Cited by 13Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic DiseasesObesity, Physical Activity, Diet

Effect of changes in waist circumference on metabolic syndrome over a 6.6-year follow-up in Tehran

Hosseinpanah, F, Barzin, M, Mirmiran, P, Azizi, F·2010·European Journal of Clinical Nutrition

Abstract

Background/objectives This cohort study was conducted to evaluate the effect of waist change on metabolic syndrome (MetS) status and its parameters in 5720 participants, aged >or=20 years, of the Tehran Lipid and Glucose Study who were followed up for a mean of 6.6 years.Subjects/methods We measured waist circumference (WC) and MetS parameters at baseline (phase I: 1999) and at follow-up (phase III: 2008), and assessed this relationship across five groups: waist loss (<-2.0 cm); waist stable (-2.0 to 2.9 cm); mild (3.0-5.9 cm); moderate (6.0-8.9 cm) and large (>or=9.0 cm) waist gain. MetS was defined according to the International Diabetes Federation criteria.Results In phase I, the mean (s.d.) waist gain was 88.8 cm (11.7). Between phases I and III, the mean (s.d.) waist gain was 5 cm (7.9). There was 16% (95% confidence interval (95% CI): 13.6-18.4) age-adjusted incident MetS and for every centimeter of WC gained over 6.6 years, the risk of MetS increased by 10% (odds ratio (OR) 1.10; 95% CI: 1.09-1.12). Compared with a stable WC in both genders, ORs for MetS for different waist gain groups were as follows: mild (OR 2.3, 95% CI: 1.7-3.2); moderate (OR 3.5, 95% CI: 2.6-4.7) and large (OR 5.8, 95% CI: 4.5-7.6). Waist loss had a protective effect on MetS (OR 0.6, 95% CI: 0.4-0.9). Waist gain showed a detrimental effect on all parameters of MetS in both genders, except for high-density lipoprotein cholesterol and fasting blood sugar in women.Conclusions Waist gain, even mild, was a risk factor of the development of MetS and its parameters. Intervention for reducing WC could be an effective strategy to decrease incident MetS.

Integrity signals

Registry

Crossref · 10.1038/ejcn.2010.79

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Hosseinpanah, F., Barzin, M., Mirmiran, P., & Azizi, F.
Affiliations
Research Institute for Endocrine Sciences (IR)
Corresponding author
Hosseinpanah, F
Venue
European Journal of Clinical Nutrition
Published
2010-05-19
Volume
64
Issue
8
Pages
879-886
ISSN
  • 0954-3007 (ISSN-L)
  • 1476-5640
OpenAlex
W2039088536
Cited by
13
References
31
Citations by year
2026: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2020: 2 · 2018: 3 · 2016: 1 · 2013: 1
FWCI
0.24
Type
journal article
Language
en
Open access
closed
Locations
  • European Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
waist circumference, metabolic syndrome, abdominal obesity, incident metabolic syndrome, risk factors, Tehran Lipid and Glucose Study, HDL cholesterol, fasting blood glucose
MeSH terms
Adult, Blood Glucose, Female, Follow-Up Studies, Humans, Iran, Cholesterol, HDL, Male, Middle Aged, Prospective Studies, Risk Factors, Sex Factors, Odds Ratio, Metabolic Syndrome, Waist Circumference, Obesity, Abdominal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review