The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

Bessa, J M, Ferreira, D, Melo, I, Marques, F, Cerqueira, J J, Palha, J A, Almeida, O F X, Sousa, N·2009·Molecular Psychiatry

DOI 10.1038/mp.2008.119

Cited by (605)

Items 201–300 of 605

Conjoint and dissociated structural and functional abnormalities in first-episode drug-naive patients with major depressive disorder: a multimodal meta-analysis
Weina Wang, Youjin Zhao, Xinyu Hu, Xiaoqi Huang, Weihong Kuang, Su Lui, Graham John Kemp, Qiyong Gong · 2017 · Scientific Reports
P.2.d.023 Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress
Elisabeth Mocaër, Girstautė Dagytė, Ilaria Crescente, Folkert Postema, Laure Seguin, C. Gabriel, Johan A. den Boer, Jaap M. Koolhaas · 2011 · European Neuropsychopharmacology
Induction of the Wnt Antagonist Dickkopf-1 Is Involved in Stress-Induced Hippocampal Damage
Francesco Matrisciano, Carla Letizia Busceti, Domenico Bucci, Rosamaria Orlando, Alessandra Caruso, Gemma Molinaro, Irene Cappuccio, Barbara Riozzi, Roberto Gradini, Marta Motolese et al. · 2011 · PLoS ONE
Cannabinoid Modulation of the Stressed Hippocampus
Franciele Franco Scarante, Carla Vila-Verde, Vinícius Detoni Lopes, Nilson Carlos Ferreira‐Junior, Francisco Silveira Guimarães, Alline Cristina Campos · 2017 · Frontiers in Molecular Neuroscience
Positive mood-related gut microbiota in a long-term closed environment: a multiomics study based on the “Lunar Palace 365” experiment
Zikai Hao, Meng Chen, Leyuan Li, Siyuan Feng, Yinzhen Zhu, Jianlou Yang, Liangzhe Han, Leilei Sun, Weifeng Lv, Daniel Figeys et al. · 2023 · Microbiome
Ovarian hormones, but not fluoxetine, impart resilience within a chronic unpredictable stress model in middle-aged female rats
Rand Mahmoud, Steven R. Wainwright, Jessica A. Chaiton, Stephanie E. Lieblich, Liisa A.M. Galea · 2016 · Neuropharmacology
Corticosteroids: way upstream
Therese Riedemann, Alexandre V. Patchev, Kwangwook Cho, Osborne F. X. Almeida · 2010 · Molecular Brain
Environmental enrichment induces neuroplastic changes in middle age female BalbC mice and increases the hippocampal levels of BDNF, p-Akt and p-MAPK1/2
Gerardo Bernabé Ramírez-Rodríguez, María del Ángel Ocaña-Fernández, Nelly Maritza Vega‐Rivera, O.M. Torres-Pérez, Ariadna Gómez‐Sánchez, Erika Monserrat Estrada-Camarena, Laura I. Ortiz-López · 2013 · Neuroscience
Novel antidepressant effects of Paeonol alleviate neuronal injury with concomitant alterations in BDNF, Rac1 and RhoA levels in chronic unpredictable mild stress rats
Xiu-Ling Zhu, Jingjing Chen, Fei Han, Chuan Pan, Ting-Ting Zhuang, Yafei Cai, Ya-Ping Lu · 2018 · Psychopharmacology
Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields
Chrysoula Dioli, Patrícia Patrício, Nuno Sousa, Nikolaos Kokras, Christina Dalla, Sara R. Guerreiro, Miguel A. Santos-Silva, Ana Cristina Rego, Luísa Pinto, Elisabete B. Ferreiro et al. · 2019 · Translational Psychiatry
Do antidepressants promote neurogenesis in adult hippocampus? A systematic review and meta-analysis on naive rodents
Lino de Oliveira, Cilene, Bolzan, Juliana Aparecida, Surget, Alexandre, Belzung, Catherine · 2020 · Pharmacology & Therapeutics
Pharmacotherapy for anxiety disorders in children and adolescents
Kodish, Ian, Rockhill, Carol, Varley, Chris · 2011 · Dialogues in Clinical Neuroscience
Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder
Kellen C. Gandy, Sohye Kim, Carla Sharp, Lilian N. Dindo, Mirjana Maletić‐Savatić, Chadi Albert Calarge · 2017 · Frontiers in Neuroscience
Differential and Converging Molecular Mechanisms of Antidepressants’ Action in the Hippocampal Dentate Gyrus
Patrício, Patrícia, Mateus-Pinheiro, António, Irmler, Martin, Alves, Nuno D, Machado-Santos, Ana R, Morais, Mónica, Correia, Joana S, Korostynski, Michal, Piechota, Marcin, Stoffel, Rainer et al. · 2015 · Neuropsychopharmacology
Role of Adult Hippocampal Neurogenesis in Cognition in Physiology and Disease: Pharmacological Targets and Biomarkers
Veronica Costa, Sebastian Lugert, Ravi Jagasia · 2015 · Handbook of experimental pharmacology
Role of the Amygdala in Antidepressant Effects on Hippocampal Cell Proliferation and Survival and on Depression-like Behavior in the Rat
Jorge E. Castro, Emilio Varea, Cristina Márquez, Maria Isabel Cordero, Guillaume L. Poirier, Carmen Sandi · 2010 · PLoS ONE
Short day lengths alter stress and depressive-like responses, and hippocampal morphology in Siberian hamsters
Joanna L. Workman, Natalie Manny, James C. Walton, Randy J. Nelson · 2011 · Hormones and Behavior
Adult Hippocampal Neurogenesis in Depression: Behavioral Implications and Regulation by the Stress System
Christoph Anacker · 2014 · Current topics in behavioral neurosciences
Tet3 ablation in adult brain neurons increases anxiety-like behavior and regulates cognitive function in mice
Cláudia Antunes, Jorge Diogo Da Silva, Sónia Guerra‐Gomes, Nuno Dinis Alves, Fábio Ferreira, Eduardo Loureiro‐Campos, Miguel Ramos Branco, Nuno Sousa, Wolf Reik, Luísa Pinto et al. · 2020 · Molecular Psychiatry
Modulation of early stress-induced neurobiological changes: a review of behavioural and pharmacological interventions in animal models
Emma L. Harrison, Bernhard Theodor Baune · 2014 · Translational Psychiatry
Factors promoting vulnerability to dysregulated stress reactivity and stress‐related disease
Ashley L. Russell, Jeffrey G. Tasker, Aldo Bolten Lucion, Jenny Lucy Fiedler, Carolina Demarchi Munhoz, T. John Wu, Terrence Deak · 2018 · Journal of Neuroendocrinology
Voluntary running influences the efficacy of fluoxetine in a model of postpartum depression
Gobinath, Aarthi R., Richardson, Robin J., Chow, Carmen, Workman, Joanna L., Lieblich, Stephanie E., Barr, Alasdair M., Galea, Liisa A.M. · 2018 · Neuropharmacology
Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment
Diniz, Cassiano R.A.F., Casarotto, Plinio C, Resstel, Leonardo, Joca, Sâmia R.L. · 2018 · Neuroscience & Biobehavioral Reviews
Galanin mediates features of neural and behavioral stress resilience afforded by exercise
Sciolino, N.R., Smith, J.M., Stranahan, A.M., Freeman, K.G., Edwards, G.L., Weinshenker, D., Holmes, P.V. · 2015 · Neuropharmacology
The Neurotrophic Hypothesis of Depression Revisited: New Insights and Therapeutic Implications
Minal Jaggar, Sashaina E. Fanibunda, S K Ghosh, Ronald S. Duman, Vidita A. Vaidya · 2019 · Elsevier eBooks
Vagus nerve stimulation enhances perforant path-CA3 synaptic transmission via the activation of β-adrenergic receptors and the locus coeruleus
Huilian Shen, Yuta Fuchino, Daisuke Miyamoto, Hiroshi Nomura, Norio Matsuki · 2011 · The International Journal of Neuropsychopharmacology
Novel Insights into Depression and Antidepressants: A Synergy Between Synaptogenesis and Neurogenesis?
