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Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME‐4, a coated‐pit protein
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The study extended the known Retromer regulators to include DENND4A and DENND4C, TBC1D13, and a TBC1D1/TBC1D4 heterodimer, establishing mechanistic links between Retromer and the switching of RAB10 and RAB35.
“We have now extended these regulators to include DENND4A and DENND4C, TBC1D13, and a TBC1D1/TBC1D4 heterodimer, and in so doing, established mechanistic links between Retromer and the switching of RAB10 and RAB35; two RAB GTPases previously linked to the regulation of endosomal cargo recycling85,88–90,92,96,101,121,122.”
From Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation (2025) · cites this paper as [96]
RAB35 regulates endosomal exit for cell surface recycling, in part through controlling localised actin dynamics and phosphoinositide metabolism.
“RAB35 itself regulates endosomal exit for cell surface recycling95–99, in part through controlling localised actin dynamics and phosphoinositide metabolism100,101.”
From Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation (2025) · cites this paper as [96]
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Clathrin-independent pathways of endocytosis
Mayor, S., Parton, R. G., & Donaldson, J. G. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016758 · Cited by 525
LET-413/Erbin acts as a RAB-5 effector to promote RAB-10 activation during endocytic recycling
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Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation
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Metadata
- Authors
- Sato, M., Sato, K., Liou, W., Pant, S., Harada, A., & Grant, B. D.
- Venue
- The EMBO Journal
- Published
- 2008-03-20
- Volume
- 27
- Issue
- 8
- Pages
- 1183-1196
- ISSN
- 0261-4189
- 1460-2075
- Cited by
- 177
- References
- 2
- Language
- en
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