Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

Gal, Andreas, Li, Yun, Thompson, Debra A., Weir, Jessica, Orth, Ulrike, Jacobson, Samuel G., Apfelstedt-Sylla, Eckart, Vollrath, Douglas·2000·Nature Genetics

DOI 10.1038/81555

Cited by (680)

Items 201–300 of 680

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Carlo Rivolta · 2002 · Archives of Ophthalmology
Tyro3 modulates Mertk-associated retinal degeneration
Vollrath, Douglas, Yasumura, Douglas, Benchorin, Gillie, Matthes, Michael T., Feng, Wei, Nguyen, Natalie M., Sedano, Cecilia D., Calton, Melissa A., LaVail, Matthew M. · 2015 · PLoS Genetics
Preservation of retinal morphology and functions in royal college surgeons rat by nilvadipine, a Ca(2+) antagonist.
Hitoshi Yamazaki, Hiroshi Ohguro, Tadao Maeda, Ikuyo Maruyama, Yoshiko Takano, Tomomi Metoki, Mitsuru Nakazawa, Hajime Sawada, Mari Dezawa · 2002 · PubMed
Proteasome Inhibitors Activate Autophagy Involving Inhibition of PI3K-Akt-mTOR Pathway as an Anti-Oxidation Defense in Human RPE Cells
Bingrong Tang, Jingjing Cai, Lin Ning Sun, Yiping Li, Jia Qu, Barbara Joy Snider, Shengzhou Wu · 2014 · PLoS ONE
Structural and molecular bases of rod photoreceptor morphogenesis and disease
Theodore G. Wensel, Zhixian Zhang, Ivan Anastassov, Jared C. Gilliam, Feng He, Michael F. Schmid, Michael A. Robichaux · 2016 · Progress in Retinal and Eye Research
Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration
Sayuri Mizukoshi, Mitsuru Nakazawa, Kota Sato, Taku Ozaki, Tomomi Metoki, Sei-ichi Ishiguro · 2010 · Experimental Eye Research
Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina
Aiden Eblimit, Thanh-Minh T. Nguyen, Yiyun Chen, Julián Esteve-Rudd, Hua Zhong, Stef J.F. Letteboer, Jeroen van Reeuwijk, David L. Simons, Qian Ding, Ka Man Wu et al. · 2014 · Human Molecular Genetics
Ectopic synaptogenesis during retinal degeneration in the royal college of surgeons rat
Yuandong Peng, Toshihiko Senda, Yingjie Hao, Kiyoshi Matsuno, Fulton Wong · 2003 · Neuroscience
Characterisation of severe rod-cone dystrophy in a consanguineous family with a splice site mutation in the MERTK gene
Peter Charbel Issa, Hanno J. Bolz, Inga Ebermann, E. Domeier, Frank Gerhard Holz, Hendrik P. N. Scholl · 2009 · British Journal of Ophthalmology
RDH12 retinopathy: novel mutations and phenotypic description.
2011 · Europe PMC (PubMed Central)
Possible sources of neuroprotection following subretinal silicon chip implantation in RCS rats
Machelle T. Pardue, Michael J Phillips, Hang Yin, Alcides Fernandes, Yian C. Cheng, Alan Y. Chow, Sherry L. Ball · 2005 · Journal of Neural Engineering
Visual cycle proteins: Structure, function, and roles in human retinal disease
Andrew T. C. Tsin, Brandi S Betts-Obregon, Jeffery G. Grigsby · 2018 · Journal of Biological Chemistry
Fundus Autofluorescence in Patients with Leber Congenital Amaurosis
Hendrik P. N. Scholl, Victor N. Chong, Anthony G. Robson, Graham E. Holder, Anthony T. Moore, Alan C. Bird · 2004 · Investigative Ophthalmology & Visual Science
Role of bestrophin-1 in store-operated calcium entry in retinal pigment epithelium
Néstor Más Gómez, Ernst R. Tamm, Olaf Strauβ · 2012 · Pflügers Archiv - European Journal of Physiology
Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography
Renee C. Ryals, Michael D. Andrews, Shreya Datta, Aaron S. Coyner, Cody M. Fischer, Yuquan Wen, Mark Edward Pennesi, Trevor J. McGill · 2017 · Investigative Ophthalmology & Visual Science
Gas6 binding to photoreceptor outer segments requires gamma-carboxyglutamic acid (Gla) and Ca(2+) and is required for OS phagocytosis by RPE cells in vitro.
