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Suppression of tumor growth through disruption of hypoxia-inducible transcription
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“gif" NDATA ITEM> ]> Cellular hypoxia triggers a multifaceted adaptive response that is primarily mediated by the heterodimeric transcription factor hypoxia-inducible facto”
BackgroundCarcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium
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Cited by
Targeting HIF-1 for cancer therapy
Semenza, G. L. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1187 · Cited by 6,717
Hypoxia — a key regulatory factor in tumour growth
Harris, A. L. (2002) · Nature Reviews Cancer · doi:10.1038/nrc704 · Cited by 5,177
Exploiting tumour hypoxia in cancer treatment
Brown, J. M., & Wilson, W. R. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1367 · Cited by 2,828
Regulation of angiogenesis by hypoxia: role of the HIF system
Pugh, C. W., & Ratcliffe, P. J. (2003) · Nature Medicine · doi:10.1038/nm0603-677 · Cited by 2,520
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
Semenza, G. L. (2010) · Oncogene · doi:10.1038/onc.2009.441 · Cited by 1,712
Metadata
- Authors
- Kung, A. L., Wang, S., Klco, J. M., Kaelin, W. G., & Livingston, D. M.
- Venue
- Nature Medicine
- Published
- 2000-12
- Volume
- 6
- Issue
- 12
- Pages
- 1335-1340
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1543662618
- Cited by
- 501
- References
- 7
- FWCI
- 15.92
- Type
- journal article
- Language
- en
- Open access
- closed
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