The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Pervasive transcription constitutes a new level of eukaryotic genome regulation
Open accessAbstract
During the past few years, it has become increasingly evident that the expression of eukaryotic genomes is far more complex than had been previously noted. The idea that the transcriptome is derived exclusively from protein‐coding genes and some specific non‐coding RNAs—such as snRNAs, snoRNAs, tRNAs or rRNAs—has been swept away by numerous studies indicating that RNA polymerase II can be found at almost any genomic location. Pervasive transcription is widespread and, far from being a futile process, has a crucial role in controlling gene expression and genomic plasticity. Here, we review recent findings that point to cryptic transcription as a fundamental component of the regulation of eukaryotic genomes.
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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
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Cited by
RNA sequencing: advances, challenges and opportunities
Ozsolak, F., & Milos, P. M. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2934 · Cited by 2,135
“We now have a new appreciation for the complexity of the transcriptome, encompassing a multitude of previously unknown coding and non-coding RNA species, particularly small RNAs (sRNAs), including microRNAs, promoter-associated RNAs and newly discovered antisense 3′ termini-associated RNA, to name a fe”
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Ting, D. T., Lipson, D., Paul, S., Brannigan, B. W., Akhavanfard, S., Coffman, E. J., Contino, G., Deshpande, V., Iafrate, A. J., Letovsky, S., et al. (2011) · Science · doi:10.1126/science.1200801 · Cited by 540
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Hu, W., Alvarez‐Dominguez, J. R., & Lodish, H. F. (2012) · EMBO reports · doi:10.1038/embor.2012.145 · Cited by 309
Chromatin and Transcription in Yeast
Rando, O. J., & Winston, F. (2012) · Genetics · doi:10.1534/genetics.111.132266 · Cited by 269
Rapid evolution of protein diversity by de novo origination in Oryza
Zhang, L., Ren, Y., Yang, T., Li, G., Chen, J., Gschwend, A. R., Yu, Y., Hou, G., Zi, J., Zhou, R., et al. (2019) · Nature Ecology & Evolution · doi:10.1038/s41559-019-0822-5 · Cited by 197
Metadata
- Authors
- Berretta, J., & Morillon, A.
- Venue
- EMBO reports
- Published
- 2009-08-14
- Volume
- 10
- Issue
- 9
- Pages
- 973-982
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- OpenAlex
- W2158722145
- Cited by
- 244
- References
- 3
- FWCI
- 8.64
- Type
- journal article
- Language
- en
- Open access
- green
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