Michael O. Hall, Martin S. Obin, Anne L. Prieto, Barry L. Burgess, Toshka A. Abrams · 2002 · PubMed
Cortical visual functions can be preserved by subretinal RPE cell grafting in RCS rats
Sergey Girman, S Wang, Raymond D. Lund · 2003 · Vision Research
Sustained tetracycline‐regulated transgene expression in vivo in rat retinal ganglion cells using a single type 2 adeno‐associated viral vector
S. Folliot, D. Briot, H. Conrath, N. Provost, Y. Chérel, P. Moullier, F. Rolling · 2003 · Journal of Gene Medicine
TAM receptors in phagocytosis: Beyond the mere internalization of particles
Tal Burstyn‐Cohen, Roberta Fresia · 2023 · Immunological Reviews
Gene supplementation therapy for recessive forms of inherited retinal dystrophies
Alexander J. Smith, James W. Bainbridge, Robin R. Ali · 2011 · Gene Therapy
Structural insights into the inhibited states of the Mer receptor tyrosine kinase
Xudong Huang, P.J. Finerty, John R. Walker, Christine Butler-Cole, Masoud Vedadi, Matthieu Schapira, Sirlester A. Parker, Benjamin E. Turk, Debra A. Thompson, Sirano Dhe‐Paganon · 2008 · Journal of Structural Biology
Bruch's membrane aging decreases phagocytosis of outer segments by retinal pigment epithelium.
Kai Sun, Hui Cai, Tongalp H. Tezel, David C. Paik, Elizabeth R. Gaillard, Lucian V. Del Priore · 2007 · PubMed
GAS6/TAM Pathway Signaling in Hemostasis and Thrombosis
Luke A. Law, Douglas K. Graham, Jorge Di Paola, Brian R. Branchford · 2018 · Frontiers in Medicine
Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice
Akiko Maeda, Grażyna Palczewska, Marcin Golczak, Hideo Kohno, Zhiqian Dong, Tadao Maeda, Krzysztof Palczewski · 2014 · Proceedings of the National Academy of Sciences
Nanocarriers of nanotechnology in retinal diseases
Ali M. Al-Halafi · 2014 · Saudi Journal of Ophthalmology
Layer‐specific anatomical, physiological and functional MRI of the retina
Timothy Q. Duong, Machelle T. Pardue, Peter M. Thulé, Darin E. Olson, Haiying Cheng, Govind Nair, Yingxia Li, Moon Kim, Xiaodong Zhang, Qiang Shen · 2008 · NMR in Biomedicine
Human iPSC derived disease model of MERTK-associated retinitis pigmentosa
Dunja Lukovic, Ana Artero‐Castro, Ana Belén García-Delgado, María de los Angeles Martín Bernal, Noelia Luna-Peláez, Andrea Díez-Lloret, Rocío Perez Espejo, Kunka Kamenarova, Laura Fernández‐Sánchez, Nicolás Cuenca et al. · 2015 · Scientific Reports
MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL
Kathryn Tworkoski, James T. Platt, Antonella Bacchiocchi, Marcus Bosenberg, Titus J. Boggon, David F. Stern · 2013 · Pigment Cell & Melanoma Research
Hereditary Retinal Dystrophy
Hohman, Thomas C. · 2016 · Handbook of Experimental Pharmacology
Tyrosine-Mutant AAV8 Delivery of Human MERTK Provides Long-Term Retinal Preservation in RCS Rats
Wen‐Tao Deng, Astra Dinculescu, Qiuhong Li, Sanford L. Boye, Jie Li, Marina S. Gorbatyuk, Jijing Pang, Vince A. Chiodo, Michael T. Matthes, Douglas Yasumura et al. · 2012 · Investigative Ophthalmology & Visual Science
Early Events in Retinal Degeneration Caused by Rhodopsin Mutation or Pigment Epithelium Malfunction: Differences and Similarities
