De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
Kirov, G, Pocklington, A J, Holmans, P, Ivanov, D, Ikeda, M, Ruderfer, D, Moran, J, Chambert, K +22 more·2012·Molecular Psychiatry
Cited by (879)
Items 301–400 of 879
- Endophenotypes in Schizophrenia: Digging Deeper to Identify Genetic MechanismsTiffany A. Greenwood, Andrew Shutes‐David, Debby W. Tsuang · 2019 · Journal of Psychiatry and Brain Science
- Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase GeneJ. Alexander Bodkin, Michael J. Coleman, Laura Godfrey, Claudia M.B. Carvalho, Charity Johanna Morgan, Raymond F. Suckow, Thea Anderson, Döst Öngür, Marc J. Kaufman, Kathryn E. Lewandowski et al. · 2019 · Biological Psychiatry
- A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their functionMenglong Zeng, Yuan Shang, Tingfeng Guo, Qinghai He, Wing‐Ho Yung, Kai Liu, Mingjie Zhang · 2016 · Proceedings of the National Academy of Sciences
- Schizophrenia: Basic and ClinicalJoseph T. Coyle · 2017 · Advances in neurobiology
- Mechanistic insights into the genetics of affective psychosis from Prader-Willi syndromeAman, Lucie C S, Manning, Katherine E, Whittington, Joyce E, Holland, Anthony J · 2018 · The Lancet Psychiatry
- Euchromatin histone methyltransferase 1 regulates cortical neuronal network developmentMarijn Bart Martens, Monica Frega, Jessica Classen, Lisa Epping, Elske Bijvank, Marco Benevento, Hans van Bokhoven, Paul H. E. Tiesinga, Dirk Schubert, Nael Nadif Kasri · 2016 · Scientific Reports
- Psychosis spectrum illnesses as disorders of prefrontal critical period plasticitySophia Vinogradov, Matthew V. Chafee, Erik G. Lee, Hirofumi Morishita · 2022 · Neuropsychopharmacology
- JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia riskRebecca L. Openshaw, Jaedeok Kwon, Alison McColl, Josef Martin Penninger, Jonathan Cavanagh, Judith A. Pratt, BRIAN J. MORRIS · 2019 · Journal of Neuroinflammation
- Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune ChallengeDianelys González-Peña, Scott E. Nixon, Jason C. O’Connor, Bruce R. Southey, Marcus A. Lawson, Robert H. McCusker, Tania Borras, Debbie Machuca, Álvaro González Hernández, Robert Dantzer et al. · 2016 · PLoS ONE
- Altered Expression of ARP2/3 Complex Signaling Pathway Genes in Prefrontal Layer 3 Pyramidal Cells in SchizophreniaDibyadeep Datta, Dominique Arion, Kaitlyn M. Roman, David W. Volk, David A. Lewis · 2016 · American Journal of Psychiatry
- From De Novo Mutations to Personalized Therapeutic Interventions in AutismWilliam M. Brandler, Jonathan L. Sebat · 2015 · Annual Review of Medicine
- Immediate Early Genes Anchor a Biological Pathway of Proteins Required for Memory Formation, Long-Term Depression and Risk for SchizophreniaKetan K. Marballi, Amelia L. Gallitano · 2018 · Frontiers in Behavioral Neuroscience
- Role of the DLGAP2 Gene Encoding the SAP90/PSD-95-Associated Protein 2 in SchizophreniaJunming Li, Chao-Lin Lu, Min-Chih Cheng, Sy-Ueng Luu, Shih-Hsin Hsu, Tsung‐Ming Hu, Hsin-Yao Tsai, Chia‐Hsiang Chen · 2014 · PLoS ONE
- Analysis of exome sequence in 604 trios for recessive genotypes in schizophreniaElliott Rees, George Kirov, James Walters, Alexander L. Richards, Daniel P. Howrigan, David H. Kavanagh, Andrew J. Pocklington, Menachem Fromer, Douglas M. Ruderfer, L. Georgieva et al. · 2015 · Translational Psychiatry
- NGL-2 Deletion Leads to Autistic-like Behaviors Responsive to NMDAR ModulationSeung Min Um, Seungmin Ha, Hyejin Lee, Jihye Kim, Kyungdeok Kim, Wangyong Shin, Yi Sul Cho, Junyeop Daniel Roh, Jaeseung Kang, Taesun Yoo et al. · 2018 · Cell Reports
- Common and Rare Genetic Risk Factors Converge in Protein Interaction Networks Underlying SchizophreniaXiao Chang, Leandro de A. Lima, Yichuan Liu, Jin Li, Qingqin S. Li, Patrick M. Abou‐Sleiman, Hakon H. Hakonarson · 2018 · Frontiers in Genetics
- New discoveries in schizophrenia genetics reveal neurobiological pathways: A review of recent findingsAlex Kotlar, Kristina B. Mercer, Michael E. Zwick, Jennifer G. Mullé · 2015 · European Journal of Medical Genetics
- Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunctionDarrick T. Balu, Joseph T. Coyle · 2014 · Neurochemistry International
