Sulfamethoxazole is metabolized to the hydroxylamine in humans
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Items 101–175 of 175
- Role of drug metabolism for breaking tolerance and the localization of drug hypersensitivityJack Uetrecht · 2005 · Toxicology
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- Molecular mechanisms of adverse drug reactionsSidney D. Nelson · 2001 · Current Therapeutic Research
- Immunological principles of T-cell-mediated adverse drug reactions in skinDean John Naisbitt, Munir Pirmohamed, B. Kevin Park · 2007 · Expert Opinion on Drug Safety
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- Pharmacokinetics of sulfamethoxazole with its hydroxy metabolites and N4-acetyl-, N1-glucuronide conjugates in healthy human volunteersVree, Tom B., van der Ven, André J.A.M., Koopmans, Peter P., van Ewijk-Beneken Kolmer, Eleonora W.J., Verwey-van Wissen, Corrien P.W.G.M. · 1995 · Clinical Drug Investigation
- Sensitization of mice to topically applied drugs: albuterol chlorpheniramine, clonidine and nadololRichard S. Kalish, Jonathan A. Wood, John J. Wille, Agis F. Kydonieus · 1996 · Contact Dermatitis
- Suppression of pokeweed mitogen-driven human IgM and IgG responses by the hydroxylamine of sulfamethoxazoleMargaret E. Sisson, Michael John Rieder, Ingrid A. Bird, Wassim Youssef Almawi · 1997 · International Journal of Immunopharmacology
- Proteomic analysis reveals that sulfamethoxazole induces oxidative stress in M. tuberculosisRajesh Sarkar, C. Mdladla, Lubabalo Macingwana, Ray‐Dean Pietersen, Andile H. Ngwane, David L. Tabb, Paul D. van Helden, Ian J. F. Wiid, Bienyameen Baker · 2018 · Tuberculosis
- Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4 T-cellsJ HOPKINS, Dean John Naisbitt, N HUMPHREYS, Rebecca Jane Dearman, Ian Kimber, B PARK · 2004 · Toxicology
- BioactivationJack Uetrecht · 2003 · Informa Healthcare eBooks
- Lessons from drug allergy: Against dogmataWerner J. Pichler · 2003 · Current Allergy and Asthma Reports
- An evidence-based approach for providing cautionary recommendations to sulfonamide-allergic patients and determining cross-reactivity among sulfonamide-containing medicationsSaurav Ghimire, E Lee Kyung, J. H. Lee, J. W. Kim, W. Kang, E. Kim · 2013 · Journal of Clinical Pharmacy and Therapeutics
- Inhibition of cytokine production and interference in IL‐2 receptor‐mediated Jak‐Stat signaling by the hydroxylamine metabolite of sulfamethoxazoleDavid A. Hess, Erin F. O'Leary, James Tseryuan Lee, Wassim Youssef Almawi, Joaquı́n Madrenas, Michael John Rieder · 2001 · The FASEB Journal
- Acute delirium induced by intravenous trimethoprim–sulfamethoxazole therapy in a patient with the Acquired Immunodeficiency SyndromeAlan R. Salkind · 2000 · Human & Experimental Toxicology
- Drug‐Induced Liver DiseaseShivakumar Chitturi, Geoffrey C. Farrell · 2011 · Wiley eBooks
- Bioactivation of benzocaine to a methaemoglobin-forming metabolite by rat and human microsomes in vitroMichael D. Coleman, Claire H. Taylor · 1997 · Environmental Toxicology and Pharmacology
- Pharmacogenetics and blood dyscrasiasStephen P. Spielberg · 1996 · European Journal Of Haematology
- Drug allergy: relationship between immunogenicity and clinical symptomsWerner J. Pichler · 1999 · Allergy