Johnny Di Pierdomenico, Diego García‐Ayuso, Isabel Pinilla, Nicolás Cuenca, Manuel Vidal‐Sanz, Marta Agudo‐Barriuso, María Paz Villegas‐Pérez · 2017 · Frontiers in Neuroanatomy
Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis
Anna Tutusaus, Montserrat Marı́, José Tomás Ortiz-Pérez, Gerry A. F. Nicolaes, Albert Morales, Pablo Garcı́a de Frutos · 2020 · Cells
Phagocytosis of apoptotic cells in mammals Caenorhabditis Elegans and drosophila Melanogaster molecular mechanisms and physiological consequences
Nathalie C. Franc · 2002 · Frontiers in bioscience
A novel MERTK deletion is a common founder mutation in the Faroe Islands and is responsible for a high proportion of retinitis pigmentosa cases.
Elsebet Østergaard, Morten Dunø, Mustafa Batbayli, Kaj Vilhelmsen, Thomas Rosenberg · 2011 · Europe PMC (PubMed Central)
Macrophages, Metabolism and Heterophagy in the Heart
José Ángel Nicolás-Ávila, Laura Pena-Couso, Pura Muñoz-Cánoves, Andrés Hidalgo · 2022 · Circulation Research
Mitochondria impairment correlates with increased sensitivity of aging RPE cells to oxidative stress
Yuan He, Jian Ge, Janice M. Burke, Roland L. Myers, Zhi Dong, Joyce Tombran‐Tink · 2010 · Journal of ocular biology, diseases, and informatics
Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs
Conor M. Ramsden, Britta Nommiste, Amelia Lane, Amanda‐Jayne F. Carr, Michael Barry Powner, Matthew J. K. Smart, Li Chen, Manickam Nick Muthiah, Andrew R. Webster, Anthony T. Moore et al. · 2017 · Scientific Reports
Mitochondrial Decay and Impairment of Antioxidant Defenses in Aging RPE Cells
Yuan He, Joyce Tombran‐Tink · 2009 · Advances in experimental medicine and biology
Contribution of rod and cone pathways to the dark-adapted electroretinogram (ERG) b-wave following retinal degeneration in RCS rats
Isabel Pinilla, Raymond D. Lund, Yves Sauvé · 2004 · Vision Research
Impact of genomics on research in the rat
Jozef Lazar, Carol Moreno, Howard J. Jacob, Anne E. Kwitek · 2005 · Genome Research
TAM Receptor Signalling and Demyelination
Michele D. Binder, Trevor John Kilpatrick · 2009 · Neurosignals
Partial preservation of rod and cone ERG function following subretinal injection of ARPE-19 cells in RCS rats
Yves Sauvé, Isabel Pinilla, Raymond D. Lund · 2005 · Vision Research
Endogenous Gas6 and Ca2+-channel activation modulate phagocytosis by retinal pigment epithelium
Michael Karl, Wolfram Kroeger, Soenke Wimmers, Vladimir M. Milenkovic, Monika Valtink, Katrin Engelmann, Olaf Strauß · 2008 · Cellular Signalling
The Retinal Pigment Epithelium
Morten la Cour, Tongalp H. Tezel · 2005 · Advances in organ biology
An Unusual Presentation of Macular Corneal Dystrophy Associated with Uniparental Isodisomy and a Novel Leu173Pro Mutation
Vivek S. Yellore, Barış Sönmez, Michael C. Chen, Sylvia A. Rayner, Eugene J-M.A. Thonar, Anthony John Aldave · 2007 · Ophthalmic Genetics
mTOR Signalling Pathway: A Potential Therapeutic Target for Ocular Neurodegenerative Diseases
Yipin Wang, Nicholas Siu Kay Fung, Wai‐Ching Lam, Acy Lo · 2022 · Antioxidants
The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium
