Genomic copy number predicts esophageal cancer years before transformation

Fast and accurate short read alignment with Burrows-Wheeler transform

Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607 · see citing works

Regularization and Variable Selection Via the Elastic Net

Zou, H., & Hastie, T. (2005) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.1467-9868.2005.00503.x · Cited by 20,957 · see citing works

Regularization Paths for Generalized Linear Models via Coordinate Descent

Friedman, J., Hastie, T., & Tibshirani, R. (2010) · Journal of Statistical Software · doi:10.18637/jss.v033.i01 · Cited by 19,927 · see citing works

Cancer statistics, 2016

Siegel, R. L., Miller, K. D., & Jemal, A. (2016) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21332 · Cited by 16,003 · see citing works

pROC: an open-source package for R and S+ to analyze and compare ROC curves

Robin, X., Turck, N., Hainard, A., Tiberti, N., Lisacek, F., Sanchez, J.-C., & Müller, M. (2011) · BMC Bioinformatics · doi:10.1186/1471-2105-12-77 · Cited by 13,697 · see citing works

Integrated genomic characterization of oesophageal carcinoma

Sun, Q., Kelsen, D. P., Wiznerowicz, M., Lu, Y., Marra, M. A., Wan, Y., Weinhold, N., Wong, A. M., Carvalho, A. L., Luketich, J. D., et al. (2017) · Nature · doi:10.1038/nature20805 · Cited by 1,833 · see citing works

High burden and pervasive positive selection of somatic mutations in normal human skin

Martincorena, I., Roshan, A., Gerstung, M., Ellis, P., Van Loo, P., McLaren, S., Wedge, D. C., Fullam, A., Alexandrov, L. B., Tubio, J. M., et al. (2015) · Science · doi:10.1126/science.aaa6806 · Cited by 1,770 · see citing works

ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus

Shaheen, N. J., Falk, G. W., Iyer, P. G., & Gerson, L. B. (2015) · The American Journal of Gastroenterology · doi:10.1038/ajg.2015.322 · Cited by 1,498 · see citing works

Radiofrequency Ablation in Barrett's Esophagus with Dysplasia

Shaheen, N. J., Sharma, P., Overholt, B. F., Wolfsen, H. C., Sampliner, R. E., Wang, K. K., Galanko, J. A., Bronner, M. P., Goldblum, J. R., Bennett, A. E., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808145 · Cited by 1,434 · see citing works

British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus

Fitzgerald, R. C., di Pietro, M., Ragunath, K., Ang, Y. S., Kang, J.-Y., Watson, P. J., Trudgill, N. J., Patel, P., Kaye, P., Sanders, S., et al. (2013) · Gut · doi:10.1136/gutjnl-2013-305372 · Cited by 1,344 · see citing works

Somatic mutant clones colonize the human esophagus with age

Martincorena, I., Fowler, J. C., Wabik, A., Lawson, A. R. J., Abascal, F., Hall, M. W. J., Cagan, A., Murai, K., Mahbubani, K., Stratton, M. R., et al. (2018) · Science · doi:10.1126/science.aau3879 · Cited by 1,113 · see citing works

The evolutionary history of 2,658 cancers

Gerstung, M., Jolly, C., Leshchiner, I., Dentro, S. C., Gonzalez, S., Rosebrock, D., Mitchell, T. J., Rubanova, Y., Anur, P., Yu, K., et al. (2020) · Nature · doi:10.1038/s41586-019-1907-7 · Cited by 1,057 · see citing works

Prediction of acute myeloid leukaemia risk in healthy individuals

Abelson, S., Collord, G., Ng, S. W. K., Weissbrod, O., Mendelson Cohen, N., Niemeyer, E., Barda, N., Zuzarte, P. C., Heisler, L., Sundaravadanam, Y., et al. (2018) · Nature · doi:10.1038/s41586-018-0317-6 · Cited by 850 · see citing works

The landscape of somatic mutation in normal colorectal epithelial cells

Lee-Six, H., Olafsson, S., Ellis, P., Osborne, R. J., Sanders, M. A., Moore, L., Georgakopoulos, N., Torrente, F., Noorani, A., Goddard, M., et al. (2019) · Nature · doi:10.1038/s41586-019-1672-7 · Cited by 747 · see citing works

Genetic clonal diversity predicts progression to esophageal adenocarcinoma

Maley, C. C., Galipeau, P. C., Finley, J. C., Wongsurawat, V. J., Li, X., Sanchez, C. A., Paulson, T. G., Blount, P. L., Risques, R., Rabinovitch, P. S., et al. (2006) · Nature Genetics · doi:10.1038/ng1768 · Cited by 687 · see citing works

Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia

Phoa, K. N., van Vilsteren, F. G. I., Weusten, B. L. A. M., Bisschops, R., Schoon, E. J., Ragunath, K., Fullarton, G. M., di Pietro, M., Ravi, N., Visser, M., et al. (2014) · JAMA · doi:10.1001/jama.2014.2511 · Cited by 636 · see citing works

Addressing overdiagnosis and overtreatment in cancer: a prescription for change

Esserman, L. J., Thompson, I. M., Reid, B. J., Nelson, P. S., Ransohoff, D. F., Welch, H. G., Hwang, S. E., Berry, D. A., Kinzler, K. W., Black, W. C., et al. (2014) · The Lancet Oncology · doi:10.1016/s1470-2045(13)70598-9 · Cited by 506 · see citing works

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

Mitchell, T. J., Turajlic, S., Rowan, A., Nicol, D. L., Farmery, J. H. R., O’Brien, T., Martincorena, I., Tarpey, P. S., Angelopoulos, N., Yates, L. R., et al. (2018) · Cell · doi:10.1016/j.cell.2018.02.020 · Cited by 502 · see citing works

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues

Yizhak, K., Aguet, F., Kim, J., Hess, J. M., Kübler, K., Grimsby, J., Frazer, R., Zhang, H., Haradhvala, N. J., Rosebrock, D., et al. (2019) · Science · doi:10.1126/science.aaw0726 · Cited by 500 · see citing works

DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assemblyPreprint

Scheinin, I., Sie, D., Bengtsson, H. L., van de Wiel, M. A., Olshen, A. B., van Thuijl, H. F., Essen, H. F. H. V., Eijk, P. P., Rustenburg, F., Meijer, G. A., et al. (2014) · Genome Research · doi:10.1101/gr.175141.114 · Cited by 491 · see citing works

Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance

Secrier, M., Li, X., de Silva, N., Eldridge, M., Contino, G., Bornschein, J., MacRae, S., Grehan, N., O’Donovan, M., Miremadi, A., et al. (2016) · Nature Genetics · doi:10.1038/ng.3659 · Cited by 397 · see citing works

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Brunner, S. F., Roberts, N. D., Wylie, L. A., Moore, L., Aitken, S. J., Davies, S. E., Sanders, M. A., Ellis, P., Alder, C., Hooks, Y., et al. (2019) · Nature · doi:10.1038/s41586-019-1670-9 · Cited by 393 · see citing works

Paired exome analysis of Barrett's esophagus and adenocarcinoma

Stachler, M. D., Taylor-Weiner, A. N., Peng, S., McKenna, A., Agoston, A. T., Odze, R. D., Davison, J. M., Nason, K. S., Loda, M. F., Leshchiner, I., et al. (2015) · Nature Genetics · doi:10.1038/ng.3343 · Cited by 366 · see citing works

Predictors of progression in Barrett's esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression

Reid, B. J., Prevo, L. J., Galipeau, P. C., Sanchez, C. A., Longton, G., Levine, D. S., Blount, P. L., & Rabinovitch, P. S. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.04236.x · Cited by 364 · see citing works

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis

Weaver, J. M. J., Ross-Innes, C. S., Shannon, N. B., Lynch, A. G., Forshew, T., Barbera, M., Murtaza, M., Ong, C. J., Lao-Sirieix, P., Dunning, M., et al. (2014) · Nature Genetics · doi:10.1038/ng.3013 · Cited by 348 · see citing works

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation

Nilsen, G., Liestøl, K., Loo, P. V., Vollan, H. K. M., Brodtkorb, M., Rueda, O. M., Chin, S., Russell, R., Baumbusch, L. O., Caldas, C., et al. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-591 · Cited by 302 · see citing works

Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma

Ross-Innes, C. S., Becq, J., Warren, A., Cheetham, R. K., Northen, H., O’Donovan, M., Malhotra, S., di Pietro, M., Ivakhno, S., He, M., et al. (2015) · Nature Genetics · doi:10.1038/ng.3357 · Cited by 299 · see citing works

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis

Nones, K., Waddell, N., Wayte, N., Patch, A., Bailey, P. J., Newell, F., Holmes, O., Fink, J. L., Quinn, M. C. J., Tang, Y., et al. (2014) · Nature Communications · doi:10.1038/ncomms6224 · Cited by 274 · see citing works

Tracing Oncogene Rearrangements in the Mutational History of Lung Adenocarcinoma

Lee, J. J.-K., Park, S., Park, H., Kim, S., Lee, J., Lee, J., Youk, J., Yi, K., An, Y., Park, I. K., et al. (2019) · Cell · doi:10.1016/j.cell.2019.05.013 · Cited by 233 · see citing works

The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic

Frankell, A. M., Jammula, S., Li, X., Contino, G., Killcoyne, S., Abbas, S., Perner, J., Bower, L., Devonshire, G., Ococks, E., et al. (2019) · Nature Genetics · doi:10.1038/s41588-018-0331-5 · Cited by 227 · see citing works

A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Jin, Z., Cheng, Y., Gu, W., Zheng, Y., Sato, F., Mori, Y., Olaru, A., Paun, B. C., Yang, J. P., Kan, T., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0028 · Cited by 225 · see citing works

Barrett’s dysplasia and the Vienna classification: reproducibility, prediction of progression and impact of consensus reporting and p53 immunohistochemistry

Kaye, P., Haider, S. A., Ilyas, M., James, P. D., Soomro, I. N., Faisal, W., Catton, J. A., Parsons, S. L., & Ragunath, K. (2009) · Histopathology · doi:10.1111/j.1365-2559.2009.03288.x · Cited by 175 · see citing works

Aneuploidy and Overexpression of Ki67 and p53 as Markers for Neoplastic Progression in Barrett's Esophagus: A Case–Control Study

Sikkema, M., Kerkhof, M., Steyerberg, E. W., Kusters, J. G., van Strien, P. M. H., Looman, C. W., van Dekken, H., Siersema, P. D., & Kuipers, E. J. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.437 · Cited by 148 · see citing works

Detection of Mutations in Barrett’s Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma

Stachler, M. D., Camarda, N. D., Deitrick, C., Kim, A., Agoston, A. T., Odze, R. D., Hornick, J. L., Nag, A., Thorner, A. R., Ducar, M. D., et al. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.03.047 · Cited by 145 · see citing works

Temporal and Spatial Evolution of Somatic Chromosomal Alterations: A Case-Cohort Study of Barrett's Esophagus

Li, X., Galipeau, P. C., Paulson, T. G., Sanchez, C. A., Arnaudo, J., Liu, K., Sather, C. L., Kostadinov, R. L., Odze, R. D., Kuhner, M. K., et al. (2013) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-13-0289 · Cited by 144 · see citing works

Development and Validation of a Model to Determine Risk of Progression of Barrett’s Esophagus to Neoplasia

Parasa, S., Vennalaganti, S., Gaddam, S., Vennalaganti, P. R., Young, P. E., Gupta, N., Thota, P. N., Cash, B. D., Mathur, S. C., Sampliner, R. E., et al. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.12.009 · Cited by 138 · see citing works

Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus

Martinez, P., Timmer, M. R., Lau, C. T., Calpe, S., Sancho‐Serra, M. D. C., Straub, D., Baker, A., Meijer, S. L., ten Kate, F. J. W., Mallant–Hent, R. C., et al. (2016) · Nature Communications · doi:10.1038/ncomms12158 · Cited by 92 · see citing works

DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus

Alvi, M. A., Liu, X., O’Donovan, M., Newton, R., Wernisch, L., Shannon, N. B., Shariff, M. K., di Pietro, M., Bergman, J. J. G. H. M., Ragunath, K., et al. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-2880 · Cited by 75 · see citing works

Genetic progression of Barrett’s oesophagus to oesophageal adenocarcinoma

Gregson, E., Bornschein, J., & Fitzgerald, R. C. (2016) · British Journal of Cancer · doi:10.1038/bjc.2016.219 · Cited by 58 · see citing works

Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels

Martinez, P., Mallo, D., Paulson, T. G., Li, X., Sanchez, C. A., Reid, B. J., Graham, T. A., Kuhner, M. K., & Maley, C. C. (2018) · Nature Communications · doi:10.1038/s41467-017-02621-x · Cited by 56 · see citing works

Novel staining pattern of p53 in Barrett’s dysplasia – the absent pattern

Kaye, P., Haider, S. A., James, P. D., Soomro, I. N., Catton, J. A., Parsons, S. L., Ragunath, K., & Ilyas, M. (2010) · Histopathology · doi:10.1111/j.1365-2559.2010.03715.x · Cited by 56 · see citing works

Assessment of Esophageal Adenocarcinoma Risk Using Somatic Chromosome Alterations in Longitudinal Samples in Barrett's Esophagus

Li, X., Paulson, T. G., Galipeau, P. C., Sanchez, C. A., Liu, K., Kuhner, M. K., Maley, C. C., Self, S. G., Vaughan, T. L., Reid, B. J., et al. (2015) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-15-0130 · Cited by 53 · see citing works

The evolutionary history of 2,658 cancersPreprint

Gerstung, M., Jolly, C., Leshchiner, I., Dentro, S. C., González, S., Rosebrock, D., Mitchell, T. J., Rubanova, Y., Anur, P., Yu, K., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/161562 · Cited by 51 · see citing works

Clinical Use of p53 in Barrett's Esophagus

Keswani, R. N., Noffsinger, A. E., Waxman, I., & Bissonnette, M. (2006) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-06-0010 · Cited by 46 · see citing works

The incidence of Barrett's oesophagus and oesophageal adenocarcinoma in the United Kingdom and the Netherlands is levelling off

Masclee, G. M. C., Coloma, P. M., de Wilde, M., Kuipers, E. J., & Sturkenboom, M. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12759 · Cited by 46 · see citing works

p53 protein accumulation predicts malignant progression in Barrett's metaplasia: a prospective study of 275 patients

Younes, M., Brown, K., Lauwers, G. Y., Ergun, G. A., Meriano, F. V., Schmulen, A. C., Barroso, A. O., & Ertan, A. (2017) · Histopathology · doi:10.1111/his.13193 · Cited by 33 · see citing works

RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas

Blum, A. E., Venkitachalam, S., Guo, Y. P., Kieber-Emmons, A. M., Ravi, L., Chandar, A. K., Iyer, P. G., Canto, M. I., Wang, J. S., Shaheen, N. J., et al. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-0979 · Cited by 31 · see citing works

β-Catenin Mutations: Insights into the APC Pathway and the Power of Genetics

Morin, P. J., Kinzler, K. W., & Sparks, A. B. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-2387 · Cited by 28 · see citing works

197 A Multicenter, Double-Blinded Validation Study of Methylation Biomarkers for Progression Prediction in Barrett's Esophagus

Jin, Z., Cheng, Y., Gu, J., Zheng, Y., Mori, Y., Olaru, A., Paun, B. C., Kan, T., Hamilton, J. P., Selaru, F. M., et al. (2009) · Gastroenterology · doi:10.1016/s0016-5085(09)60168-2 · Cited by 16 · see citing works

Evaluation of p53 Immunohistochemistry Staining Patterns in Barrett Esophagus With Low-Grade Dysplasia

Pettit, K. A., & Bellizzi, A. M. (2015) · American Journal of Clinical Pathology · doi:10.1093/ajcp/144.suppl2.382 · Cited by 2 · see citing works

Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets

Zhang, S., Xiao, X., Yi, Y., Wang, X., Zhu, L., Shen, Y., Lin, D., & Wu, C. H. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01848-7 · Cited by 440 · see citing works

Genetic and non-genetic clonal diversity in cancer evolution

Black, J. R., & McGranahan, N. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-021-00336-2 · Cited by 287 · see citing works

Advances in diagnosis and management of cancer of the esophagus

Deboever, N., Jones, C. M., Yamashita, K., Ajani, J. A., & Hofstetter, W. L. (2024) · BMJ · doi:10.1136/bmj-2023-074962 · Cited by 258 · see citing works

Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Weusten, B. L. A. M., Bisschops, R., Dinis-Ribeiro, M. J., di Pietro, M., Pech, O., Spaander, M. C. W., Baldaque‐Silva, F., Barret, M., Coron, E., Fernández‐Esparrach, G., et al. (2023) · Endoscopy · doi:10.1055/a-2176-2440 · Cited by 237 · see citing works

Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus

Luebeck, J., Ng, A. W. T., Galipeau, P. C., Li, X., Sanchez, C. A., Katz‐Summercorn, A., Kim, H., Jammula, S., He, Y., Lippman, S. M., et al. (2023) · Nature · doi:10.1038/s41586-023-05937-5 · Cited by 172 · see citing works

Haplotype-aware analysis of somatic copy number variations from single-cell transcriptomes

Gao, T., Soldatov, R., Sarkar, H., Kurkiewicz, A., Biederstedt, E., Loh, P., & Kharchenko, P. V. (2022) · Nature Biotechnology · doi:10.1038/s41587-022-01468-y · Cited by 166 · see citing works

Current status and perspectives of esophageal cancer: a comprehensive review

Jiang, W., Zhang, B., Xu, J., Xue, L., & Wang, L. (2024) · 癌症：英文版 · doi:10.1002/cac2.12645 · Cited by 162 · see citing works

Abnormal TP53 Predicts Risk of Progression in Patients With Barrett’s Esophagus Regardless of a Diagnosis of Dysplasia