- Monkey Prefrontal Neurons Reflect Logical Operations for Cognitive Control in a Variant of the AX Continuous Performance Task (AX-CPT)Rachael Keir Blackman, David A. Crowe, Adele L. DeNicola, Sofia Sakellaridi, Angus W. MacDonald, Matthew V. Chafee · 2016 · Journal of Neuroscience
- Genetics of schizophrenia (Review)Simona Corina Trifu, Bianca Kohn, Andrei Vlasie, B.E. Patrichi · 2020 · Experimental and Therapeutic Medicine
- mGluR5 Ablation in Cortical Glutamatergic Neurons Increases Novelty-Induced LocomotionChris P. Jew, Chia‐Shan Wu, Hao Sun, Jie Zhu, Jui-Yen Huang, Dinghui Yu, Nicholas J. Justice, Hui‐Chen Lu · 2013 · PLoS ONE
- Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: A unique window into the origins of ScZ?Judith A. Pratt, Neil Dawson, Brain J. Morris, Tineke Grent-‘t-Jong, Frédéric Roux, Peter J. Uhlhaas · 2016 · Schizophrenia Research
- Sleep Disturbance as a Precursor of Severe Regression in Kleefstra Syndrome Suggests a Need for Firm and Rapid Pharmacological TreatmentKarlijn Vermeulen, Wouter Staal, Joost Janzing, Hans van Bokhoven, J.I.M. Egger, Tjitske Kleefstra · 2017 · Clinical Neuropharmacology
- Top-Down Suppression of Sensory Cortex in an NMDAR Hypofunction Model of PsychosisAdam Ranson, Eluned Broom, Anna L. Powell, Fangli Chen, Guy Major, Jérémy Hall · 2019 · Schizophrenia Bulletin
- A critical review of zebrafish schizophrenia models: Time for validation?Kinga Gaweł, Nancy Saana Banono, Agnieszka Michalak, Camila Vicencio Esguerra · 2019 · Neuroscience & Biobehavioral Reviews
- Novel promoters and coding first exons in DLG2 linked to developmental disorders and intellectual disabilityClaudio Reggiani, Sandra Coppens, Tayeb Sékhara, Ivan Dimov, Bruno Pichon, Nicolas Lufin, Marie‐Claude Addor, Elga Fabia Belligni, Maria Cristina Digilio, Flavio Faletra et al. · 2017 · Genome Medicine
- Systematic Prioritization and Integrative Analysis of Copy Number Variations in Schizophrenia Reveal Key Schizophrenia Susceptibility GenesXiong‐Jian Luo, Liang Huang, Leng Han, Zhenwu Luo, Fang Hu, Roger Tieu, Lin Gan · 2014 · Schizophrenia Bulletin
- From the periphery to centre stage: de novo single nucleotide variants play a key role in human genetic diseaseChee‐Seng Ku, Eng King Tan, D.N. Cooper · 2013 · Journal of Medical Genetics
- Activity‐regulated cytoskeleton‐associated protein (Arc/Arg3.1) regulates anxiety‐ and novelty‐related behaviorsRachel D. Penrod, Jaswinder Kumar, Laura N. Smith, Daniel M. McCalley, Todd B. Nentwig, Brandon W. Hughes, Gabriella M. Barry, Kelsey Glover, Makoto Taniguchi, Christopher W. Cowan · 2019 · Genes Brain & Behavior
- Functional impairment of cortical AMPA receptors in schizophreniaTommaso Zeppillo, Anton Schulmann, Fabio M. Macciardi, Brooke E. Hjelm, Melanie Föcking, P. Adolfo Sequeira, Ilaria Guella, David Cotter, William E. Bunney, Agenor Limón et al. · 2020 · Schizophrenia Research
- A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatumTaesun Yoo, Sun-Gyun Kim, Soo Hyun Yang, Hyun Kim, Eunjoon Kim, Soo Young Kim · 2020 · Molecular Autism
- Rare copy number variants in neuropsychiatric disorders: Specific phenotype or not?Maarten J. A. Van Den Bossche, Mandy Johnstone, Mojca Stražišar, Ben S. Pickard, Dirk Goossens, An‐Sofie Lenaerts, Sonia De Zutter, Annelie Nordin, Karl‐Fredrik Norrback, Julien Mendlewicz et al. · 2012 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Neuropsychological phenotype of a patient with a de novo 970 kb interstitial deletion in the distal 16p11.2 regionJ.I.M. Egger, Willem M. A. Verhoeven, Wim Verbeeck, Nicole de Leeuw · 2014 · Neuropsychiatric Disease and Treatment
- The variation game: Cracking complex genetic disorders with NGS and omics dataHongzhu Cui, Andi Dhroso, Nathan T. Johnson, Dmitry Korkin · 2015 · Methods
- Targeted next generation sequencing of a panel of autism-related genes identifies an EHMT1 mutation in a Kleefstra syndrome patient with autism and normal intellectual performanceIstván Bock, Krisztina Németh, Klára Pentelényi, Péter Balicza, Anna Balázs, Mária Judit Molnár, Viktor Román, József Nagy, György I. Lévay, Julianna Kobolák et al. · 2016 · Gene