Guoxin Ying, Karsten Boldt, Marius Ueffing, Cecilia D. Gerstner, Jeanne M. Frederick, Wolfgang Baehr · 2018 · Journal of Biological Chemistry
A hybrid P3HT-Graphene interface for efficient photostimulation of neurons
Mattia Lorenzo DiFrancesco, Elisabetta Colombo, Ermanno D. Papaleo, José Fernando Maya‐Vetencourt, Giovanni Manfredi, Guglielmo Lanzani, Fabio Benfenati · 2020 · Carbon
Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration
Anna Salas, Anna Duarri, Laura Fontrodona, Diana Mora Ramírez, Anna Casajoana Badia, Helena Isla-Magrané, Bárbara Ferreira-de-Souza, Miguel Ángel Zapata, Ángel Raya, Anna Veiga et al. · 2021 · Molecular Therapy — Methods & Clinical Development
Lentiviral vectors for ocular gene therapy
Arsenijevic, Yvan, Berger, Adeline, Udry, Florian, Kostic, Corinne · 2022 · Pharmaceutics
Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation
Stephanie A. Lieffrig, Gavin Gyimesi, Yingyu Mao, Silvia C. Finnemann · 2023 · Immunological Reviews
Tyro3, Axl, and Mertk Receptor Signaling in Inflammatory Bowel Disease and Colitis-associated Cancer
Carla Vanina Rothlin, Jonathan A. Leighton, Sourav Ghosh · 2014 · Inflammatory Bowel Diseases
Nanomedicine for the treatment of retinal and optic nerve diseases
Marco A. Zarbin, Carlo David Montemagno, James F. Leary, Robert H. Ritch · 2012 · Current Opinion in Pharmacology
Photoreceptor phagocytosis is mediated by phosphoinositide signaling
Debarshi Mustafi, Brian M. Kevany, Christel Genoud, Xiaodong Bai, Krzysztof Palczewski · 2013 · The FASEB Journal
The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration
Lyndsay L. Leach, Nicholas J. Hanovice, Stephanie M. George, Ana E. Gabriel, Jeffrey M. Gross · 2021 · Proceedings of the National Academy of Sciences
A novel locus (RP33) for autosomal dominant retinitis pigmentosa mapping to chromosomal region 2cen-q12.1
Chen Zhao, Shasha Lu, Xiaolei Zhou, Xiumei Zhang, Kanxing Zhao, Catharina Larsson · 2006 · Human Genetics
Tubby regulates microglial phagocytosis through MerTK
Nora Blanca Caberoy, Gabriela Alvarado, Wei Li · 2012 · Journal of Neuroimmunology
Evaluation of Tyro3 Expression, Gas6-Mediated Akt Phosphorylation, and the Impact of Anti-Tyro3 Antibodies in Melanoma Cell Lines
Stephen J. Demarest, Jennifer L. Gardner, Michelle C. Vendel, Eric Ailor, Suzanne T. Szak, Flora Huang, Adam Doern, Xiangyang Tan, Weixing Yang, Dorre A. Grueneberg et al. · 2013 · Biochemistry
Diurnal rodents as pertinent animal models of human retinal physiology and pathology
Daniela M. Verra, Benjamin S. Sajdak, Dana K. Merriman, David Hicks · 2019 · Progress in Retinal and Eye Research
Early Onset Retinal Dystrophy Due to Mutations in<i>LRAT</i>: Molecular Analysis and Detailed Phenotypic Study
Dev Borman, Arundhati, Ocaka, Louise A., Mackay, Donna S., Ripamonti, Caterina, Henderson, Robert H., Moradi, Phillip, Hall, Georgina, Black, Graeme C., Robson, Anthony G., Holder, Graham E. et al. · 2012 · Investigative Opthalmology & Visual Science
Efferocytosis Creates a Tumor Microenvironment Supportive of Tumor Survival and Metastasis
2015 · Cancer Cell & Microenvironment
Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100 secretion and triglyceride accumulation in ARPE-19 cells
Tinghuai Wu, Jane Y. Tian, Roy G. Cutler, Richard S. Telljohann, David Bernlohr, Mark P. Mattson, James T. Handa · 2009 · Laboratory Investigation
A Web-Based Data Warehouse on Gene Expression in Human Malignant Melanoma
Balázs Győrffy, Hermann Lage · 2006 · Journal of Investigative Dermatology
Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins
Lourdes Valdés-Sánchez, Sofia M. Calado, Berta de la Cerda, Ana Aramburu, Ana Belén García-Delgado, Simone Massalini, Adoración Montero-Sánchez, Vaibhav Bhatia, Eduardo Rodríguez‐Bocanegra, Andrea Díez-Lloret et al. · 2019 · Molecular Medicine
Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency
Déborah Lew, Francesca Mazzoni, Silvia C. Finnemann · 2020 · Frontiers in Immunology
Mutation Screening of Multiple Genes in Spanish Patients with Autosomal Recessive Retinitis Pigmentosa by Targeted Resequencing
María González‐del Pozo, Salud Borrego, Isabel Barragán, Juan Ignacio Pieras, Javier Santoyo‐López, Nerea Matamala, Belén Naranjo, Joaquı́n Dopazo, Guillermo Antiñolo · 2011 · PLoS ONE
Pigment Epithelium-Derived Factor, a Protective Factor for Photoreceptors in Vivo
Federica Polato, S. Patricia Becerra · 2015 · Advances in experimental medicine and biology
Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival
Toshihiko Toyofuku, Satoshi Nojima, Takako Ishikawa, Hyota Takamatsu, Tohru Tsujimura, Akiyoshi Uemura, Junko Matsuda, Takaharu Seki, Atsushi Kumanogoh · 2012 · Genes & Development
Gene Therapy for MERTK-Associated Retinal Degenerations
Matthew M. LaVail, Douglas Yasumura, Michael T. Matthes, Haidong Yang, William W. Hauswirth, Wen‐Tao Deng, Douglas Vollrath · 2015 · Advances in experimental medicine and biology
Accumulation of oxidized lipid-protein complexes alters phagosome maturation in retinal pigment epithelium
George Hoppe, J. O'Neil, H. Hoff, Jonathan E. Sears · 2004 · Cellular and Molecular Life Sciences (CMLS)
Gas6 Binding to Photoreceptor Outer Segments Requires γ-Carboxyglutamic Acid (Gla) and Ca2+ and is Required for OS Phagocytosis by RPE Cells in vitro
Michael O. Hall, Martin S. Obin, Anne L. Prieto, Barry L. Burgess, Toshka A. Abrams · 2002 · Experimental Eye Research
Mertk in Daily Retinal Phagocytosis: A History in the Making
Emeline F. Nandrot, Eric M. Dufour · 2009 · Advances in experimental medicine and biology
Isolation and Culture of Primary Mouse Retinal Pigmented Epithelial Cells
Daniel Gibbs, David S. Williams · 2003 · Advances in experimental medicine and biology
Human umbilical tissue-derived cells rescue retinal pigment epithelium dysfunction in retinal degeneration
Jing Cao, Christopher Murat, Weijun An, Xiang Yao, John Lee, Sandra Santulli-Marotto, Ian R. Harris, George Inana · 2015 · Stem Cells
A Comprehensive Review of Mutations in the MERTK Proto-Oncogene
Célia Parinot, Emeline F. Nandrot · 2015 · Advances in experimental medicine and biology
Novel stem cell and gene therapy in diabetic retinopathy, age related macular degeneration, and retinitis pigmentosa
