The endless tale of non-homologous end-joining

Weterings, Eric, Chen, David J·2008·Cell Research

DOI 10.1038/cr.2008.3

Cited by (417)

Items 101–200 of 417

Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value
Matthias Evert, Maddalena Frau, Maria Lauda Tomasi, Gavinella Latte, M M Simile, Maria Antonietta Seddaiu, Antje Zimmermann, Sara Ladu, Tommaso Staniscia, Stefania Brozzetti et al. · 2013 · British Journal of Cancer
Sublethal Doses of β-Amyloid Peptide Abrogate DNA-dependent Protein Kinase Activity
Alessio Cardinale, Mauro Racaniello, Serena Saladini, Giovanna De Chiara, Cristiana Mollinari, Maria Chiara de Stefano, Maurizio Pocchiari, Enrico Garaci, Daniela Merlo · 2011 · Journal of Biological Chemistry
Participation of DNA-PKcs in DSB Repair after Exposure to High- and Low-LET Radiation
Jennifer A. Anderson, Jane V. Harper, Francis A. Cucinotta, Peter O’Neill · 2010 · Radiation Research
The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining
Robert Hromas, Justin W. Wray, Suk‐Hee Lee, Leah Martinez, Jacqueline Farrington, Lori Corwin, H. E. Ramsey, Jac A. Nickoloff, Elizabeth A. Williamson · 2008 · DNA repair
Template strand scrunching during DNA gap repair synthesis by human polymerase λ
Miguel García–Díaz, Katarzyna Bębenek, Andres A. Larrea, Jody M. Havener, L. Perera, Joseph M. Krahn, Lars Christian Pedersen, Dale A. Ramsden, Thomas A. Kunkel · 2009 · Nature Structural & Molecular Biology
The vital link between the ubiquitin–proteasome pathway and DNA repair: Impact on cancer therapy
Akira Motegi, Yasuhiro Murakawa, Shunichi Takeda · 2009 · Cancer Letters
Yeast Nej1 Is a Key Participant in the Initial End Binding and Final Ligation Steps of Nonhomologous End Joining
Xi Chen, Alan E. Tomkinson · 2010 · Journal of Biological Chemistry
Recent Progress and Challenges in CRISPR-Cas9 Engineered Algae and Cyanobacteria
Patel, Vikas Kumar, Das, Anima, Kumari, Ritu, Kajla, Sachin · 2023 · Algal Research
Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair
Rui R Liu, Jingyi Li, Jichun Shao, Jong-Ho Lee, Xuemei Qiu, Yanxuan Xiao, Bowen Zhang, Yilong Hao, Mi Li, Qianming Chen · 2021 · Cell Metabolism
Hyperthermia inhibits homologous recombination repair and sensitizes cells to ionizing radiation in a time‐ and temperature‐dependent manner
Stefan C. Genet, Yoshihiro Fujii, Junko Maëda, Masami Kaneko, MATTHEW D. GENET, Kiyoshi Miyagawa, Takamitsu A. Kato · 2012 · Journal of Cellular Physiology
Radiation-generated Short DNA Fragments May Perturb Non-homologous End-joining and Induce Genomic Instability
Dalong Pang, Thomas A. Winters, Mira Jung, Shubhadeep Purkayastha, Luciane R. Cavalli, Sergey CHASOVKIKH, Bassem R. Haddad, Anatoly Dritschilo · 2011 · Journal of Radiation Research
DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response
Yu‐Fen Lin, Hung-Ying Shih, Zeng‐Fu Shang, Shinji Matsunaga, Benjamin P.C. Chen · 2014 · Nucleic Acids Research
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages
Hongyi Qi, Zhuyun Jiang, Chengqiang Wang, Yi Yang, Li Li, Hui He, Zanyang Yu · 2017 · Oncotarget
Early Increase of Radiation-induced γH2AX Foci in a Human Ku70/80 Knockdown Cell Line Characterized by an Enhanced Radiosensitivity
Veerle Vandersickel, Julie Depuydt, Bram VAN BOCKSTAELE, Gianpaolo Perletti, Jan Philippé, Hubert Thierens, Anne Vral · 2010 · Journal of Radiation Research
Mind the gap: keeping UV lesions in check
Novarina, Daniele, Amara, Flavio, Lazzaro, Federico, Plevani, Paolo, Muzi-Falconi, Marco · 2011 · DNA Repair