Francis Rodriguez Bambico, Catherine Belzung · 2012 · Current topics in behavioral neurosciences
Tau-dependent suppression of adult neurogenesis in the stressed hippocampus
Chrysoula Dioli, Patrícia Patrício, R. Trindade, Luísa Pinto, Joana Margarida Silva, Mónica Morais, Elisabete B. Ferreiro, Sónia Borges, António Mateus‐Pinheiro, Ana João Rodrigues et al. · 2017 · Molecular Psychiatry
Therapeutic Effect of Astroglia-like Mesenchymal Stem Cells Expressing Glutamate Transporter in a Genetic Rat Model of Depression
Amit Shwartz, Oshra Betzer, Noam Kronfeld, Gila Kazimirsky, Simona Cazacu, Susan Finniss, Hae Kyung Lee, Menachem Motiei, Shani Yael Dagan, Rachela Popovtzer et al. · 2017 · Theranostics
The modulation of adult neuroplasticity is involved in the mood-improving actions of atypical antipsychotics in an animal model of depression
Morais, M, Patrício, P, Mateus-Pinheiro, A, Alves, N D, Machado-Santos, A R, Correia, J S, Pereira, J, Pinto, L, Sousa, N, Bessa, J M · 2017 · Translational Psychiatry
Testosterone has antidepressant-like efficacy and facilitates imipramine-induced neuroplasticity in male rats exposed to chronic unpredictable stress
Steven R. Wainwright, Joanna L. Workman, Amir Rasooli Tehrani, Dwayne K. Hamson, Carmen Chow, Stephanie E. Lieblich, Liisa A.M. Galea · 2016 · Hormones and Behavior
Beyond negative valence: 2-week administration of a serotonergic antidepressant enhances both reward and effort learning signals
Scholl, Jacqueline, Kolling, Nils, Nelissen, Natalie, Browning, Michael, Rushworth, Matthew F. S., Harmer, Catherine J. · 2017 · PLOS Biology
How Stress Shapes Neuroimmune Function: Implications for the Neurobiology of Psychiatric Disorders
Ja Wook Koo, Eric S. Wohleb · 2020 · Biological Psychiatry
Acute and chronic stress differentially regulate cyclin-dependent kinase 5 in mouse brain: implications to glucocorticoid actions and major depression
Anna Papadopoulou, Thomas Siamatras, Raúl Delgado‐Morales, Niranjana D. Amin, Vineet Kumar Shukla, Y-L Zheng, Harish C. Pant, Osborne F. X. Almeida, Tomoshige Kino · 2015 · Translational Psychiatry
Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder
Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos da Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham D. Cocks, Danielle Beckman, Lucas Hosken, William de Sant’Anna Machado, Ana Carolina Corrêa-e-Castro et al. · 2014 · Behavioural Brain Research
Temporal Dynamics of Acute Stress-Induced Dendritic Remodeling in Medial Prefrontal Cortex and the Protective Effect of Desipramine
Nicoletta Nava, Giulia Treccani, Abdel‐Rahman Al‐Absi, Heidi Kaastrup Müller, Betina Elfving, Maurizio Popoli, Gregers Wegener, Jens Randel Nyengaard · 2015 · Cerebral Cortex
The adaptive and maladaptive continuum of stress responses – a hippocampal perspective
Deepika Suri, Vidita A. Vaidya · 2015 · Reviews in the Neurosciences
Chronic Fluoxetine Increases Extra-Hippocampal Neurogenesis in Adult Mice
Benjamin D. Sachs, Marc G. Caron · 2014 · The International Journal of Neuropsychopharmacology
Protein Kinase C Inhibition Rescues Manic-Like Behaviors and Hippocampal Cell Proliferation Deficits in the Sleep Deprivation Model of Mania
Erika Abrial, Alexandre Bétourné, Adeline Etiévant, Guillaume Lucas, Hélène Scarna, Laura Lambás‐Señas, Nasser Haddjeri · 2015 · The International Journal of Neuropsychopharmacology