- HIV-1 tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cellsKemi Adeyanju, John Richard Bend, Michael John Rieder, Gregory A. Dekaban · 2018 · Virology Journal
- The Hydroxylamine of Sulfamethoxazole Synergizes with FK506 and Cyclosporin A, Inhibiting T-Cell ProliferationDavid A. Hess, Ingrid A. Bird, Wassim Youssef Almawi, Michael John Rieder · 1997 · Journal of Pharmacology and Experimental Therapeutics
- Drug-Induced Liver DiseaseEve A. Roberts · 2007 · Cambridge University Press eBooks
- Extrahepatic Targets and Cellular Reactivity of Drug MetabolitesHi̇lmi̇ Orhan · 2014 · Current Medicinal Chemistry
- Improvement of sulfamethoxazole (SMX) elimination and inhibition of formations of hydroxylamine-SMX and N4-acetyl-SMX by membrane bioreactor systemsMin‐Hui Tang, Nan Gao, Jiao Zhou, Yan Zhao, Jing‐Sheng Cheng, Wen-Kun Su, Ying‐Jin Yuan · 2018 · Biodegradation
- Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolitesSanderson, Joseph P., Hollis, Frank J., Maggs, James L., Clarke, Stephen E., Naisbitt, Dean J., Park, B. Kevin · 2008 · Drug Metabolism and Disposition
- Comprehensive insights into the formation of metabolites of the ghrelin mimetics capromorelin, macimorelin and tabimorelin as potential markers for doping control purposesTobias Lange, Andreas Thomas, Christian Görgens, Martin Bidlingmaier, Katharina Schilbach, Eric Fichant, Philippe Delahaut, Mario Thevis · 2021 · Biomedical Chromatography
- Section Review Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis: Drug-induced lupus: Possible mechanisms and their implications for prediction of which new drugs may induce lupusJack Uetrecht · 1996 · Expert Opinion on Investigational Drugs
- Quaternary Cu2ZnSnS4 and Cu2ZnSnS4-WS2 composite for enhanced antioxidant, antibacterial, and photocatalyst for degradation of sulfamethoxazoleNur Jalal Mondal, Rahul Sonkar, Mridusmita Barman, Mritunjoy Prasad Ghosh, Devasish Chowdhury · 2024 · Journal of Photochemistry and Photobiology A Chemistry
- The Effect of Cimetidine on the Formation of Sulfamethoxazole Hydroxylamine in Patients with Human Immunodeficiency VirusDavid F. Lehmann, Nancy B. Newman, Philo Morse · 1998 · The Journal of Clinical Pharmacology
- Allergy to antibacterials: the problem with beta-lactams and sulfonamidesAndreas Cerny, Werner J. Pichler · 1998 · Pharmacoepidemiology and Drug Safety
- Towards the development of mechanism-based biomarkers to diagnose drug hypersensitivityNoé Durán‐Figueroa, Jesús Agustín Badillo-Corona, Dean John Naisbitt, José Luis Castrejón-Flores · 2015 · Toxicology Research
- Assessment of arylamine N‐acetyltransferase (NAT1) activity in mononuclear leukocytes of cystic fibrosis patients.Alastair E. Cribb, Ban C. H. Tsui, Richard A. Isbrucker, RT Michael, C. T. Gillespie, J Brown‐Bonomo, P Barrett, Terry L. LeVatte, K W Renton · 1995 · British Journal of Clinical Pharmacology
- Mécanismes immunologiques des réactions cutanées aux médicamentsEwa Poszepczynska-Guigné, Jean E. Revuz, Jean‐Claude Roujeau · 2005 · Annales de Dermatologie et de Vénéréologie
- Antibacterial Agents, SulfonamidesMichele A. Weidner‐Wells, Mark J. Macielag · 2003 · Wiley eBooks