Parker E. Ludwig, S. Caleb Freeman, Adam C. Janot · 2019 · International Journal of Retina and Vitreous
MutT Homolog-1 Attenuates Oxidative DNA Damage and Delays Photoreceptor Cell Death in Inherited Retinal Degeneration
Yusuke Murakami, Yasuhiro Ikeda, Noriko Yoshida, Shoji Notomi, Toshio Hisatomi, Sugako Oka, Gabriele De Luca, Yoshikazu Yonemitsu, Margherita Bignami, Yusaku Nakabeppu et al. · 2012 · American Journal Of Pathology
PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells
Bulloj, Ayelen, Duan, Wei, Finnemann, Silvia C. · 2013 · Experimental Eye Research
Optical Coherence Tomography of Retinal Degeneration in Royal College of Surgeons Rats and Its Correlation with Morphology and Electroretinography
Kobu Adachi, Shizuka Takahashi, Kodai Yamauchi, Natsuki Mounai, Reiko Tanabu, Mitsuru Nakazawa · 2016 · PLoS ONE
A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface
Cynthia Tang, Jimin Han, Sonal Dalvi, Kannan Vrindavan Manian, Lauren Winschel, Stefanie Volland, Celia A. Soto, Chad A. Galloway, Whitney Spencer, Michael Roll et al. · 2021 · Communications Biology
Homozygous Mutation in MERTK Causes Severe Autosomal Recessive Retinitis Pigmentosa
Mohamed Ksantini, Estèle Lafont, Béatrice Bocquet, Isabelle Meunier, Christian Hamel · 2011 · European Journal of Ophthalmology
CORD9 a new locus for arCRD: mapping to 8p11, estimation of frequency, evaluation of a candidate gene.
Michael Danciger, J Hendrickson, J Lyon, Carmel Toomes, J.C. McHale, Gerald Allen Fishman, Chris F. Inglehearn, Samuel G. Jacobson, Debora B. Farber · 2001 · PubMed
Screening of a Large Cohort of Leber Congenital Amaurosis and Retinitis Pigmentosa Patients Identifies Novel LCA5 Mutations and New Genotype-Phenotype Correlations
Donna S. Mackay, Arundhati Dev Borman, Ruifang Sui, L. Ingeborgh van den Born, Eliot L. Berson, Louise Ocaka, Alice E. Davidson, John R. Heckenlively, Kari E. H. Branham, Huanan Ren et al. · 2013 · Human Mutation
Novel splice donor site mutation in MERTK gene associated with retinitis pigmentosa
Alejandro Brea‐Fernández, Esther Pomares, Marı́a Brión, Gemma Marfany, M J Blanco, Manuel Sánchez‐Salorio, Roser Gonzàlez‐Duarte, Ángel Carracedo · 2008 · British Journal of Ophthalmology
Identification and characterization of C6orf37, a novel candidate human retinal disease gene on chromosome 6q14
Pamela S. Lagali, Laura E. Kakuk, Irina B. Griesinger, PAUL W. K. WONG, Radha Ayyagari · 2002 · Biochemical and Biophysical Research Communications
Recognition and phagocytosis of apoptotic T cells by resident murine tissue macrophages require multiple signal transduction events
Bin Hu, Antonello Punturieri, Jill C. Todt, Joanne Sonstein, Timothy Polak, Jeffrey L. Curtis · 2002 · Journal of Leukocyte Biology
Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk -associated retinitis pigmentosa
María Elisa Mercau, Yemsratch T. Akalu, Francesca Mazzoni, Gavin Gyimesi, Emily J. Alberto, Yong Kong, Brian P. Hafler, Silvia C. Finnemann, Carla Vanina Rothlin, Sourav Ghosh · 2023 · Science Advances
Unoprostone reduces oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction, by activating BK channels.