Understanding the Role of Oxidative Stress, Neuroinflammation and Abnormal Myelination in Excessive Aggression Associated with Depression: Recent Input from Mechanistic Studies
Горлова Анна Вячеславовна, Evgeniy P. Svirin, Dmitrii Pavlov, Raymond Cespuglio, Andrey T. Proshin, Careen A. Schroeter, Klaus‐Peter Lesch, Tatyana V. Strekalova · 2023 · International Journal of Molecular Sciences
Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC
Nataly Ladurelle, C. Gabriel, Adela Viggiano, Elisabeth Mocaër, E.E. Baulieu, Massimiliano Bianchi · 2011 · Psychopharmacology
The effects of gestational stress and Selective Serotonin reuptake inhibitor antidepressant treatment on structural plasticity in the postpartum brain — A translational model for postpartum depression
Achikam Haim, Christopher Albin-Brooks, Morgan L. Sherer, Emily Mills, Benedetta Leuner · 2015 · Hormones and Behavior
Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABAA Receptor Expression in a Preclinical Model of Depression
Kyle J. Brymer, Erin Y. Fenton, Lisa E. Kalynchuk, Héctor J. Caruncho · 2018 · Frontiers in Pharmacology
Exploring the Potential Antidepressant Mechanisms of TNFα Antagonists
Kyle J. Brymer, Raquel Romay-Tallón, Josh Allen, Héctor J. Caruncho, Lisa E. Kalynchuk · 2019 · Frontiers in Neuroscience
Meta-analysis of brain structural changes after electroconvulsive therapy in depression
Gregor Gryglewski, Rupert R. Lanzenberger, L. Silberbauer, Daniel Pacher, Siegfried F. Kasper, Rainer Rupprecht, Richard Frey, P. Baldinger · 2021 · Brain stimulation
Drug withdrawal-induced depression: Serotonergic and plasticity changes in animal models
Thibault Renoir, Terence Y. Pang, Laurence Lanfumey · 2011 · Neuroscience & Biobehavioral Reviews
The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus
Gonzalo García‐Rojo, Cristóbal Fresno, Natalia Vilches, Gabriela Díaz‐Véliz, Sergio Mora, Felipe Ignacio Aguayo, Aníbal Pacheco, Nicolas A. Parra-Fiedler, Claudio S. Parra, Paulina S. Rojas et al. · 2016 · The International Journal of Neuropsychopharmacology
The Impact of Intermittent Fasting on Brain-Derived Neurotrophic Factor, Neurotrophin 3, and Rat Behavior in a Rat Model of Type 2 Diabetes Mellitus
Basem Hassan Elesawy, Bassem M. Raafat, Aya Al Muqbali, Amr Medhat Abbas, Hussein F. Sakr · 2021 · Brain Sciences
Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice
Sanghee Yun, Michael H. Donovan, Michele N. Ross, Devon R. Richardson, Robin Reister, Laure A. Farnbauch, Stephanie J. Fischer, Dieter Riethmacher, Howard K. Gershenfeld, Diane C. Lagace et al. · 2016 · PLoS ONE
JNK Regulation of Depression and Anxiety
Patrik Hollós, Francesca Marchisella, Eleanor T. Coffey · 2017 · Brain Plasticity
Stress Increases the Negative Effects of Chronic Pain on Hippocampal Neurogenesis
Carmen Romero‐Grimaldi, Esther Berrocoso, Cristina Alba‐Delgado, José L. M. Madrigal, Beatriz Gomez Perez‐Nievas, Juan Carlos Leza, Juan Antonio Micó · 2015 · Anesthesia & Analgesia
Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide
Marissa Maheu, Maria Antonietta Davoli, Gustavo Turecki, Naguib Mechawar · 2012 · Journal of Psychiatric Research
Escitalopram improves memory deficits induced by maternal separation in the rat.