RAG2’s Acidic Hinge Restricts Repair-Pathway Choice and Promotes Genomic Stability
Marc Coussens, Rebecca L. Wendland, Ludovic Deriano, Cory Lindsay, Suzzette M. Arnal, David B. Roth · 2013 · Cell Reports
Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells
Sanna Abbasi, Caroline Schild‐Poulter · 2018 · Journal of Proteome Research
Aberrant DNA Damage Response Pathways May Predict the Outcome of Platinum Chemotherapy in Ovarian Cancer
Dimitra T. Stefanou, Aristotelis Bamias, Hara G. Episkopou, Soterios Α. Kyrtopoulos, Maria Likka, Theodore Kalampokas, Stylianos Fotiou, Nikos G. Gavalas, Petros Paul Sfikakis, Meletios Athanasios Dimopoulos et al. · 2015 · PLoS ONE
In vitro studies of DNA damage and repair mechanisms induced by BNCT in a poorly differentiated thyroid carcinoma cell line
Carla Rodriguez, Marina Carpano, Paula M. Curotto, Silvia Ines Thorp, Mariana Casal, Guillermo Juan Juvenal, Mario Alberto Pisarev, María Alejandra Dagrosa · 2018 · Radiation and Environmental Biophysics
DNA-PKcs Inhibition Sensitizes Cancer Cells to Carbon-Ion Irradiation via Telomere Capping Disruption
Xin Hua Zhou, Xin Zhang, Yi Xie, Kaoru Tanaka, Bing Wang, Hong Zhang · 2013 · PLoS ONE
Radiation Responses of 2D and 3D Glioblastoma Cells: A Novel, 3D-specific Radioprotective Role of VEGF/Akt Signaling through Functional Activation of NHEJ
Natividad Gomez-Roman, Ming Yao Chong, Sandeep K. Chahal, Seamus P. Caragher, Mark R. Jackson, Katrina H. Stevenson, Sidhartha A. Dongre, Anthony J. Chalmers · 2019 · Molecular Cancer Therapeutics
Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice
Shinichiro Nakada · 2016 · Journal of Radiation Research
Progress in Gene-Editing Technology of Zebrafish
Yanling Li, Zhipeng Jia, Shuchao Zhang, Xiaozhen He · 2021 · Biomolecules
The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk
Jorge Gaspar · 2010 · Oncology Reports
DNA Methylation and Establishing Memory
Carol Bernstein · 2022 · Epigenetics Insights
The rice RAD51C gene is required for the meiosis of both female and male gametocytes and the DNA repair of somatic cells
Yanjun Kou, Yuxiao Chang, Xianghua Li, Jinghua Xiao, Shiping Wang · 2012 · Journal of Experimental Botany
Influence of Hypoxia on Tumor Heterogeneity, DNA Repair, and Cancer Therapy: From Molecular Insights to Therapeutic Strategies
Dominika Kunachowicz, Paulina Tomecka, Mikołaj Sędzik, Jarosław Kalinin, Jacek Kuźnicki, Nina Rembiałkowska · 2025 · Cells
Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks
Anthony J. Davis, Sairei So, David J. Chen · 2010 · Cell Cycle
Differential Role of DNA-PKcs Phosphorylations and Kinase Activity in Radiosensitivity and Chromosomal Instability
Hatsumi Nagasawa, John B. Little, Yu‐Fen Lin, Sairei So, Akihiro Kurimasa, Yuanlin Peng, John R. Brogan, David J. Chen, Joel S. Bedford, Benjamin P.C. Chen · 2010 · Radiation Research
Inefficient Double-Strand Break Repair in Murine Rod Photoreceptors with Inverted Heterochromatin Organization
Antonia Frohns, Florian Frohns, Steffen C. Naumann, Paul Gottlob Layer, Markus Löbrich · 2014 · Current Biology
Transposon Invasion of theParameciumGermline Genome Countered by a Domesticated PiggyBac Transposase and the NHEJ Pathway
Emeline Dubois, Julien Bischerour, Antoine Marmignon, Nathalie Mathy, Vinciane Régnier, Mireille Bétermier · 2012 · International Journal of Evolutionary Biology
In vitro non-homologous DNA end joining assays—The 20th anniversary