- Adverse reactions to trimethoprim-sulfamethoxazoleBelle L. Lee · 1996 · Clinical Reviews in Allergy & Immunology
- T Cell Responses to Drugs and Drug MetabolitesCaroline J. Earnshaw, Tatjana Pecaric-Petkovic, B. K. Park, Dean John Naisbitt · 2013 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
- Cytotoxicity testing of β-lactam antibiotics, non-steroidal anti-inflammatory drugs and sulfonamides in primary human keratinocyte culturesM. PATOUX-PiBOUIN, Béatrice Hirel, Christophe Chesné, Éric Watier, Jacqueline Chevrant‐Breton, André Guillouzo · 1995 · Toxicology in Vitro
- An Update on the Immunological, Metabolic and Genetic Mechanisms in Drug Hypersensitivity ReactionsCristobalina Mayorga, Maria Isabel Montañez, Raquel Jurado‐Escobar, Violeta Gil-Ocaña, José Antonio Cornejo-García · 2019 · Current Pharmaceutical Design
- Activation of the TCR Complex by Small Chemical CompoundsChristine Louis-Dit-Sully, Wolfgang W A Schamel · 2013 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
- Improving Drug Design: Considerations for the Structural Modification ProcessAla F. Nassar · 2010 · Wiley eBooks
- Adverse drug reaction monitoring in JenaRelevance of polymorphic drug metabolizing enzymes for inducing adverse drug reactionsMarion Hippius, Christiane Buchardt, Katrin Farker, U KUHN, Ilselore R. Reimann, Andreas Hoffmann · 2003 · Experimental and Toxicologic Pathology
- Development and Validation of RP-HPLC Method for Quantitative Analysis of Sulfamethoxazole and Trimethoprim in Liquid Suspension: A Comparative Study with Compendial MethodMuhammad Aslam, Shahzad M. Ali, Mahmood Ahmed, Muhammad Aneeq Javed, Afsah Iftikhar, Yousaf Abbas, Aamir Sohail, Mehvish Abdul-Rehman, Khansa Habibullah · 2023 · Scientific Inquiry and Review
- Insights on aggregation-algae consortium based removal of sulfamethoxazole: Unraveling removal effect, enhanced method and toxicological evaluationYongtao Cheng, Yuanyuan Wu, Chuanyue Peng, Yang Yang, Liang Xuan, Lin Wang, Yan Wang, An Xu, Ying Liu · 2024 · Journal of Environmental Management
- Classifying the Transformation Products (TPs) of Emerging Contaminants (ECs) for Prioritizing Research into their Impact on the Environment and Human HealthJacek Namieśnik, Lidia Wolska, Radosław Czernych, Grażyna Gałęzowska, Monika Cieszyńska-Semenowicz · 2014 · Wiley eBooks
- Chemical Structural Alert and Reactive Metabolite Concept as Applied in Medicinal Chemistry to Minimize the Toxicity of Drug CandidatesAla F. Nassar · 2022 · Wiley eBooks
- The stress response and removal mechanism of Chlorella vulgaris to sulfamethoxazoleChen Liang, Yuanyuan Zhou, Yifei Zhou, Penglan Zhu, Chun-Li Yu, Yali Luo, Jielian Wu, Qingsong Zhou, Wenkui Li, Shanshan Luo · 2025 · Algal Research
- Cutaneous drug reactions with systemic featuresSimon Robert Knowles, Neil H. Shear · 2013 · Elsevier eBooks
- Populations at risk: Predicting and preventing drug-induced diseaseStephen P. Spielberg · 1993 · Pharmacoepidemiology and Drug Safety
- Pathophysiologic Mechanisms of Immune-mediated Drug Hypersensitivity Reactions to SulfonamidesElham A. Sultan · 2015 · Scholarship@Western (Western University)
- Sulfonamide-induced cutaneous drug reactionsPiyush M. Vyas · 2006
