TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

Jouan-Lanhouet, S, Arshad, M I, Piquet-Pellorce, C, Martin-Chouly, C, Le Moigne-Muller, G, Van Herreweghe, F, Takahashi, N, Sergent, O +4 more·2012·Cell Death & Differentiation

Cited by (362)

Items 301–362 of 362

  1. AATF Competitively Interacts with Nuclear AIF and Inhibits Parthanatos of Neurons in dMCAO/R and OGD/R Models
    Wei Xu, Zhen Hu, Dou Yin, Yue Zeng, Xiaoxiao Zhang, Wei Jin, Chuancheng Ren · 2022 · Journal of Molecular Neuroscience
  2. Necroptosis
    Ben A. Croker, James A. Rickard, Inbar Shlomovitz, Arshed Al‐Obeidi, Akshay A. D’Cruz, Motti Gerlic · 2018 · Wiley eBooks
  3. Small-molecule modulators of the necroptotic pathway: A medicinal chemistry perspective
    De-Chang Li, Nannan Chen, Qi-Dong You, Xiaoli Xu · 2026 · European Journal of Medicinal Chemistry
  4. Necroptosis, a Potential Therapeutic Target for Neurological Disorders
    Jing Chen, Richard M. Kostrzewa, Xingshun Xu · 2014 · Springer eBooks
  5. Seminars in Cell & Developmental Biology
    Wen Zhou, Junying Yuan · 2014
  6. Programmed cell death and liver diseases
    Н. А. Онищенко, З. З. Гоникова, Alla O. Nikolskaya, Л. А. Кирсанова, V. I. Sevastianov · 2022 · Russian Journal of Transplantology and Artificial Organs
  7. RIPK3-dependent sequential recruitment of MLKL and RIPK1 drives PANoptotic cell death and chemokine production
    Yu Yang, Yue Wang, Yang Wang, Erpeng Wu, Hao Chen, Liming Sun, Chi Zhang, Shuhui Cao, JINGWEN LI, Huiping Qiang et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Regulation of Necroptosis by Aspergillus fumigatus Exopolysaccharide in Human Macrophages Derived from THP-1 Cells: Involvement of the RIP1-RIP3-MLKL Signaling Axis
    Wei Shen, Meng Wang, Ting Han, Yan Yao, Xinyi Ying, Yuyue Cui, Peng Du · 2025 · Current Microbiology
  9. Discovery of benzothiazole derivatives as novel orally receptor-interacting protein kinase 1 (RIPK1) inhibitors for inflammatory disease therapy
    Chufeng Zhang, Yulian Chen, Minghai Tang, Shunjie Zhang, Wei Yan, Yong Li, Na Li, Haoyu Zhao, Mingrui Li, Ziyan Ma et al. · 2025 · European Journal of Medicinal Chemistry
  10. Cyclopropyl as a versatile tool in the development of kinase-targeted therapeutics
    Wenwu Liu, Yaoguang Huang, Wenyan Hao, Zhuona Rong, Xinhua Liu, Ying Zhou, Song Song, Xiaocong Pang · 2026 · European Journal of Medicinal Chemistry
  11. Le criblage à Roscoff
    Blandine Baratte, Benoît Serive, Stéphane Bach · 2015 · médecine/sciences
  12. Small-Molecule Inhibitors of Necroptosis
    Colleen R. McNamara, Alexei Degterev · 2014 · Springer eBooks
  13. NOX1, Reactive Oxygen Species, JNK, and Necrotic Cell Death
    Michael J. Morgan, You‐Sun Kim · 2014 · Springer eBooks
  14. Mechanisms of Cell Death in the Developing Brain
    Claire Thornton, Henrik Hagberg · 2016 · Elsevier eBooks
  15. Cell Death and Autoimmune Disease
    Stefania Gallucci, Roberto Caricchio, Philip L. Cohen · 2019 · Elsevier eBooks
  16. Endogenous Soluble TRAIL Contributes to the Survival and Growth of Human Mesenchymal Stem Cells
    Joaquín Marco-Brualla, Ana Gallego-Lleyda, Sanz Jara, Desportes Paula, Fernandez Hernandez Pablo, Luis Martínez‐Lostao, Lapuente Pedro, Alberto Anel · 2021 · International Journal of Stem cell Research & Therapy
  17. Targeting Necroptosis as Therapeutic Potential in Central Nervous System Diseases
    Hao Li, Meiling Xia, Jing Chen, Richard M. Kostrzewa, Xingshun Xu · 2022 · Springer eBooks