Redston, M. S., Noffsinger, A. E., Kim, A., Akarca, F. G., Rara, M. R., Stapleton, D. R., Nowden, L., Lash, R. H., Bass, A. J., & Stachler, M. D. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.10.038 · Cited by 102 · see citing works

Improving outcomes in patients with oesophageal cancer

Shah, M. A., Altorki, N. K., Patel, P., Harrison, S. W., Bass, A. J., & Abrams, J. A. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-023-00757-y · Cited by 101 · see citing works

Evolution and progression of Barrett’s oesophagus to oesophageal cancer

Killcoyne, S., & Fitzgerald, R. C. (2021) · Nature reviews. Cancer · doi:10.1038/s41568-021-00400-x · Cited by 89 · see citing works

Deterministic evolution and stringent selection during preneoplasia

Karlsson, K., Przybilla, M. J., Kotler, E., Khan, A., Xu, H., Karagyozova, K., Sockell, A., Wong, W. H., Liu, K., Mah, A., et al. (2023) · Nature · doi:10.1038/s41586-023-06102-8 · Cited by 83 · see citing works

Immune evasion in HPV − head and neck precancer–cancer transition is driven by an aneuploid switch involving chromosome 9p loss

William, W. N., Zhao, X., Bianchi, J. J., Lin, H. Y., Cheng, P., Lee, J. J., Carter, H. K., Alexandrov, L. B., Abraham, J. P., Spetzler, D. B., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2022655118 · Cited by 82 · see citing works

Use of a Cytosponge biomarker panel to prioritise endoscopic Barrett's oesophagus surveillance: a cross-sectional study followed by a real-world prospective pilot

Pilonis, N., Killcoyne, S., Tan, W. K., O'Donovan, M., Malhotra, S., Tripathi, M., Miremadi, A., Debiram-Beecham, I., Evans, T., Phillips, R., et al. (2022) · The Lancet Oncology · doi:10.1016/s1470-2045(21)00667-7 · Cited by 69 · see citing works

Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis

Ye, B., Fan, D., Xiong, W., Li, M., Yuan, J., Jiang, Q., Zhao, Y., Lin, J., Liu, J., Lv, Y., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24813-2 · Cited by 64 · see citing works

Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers

Chatila, W. K., Walch, H. S., Hechtman, J. F., Moyer, S. M., Sgambati, V., Faleck, D. M., Srivastava, A., Tang, L. H., Benhamida, J. K., Ismailgeci, D., et al. (2023) · Nature Communications · doi:10.1038/s41467-022-35592-9 · Cited by 58 · see citing works

Visceral Obesity, Metabolic Syndrome, and Esophageal Adenocarcinoma

Elliott, J. A., & Reynolds, J. V. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.627270 · Cited by 49 · see citing works

Somatic whole genome dynamics of precancer in Barrett’s esophagus reveals features associated with disease progression

Paulson, T. G., Galipeau, P. C., Oman, K. M., Sanchez, C. A., Kuhner, M. K., Smith, L. P., Hadi, K., Shah, M. J., Arora, K. S., Shelton, J., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-29767-7 · Cited by 46 · see citing works

Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma

Bao, C., Tourdot, R. W., Brunette, G. J., Stewart, C., Sun, L., Baba, H., Watanabe, M., Agoston, A. T., Jajoo, K., Davison, J. M., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41805-6 · Cited by 37 · see citing works

Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma

Strasser, M. K., Gibbs, D. L., Gascard, P. D., Bons, J., Hickey, J. W., Pan, D., Caruso, J. A., Wang, X., Chen‐Tanyolac, C., Bai, R., et al. (2025) · Developmental Cell · doi:10.1016/j.devcel.2025.06.034 · Cited by 36 · see citing works

Multi-omic cross-sectional cohort study of pre-malignant Barrett’s esophagus reveals early structural variation and retrotransposon activity

Katz‐Summercorn, A., Jammula, S., Frangou, A., Peneva, I., O’Donovan, M., Tripathi, M., Malhotra, S., di Pietro, M., Abbas, S., Devonshire, G., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28237-4 · Cited by 36 · see citing works

Adenocarcinoma of the oesophagus: is it gastric cancer?

Quante, M., Wang, T. C., & Bass, A. J. (2022) · Gut · doi:10.1136/gutjnl-2022-327096 · Cited by 35 · see citing works

Decoding the basis of histological variation in human cancer

Fujii, M., Sekine, S., & Sato, T. (2023) · Nature reviews. Cancer · doi:10.1038/s41568-023-00648-5 · Cited by 35 · see citing works

Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals

Vavoulis, D. V., Cutts, A., Thota, N., Brown, J., Sugar, R., Rueda, A., Ardalan, A., Howard, K., Santo, F. M., Sannasiddappa, T., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55428-y · Cited by 35 · see citing works

Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett’s Esophagus

Douville, C. B., Moinova, H., Thota, P. N., Shaheen, N. J., Iyer, P. G., Canto, M. I., Wang, J. S., Dumot, J. A., Faulx, A. L., Kinzler, K. W., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.01.209 · Cited by 33 · see citing works

Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer

Fernández-Mateos, J., Cresswell, G. D., Trahearn, N., Webb, K., Sakr, C., Lampis, A., Stuttle, C., Corbishley, C. M., Stavrinides, V., Zapata, L., et al. (2024) · Nature Cancer · doi:10.1038/s43018-024-00787-0 · Cited by 31 · see citing works

Data-driven decision-making for precision diagnosis of digestive diseases

Jiang, S., Wang, T., & Zhang, K.-H. (2023) · BioMedical Engineering OnLine · doi:10.1186/s12938-023-01148-1 · Cited by 29 · see citing works

Relationship between clonal evolution and drug resistance in bladder cancer: A genomic research review

Tuo, Z., Zhang, Y., Li, D., Wang, Y., Wu, R., Wang, J., Yu, Q., Ye, L., Shao, F., Wusiman, D., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107302 · Cited by 27 · see citing works

Circulating Tumor DNA-Based Disease Monitoring of Patients with Locally Advanced Esophageal Cancer