Elżbieta Pastwa, Richard Idem Somiari, Mariusz Malinowski, Stella Somiari, Thomas A. Winters · 2008 · The International Journal of Biochemistry & Cell Biology
Mutual regulation between DNA-PKcs and snail1 leads to increased genomic instability and aggressive tumor characteristics
B-J Pyun, H R Seo, H-J Lee, Yeung Bae Jin, EJ Kim, Nam Hee Kim, Hyun Sil Kim, H W Nam, Jong In Yook, Y-S Lee · 2013 · Cell Death and Disease
No country for old methods: New tools for studying microproteins
Fabiola Valdivia-Francia, Ataman Sendoel · 2024 · iScience
Putative binding modes of Ku70-SAP domain with double strand DNA: a molecular modeling study
Shaowen Hu, Janice M. Pluth, Francis A. Cucinotta · 2011 · Journal of Molecular Modeling
Intracellular Signal Transduction and Modification of the Tumor Microenvironment Induced by RET/PTCs in Papillary Thyroid Carcinoma
Elisa Menicali, Sonia Moretti, Pasquale Voce, Serena Romagnoli, Nicola Avenia, Efisio Puxeddu · 2012 · Frontiers in Endocrinology
C9orf72 functions in the nucleus to regulate DNA damage repair
Liying He, Jiaqi Liang, Chao-Nan Chen, Jijun Chen, Yihui Shen, Shuangshuang Sun, Lei Li · 2022 · Cell Death and Differentiation
Bacteriophage T4 Escapes CRISPR Attack by Minihomology Recombination and Repair
Xiaorong Wu, Jingen Zhu, Tao Pan, Venigalla Basaveswara Rao · 2021 · mBio
The combination of chemotherapy with HVJ-E containing Rad51 siRNA elicited diverse anti-tumor effects and synergistically suppressed melanoma
Eiji Kiyohara, Katsuto Tamai, Ichiro Katayama, Yasufumi Kaneda · 2011 · Gene Therapy
Multiple host‐cell recombination pathways act in A grobacterium ‐mediated transformation of plant cells
Imen Mestiri, Frédéric Norre, Maria Eugenia Gallego, Charles I. White · 2013 · The Plant Journal
Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining
Takashi Ochi, B. L. Sibanda, Qian Wu, Dimitri Y. Chirgadze, Víctor M. Bolaños-García, Tom L. Blundell · 2010 · Journal of Nucleic Acids
Tools to study DNA repair: what's in the box?
Sascha Feuerhahn, Jean‐Marc Egly · 2008 · Trends in Genetics
Herpes Simplex Virus-Type1 (HSV-1) Impairs DNA Repair in Cortical Neurons
Giovanna De Chiara, Mauro Racaniello, Cristiana Mollinari, Maria Elena Marcocci, Giorgia Aversa, Alessio Cardinale, Anna Giovanetti, Enrico Garaci, Anna Teresa Palamara, Daniela Merlo · 2016 · Frontiers in Aging Neuroscience
The radiosensitizing effect of Ku70/80 knockdown in MCF10A cells irradiated with X-rays and p(66)+Be(40) neutrons
Veerle Vandersickel, Monica Mancini, Jacobus P. Slabbert, Emanuela Marras, Hubert Thierens, Gianpaolo Perletti, Anne Vral · 2010 · Radiation Oncology
Next-Generation DNA Curtains for Single-Molecule Studies of Homologous Recombination
Michael M. Soniat, Logan R. Myler, Jeffrey M. Schaub, Yoori Kim, Ignacio F. Gallardo, Ilya J. Finkelstein · 2017 · Methods in enzymology on CD-ROM/Methods in enzymology
Further delineation of nonhomologous-based recombination and evidence for subtelomeric segmental duplications in 1p36 rearrangements
Carla Sustek D’Angelo, Marzena Gajęcka, Chong Ae Kim, Andrew J. Gentles, Caron D. Glotzbach, Lisa G. Shaffer, Célia Priszkulnik Koiffmann · 2009 · Human Genetics
Efficient ligase 3-dependent microhomology-mediated end joining repair of DNA double-strand breaks in zebrafish embryos
Mudan He, Fenghua Zhang, Huálín Wáng, Hou-Peng Wang, Zuoyan Zhu, Yonghua Sun · 2015 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1
Ali Bakr, Sabrina Köcher, Jennifer Volquardsen, Cordula Petersen, Kerstin Borgmann, Ekkehard Dikomey, Kai Rothkamm, Wael Yassin Mansour · 2016 · Oncotarget