F. Couto, V. Batalha, J. S. Valadas, João Data-Franca, J. Ribeiro, Luísa V. Lopes · 2012 · European Journal of Pharmacology
Chronic fluoxetine prevents fear memory generalization and enhances subsequent extinction by remodeling hippocampal dendritic spines and slowing down systems consolidation
Lizeth Katherine Pedraza, Rodrigo O. Sierra, Marcelo Giachero, Walquiria Souza Nunes, Fernanda Nogueira Lotz, Lucas de Oliveira Alvares · 2019 · Translational Psychiatry
Role of neurotrophic and growth factors in the rapid and sustained antidepressant actions of ketamine
Satoshi Deyama, Katsuyuki Kaneda · 2022 · Neuropharmacology
Pathophysiology of Mood Disorders in Temporal Lobe Epilepsy
Ludmyla Kandratavicius, Rafael Naime Ruggiero, Jaime E. C. Hallak, Norberto Garcia‐Cairasco, João Pereira Leite · 2012 · Brazilian Journal of Psychiatry
Modulation of Aversive Memory by Adult Hippocampal Neurogenesis
Michael R. Drew, Kylie A. Huckleberry · 2017 · Neurotherapeutics
Adult hippocampal neurogenesis: An actor in the antidepressant-like action
Indira Mendez‐David, René Hen, Alain Michel Gardier, Denis Joseph Paul David · 2013 · Annales Pharmaceutiques Françaises
The effects of congenital brain serotonin deficiency on responses to chronic fluoxetine
Benjamin D. Sachs, Jacob P. R. Jacobsen, Todne Thomas, William B. Siesser, Wendy L. Roberts, Marc G. Caron · 2013 · Translational Psychiatry
Potential animal models of seasonal affective disorder
Joanna L. Workman, Randy J. Nelson · 2010 · Neuroscience & Biobehavioral Reviews
PhenoWorld: a new paradigm to screen rodent behavior
Magda João Castelhano-Carlos, Patrício Costa, Holger Russig, Nuno Sousa · 2014 · Translational Psychiatry
Day and night: diurnal phase influences the response to chronic mild stress
Shilan Aslani, Mazen R. Harb, Patrício Costa, Osborne F. X. Almeida, Nuno Sousa, Joana Almeida Palha · 2014 · Frontiers in Behavioral Neuroscience
VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine
Jiang, Cheng, Lin, Wei-Jye, Labonté, Benoit, Tamminga, Carol A., Turecki, Gustavo, Nestler, Eric J., Russo, Scott J., Salton, Stephen R. · 2019 · Neuropsychopharmacology
A role for activity‐dependent epigenetics in the development and treatment of major depressive disorder
Corina Nagy, Kathryn Vaillancourt, Gustavo Turecki · 2017 · Genes Brain & Behavior
Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone
Gislaine Olescowicz, Vivian Binder Neis, Daiane B. Fraga, Priscila Batista da Rosa, Dayane Azevedo, Fernando Falkenburger Melleu, Patrícia S. Brocardo, Joana Gil‐Mohapel, Ana Lúcia S. Rodrigues · 2017 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
Fluoxetine Dose and Administration Method Differentially Affect Hippocampal Plasticity in Adult Female Rats
Jodi L. Pawluski, Eva L. van Donkelaar, Zipporah Abrams, Virginie Houbart, Marianne Fillet, Harry W.M. Steinbusch, Thierry D. Charlier · 2014 · Neural Plasticity
Fluoxetine attenuates the inhibitory effect of glucocorticoid hormones on neurogenesis in vitro via a two-pore domain potassium channel, TREK-1
Guangjun Xi, Xiangrong Zhang, Ling Zhang, Yuxiu Sui, Jiaojie Hui, Shanshan Liu, Yingxin Wang, Lingjiang Li, Zhijun Zhang · 2010 · Psychopharmacology
Curcumin prevents corticosterone‐induced neurotoxicity and abnormalities of neuroplasticity via 5‐HT receptor pathway
Ying Xu, Shan Li, Matthew M. Vernon, Jianchun Pan, Ling Chen, Philip A. Barish, Yuan Zhang, Abhinav P. Acharya, Jie Zhong Yu, Subramaniam S. Govindarajan et al. · 2011 · Journal of Neurochemistry
Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review
Siu Wa Tang, Daiga Maret Helmeste, Brian E. Leonard · 2011 · The World Journal of Biological Psychiatry
Reelin-Related Disturbances in Depression: Implications for Translational Studies
Héctor J. Caruncho, Kyle J. Brymer, Raquel Romay-Tallón, Milann A. Mitchell, Tania Rivera Baltanás, Justin J. Botterill, José Manuel Olivares, Lisa E. Kalynchuk · 2016 · Frontiers in Cellular Neuroscience
Sertraline behavioral response associates closer and dose-dependently with cortical rather than hippocampal serotonergic activity in the rat forced swim stress
Hudu Garba Mikail, Christina Dalla, Nikolaos Kokras, Vasilios Kafetzopoulos, Zeta Papadopoulou‐Daifoti · 2012 · Physiology & Behavior
Female Hippocampus Vulnerability to Environmental Stress, a Precipitating Factor in Tau Aggregation Pathology
Ioannis Sotiropoulos, Joana Margarida Silva, Tetsuya Kimura, Ana João Rodrigues, Patrício Costa, Osborne F. X. Almeida, Nuno Sousa, Akihiko Takashima · 2014 · Journal of Alzheimer s Disease
