Intraoperative optical coherence tomography: past, present, and future
Open accessAbstract
To provide an overview of the current state of intraoperative optical coherence tomography (OCT). Literature review of studies pertaining to intraoperative OCT examining both the technology aspects of the imaging platform and the current evidence for patient care. Over the last several years, there have been significant advances in integrative technology for intraoperative OCT. This has resulted in the development of multiple microscope-integrated systems and a rapidly expanding field of image-guided surgical care. Multiple studies have demonstrated the potential role for intraoperative OCT in facilitating surgeon understanding of the surgical environment, tissue configuration, and overall changes to anatomy. In fact, the PIONEER and DISCOVER studies, both demonstrated a potential significant percentage of cases that intraoperative OCT alters surgical decision-making in both anterior and posterior segment surgery. Current areas of exploration and development include OCT-compatible instrumentation, automated tracking, intraoperative OCT software platforms, and surgeon feedback/visualization platforms. Intraoperative OCT is an emerging technology that holds promise for enhancing the surgical care of both anterior segment and posterior segment conditions. Hurdles remain for adoption and widespread utilization, including cost, optimized feedback platforms, and more definitive value for individualized surgical care with image guidance.
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Despite intraoperative OCT, practical limitations include restricted OCT fields, shadowing of the operative site by intravitreal instruments, and inability for surgeons to operate and observe the iOCT image in real time.
“there are still practical limitations in iOCT systems including restricted OCT fields, shadowing of the operative site by intravitreal instruments and the inability for surgeons to operate and observe the iOCT image in real time.”
From Subretinal therapy: technological solutions to surgical and immunological challenges (2022) · cites this paper as [15]
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- Authors
- Ehlers, J. P.
- Affiliations
- Cleveland Clinic (US)
- Corresponding author
- Ehlers, J P
- ORCID
- Ehlers, J P
- Venue
- Eye
- Published
- 2015-12-18
- Volume
- 30
- Issue
- 2
- Pages
- 193-201
- ISSN
- 0078-5334 (ISSN-L)
- 0950-222X
- 1476-5454
- PMC
- PMC4763135
- OpenAlex
- W2204419648
- Cited by
- 77
- References
- 55
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 5 · 2023: 9 · 2022: 13 · 2021: 5 · 2020: 11 · 2019: 7 · 2018: 7 · 2017: 6 · 2016: 3
- FWCI
- 0.41
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Eye (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Research to Prevent Blindness
- Ohio Department of Development (TECH‐13‐059)
- National Institutes of Health (5k23ey022947-05, K23EY022947)
- National Eye Institute (K23-EY022947, K23 EY022947-01A1)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Optical Coherence Tomography Applications
- Health Sciences › Medicine › Ophthalmology › Intraocular Surgery and Lenses
- Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
- Keywords
- intraoperative optical coherence tomography, image-guided surgery, anterior segment surgery, posterior segment surgery, automatic tracking, surgical decision-making, ophthalmic surgery
- MeSH terms
- Diagnostic Techniques, Ophthalmological, Humans, Ophthalmologic Surgical Procedures, Monitoring, Intraoperative, Tomography, Optical Coherence
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