A Non-Sequence-Specific DNA Binding Mode of RAG1 Is Inhibited by RAG2
Shuying Zhao, Lori M. Gwyn, Pallabi De, Karla K. Rodgers · 2009 · Journal of Molecular Biology
Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells
Shay Covo, Jean‐Pierre de Villartay, Penny Ann Jeggo, Zvi Livneh · 2009 · Nucleic Acids Research
Development of Novel Visual-Plus Quantitative Analysis Systems for Studying DNA Double-Strand Break Repairs in Zebrafish
Jin‐Gang Liu, Lu Gong, Changqing Chang, Cong Liu, Jinrong Peng, Jun Chen · 2012 · Journal of genetics and genomics/Journal of Genetics and Genomics
Nonhomologous DNA End Joining in Cell‐Free Extracts
Sheetal Sharma, Sathees C. Raghavan · 2010 · Journal of Nucleic Acids
Non-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways
Suzzette M. Arnal, Abigail J. Holub, Sandra S. Salus, David B. Roth · 2010 · Nucleic Acids Research
Fine-tuning CRISPR/Cas9 gene editing in common bean (Phaseolus vulgaris L.) using a hairy root transformation system and in silico prediction models
Ramon de Koning, Hana Daryanavard, Joyce Garmyn, R Kiekens, Mary Esther Muyoka Toili, Geert Angenon · 2023 · Frontiers in Plant Science
A Stochastic Model of DNA Fragments Rejoining
Yongfeng Li, Hong Qian, Ya Wang, Francis A. Cucinotta · 2012 · PLoS ONE
Metabolic Engineering of an Oleaginous Yeast for the Production of Omega-3 Fatty Acids
Quinn Zhu, Zhixiong Xue, Naren Yadav, Howard G. Damude, Dana Walters Pollak, Ross Rupert, John E. Seip, Dieter H. Hollerbach, Daniel Macool, Hongxiang Zhang et al. · 2010 · Elsevier eBooks
Advances in the biophysical and molecular bases of radiation cytogenetics
M.S. Sasaki · 2009 · International Journal of Radiation Biology
DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology
Rifaquat M. Rahman, Diana D. Shi, Zachary J. Reitman, Petra Hamerlik, John de Groot, Daphne Adele Haas-Kogan, Alan D. D’Andrea, Erik P. Sulman, Kirk G. Tanner, Nathalie Y.R. Agar et al. · 2024 · Neuro-Oncology
Involvement of the insulin-like growth factor binding proteins in the cancer cell response to DNA damage
Melissa W. Y. Chua, Mike Z. Lin, Janet L. Martin, Robert C. Baxter · 2015 · Journal of Cell Communication and Signaling
Regulation of Ceramide Synthase–Mediated Crypt Epithelium Apoptosis by DNA Damage Repair Enzymes
Jimmy A. Rotolo, Judith Mesicek, Jerzy Maj, Jean‐Philip Truman, Adriana Haimovitz‐Friedman, Richard Kolesnick, ZVI Y. FUKS · 2010 · Cancer Research
Sensitizing Ewing sarcoma to chemo- and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2
Britta Julia Vormoor, Yvonne T. Schlosser, Helen Blair, Abhishek Bharadwaj Sharma, Sarah Wilkinson, David R. Newell, Nicola J. Curtin · 2017 · Oncotarget
Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway
Tianze Liu, Lizi Jin, Miao Chen, Zongheng Zheng, Wenjing Lü, Wenhua Fan, Li Li, Fufu Zheng, Qiaohua Zhu, Huijuan Qiu et al. · 2019 · Redox Biology
Advances in PARP Inhibitors for Prostate Cancer
Steven Tisseverasinghe, Boris Bahoric, Maurice Anidjar, Stephan Probst, Tamim Mohammad Niazi · 2023 · Cancers
Single-molecule localization microscopy as a promising tool for γH2AX/53BP1 foci exploration
Daniel Depeš, Jin‐Ho Lee, Elizaveta Bobkova, Lucie Ježková, Iva Falková, Felix Bestvater, Eva Pagáčová, Olga Kopečná, M. G. Zadneprianetc, Alena Bačı́ková et al. · 2018 · The European Physical Journal D
Differential Requirement for SUB1 in Chromosomal and Plasmid Double-Strand DNA Break Repair
Lijian Yu, Michael R. Volkert · 2013 · PLoS ONE