  18. Roles in innate immune receptors: Host : pathogen interactions and strengthening vaccines
    Sanna Nyström · 2013 · Figshare
  19. Cellular Injury and Apoptosis
    Stefania Gallucci, Roberto Caricchio, Philip L. Cohen · 2013 · Elsevier eBooks
  20. Necrostatin-1: Its Discovery and Application in Cell Death Research
    Dana E. Christofferson, Ying Li, Junying Yuan · 2014 · Springer eBooks
  21. The Paradoxical Roles of Cell Death Pathways in Immune Cells
    Scott McComb · 2013 · uO Research (University of Ottawa)
  22. Other Determinants of Sensitivity
    Naoyuki Okita, Atsushi Shibata · 2015 · Cancer drug discovery and develogment/Cancer drug discovery and development
  23. Necrobiology of Liver Cancer: Necrosis and Necroptosis
    Arthur Zimmermann · 2016 · Springer eBooks
  24. TRAIL-induced kinases activation and apoptosis: towards improved death receptor targeted therapy for lung cancer
    Kaamar Azijli · 2013 · Pure Amsterdam UMC
  25. Nouvelles voies de mort cellulaire des hépatocytes
    Aveline A. Filliol, Jacques Le Seyec, Marie‐Françoise Samson · 2017
  26. The Role of NFκB Factor Relish in Developmentally Programmed Cell Death
    Anubhab Nandy · 2018 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  27. Pro-necroptotic agents in cancer therapy
    Ahmed M Elsharkawy, Ahmed M Malki · 2018 · Annals of Breast Cancer
  28. Targeting Necroptosis as Therapeutic Potential in Central Nervous System Diseases
    Hao Li, Meiling Xia, Jing Chen, Richard M. Kostrzewa, Xingshun Xu · 2021 · Springer eBooks
  29. Potent and Selective RIPK1 Inhibitors Targeting Dual‐Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
    Xiangbo Yang, Huimin Lu, Hang Xie, Binbin Zhang, Tianqing Nie, Chen Fan, Tao Yang, Yechun Xu, Haixia Su, Wei Tang et al. · 2021 · Angewandte Chemie
  30. TNF signaling
    Amrit Mann, Mark J. Czaja, Jörn Markus Schattenberg · 2015 · Wiley eBooks
  31. Necrobiology of Liver Cancer: Necrosis and Necroptosis
    Arthur Zimmermann · 2016 · Springer eBooks
  32. APO2L/TRAIL
    Luis Martínez‐Lostao, Diego de Miguel, Alberto Anel, Javier Naval · 2016 · Springer eBooks
  33. APO2L/TRAIL
    Luis Martínez‐Lostao, Diego de Miguel, Alberto Anel, Javier Naval · 2017 · Springer eBooks
  34. ROS/Redox Signaling and Apoptosis/Necroptosis/Autophagy in Cancer
    Mohinder Pal Bansal · 2023 · Springer eBooks
  35. Novel functions of LUBAC-mediated M1 poly-ubiquitination in TNFR1-mediated necroptosis
    Nadine Weinelt · 2024
  36. Cell Death Mechanisms, Associated Toxicity and Therapeutic Applications
    Julio C Davila, Natalia Kovalova, Zaher A. Radi · 2025 · Elsevier eBooks
  37. TRAIL (DR5) receptor and the modulation of TRAIL pathway in PLWHIV: key mechanisms in the progression of HIV disease
    Sarah Ratkovich-González, Mariana del Rocío Ruiz-Briseño, Judith Carolina De Arcos-Jiménez, Monserrat Álvarez-Zavala, Jaime Federico Andrade-Villanueva, Pedro Martínez-Ayala, Vida Verónica Ruíz-Herrera, Luz Alicia González-Hernández, Karina Sánchez-Reyes · 2025 · BMC Molecular and Cell Biology
  38. Inflammatory cell death and leukemia treatment
    Saqib Ishaq, Sajida Afzal, Shabir Ahmad Usmani, Ibtasam Wajid, Abdul Aziz, Raheel Tahir, Ajaz Ahmad, Amin Ullah · 2025 · Critical Reviews in Oncology/Hematology
  39. NEUROCOGNITION, PLASMA LEVEL OF TUMOUR NECROSIS FACTORRELATED APOPTOSIS INDUCING LIGAND (TRAIL), AND PHAGOCYTIC ACTIVITY IN HIV PATIENTS ON LONG-TERM ANTIRETROVIRAL THERAPY.