Hofste, L. S. M., Geerlings, M. J., von Rhein, D. T., Tolmeijer, S. H., Weiss, M. M., Gilissen, C., Hofste, T. G. J., Garms, L. M., Janssen, M. J. R., Rütten, H., et al. (2022) · Cancers · doi:10.3390/cancers14184417 · Cited by 27 · see citing works

Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer

Ganguli, P., Basanta, C. D. L. A. C., Acha‐Sagredo, A., Mišetić, H., Armero, M., Mendez, A., Zahra, A., Devonshire, G., Kelly, G. P., Freeman, A., et al. (2025) · Nature Cancer · doi:10.1038/s43018-024-00876-0 · Cited by 26 · see citing works

Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies

Rane, J. K., Frankell, A. M., Weeden, C. E., & Swanton, C. (2023) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-22-0469 · Cited by 26 · see citing works

Biomarker risk stratification with capsule sponge in the surveillance of Barrett's oesophagus: prospective evaluation of UK real-world implementation

Tan, W. K., Ross-Innes, C. S., Somerset, T., Markert, G., Markowetz, F. M., O’Donovan, M., di Pietro, M., Sasieni, P. D., Fitzgerald, R. C., Askinyte, V., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01021-9 · Cited by 24 · see citing works

Surveillance in Barrett’s Esophagus: Challenges, Progress, and Possibilities

Iyer, P. G., & Chak, A. (2023) · Gastroenterology · doi:10.1053/j.gastro.2023.01.031 · Cited by 22 · see citing works

Improvement in the risk assessment of oral leukoplakia through morphology-related copy number analysis

Li, X., Liu, L., Zhang, J., Ma, M., Sun, L., Li, X., Zhang, H., Wang, J., Huang, Y., & Li, T. (2021) · Science China Life Sciences · doi:10.1007/s11427-021-1965-x · Cited by 20 · see citing works

Barrett's esophagus: The pathomorphological and molecular genetic keystones of neoplastic progression

Maslenkina, K. S., Konyukova, A. K., Alexeeva, D. Y., Sinelnikov, M. Y., & Михалева, Л. М. (2021) · Cancer Medicine · doi:10.1002/cam4.4447 · Cited by 20 · see citing works

A View on Drug Development for Cancer Prevention

Reynolds, A. R., Moschetta, M., Yohannes, A. R., Walcott, F. L., Ashford, M. B., Szűcs, Z., Sarbajna, T., Hadfield, J., Harrison, E., Challis, B., et al. (2023) · Cancer Discovery · doi:10.1158/2159-8290.cd-22-0776 · Cited by 19 · see citing works

Genomics define malignant transformation in myeloma precursor conditions

Maura, F., Bergsagel, P. L., Ziccheddu, B., Kumar, S., Maclachlan, K., Derkach, A., Garces, J.-J., Firestone, R., Braggio, E., Asmann, Y., et al. (2026) · Journal of Clinical Oncology · doi:10.1200/jco-25-01733 · Cited by 18 · see citing works

Copy Number Alterations Predict Development of OSCC from Oral Leukoplakia

Cai, X., Zhang, J., Li, L., Liu, L., Tang, M., Zhou, S., Peng, C.-R., Li, X., Chen, X., Xu, M., et al. (2024) · Journal of Dental Research · doi:10.1177/00220345231217160 · Cited by 18 · see citing works

The risk of neoplasia in patients with Barrett's esophagus indefinite for dysplasia: a multicenter cohort study

Phillips, R., Januszewicz, W., Pilonis, N., O’Donovan, M., Sawas, T., Katzka, D. A., Fitzgerald, R. C., & di Pietro, M. (2021) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2021.01.042 · Cited by 18 · see citing works

Genomic instability signals offer diagnostic possibility in early cancer detection

Killcoyne, S., Yusuf, A., & Fitzgerald, R. C. (2021) · Trends in Genetics · doi:10.1016/j.tig.2021.06.009 · Cited by 18 · see citing works

Esophageal Squamous Cancer from 4NQO-Induced Mice Model: CNV Alterations

Liu, Z., Su, R., Su, R., Liu, C., Liao, X., Tian, D., & Su, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232214304 · Cited by 18 · see citing works

Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis

Bakir, I. A., Curtius, K., Cresswell, G. D., Grant, H. E., Nasreddin, N., Smith, K., Nowinski, S., Guo, Q., Belnoue-Davis, H. L., Fisher, J., et al. (2025) · Gut · doi:10.1136/gutjnl-2024-333353 · Cited by 17 · see citing works

Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era

Barchi, A., Dell’Anna, G., Massimino, L., Mandarino, F. V., Vespa, E., Viale, E., Passaretti, S. M., Annese, V., Malesci, A., Danese, S., et al. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2024.1458138 · Cited by 17 · see citing works

Evolutionary dynamics in Barrett oesophagus: implications for surveillance, risk stratification and therapy

Schmidt, M., HACKETT, R. J., Baker, A., McDonald, S. A. C., Quante, M., & Graham, T. A. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00531-4 · Cited by 17 · see citing works

Absolute copy number fitting from shallow whole genome sequencing dataPreprint

Sauer, C. M., Eldridge, M., Vias, M., Hall, J. A. M., Boyle, S. E., Macintyre, G., Bradley, T. P., Markowetz, F. M., & Brenton, J. D. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.19.452658 · Cited by 17 · see citing works

Comprehensive Analysis of Genomic Alterations in Hepatoid Adenocarcinoma of the Stomach and Identification of Clinically Actionable Alterations

Zhao, R., Li, H., Ge, W., Zhu, X., Zhu, L., Wan, X., Wang, G., Pan, H., Lu, J., & Han, W. (2022) · Cancers · doi:10.3390/cancers14163849 · Cited by 16 · see citing works

Clonal cell states link gastroesophageal junction tissues with metaplasia and cancer

Gier, R. A., Bracht, S. A., Rong, J., Hueros, R. A. R., Wahlsten, M., Cote, C. J., DeMarshall, M., Karakasheva, T. A., Strauss, A. L., Muir, A. B., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66302-w · Cited by 16 · see citing works

