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Cited by 373

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Post-Colonoscopy Complications: A Systematic Review, Time Trends, and Meta-Analysis of Population-Based Studies

Reumkens, Ankie, Rondagh, Eveline J A, Bakker, Minke C, Winkens, Bjorn, Masclee, Ad A M, Sanduleanu, Silvia·2016·American Journal of Gastroenterology

Abstract

OBJECTIVES: Many studies around the world addressed the post-colonoscopy complications, but their pooled prevalence and time trends are unknown. We performed a systematic review and meta-analysis of population-based studies to examine the pooled prevalence of post-colonoscopy complications ("perforation", "bleeding", and "mortality"), stratified by colonoscopy indication. Temporal variability in the complication rate was assessed. METHODS: We queried Pubmed, Embase, and the Cochrane library for population-based studies examining post-colonoscopy complications (within 30 days), performed from 2001 to 2015 and published by 1 December 2015. We determined pooled prevalence of perforations, post-colonoscopy bleeding, post-polypectomy bleeding, and mortality. RESULTS: We retrieved 1,074 studies, of which 21 met the inclusion criteria. Overall, pooled prevalences for perforation, post-colonoscopy bleeding, and mortality were 0.5/1,000 (95% confidence interval (CI) 0.4-0.7), 2.6/1,000 (95% CI 1.7-3.7), and 2.9/100,000 (95% CI 1.1-5.5) colonoscopies. Colonoscopy with polypectomy was associated with a perforation rate of 0.8/1,000 (95% CI 0.6-1.0) and a post-polypectomy bleeding rate of 9.8/1,000 (95% CI 7.7-12.1). Complication rate was lower for screening/surveillance than for diagnostic examinations. Time-trend analysis showed that post-colonoscopy bleeding declined from 6.4 to 1.0/1,000 colonoscopies, whereas the perforation and mortality rates remained stable from 2001 to 2015. Overall, considerable heterogeneity was observed in most of the analyses. CONCLUSIONS: Worldwide, the post-colonoscopy complication rate remained stable or even declined over the past 15 years. The findings of this meta-analysis encourage continued efforts to achieve and maintain safety targets in colonoscopy practice.

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Metadata

Authors
Reumkens, A., Rondagh, E. J. A., Bakker, M. C., Winkens, B., Masclee, A. A. M., & Sanduleanu, S.
Venue
American Journal of Gastroenterology
Published
2016-08
Volume
111
Issue
8
Pages
1092-1101
ISSN
0002-9270 (ISSN-L)
OpenAlex
W2427807572
Cited by
373
References
39
FWCI
4.17
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Post-Colonoscopy Complications: A Systematic Review, Time Trends, and Meta-Analysis of Population-Based Studies. https://app.cochat.ai/papers/10.1038/ajg.2016.234
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Reumkens, A., Rondagh, E. J. A., Bakker, M. C., Winkens, B., Masclee, A. A. M., & Sanduleanu, S. (2016). Post-Colonoscopy Complications: A Systematic Review, Time Trends, and Meta-Analysis of Population-Based Studies. American Journal of Gastroenterology. https://doi.org/10.1038/ajg.2016.234

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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