Antistress properties of antidepressant drugs and their clinical implications
Francesca Calabrese, Raffaella Molteni, Marco Andrea Riva · 2011 · Pharmacology & Therapeutics
Antidepressant-Like Effects of Erythropoietin: A Focus on Behavioural and Hippocampal Processes
Meagan Osborn, Nazneen Rustom, Melanie Clarke, Darcy Litteljohn, Chris Rudyk, Hymie Anisman, Shawn P. Hayley · 2013 · PLoS ONE
Reciprocal interactions across and within multiple levels of monoamine and cortico-limbic systems in stress-induced depression: A systematic review
Eun Hwa Lee, Pyung‐Lim Han · 2019 · Neuroscience & Biobehavioral Reviews
Plasticity of synapses and reward circuit function in the genesis and treatment of depression
Thompson, Scott M. · 2023 · Neuropsychopharmacology
The positive effect on ketamine as a priming adjuvant in antidepressant treatment
António Melo, Nikolaos Kokras, Christina Dalla, Clara Ferreira, Ana Paula Ventura‐Silva, Nuno Sousa, José Miguel Pêgo · 2015 · Translational Psychiatry
Melatonin synergizes with citalopram to induce antidepressant‐like behavior and to promote hippocampal neurogenesis in adult mice
Gerardo Bernabé Ramírez-Rodríguez, Nelly Maritza Vega‐Rivera, Julián Oikawa‐Sala, Ariadna Gómez‐Sánchez, Leonardo Ortíz‐López, Erika Monserrat Estrada-Camarena · 2014 · Journal of Pineal Research
Epigenetics of Depression
Sermsak Lolak, Pim Suwannarat, Robert H. Lipsky · 2014 · Progress in molecular biology and translational science
Resilience to stress and sex-specific remodeling of microglia and neuronal morphology in a rat model of anxiety and anhedonia
Rita Gaspar, Carina Soares‐Cunha, Ana Verónica Domingues, Bárbara Coimbra, Filipa I. Baptista, Luísa Pinto, António Francisco Ambrósio, Ana João Rodrigues, Catarina A. Gomes · 2021 · Neurobiology of Stress
Retardation of neurobehavioral development and reelin down-regulation regulated by further DNA methylation in the hippocampus of the rat pups are associated with maternal deprivation
Lina Qin, Wen-Qiang Tu, Xiu-Min Sun, Jianlong Zhang, Yuchuan Chen, Hu Zhao · 2010 · Behavioural Brain Research
Prior high corticosterone exposure reduces activation of immature neurons in the ventral hippocampus in response to spatial and nonspatial memory
Joanna L. Workman, Melissa Y.T. Chan, Liisa A.M. Galea · 2014 · Hippocampus
Melatonin Reverses the Depression-associated Behaviour and Regulates Microglia, Fractalkine Expression and Neurogenesis in Adult Mice Exposed to Chronic Mild Stress
Nelly Maritza Vega‐Rivera, Leonardo Ortíz‐López, Andrea Granados-Juárez, Erika Monserrat Estrada-Camarena, Gerardo Bernabé Ramírez-Rodríguez · 2020 · Neuroscience
PTEN in prefrontal cortex is essential in regulating depression-like behaviors in mice
Xiao-Qing Wang, Lei Zhang, Zhongyuan Xia, Jia‐Yin Chen, Yiru Fang, Yu‐Qiang Ding · 2021 · Translational Psychiatry
Re-cycling Paradigms: Cell Cycle Regulation in Adult Hippocampal Neurogenesis and Implications for Depression
Patrícia Patrício, António Mateus‐Pinheiro, Nuno Sousa, Luísa Pinto · 2013 · Molecular Neurobiology
AP2γ controls adult hippocampal neurogenesis and modulates cognitive, but not anxiety or depressive-like behavior
António Mateus‐Pinheiro, Nuno Dinis Alves, Patrícia Patrício, Ana Rita Machado-Santos, Eduardo Loureiro‐Campos, Joana Margarida Silva, Vanessa Morais Sardinha, Joana Santos Reis, Hubert Schorle, João Filipe Oliveira et al. · 2016 · Molecular Psychiatry
Conditional reduction of adult born doublecortin-positive neurons reversibly impairs selective behaviors
Garrett, Lillian, Zhang, Jingzhong, Zimprich, Annemarie, Niedermeier, Kristina M., Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Vogt Weisenhorn, Daniela, Wurst, Wolfgang, Hölter, Sabine M. · 2015 · Frontiers in Behavioral Neuroscience
Effect of Acute Stress on the Expression of BDNF, trkB, and PSA-NCAM in the Hippocampus of the Roman Rats: A Genetic Model of Vulnerability/Resistance to Stress-Induced Depression
Maria Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, Maria Antonietta Piludu, Fabrizio Sanna, Maria Giuseppa Corda, Osvaldo Giorgi, Marina Quartu · 2018 · International Journal of Molecular Sciences
Fluoxetine induces input-specific hippocampal dendritic spine remodeling along the septotemporal axis in adulthood and middle age
McAvoy, Kathleen, Russo, Craig, Kim, Shannen, Rankin, Genelle, Sahay, Amar · 2015 · Hippocampus
Studies of Long-Term Use of Antidepressants: How Should the Data from Them be Interpreted?