Genomic and Transcriptomic Characteristics of Esophageal Adenocarcinoma

Hoppe, S., Jonas, C., Wenzel, M. C., Camacho, O. V., Arolt, C., Zhao, Y., Büttner, R., Quaas, A., Plum, P. S., & Hillmer, A. M. (2021) · Cancers · doi:10.3390/cancers13174300 · Cited by 15 · see citing works

Precision diagnostics: integration of tissue pathology and genomics in cancer

Sharma, S., George, P. M., & Waddell, N. (2021) · Pathology · doi:10.1016/j.pathol.2021.08.003 · Cited by 15 · see citing works

Accurate integration of single-cell DNA and RNA for analyzing intratumor heterogeneity using MaCroDNA

Edrisi, M., Huang, X., Ogilvie, H. A., & Nakhleh, L. K. (2023) · Nature Communications · doi:10.1038/s41467-023-44014-3 · Cited by 15 · see citing works

The ALT pathway generates telomere fusions that can be detected in the blood of cancer patients

Muyas, F., Gómez, M. J., Cascão, R., Afonso, Â., Sauer, C. M., Faria, C. C., Cortés‐Ciriano, I., & Flores, I. (2024) · Nature Communications · doi:10.1038/s41467-023-44287-8 · Cited by 14 · see citing works

Transgelin Inhibits the Malignant Progression of Esophageal Squamous Cell Carcinomas by Regulating Epithelial–Mesenchymal Transition

Yang, B., Chen, Q., Wan, C., Sun, S., Zhu, L., Zhao, Z., Zhong, W., & Wang, B. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.709486 · Cited by 14 · see citing works

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

Zhang, N., Harbers, L., Simonetti, M., Diekmann, C., Verron, Q., Berrino, E., Bellomo, S. E., Longo, G. M. C., Ratz, M., Schultz, N., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47664-z · Cited by 12 · see citing works

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS–chemokine–myeloid axis

Beernaert, B., Jady‐Clark, R. L., Shah, P., Ramon‐Gil, E., Lawson, N. M., Brodtman, Z. D., Tagore, S., Stihler, F., Carter, A., Clarke, S., et al. (2026) · Science Advances · doi:10.1126/sciadv.aeb1611 · Cited by 11 · see citing works

Loss of Y chromosome: An emerging next-generation biomarker for disease prediction and early detection?

Guo, X., Li, J., Xue, J., Fenech, M. F., & Wang, X. (2021) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2021.108389 · Cited by 11 · see citing works

Challenges in Determining the Role of Microbiome Evolution in Barrett’s Esophagus and Progression to Esophageal Adenocarcinoma

Guccione, C., Yadlapati, R. H., Shah, S. C., Knight, R. D., & Curtius, K. (2021) · Microorganisms · doi:10.3390/microorganisms9102003 · Cited by 11 · see citing works

Genetic Pathogenesis of Inflammation-Associated Cancers in Digestive Organs

Nakanishi, R., Shimizu, T., Kumagai, K., Takai, A., & Marusawa, H. (2021) · Pathogens · doi:10.3390/pathogens10040453 · Cited by 11 · see citing works

HPGD induces ferroptosis and autophagy to suppress esophageal squamous cell carcinoma through the LXA4–ERK1/2–U2AF2–TFRC axis

Ma, T., Guo, X., Zhao, J., Wang, C., Yu, X., Mo, R., Han, Z., Feng, L., Liu, L., Yu, W., et al. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02464-x · Cited by 10 · see citing works

Dedicated service for Barrett’s oesophagus surveillance endoscopy yields higher dysplasia detection and guideline adherence in a non-tertiary setting in the UK: a 5-year comparative cohort study

Ratcliffe, E. G., Britton, J., Yalamanchili, H., Rostami, I., Nadir, S. M. H., Korani, M., Eruchie, I., Wazirdin, M. A., Prasad, N., Hamdy, S., et al. (2023) · Frontline Gastroenterology · doi:10.1136/flgastro-2023-102425 · Cited by 10 · see citing works

Stimuli-responsive incremental DNA machine auto-catalyzed CRISPR-Cas12a feedback amplification permits ultrasensitive molecular diagnosis of esophageal cancer-related microRNA

Li, H., Wang, Y., Wan, Y., Li, M., Xu, J., Wang, Q., & Wu, D. (2024) · Talanta · doi:10.1016/j.talanta.2024.125675 · Cited by 10 · see citing works

The path(ology) from reflux oesophagitis to Barrett oesophagus to oesophageal adenocarcinoma

Salimian, K. J., Birkness-Gartman, J. E., & Waters, K. M. (2021) · Pathology · doi:10.1016/j.pathol.2021.08.006 · Cited by 10 · see citing works

Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice

Tian, Y., Zhou, J., Qiao, J., Liu, Z., Gu, L., Zhang, B., Lu, Y., Xing, R., & Deng, D. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1038380 · Cited by 9 · see citing works

Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data

Lu, B. (2024) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2024.04.003 · Cited by 9 · see citing works

Evolution of Multiple Myeloma from a Genomic Perspective

Maura, F., Samur, M., & Munshi, N. (2026) · Blood · doi:10.1182/blood.2024026313 · Cited by 8 · see citing works

Novel devices and biomarkers in screening for esophageal squamous cell cancer

Januszewicz, W., & Nowicki-Osuch, K. (2025) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2025.102005 · Cited by 8 · see citing works

Engineering and biofabrication of early cancer models

Helms, H. R., Davies, A. E., Schutt, C. E., Langer, E. M., Duhen, R., Sinawang, P. D., Akin, D., Demirci, U., Esener, S. C., Fitzgerald, R. C., et al. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00371-w · Cited by 7 · see citing works

CNETML: maximum likelihood inference of phylogeny from copy number profiles of multiple samples

Lu, B., Curtius, K., Graham, T. A., Yang, Z., & Barnes, C. P. (2023) · Genome biology · doi:10.1186/s13059-023-02983-0 · Cited by 7 · see citing works

Advances in colorectal cancer genomics and transcriptomics drive early detection and prevention

Lam, K. K., Thean, L. F., & Cheah, P. Y. (2021) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2021.106032 · Cited by 7 · see citing works

