The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.
Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system
Open accessAbstract
It has been widely recognized that inflammation, particularly chronic inflammation, can increase the risk of cancer and that the simultaneous treatment of inflammation and cancer may produce excellent therapeutic effects. Berberine, an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic with a long history. Over the past decade, many reports have demonstrated that this natural product and its derivatives have high activity against both cancer and inflammation. In this review, we summarize the advances in studing berberine and its derivatives as anti-inflammatory and anti-tumor agents in the digestive system; we also discuss their structure-activity relationship. These data should be useful for the development of this natural product as novel anticancer drugs with anti-inflammation activity.
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Cites
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Cited by
Effects of Berberine and Its Derivatives on Cancer: A Systems Pharmacology Review
Zhang, C., Sheng, J., Li, G., Zhao, L., Wang, Y., Yang, W., Yao, X., Sun, L., Zhang, Z., & Cui, R. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01461 · Cited by 102
The mechanism of berberine alleviating metabolic disorder based on gut microbiome
Wang, H., Zhang, H., Gao, Z., Zhang, Q., & Gu, C. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.854885 · Cited by 69
Self-citationDehau, T., Cherlet, M., Croubels, S., Van De Vliet, M., Goossens, E., & Van Immerseel, F. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1281090 · Cited by 33
Haller, O. J., Semendric, I., George, R. P., Collins-Praino, L. E., & Whittaker, A. L. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105120 · Cited by 13
Metadata
- Authors
- Zou, K., Li, Z., Zhang, Y., Zhang, H.-Y., Li, B., Zhu, W.-L., Shi, J.-Y., Jia, Q., & Li, Y.-M.
- Venue
- Acta Pharmacologica Sinica
- Published
- 2016-12-05
- Volume
- 38
- Issue
- 2
- Pages
- 157-167
- ISSN
- 0253-9756 (ISSN-L)
- 1671-4083
- 1745-7254
- OpenAlex
- W2560593836
- Cited by
- 317
- References
- 75
- FWCI
- 13.84
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zou, K., Li, Z., Zhang, Y., Zhang, H.-Y., Li, B., Zhu, W.-L., Shi, J.-Y., Jia, Q., & Li, Y.-M. (2017). Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system. Acta Pharmacologica Sinica. https://doi.org/10.1038/aps.2016.125
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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