- Traitement des effluents d’un service d’oncologie par bioréacteur à membranes : faisabilité d’acclimatation et gain apporté sur l’élimination de molécules médicamenteusesPierre Hamon · 2014 · theses.fr (ABES)
- N-Acetyltransferase (NAT) 1 and NAT2 Enzyme Activities Drive Interindividual Variability in Sulfamethoxazole N-AcetylationLanphier, Raeanne M., Latham, Bethany D., Gerringer, Amanda J., Interrante, Tyler, Jones, Corbin D., De Buysscher, Tristan, Fallon, John K., Jackson, Klarissa D. · 2025 · Drug Metabolism and Disposition
- Drug hypersensitivity reactionsM. Blanca, Bernard Yu‐Hor Thong · 2015 · Current Opinion in Allergy and Clinical Immunology
- IsoxazoleErum Akbar Hussain, Ambreen Ghani, Zubi Sadiq · 2024 · Elsevier eBooks
- Adverse drug reaction monitoring in JenaMarion Hippius, Christiane Buchardt, Katrin Farker, Urs Dieter Kuhn, Ilselore R. Reimann, Annemarie Hoffmann · 2003 · Experimental and Toxicologic Pathology
- Workshop Session: MONDAY, JUNE 3, 19961996 · Allergy
- Minimizing the Potential for Drug Bioactivation of Drug Candidates to Success in Clinical DevelopmentAla F. Nassar · 2008 · Wiley eBooks
- Pediatric Hepatic Drug ReactionsEve A. Roberts · 1996 · Handbook of experimental pharmacology
- Hypersensitivity Syndrome ReactionSimon Robert Knowles, Neil H. Shear · 2010 · Springer eBooks
- EFFECT OF COMBINATION EXPOSURE TO ZIDOVUDINE AND SULFAMETHOXAZOLE-TRIMETHOPRIM ON IMMUNE RESPONSE IN MICE AND HUMANSDavid J. Feola · 2005 · UKnowledge (University of Kentucky)
- Minimizing the Potential for Drug Bioactivation of Drug Candidates to Success in Clinical DevelopmentAla F. Nassar · 2010 · Wiley eBooks
- Genetically Determined Polymorphisms in Drug MetabolismY. W. Francis Lam, Milton V. Marshall · 1992 · Journal of Pharmacy Practice
- A. Classification of Drug HepatotoxicityEve A. Roberts · 1996
- Role of Microorganisms in Degradation and Removal of Anticonvulsant Drugs: A ReviewNeha Alok Sinha, Vipin Kumar · 2019 · Energy, environment, and sustainability
- Cutaneous Drug Reactions With Systemic FeaturesSimon Robert Knowles, Lori E. Shapiro, Neil H. Shear · 2020 · Elsevier eBooks
- Exvotos inéditos de Despeñaperros en la colección A. Aguirre, de BilbaoCarmelo Fernández Ibáñez · 1984 · Boletín del Instituto de Estudios Giennenses
- Immunological Mechanisms of Cutaneous Adverse Drug ReactionsE. Guigné, Jean E. Revuz, Jean‐Claude Roujeau · 2004 · CRC Press eBooks
- Drug ReactionsHans Friedrich Merk, Daniela Hoeller Obrigkeit · 2010 · Springer eBooks
- Drug allergy: relationship between immunogenicity and clinical symptomsWerner J. Pichler · 1996 · Allergy
- Exanthematic ReactionsSimon Robert Knowles, Neil H. Shear · 2014
- Drug allergy: relationship between immunogenicity and clinical symptomsWerner J. Pichler · 1999 · Allergy
- Adverse Reactions to Trimethoprim-SulfamethoxazoleBelle L. Lee · 1997 · Humana Press eBooks
- Clinical Study on Penicillin Anaphylaxis and Role of Oxidative Stress and Pro-inflammatory Markers: An Implication for TherapyShowkat Ul Nabi, Abrar Ul Haq, Showkeen Muzamil, Hafiz Antar Makeen, Mohammed Al Bratty, Andleeb Khan · 2022 · Indian Journal of Animal Research
- Antibiotic-targeted water treatment with cost-effective bioadsorbentsAnna Viktória Vancsik · 2024 · Scientia et Securitas