Ethical and legal implications of implementing risk algorithms for early detection and screening for oesophageal cancer, now and in the future

Brigden, T., Mitchell, C., Hill, E. R., & Hall, A. (2023) · PLoS ONE · doi:10.1371/journal.pone.0293576 · Cited by 7 · see citing works

Integrated epidemiological and molecular data inform the relationship between precancer and cancer states of esophageal adenocarcinoma

Zamani, S. A., Wu, L., Black, E. L., Bartram, A., Ng, A. W. T., Secrier, M., Perelman, J. D., Ustaoglu, A., Ococks, E., Jacobson, D. H., et al. (2026) · Nature Medicine · doi:10.1038/s41591-026-04331-8 · Cited by 6 · see citing works

Degree of crypt atypia correlates with progression to high‐grade dysplasia/adenocarcinoma in non‐dysplastic Barrett's oesophagus

Odze, R. D., Frei, N. F., Khoshiwal, A. M., Duits, L. C., Bergman, J. J. G. H. M., & Stachler, M. D. (2023) · Histopathology · doi:10.1111/his.14959 · Cited by 6 · see citing works

Lessons learned from the BOSS trial: new directions in Barrett's oesophagus

Fitzgerald, R. C., & Sasieni, P. D. (2025) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(25)00160-8 · Cited by 6 · see citing works

Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury

Chen, T., Zeineldin, M., Johnson, B. A., Dong, Y., Narkar, A., Li, T., Zhu, J., Li, R., & Larman, T. (2021) · Neoplasia · doi:10.1016/j.neo.2021.03.010 · Cited by 6 · see citing works

Clinical significance of chromosomal integrity in gastric cancers

Zhang, R., Liu, Z., Chang, X., Gao, Y., Han, H., Liu, X., Cai, H., Fu, Q., Liu, L., & Yin, K. (2022) · The International Journal of Biological Markers · doi:10.1177/03936155221106217 · Cited by 6 · see citing works

The Involvement of Oral Pathogenic Bacteria, Fusobacterium nucleatum Subspecies animalis in the Pathogenesis of Human Esophageal Adenocarcinoma

Kitano, T., Okumura, S., Matsumoto, T., Tsunoda, S., Nishigori, T., Obama, K., & Hara, E. (2025) · Gastro Hep Advances · doi:10.1016/j.gastha.2025.100660 · Cited by 5 · see citing works

Today’s Mistakes and Tomorrow’s Wisdom in Development and Use of Biomarkers for Barrett’s Esophagus

Frei, N. F., & Stachler, M. D. (2022) · Visceral Medicine · doi:10.1159/000521706 · Cited by 5 · see citing works

Barrett’s oesophagus with indefinite for dysplasia shows high rates of prevalent and incident neoplasia in a UK multicentre cohort

Kopczynska, M., Ratcliffe, E. G., Yalamanchili, H., Thompson, A., Nimri, A., Britton, J., & Ang, Y. S. (2022) · Journal of Clinical Pathology · doi:10.1136/jcp-2022-208524 · Cited by 5 · see citing works

Early Diagnostic Markers for Esophageal Squamous Cell Carcinoma: Copy Number Alteration Gene Identification and cfDNA Detection

Chen, J., Liu, X., Zhang, Z., Su, R., Geng, Y., Guo, Y., Zhang, Y., & Su, M. (2024) · Laboratory Investigation · doi:10.1016/j.labinv.2024.102127 · Cited by 5 · see citing works

Somatic copy number alterations are predictive of progression-free survival in patients with lung adenocarcinoma undergoing radiotherapy

Kou, F., Wu, L., Guo, Y. H., Zhang, B., Li, B., Huang, Z., Ren, X., & Yang, L. (2021) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2020.0728 · Cited by 5 · see citing works

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohortsPreprint

Strand, S. H., Rivero‐Gutiérrez, B., Houlahan, K. E., Seoane, J. A., King, L. M., Risom, T., Simpson, L., Vennam, S., Khan, A., Cisneros, L. H., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.16.448585 · Cited by 5 · see citing works

Monitoring Hepatocellular Carcinoma Using Tumor Content in Circulating Cell-Free DNA

Lian, S., Lu, C., Li, F., Yu, X., Ai, L., Wu, B., Gong, X., Zhou, W., Liang, X., Zhan, J., et al. (2024) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-23-3449 · Cited by 4 · see citing works

The biology and therapeutic implications of heterogeneity in Barrett oesophagus and oesophageal adenocarcinoma

McClurg, D. P., Pan, S., Fitzgerald, R. C., & Jones, C. M. (2025) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-025-01084-0 · Cited by 4 · see citing works

Developing patient-orientated Barrett’s oesophagus services: the role of dedicated services

Ratcliffe, E. G., Britton, J., Hamdy, S., McLaughlin, J. T., & Ang, Y. S. (2022) · BMJ Open Gastroenterology · doi:10.1136/bmjgast-2021-000829 · Cited by 4 · see citing works

Alterations of the composition and spatial organization of the microenvironment following non-dysplastic Barrett’s esophagus through progression to cancerPreprint

Lin, M., Hickey, J. W., Passman, A. M., Carlotti, E., Devkumar, S., Derwa, Y. H., Chin‐Aleong, J., HACKETT, R. J., Evans, J. C., Sangwan, V., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.09.657642 · Cited by 4 · see citing works

Harnessing genomics for early cancer detection, risk stratification and prevention

Gu, M., Zhang, W. Z., Fitzgerald, R. C., Frankell, A. M., & Vassiliou, G. S. (2026) · Nature Genetics · doi:10.1038/s41588-026-02505-1 · Cited by 3 · see citing works

Characterization of the evolution trajectory and immune profiling of new histologic patterns in lung adenocarcinoma

Song, M., Xie, H., Liu, W., Zhao, M., Deng, Z., Zhang, L., Liu, H., Huang, Y., Li, H., Ren, Y., et al. (2022) · The Journal of Gene Medicine · doi:10.1002/jgm.3455 · Cited by 3 · see citing works