    Sheu Kadiri Rahamon, T B Kasali, Abdulfatah Adekunle Onifade, Sunday Peter Ogundeji, OLATUBOSUN GANIYU ARINOLA · 2025 · PubMed Central
  40. Advances in Pseudomonas aeruginosa-Induced Programmed Cell Death and Potential Targeted Treatment Strategies
    Chunjiang Tan, Yifeng Luo · 2025 · Microorganisms
  41. Additional file 1 of Unlocking cardioprotection: iPSC exosomes deliver Nec-1 to target PARP1/AIFM1 axis, alleviating HF oxidative stress and mitochondrial dysfunction
    Xiaobing Lv, Boqin Liu, Xiaoting Su, Xintao Tian, Wang, Huating · 2024 · Figshare
  42. Additional file 2 of Unlocking cardioprotection: iPSC exosomes deliver Nec-1 to target PARP1/AIFM1 axis, alleviating HF oxidative stress and mitochondrial dysfunction
    Xiaobing Lv, Boqin Liu, Xiaoting Su, Tian, Xintao, Wang, Huating · 2024 · Figshare
  43. Additional file 3 of Unlocking cardioprotection: iPSC exosomes deliver Nec-1 to target PARP1/AIFM1 axis, alleviating HF oxidative stress and mitochondrial dysfunction
    Xiaobing Lv, Boqin Liu, Xiaoting Su, Tian, Xintao, Wang, Huating · 2024 · Figshare
  44. Role of TRAIL-receptors in apoptosis and nonapoptotic signaling in cancer cells populations undergoing fractional killing
    Yelyzaveta Shlyakhtina · 2016
  45. Caractérisation de nouveaux inhibiteurs de la kinase RIPK1 et de la nécroptose
    Fabienne Le Cann · 2017 · theses.fr (ABES)
  46. Mise en place et étude de modèles de progression de la NASH jusqu’au développement du CHC : effet du régime hyperlipidique sur l’environnement hépatique
    Mélanie Simoes Eugénio · 2019
  47. Role of RIPK1 in the survival and death of hepatocytes : its involvement in murine hepatitis models
    Muhammad Farooq · 2019 · theses.fr (ABES)
  48. Étude de l’origine moléculaire de l’hétérogénéité de réponse cellulaire à TRAIL et son rôle dans la résistance non-génétique
    Mickaël Meyer · 2020 · theses.fr (ABES)
  49. Caractérisation moléculaire et fonctionnelle de deux nouveaux déficits immunitaires primitifs associés à une dérégulation de la mort cellulaire
    Boris Sorin · 2023
  50. The resveratrol-induced apoptosis and/or necroptosis of lung cancer cells is dependent on the activation status of PARP-1 and MLKL under oxidative stress
    Gwan-Hwan Wi, Seon‐Hee Oh · 2026 · Toxicological Research
  51. Redox-modulation of regulated cell death: implications for synergistic anticancer therapies
    Pooja Singh, Shreya Sridhar, Dwarithaa Balasubramanian, Devi Maigandan, Harish Chinna Konda Chandramoorthy, T T Ganesan, Rajesh Kumar Gandhirajan · 2026 · Naunyn-Schmiedeberg s Archives of Pharmacology
  52. Species-specific regulation of necroptosis by STK38-dependent RIPK1 phosphorylation
    Seongmi Kim, Seung Ri Lee, Hyunjin K. Rho, Hye-Jung Kim, Hyuk Wan Ko, Dong Hyuk Shin, Seung‐Mo Hong, Minjoong Kim, Jiyoung Yu, Kyunggon Kim et al. · 2026 · Cell Death and Differentiation
  53. Integrated Necroptosis Within Programmed Cell Death in Traumatic Brain Injury
    Ao Li, Tian-Wei Pei, Hao Qi, Juan Fang, Zhi‐Song Ding, Yu Wang, Yu-qiang Zhang, Tao Chen · 2026 · Molecular Neurobiology
  54. TRAIL splice variant TRAILshort disrupts T cell receptor signaling and promotes immune tolerance in vivo
    Shahrzad Jalali, Sekar Natesampillai, Zilin Nie, Ying Zhang, İsmail Can, Aswath P. Chandrasekar, Brianna M. Hameister, Cristina Correia, Tuantuan V. Zhao, Dong‐Gi Mun et al. · 2026 · Journal of Clinical Investigation
  55. Host- and genotype-specific transcriptomic responses to Mycoplasma bovis infection in bison and Holstein peripheral blood mononuclear cells
    Bryan S. Kaplan, Kaitlyn M. Sarlo Davila, Jamison Ray Slate, Steven C. Olsen, Rohana P. Dassanayake, David J. Holthausen, Daniel W. Nielsen, Randy E. Sacco · 2026 · Frontiers in Immunology
  56. E3 ubiquitin ligase-mediated necroptosis: regulatory mechanisms and therapeutic implication in cancer
    Mingzhen Wei, Aiqin Sun · 2026 · Molecular Biology Reports
  57. BindingDB Entry 50020763: Discovery of Sibiriline derivatives as novel receptor-interacting protein kinase 1 inhibitors.
    BindingDB · 2024 · UC San Diego
  58. BindingDB Entry 50017144: Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors.
    BindingDB · 2023 · UC San Diego
  59. BindingDB Entry 50049028: Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
    BindingDB · 2019 · UC San Diego
  60. BindingDB Entry 50013369: Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1.
    BindingDB · 2022 · UC San Diego
  61. BindingDB Entry 50015323: Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity.
    BindingDB · 2023 · UC San Diego
  62. BindingDB Entry 50007823: Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
    BindingDB · 2021 · UC San Diego