Almeida, Osborne F. X.

Dynamic DNA methylation programs persistent adverse effects of early-life stress

Murgatroyd, C., Patchev, A. V., Wu, Y., Micale, V., Bockmühl, Y., Fischer, D., Holsboer, F., Wotjak, C. T., Almeida, O. F. X., & Spengler, D. (2009) · Nature Neuroscience

Epigenetics and DNA MethylationStress Responses and Cortisol

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Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement

Sousa, N., Lukoyanov, N. V., Madeira, M. D., Almeida, O. F. X., & Paula-Barbosa, M. M. (2000) · Neuroscience

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 758

The prefrontal cortex as a key target of the maladaptive response to stress

Cerqueira, J. J., Mailliet, F., Almeida, O. F. X., Jay, T. M., & Sousa, N. (2007) · The Journal of Neuroscience

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 599

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

Bessa, J. M., Ferreira, D., Melo, I., Marques, F., Cerqueira, J. J., Palha, J. A., Almeida, O. F. X., & Sousa, N. (2009) · Molecular Psychiatry

Treatment of Major DepressionNeurogenesis and neuroplasticity mechanisms

Cited by 598

Chronic stress and glucocorticoids: From neuronal plasticity to neurodegeneration

Vyas, S., Rodrigues, A. J., Silva, J. M., Tronche, F., Almeida, O. F. X., Sousa, N., & Sotiropoulos, I. (2016) · Neural Plasticity

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 297

Selective inhibitors of the FK506-binding protein 51 by induced fit

Gaali, S., Kirschner, A., Cuboni, S., Hartmann, J., Kozany, C., Balsevich, G., Namendorf, C., Fernandez-Vizarra, P., Sippel, C., Zannas, A. S., et al. (2015) · Nature Chemical Biology

Signaling Pathways in DiseaseTreatment of Major Depression

Cited by 245

Disconnection and reconnection: The morphological basis of (mal)adaptation to stress

Sousa, N., & Almeida, O. F. X. (2012) · Trends in Neurosciences

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 159

Sustained remission from depressive-like behavior depends on hippocampal neurogenesis

Mateus-Pinheiro, A., Pinto, L., Bessa, J. M., Morais, M., Alves, N. D., Monteiro, S., Patrício, P., Almeida, O. F. X., & Sousa, N. (2013) · Translational Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 149

Early-Life Stress Reduces DNA Methylation of the Pomc Gene in Male Mice

Wu, Y., Patchev, A. V., Daniel, G., Almeida, O. F. X., & Spengler, D. (2014) · Endocrinology

Stress Responses and CortisolEpigenetics and DNA Methylation

Cited by 142

Stimulation of hypothalamic β-endorphin and dynorphin release by corticotropin-releasing factor (in vitro)

Nikolarakis, K. E., Almeida, O. F. X., & Herz, A. (1986) · Brain Research

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 136

Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens

Bessa, J. M., Morais, M., Marques, F., Pinto, L., Palha, J. A., Almeida, O. F. X., & Sousa, N. (2013) · Translational Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 130

Potential programming of dopaminergic circuits by early life stress

Rodrigues, A.-J., Leão, P., Carvalho, M., Almeida, O. F. X., & Sousa, N. (2011) · Psychopharmacology

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

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Glucocorticoids Trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau

Sotiropoulos, I., Catania, C., Riedemann, T., Fry, J. P., Breen, K. C., Michaelidis, T. M., & Almeida, O. F. X. (2008) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 97

Oxytocin-stimulated release of adrenocorticotropin from the rat pituitary is mediated by arginine vasopressin receptors of the V1b type

Schlosser, S. F., Almeida, O. F., Patchev, V. K., Yassouridis, A., & Elands, J. (1994) · Endocrinology

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 75

Tau Deletion Prevents Stress-Induced Dendritic Atrophy in Prefrontal Cortex: Role of Synaptic Mitochondria

Lopes, S., Teplytska, L., Vaz-Silva, J., Dioli, C., Trindade, R., Morais, M., Webhofer, C., Maccarrone, G., Almeida, O. F. X., Turck, C. W., et al. (2016) · Cerebral Cortex

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

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Differential and Converging Molecular Mechanisms of Antidepressants’ Action in the Hippocampal Dentate Gyrus

Patrício, P., Mateus-Pinheiro, A., Irmler, M., Alves, N. D., Machado-Santos, A. R., Morais, M., Correia, J. S., Korostynski, M., Piechota, M., Stoffel, R., et al. (2015) · Neuropsychopharmacology

Treatment of Major DepressionStress Responses and Cortisol

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Hippocampal neurogenesis induced by antidepressant drugs: an epiphenomenon in their mood-improving actions

Bessa, J. M., Ferreira, D., Melo, I., Marques, F., Cerqueira, J. J., Palha, J. A., Almeida, O. F. X., & Sousa, N. (2009) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

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