Unveiling the mysteries of extrachromosomal circular DNA: from generation to clinical relevance in human cancers and health
Zilong Wang, Jiaying Yu, Wenli Zhu, Xiaoning Hong, Zhen Xu, Shuang Mao, Lei Huang, Peng Han, Chunxiao He, Changze Song et al. · 2024 · Molecular Cancer
Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery
Bohong Chen, Tianyu Ge, Meiqi Jian, Liutao Chen, Zhengwen Fang, Zibin He, Chengjing Huang, Yan An, Shanshan Yin, Yuanyan Xiong et al. · 2023 · Nature Cell Biology
Cells bearing chromosome aberrations lacking one telomere are selectively blocked at the G2/M checkpoint
P. Rodríguez, Joan Francesc Barquinero, Assumpta Duran, María Rosa Caballín, Montserrat Ribas, Leonardo Barrios · 2009 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
Protein acetylation within the cellular response to radiation
Nicole Averbeck, Marco Durante · 2010 · Journal of Cellular Physiology
Oxidative DNA Damage in Neurons: Implication of Ku in Neuronal Homeostasis and Survival
Daniela De Zio, Matteo Bordi, Francesco Cecconi · 2012 · International Journal of Cell Biology
Cell Lines Derived from a Medaka Radiation-Sensitive Mutant have Defects in DNA Double-Strand Break Responses
Masayuki Hidaka, Shoji Oda, Yoshikazu Kuwahara, Manabu Fukumoto, Hiroshi Mitani · 2010 · Journal of Radiation Research
Electron microscopy visualization of DNA–protein complexes formed by Ku and DNA ligase IV
Patricia Grob, Teri T. Zhang, Ryan Hannah, Hui Min Yang, Melissa L. Hefferin, Alan E. Tomkinson, Eva Nogales · 2011 · DNA repair
Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres
Carmen de Sena-Tomás, Eun Young Yu, Arturo Calzada, William K. Holloman, Neal F. Lue, José Pérez‐Martín · 2015 · Nucleic Acids Research
Role of DNA repair in the protection against genotoxic stress
Ulrike Camenisch, Hanspeter Naegeli · 2009 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
A Sir2-Like Protein Participates in Mycobacterial NHEJ
Zhongdao Li, Jikai Wen, Yaning Lin, Shihua Wang, Peng Xue, Zhiping Zhang, Ying Zhou, Xiao Wang, Li Sui, Lijun Bi et al. · 2011 · PLoS ONE
Ovarian Cancer: In Search of Better Marker Systems Based on DNA Repair Defects
Dominic Varga, Miriam Deniz, Lukas Schwentner, Lisa Wiesmüller · 2013 · International Journal of Molecular Sciences
Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis
Emil Mladenov, Janapriya Saha, George E. Iliakis · 2018 · Advances in experimental medicine and biology
Mitochondrial genome stability in human: understanding the role of DNA repair pathways
Sumedha Dahal, Sathees C. Raghavan · 2021 · Biochemical Journal
Acute oral mucositis in nasopharyngeal carcinoma patients treated with radiotherapy: Association with genetic polymorphism in DNA DSB repair genes
Jinghua Ren, Xiaofang Dai, Guo-Li Yan, Min Jin, Cui-Wei Liu, Kunyu Yang, Gang Wu, Chunmei Ma · 2013 · International Journal of Radiation Biology
Brh2 and Rad51 promote telomere maintenance in Ustilago maydis, a new model system of DNA repair proteins at telomeres
Eun Young Yu, Milorad Kojić, William K. Holloman, Neal F. Lue · 2013 · DNA repair
XRCC4 controls nuclear import and distribution of Ligase IV and exchanges faster at damaged DNA in complex with Ligase IV
Elke Berg, Morten O. Christensen, Ilaria Dalla Rosa, Ellen Wannagat, Reiner U. Jänicke, Lennart M. Rösner, Wilhelm Gerhard Dirks, Fritz Boege, Christian Mielke · 2011 · DNA repair
Polymorphisms in DNA repair genes in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome
