Cited by 89Cancer survivorship and careSleep and related disordersCircadian rhythm and melatonin

Effect of walking on circadian rhythms and sleep quality of patients with lung cancer: a randomised controlled trial

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Chen, Hui-Mei, Tsai, Chun-Ming, Wu, Yu-Chung, Lin, Kuan-Chia, Lin, Chia-Chin·2016·British Journal of Cancer

Abstract

BACKGROUND: Sleep disturbances and poor rest-activity rhythms, which can reduce the quality of life, are highly prevalent among patients with lung cancer. METHODS: This trial investigated the effects of a 12-week exercise intervention including home-based walking exercise training and weekly exercise counseling on 111 lung cancer patients. Participants were randomly allocated to receive the intervention or usual-care. Outcomes included objective sleep (total sleep time, TST; sleep efficiency, SE; sleep onset latency, SOL; and wake after sleep onset, WASO), subjective sleep (Pittsburgh Sleep Quality Index, PSQI), and rest-activity rhythms (r24 and I<O). Outcomes were assessed at baseline and 3 and 6 months after intervention. RESULTS: =7.59, P=0.023) of the patients in the exercise group significantly improved 3 and 6 months after intervention. The moderating effect of I<O on TST was significant (β of group × I

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Authors
Chen, H.-M., Tsai, C.-M., Wu, Y.-C., Lin, K.-C., & Lin, C.-C.
Affiliations
  • National Taipei University of Nursing and Health Science (TW)
  • Taipei Veterans General Hospital (TW)
  • National Yang Ming University (TW)
  • Taipei Medical University (TW)
Corresponding author
  • Lin, Kuan-Chia
  • Lin, Chia-Chin
Venue
British Journal of Cancer
Published
2016-11
Volume
115
Issue
11
Pages
1304-1312
ISSN
  • 0007-0920 (ISSN-L)
  • 1532-1827
OpenAlex
W2548369948
Cited by
89
References
38
Citations by year
2026: 8 · 2025: 8 · 2024: 10 · 2023: 14 · 2022: 12 · 2021: 7 · 2020: 7 · 2019: 9 · 2018: 10 · 2017: 3
FWCI
3.95
Type
journal article
Language
en
Open access
Locations
  • British Journal of Cancer (publishedVersion, cc-by-nc-sa)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
  • The HKU Scholars Hub (University of Hong Kong) (submittedVersion, cc-by-nc-nd)
Funders
National Science Council
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Keywords
lung cancer, walking exercise, home-based exercise training, sleep quality, circadian rhythm, rest-activity rhythm, sleep disorders, total sleep time, sleep efficiency, sleep latency, wake after sleep onset, physical activity counseling, quality of life
MeSH terms
Adult, Aged, Aged, 80 and over, Circadian Rhythm, Female, Humans, Lung Neoplasms, Male, Middle Aged, Quality of Life, Sleep, Walking

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