of the retinal pigment epithelium–photoreceptor complex
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  63. Automatisation de la différenciation des cellules souches pluripotentes humaines en cellules de l’épithélium pigmentaire rétinien et modélisation des symptômes rétiniens associés à la mutation d’APC
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  65. Expression des récepteurs TAM dans les cellules immunitaires humaines et identification de MerTK comme cible thérapeutique dans le microenvironnement tumoral
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    Simone Mortal, Jesús Planagumà, Enric Pérez-Parets, Pablo Loza‐Álvarez · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  69. NAD+ modulates mitochondrial vulnerability in MERTK-associated models of retinitis pigmentosa
    Lujia Feng, Yuwen Wen, Ting Zhang, Xiaohua Zhuo, Yantao Wei, Lixian Liu, Zhaohao Huang, Guoming Zhang, Lu Chen, Yong Du et al. · 2026 · Nature Communications
  70. Retinal network dysfunction precedes structural degeneration in severe GUCA1A cone-rod dystrophy
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  71. Loss of ATRAID in Late-Onset, Non-Syndromic Retinitis Pigmentosa
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  73. Optimizing stimulation parameters: transpalpebral and transbrain electrical stimulation for retinal protection in RCS rats
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  74. Olfactory ensheathing cell-derived extracellular vesicles protect the degenerated retinal pigment epithelium by delivering phagocytosis-related proteins
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