El-Mallakh, Rif S., Briscoe, Brian · 2012 · CNS Drugs
In vitroandin vivoregulation of synaptogenesis by the novel antidepressant spadin
Christelle Devader, Anouar Khayachi, J. Veyssière, Hamid Moha ou Maati, Morgane Roulot, Sébastien Moréno, Marc Borsotto, S Martin, Catherine Heurteaux, Jean Mazella · 2015 · British Journal of Pharmacology
Acute antidepressant treatment differently modulates ERK/MAPK activation in neurons and astrocytes of the adult mouse prefrontal cortex
Barbara Di Benedetto, Julika Radecke, Mathias V. Schmidt, Rainer Rupprecht · 2012 · Neuroscience
Chronic stress targets adult neurogenesis preferentially in the suprapyramidal blade of the rat dorsal dentate gyrus
Nuno Dinis Alves, Patrícia Patrício, Joana Sofia Correia, António Mateus‐Pinheiro, Ana Rita Machado-Santos, Eduardo Loureiro‐Campos, Mónica Morais, João Miguel Bessa, Nuno Sousa, Luísa Pinto · 2017 · Brain Structure and Function
The dentate gyrus in depression
Gali Umschweif, Paul Greengard, Yotam Sagi · 2019 · European Journal of Neuroscience
The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation
Luis E.B. Bettio, Vivian Binder Neis, Francis L. Pazini, Patrícia S. Brocardo, Anna R. Patten, Joana Gil‐Mohapel, Brian R. Christie, Ana Lúcia S. Rodrigues · 2016 · European Journal of Neuroscience
Piromelatine ameliorates memory deficits associated with chronic mild stress-induced anhedonia in rats
Wan Fu, Heng Xie, Moshe Laudon, Shouhong Zhou, Shaowen Tian, Yong You · 2016 · Psychopharmacology
Temporal modulation of hippocampal excitatory transmission by corticosteroids and stress
Francis Chaouloff, Laurent Groc · 2010 · Frontiers in Neuroendocrinology
Therapeutic Modalities for Treatment Resistant Depression: Focus on Vagal Nerve Stimulation and Ketamine
Aparna P. Shah, Flavia Regina Carreno, Alan Frazer · 2014 · Clinical Psychopharmacology and Neuroscience
Recent insights into antidepressant therapy: Distinct pathways and potential common mechanisms in the treatment of depressive syndromes
Dietrich van Calker, Tsvetan Serchov, Claus Normann, Knut P. H. Biber · 2018 · Neuroscience & Biobehavioral Reviews
Brain entropy and neurotrophic molecular markers accompanying clinical improvement after ketamine: Preliminary evidence in adolescents with treatment-resistant depression
Abhrajeet V. Roy, Michelle Thai, Bonnie Klimes‐Dougan, Mindy Westlund Schreiner, Bryon A. Mueller, Christina Sophia Albott, Kelvin O. Lim, Mark Joseph A. Fiecas, Susannah J. Tye, Kathryn Regan Cullen · 2020 · Journal of Psychopharmacology