Gloria Ravegnini, Margherita Nannini, Vittorio Simeon, Muriel Assunta Musti, Giulia Sammarini, Maristella Saponara, Lidia Gatto, Milena Urbini, Annalisa Astolfi, Guido Biasco et al. · 2016 · Tumor Biology
CREB-Binding Protein Regulates Ku70 Acetylation in Response to Ionization Radiation in Neuroblastoma
Chitra Subramanian, Manila Hada, Anthony W. Opipari, Valerie P. Castle, Roland P.S. Kwok · 2012 · Molecular Cancer Research
The role and clinical significance of DNA damage response and repair pathways in primary brain tumors
Wil L. Santivasi, Fen Xia · 2013 · Cell & Bioscience
ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition
Ali Bakr, Joschka Hey, Gianluca Sigismondo, Chun-Shan Liu, Ahmed Sadik, Ashish Goyal, Alice Cross, Ramya Lakshmana Iyer, Patrick Müller, Max Trauernicht et al. · 2021 · Nucleic Acids Research
Rrp47 and the function of the Sas10/C1D domain
Philip Mitchell · 2010 · Biochemical Society Transactions
ATM and DNA-PKcs make a complementary couple in DNA double strand break repair
Marta Martı́n, Mariona Terradas, Laura Tusell, Anna Genescà · 2012 · Mutation Research/Reviews in Mutation Research
Genotoxicity of topoisomerase II inhibitors: An anti-infective perspective
Daniel J. Smart · 2008 · Toxicology
Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response
Xiao-Feng Zheng, Peter Kalev, Dipanjan Chowdhury · 2015 · DNA repair
DNA-PK promotes the survival of young neurons in the embryonic mouse retina
Jimena Baleriola, Teresa Suárez, Enrique J. de la Rosa · 2010 · Cell Death and Differentiation
E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infection
Sumithra Jayaram, Timra D. Gilson, Elana S. Ehrlich, Xiao-Fang Yu, Gary W. Ketner, Les A. Hanakahi · 2008 · Virology
Hyperthermia Induces Apoptosis of 786-O Cells through Suppressing Ku80 Expression
Defeng Qi, Yuan Hu, Jinhui Li, Tao Peng, Jialin Su, Yun He, Weidong Ji · 2015 · PLoS ONE
Unraveling the future of genomics: CRISPR, single-cell omics, and the applications in cancer and immunology
A Vipin Menon, Bicna Song, Lumen Chao, Diksha Sriram, Pamela A. Chansky, Ishnoor Bakshi, Jane Ulianova, Wei Li · 2025 · Frontiers in Genome Editing
Effects of dna-Dependent Protein Kinase Inhibition by NU7026 on dna Repair and Cell Survival in Irradiated Gastric Cancer Cell Line N87
M.T. Niazi, G. Mok, Majid Momahed Heravi, L. Lee, T. Vuong, Raquel S. Aloyz, Lawrence Panasci, Thierry M. Muanza · 2014 · Current Oncology
Dual mTOR/DNA-PK Inhibitor CC-115 Induces Cell Death in Melanoma Cells and Has Radiosensitizing Potential
Felix Bürkel, Tina Jost, Markus Hecht, Lucie Heinzerling, Rainer Fietkau, Luitpold Valentin Distel · 2020 · International Journal of Molecular Sciences
Amniotic fluid stem cells in a bone microenvironment: Driving host angiogenic response
Teodelinda Mirabella, Chiara Gentili, Antonio Daga, Ranieri Cancedda · 2013 · Stem Cell Research
Chitooligomers inhibit UV-A-induced photoaging of skin by regulating TGF-β/Smad signaling cascade
Jung-Ae Kim, Byul‐Nim Ahn, Chang‐Suk Kong, Se‐Kwon Kim · 2011 · Carbohydrate Polymers
Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes
Jiali Zhuang, Zhiping Weng · 2015 · Nucleic Acids Research
Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB)
R. Nair, J. Kumar, Jedy Jose, V. Somasundaram, S. Hemalatha, S. Sengodan, R. Nadhan, T. Anilkumar, P. Srinivas · 2016 · Scientific Reports
The use of driving endonuclease genes to suppress mosquito vectors of malaria in temporally variable environments
Ben C. Lambert, Ace R. North, Austin Burt, H. Charles J. Godfray · 2018 · Malaria Journal