Definition of a Multi-Omics Signature for Esophageal Adenocarcinoma Prognosis Prediction

Lambroia, L., Dioguardi, C. C., Puccio, S., Pansa, A., Alvisi, G., Basso, G., Cibella, J., Colombo, F., Marano, S., Basato, S., et al. (2024) · Cancers · doi:10.3390/cancers16152748 · Cited by 3 · see citing works

Transcriptomic changes and gene fusions during the progression from Barrett’s esophagus to esophageal adenocarcinoma

Fu, Y., Agrawal, S., Snyder, D. R., Yin, S., Zhong, N., Grunkemeyer, J. A., Dietz, N., Corlett, R., Hansen, L. A., Al‐Refaie, W. B., et al. (2024) · Biomarker Research · doi:10.1186/s40364-024-00623-8 · Cited by 3 · see citing works

42 ABNORMAL TP53 PREDICTS RISK OF PROGRESSION IN PATIENTS WITH BARRETT'S ESOPHAGUS REGARDLESS OF A DIAGNOSIS OF DYSPLASIA

Redston, M. S., Noffsinger, A. E., Stapleton, D. R., Stapleton, L., Lash, R. H., Bass, A. J., & Stachler, M. D. (2021) · Gastroenterology · doi:10.1016/s0016-5085(21)00779-4 · Cited by 3 · see citing works

Histological evaluation of PAXgene tissue fixation in Barrett’s esophagus and esophageal adenocarcinoma diagnostics

Barroux, M., Horstmann, J., Fricke, L., Schömig, L. R., Werner, M., Kraynova, E., Kamarádová, K., Fléjou, J., Maerkel, B., Kumarasinghe, P. M., et al. (2022) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-022-03471-9 · Cited by 3 · see citing works

The etiology of clonal mosaicism in human aging and disease

Massaar, S., & Sanders, M. A. (2023) · Aging and Cancer · doi:10.1002/aac2.12061 · Cited by 3 · see citing works

Single-cell Genomic Copy Number Evolution Reveals Frequent Loss of the Y chromosome in Esophageal AdenocarcinomaPreprint

Yin, S., Zhong, N., Agrawal, S., Feng, B., Pradhan, S., Jobalia, N. K., Vaziripour, M., Poreddy, S., Kresty, L. A., Gillaspie, E. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.14.676175 · Cited by 3 · see citing works

Integrative Multiomic Classification Reveals Distinct Origins and Evolutionary Trajectories of Thymic Epithelial Tumors

Park, S., Yi, K., Lee, J. L., Yang, M. J., Song, J.-H., Lim, J., Kim, T., Kim, S., Kim, S. M. (., Kim, H. S., et al. (2026) · Cancer Research · doi:10.1158/0008-5472.can-24-4977 · Cited by 2 · see citing works

Prediction of neoplastic progression in Barrett’s esophagus using nanoscale nuclear architecture mapping: a pilot study

Thota, P. N., Nasibli, J., Kumar, P. N., Sanaka, M. R., Chak, A., Zhang, X., Liu, X., Uttam, S., & Liu, Y. (2022) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2022.01.007 · Cited by 2 · see citing works

Secondary prevention of gastric cancer and Traditional Chinese Medicine countermeasures

Tang, X., Liu, L., Wang, F., & Wang, P. (2022) · Scientia Sinica Vitae · doi:10.1360/ssv-2021-0396 · Cited by 2 · see citing works

P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy

Qiu, Q., Guo, G., Guo, X., Hu, X., Yu, T., Liu, G., Zhang, H., Chen, Y., & She, J. (2023) · Biomedicines · doi:10.3390/biomedicines11030882 · Cited by 2 · see citing works

Solving problems is smart, preventing them is wise: Lessons learned from the 2nd International DKFZ Conference on Cancer Prevention

Gillmann, C., Pajor, G., Ramadori, P., Albers, P., Mons, U., Steindorf, K., Kentner, S., & Baumann, M. A. (2021) · International Journal of Cancer · doi:10.1002/ijc.33502 · Cited by 2 · see citing works

The future of therapy of Barrett’s esophagus and related cancer: a narrative review

Pilonis, N., & di Pietro, M. (2021) · Annals of Esophagus · doi:10.21037/aoe-20-93 · Cited by 1 · see citing works

Diagnostic and Prognostic Biomarkers for Barrett’s Esophagus

Wang, F., Kahn, A., Kisiel, J. B., & Iyer, P. G. (2025) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2025.09.001 · Cited by 1 · see citing works

Dissecting oral premalignant carcinogenesis: spatial omics mechanisms and nanomedicine-driven therapeutic innovation

Cai, X., Cui, Y. R., Ding, C., Liu, Y., & Li, T. Y. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02727-1 · Cited by 1 · see citing works

Identification and Analysis of Sex-Biased Copy Number Alterations

Zhang, C., Yang, Y., Cui, Q., Zhao, D., & Cui, C. (2024) · Health Data Science · doi:10.34133/hds.0121 · Cited by 1 · see citing works

A genomic instability-based model for Barrett’s oesophagus progression

Romero, D. (2020) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-00436-2

Genomic Test Predicts Malignant Transformation of Barrett's Esophagus

(2020) · Cancer Discovery · doi:10.1158/2159-8290.cd-rw2020-134

Practical early cancer detection: distinguishing stable from unstable genomes in pre-cancerous tissues

Killcoyne, S., & Fitzgerald, R. C. (2020) · British Journal of Cancer · doi:10.1038/s41416-020-01142-7 · Cited by 1 · see citing works

Can Genomic Sequencing Identify High-Risk Barrett’s Esophagus Earlier Than Pathologists?

Stachler, M. D., & Bass, A. J. (2020) · Cancer Cell · doi:10.1016/j.ccell.2020.10.020 · Cited by 1 · see citing works

Whole genome analysis of copy number changes in Barrett's esophagus and esophageal adenocarcinoma.

Paulson, T. G., Maley, C. C., Li, X., Zhang, G., Li, H., Odze, R. D., Blount, P. L., & Reid, B. J. (2006) · Cancer Epidemiology and Prevention Biomarkers