The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Autosis and autophagic cell death: the dark side of autophagy
Open accessAbstract
It is controversial whether cells truly die via autophagy or whether - in dying cells - autophagy is merely an innocent bystander or a well-intentioned 'Good Samaritan' trying to prevent inevitable cellular demise. However, there is increasing evidence that the genetic machinery of autophagy may be essential for cell death in certain settings. We recently identified a novel form of autophagy gene-dependent cell death, termed autosis, which is mediated by the Na(+),K(+)-ATPase pump and has unique morphological features. High levels of cellular autophagy, as occurs with treatment with autophagy-inducing peptides, starvation, or in vivo during certain types of ischemia, can trigger autosis. These findings provide insights into the mechanisms and strategies for prevention of cell death during extreme stress conditions.
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Cites
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Self-citationRole of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
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BackgroundExercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
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Self-citationIdentification of a candidate therapeutic autophagy-inducing peptide
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BackgroundInfluentialSelf-citationGrowth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
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Cited by
Autophagy promotes ferroptosis by degradation of ferritin
Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M. T., Zeh, H. J., Kang, R., & Tang, D. (2016) · Autophagy · doi:10.1080/15548627.2016.1187366 · Cited by 2,332
Ferroptosis is an autophagic cell death process
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Mitochondrial dysfunction in neurodegenerative disorders
Klemmensen, M. M., Borrowman, S. H., Pearce, C., Pyles, B., & Chandra, B. (2024) · Neurotherapeutics · doi:10.1016/j.neurot.2023.10.002 · Cited by 396
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis
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Modulation of inflammation by autophagy: Consequences for human disease
Netea-Maier, R. T., Plantinga, T. S., van de Veerdonk, F. L., Smit, J. W., & Netea, M. G. (2016) · Autophagy · doi:10.1080/15548627.2015.1071759 · Cited by 349
Metadata
- Authors
- Liu, Y., & Levine, B.
- Venue
- Cell Death & Differentiation
- Published
- 2014-09-26
- Volume
- 22
- Issue
- 3
- Pages
- 367-376
- ISSN
- 1350-9047 (ISSN-L)
- 1476-5403
- OpenAlex
- W2054580728
- Cited by
- 742
- References
- 22
- FWCI
- 40.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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