Kazuhiro Tsuruma, Yuka Tanaka, Masamitsu Shimazawa, Yukihiko Mashima, Hideaki Hara · 2011 · Europe PMC (PubMed Central)
RNA-seq reveals transcriptome changes in goats following myostatin gene knockout
Lamei Wang, Bei Cai, Shiwei Zhou, Haijing Zhu, Lei Qu, Xiaolong Wang, Yulin Chen · 2017 · PLoS ONE
Screening of SPATA7 in Patients with Leber Congenital Amaurosis and Severe Childhood-Onset Retinal Dystrophy Reveals Disease-Causing Mutations
Donna S. Mackay, Louise Ocaka, Arundhati Dev Borman, Panagiotis I. Sergouniotis, Robert Henderson, Phillip Moradi, Anthony G. Robson, Dorothy Thompson, Andrew R. Webster, Anthony T. Moore · 2011 · Investigative Ophthalmology & Visual Science
Neuroprotective Effect of Hepatocyte Growth Factor against Photoreceptor Degeneration in Rats
Shigeki Machida, Michiko Tanaka, Takehisa Ishii, Kouji Ohtaka, Tomomi Takahashi, Yutaka Tazawa · 2004 · Investigative Ophthalmology & Visual Science
MERTK interactions with SH2-domain proteins in the retinal pigment epithelium
Shelby, Shameka J., Colwill, Karen, Dhe-Paganon, Sirano, Pawson, Tony, Thompson, Debra A. · 2013 · PLoS ONE
Tyro3, Axl, Mertk receptor-mediated efferocytosis and immune regulation in the tumor environment
Liwen Zhou, Glenn K. Matsushima · 2021 · International review of cytology
Enhanced HtrA2/Omi Expression in Oxidative Injury to Retinal Pigment Epithelial Cells and Murine Models of Neurodegeneration
Xiaoyan Ding, Mrinali M. Patel, Defen Shen, Alexandra A. Herzlich, Xiaoguang Cao, Rafael Villasmil, Kristina Klupsch, Jingsheng Tuo, Julian Downward, Chi‐Chao Chan · 2009 · Investigative Ophthalmology & Visual Science
Efficacy and Safety of Human Retinal Progenitor Cells
Ma’ayan Semo, Nasrin Haamedi, Lara Stevanato, D. A. Carter, Gary P. Brooke, Michael J. Young, Peter J. Coffey, John D. Sinden, Sara Patel, Anthony Vugler · 2016 · Translational Vision Science & Technology
Photobiomodulation with 670 nm light increased phagocytosis in human retinal pigment epithelial cells.
Shinichiro Fuma, Hiromi Murase, Yoshiki Kuse, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara · 2015 · Europe PMC (PubMed Central)
Association study between polymorphims in GAS6-TAM genes and carotid atherosclerosis
Begoña Hurtado, Nerea Abasolo-Zabalo, Xavier Muñoz, Nadia García, Yolanda Benavente, Francisco Javier Rubio, Pablo Garcı́a de Frutos, Jerzy Krupiński, Núria Sala · 2010 · Thrombosis and Haemostasis
Combination of retinal pigment epithelium cell‐conditioned medium and photoreceptor outer segments stimulate mesenchymal stem cell differentiation toward a functional retinal pigment epithelium cell phenotype
Chen Huang, Jing Zhang, Mingxin Ao, Ying Li, Chun Zhang, Yong-gen Xu, Xuemin Li, Wei Wang · 2011 · Journal of Cellular Biochemistry
Transplantation of Syngeneic Schwann Cells to the Retina of the Rhodopsin Knockout (Rho −/− ) Mouse
David Keegan, Paul F. Kenna, Marian M. Humphries, Peter Humphries, Ian Flitcroft, Peter J. Coffey, Ray D. Lund, Jean M. Lawrence · 2003 · Investigative Ophthalmology & Visual Science
Melanization and phagocytosis: implications for age related macular degeneration.
Rangaprasad Sarangarajan, Shireesh Apte · 2005 · PubMed