The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Update on Serologic Testing in Celiac Disease
Abstract
Contemporary serologic testing has revolutionized the field of celiac disease (CD). Highly accurate serologic assays have shown the prevalence of CD to be nearly 1:100 in many populations. These mostly ELISA (enzyme-linked immunosorbent assay)-based tests allow noninvasive screening and detection. However, the growing number of available serologic tests necessitates reevaluation of their predictive power as a single test or in combination. We review the available tests for CD, including antibodies against gliadin, endomysium, tissue transglutaminase, and deamidated gliadin, and the evidence for preferential use of specific tests in different settings. Despite several novel developments, standardized ELISA-based assays for IgA autoantibodies against tissue transglutaminase remain the test of choice for most populations. We discuss the need to develop tests for CD activity in order to assess the efficacy of upcoming nondietary therapies.
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Cites
Identification of tissue transglutaminase as the autoantigen of celiac disease
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Coeliac disease in the year 2000: exploring the iceberg
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Celiac Disease: From Pathogenesis to Novel Therapies
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Self-citationDubé, C., Rostom, A., Sy, R., Cranney, A., Saloojee, N., Garritty, C., Sampson, M., Zhang, L., Yazdi, F., Mamaladze, V., et al. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.02.014 · Cited by 604
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The diagnostic accuracy of serologic tests for celiac disease: A systematic review
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Cited by
The Oslo definitions for coeliac disease and related terms
Ludvigsson, J. F., Leffler, D. A., Bai, J. C., Biagi, F., Fasano, A., Green, P. H. R., Hadjivassiliou, M., Kaukinen, K., Kelly, C. P., Leonard, J. N., et al. (2013) · Gut · doi:10.1136/gutjnl-2011-301346 · Cited by 1,721
Self-citationLebwohl, B., Sanders, D. S., & Green, P. H. R. (2018) · The Lancet · doi:10.1016/s0140-6736(17)31796-8 · Cited by 1,065
Celiac disease: understanding the gluten-free diet
Bascuñán, K. A., Vespa, M. C., & Araya, M. (2017) · European Journal of Nutrition · doi:10.1007/s00394-016-1238-5 · Cited by 284
Nutritional constituents of pseudo cereals and their potential use in food systems: A review
Mir, N. A., Riar, C. S., & Singh, S. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.03.016 · Cited by 174
Outcome measures in coeliac disease trials: the Tampere recommendations
Ludvigsson, J. F., Ciacci, C., Green, P. H., Kaukinen, K., Korponay-Szabo, I. R., Kurppa, K., Murray, J. A., Lundin, K. E. A., Maki, M. J., Popp, A., et al. (2018) · Gut · doi:10.1136/gutjnl-2017-314853 · Cited by 100
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Metadata
- Authors
- Leffler, D. A., & Schuppan, D.
- Venue
- American Journal of Gastroenterology
- Published
- 2010-12
- Volume
- 105
- Issue
- 12
- Pages
- 2520-2524
- ISSN
- 0002-9270 (ISSN-L)
- OpenAlex
- W1968014632
- Cited by
- 356
- References
- 46
- FWCI
- 21.41
- Type
- journal article
- Language
- en
- Open access
- closed
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