‘Remarkable’ AI tool designs mRNA vaccines that are more potent and stable
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In other settings, the same underlying AI technologies are used to advance medical drug discovery, including the development of Covid vaccines, enable real-time translation of spoken languages and provide free, customized tutoring to struggling learners and precocious autodidacts.
“In other settings, the same underlying AI technologies are used to advance medical drug discovery (including the development of Covid vaccines) (Qureshi et al., 2023;Dolgin, 2023), enable real-time translation of spoken languages and provide free, customized tutoring to struggling learners and precocious autodidacts.”
From Applying AI to Rebuild Middle Class Jobs (2024) · cites this paper as Dolgin, 2023
Cites
Algorithm for optimized mRNA design improves stability and immunogenicity
Zhang, H., Zhang, L., Lin, A., Xu, C., Li, Z., Liu, K., Liu, B., Ma, X., Zhao, F., Jiang, H., et al. (2023) · Nature · doi:10.1038/s41586-023-06127-z · Cited by 498 · see citing works
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
Leppek, K., Byeon, G. W., Kladwang, W., Wayment-Steele, H. K., Kerr, C. H., Xu, A. F., Kim, D. S., Topkar, V. V., Choe, C., Rothschild, D., et al. (2021) · doi:10.1101/2021.03.29.437587 · Cited by 399 · see citing works
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
Leppek, K., Byeon, G. W., Kladwang, W., Wayment-Steele, H. K., Kerr, C. H., Xu, A. F., Kim, D. S., Topkar, V. V., Choe, C., Rothschild, D., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28776-w · Cited by 399 · see citing works
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Applying AI to Rebuild Middle Class Jobs
Autor, D. (2024) · doi:10.3386/w32140 · Cited by 157 · see citing works
- Authors
- Dolgin, E.
- Corresponding author
- Dolgin, Elie
- Venue
- Nature
- Published
- 2023-05-02
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W4367672729
- Cited by
- 9
- References
- 3
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4
- Type
- other
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › vaccines and immunoinformatics approaches
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Keywords
- mRNA vaccine design, COVID-19 vaccines, antibody response, vaccine potency
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