- Impact of IQ on the diagnostic yield of chromosomal microarray in a community sample of adults with schizophreniaChelsea Lowther, Daniele Merico, Gregory Costain, Jack Waserman, Kerry Boyd, Abdul Noor, Marsha D. Speevak, Dimitri James Stavropoulos, John Wei, Anath Christopher Lionel et al. · 2017 · Genome Medicine
- Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signalingDick Schijven, Daniel Kofink, Vinicius Tragante, Marloes Verkerke, Sara L. Pulit, René S. Kahn, Jan Herman Veldink, Christiaan H. Vinkers, Marco P. Boks, Jurjen Justin Luykx · 2018 · Schizophrenia Research
- Neural and behavioral epigenetics; what it is, and what is hypeAnthony R Isles · 2014 · Genes Brain & Behavior
- Next‐generation sequencing in schizophrenia and other neuropsychiatric disordersMatthew A. Schreiber, Michael O. Dorschner, Debby W. Tsuang · 2013 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Distribution of Disease-Associated Copy Number Variants Across Distinct Disorders of Cognitive DevelopmentMatthew F. Pescosolido, Ece Dilber Gamsiz Uzun, Shailender Nagpal, Eric M. Morrow · 2013 · Journal of the American Academy of Child & Adolescent Psychiatry
- The regulatory effects of lactic acid on neuropsychiatric disordersXueyi Chen, Yangdong Zhang, Haiyang Wang, Lanxiang Liu, Wenwen Li, Peng Ping Xie · 2022 · Discover Mental Health
- Genomics of schizophrenia, bipolar disorder and major depressive disorderMichael John Owen, Nicholas J. Bray, James Walters, Michael C. O’Donovan · 2025 · Nature Reviews Genetics
- Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of SchizophreniaDibyadeep Datta, Amy F.T. Arnsten · 2018 · ACS Chemical Neuroscience
- Genetic studies of schizophrenia: an updateJingchun Chen, Fei Cao, Lanfen Liu, Lina Wang, Xiangning Chen · 2015 · Neuroscience Bulletin
- Arc ubiquitination in synaptic plasticityAngela M. Mabb, Michael Ehlers · 2017 · Seminars in Cell and Developmental Biology
- Marker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypesChristopher M. Grochowski, Shen Gu, Bo Yuan, Julia TCW, Kristen Brennand, Jonathan L. Sebat, Dheeraj Malhotra, Shane McCarthy, Uwe Rudolph, Anna Lindstrand et al. · 2018 · Human Mutation
- De novo variation in bipolar disorderFernando S. Goes, Mehdi Pirooznia, Martin Tehan, Peter P. Zandi, John A. McGrath, Paula S Wolyniec, Gerald Nestadt, Ann E. Pulver · 2019 · Molecular Psychiatry
- Cognitive components in mice and humans: Combining genetics and touchscreens for medical translationJess Nithianantharajah, Seth G. N. Grant · 2013 · Neurobiology of Learning and Memory
- Synaptic structural protein dysfunction leads to altered excitation inhibition ratios in models of autism spectrum disorderHowell, Brian W., Smith, Kathleen M. · 2019 · Pharmacological Research
- The epigenome and postnatal environmental influences in psychotic disordersEhsan Pishva, Günter Kenis, Daniël van den Hove, Klaus‐Peter Lesch, Marco P. Boks, Jim van Os, Bart P. F. Rutten · 2014 · Social Psychiatry and Psychiatric Epidemiology
- Differential expression of DLG1 as a common trait in different human diseases: an encouraging issue in molecular pathologyFederico Marziali, Marìa Paula Dizanzo, Ana Laura Cavatorta, Daniela Gardiol · 2018 · Biological Chemistry
- Identification of a CACNA2D4 deletion in late onset bipolar disorder patients and implications for the involvement of voltage‐dependent calcium channels in psychiatric disordersMaarten J. A. Van Den Bossche, Mojca Stražišar, Stephan De Bruyne, Chris Bervoets, An‐Sofie Lenaerts, Sonia De Zutter, Annelie Nordin, Karl‐Fredrik Norrback, Dirk Goossens, Peter De Rijk et al. · 2012 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Caveolin-1 regulation ofdisrupted-in-schizophrenia-1 as a potential therapeutic target for schizophreniaAdam Kassan, Junji Egawa, Zheng Zhang, Angels Almenar‐Queralt, Quynh My Nguyen, Yasaman Lajevardi, Kaitlyn Kim, Edmund Posadas, Dilip V. Jeste, David M. Roth et al. · 2016 · Journal of Neurophysiology
- Challenges and opportunities for the development of new antipsychotic drugsCarlos Forray, R. Buller · 2017 · Biochemical Pharmacology
- Association of copy number variation across the genome with neuropsychiatric traits in the general populationAnna L. Guyatt, Evie Stergiakouli, Joanna Martin, James Walters, Michael C. O’Donovan, Michael John Owen, Anita Thapar, George Kirov, Santiago Rodrı́guez, Dheeraj Rai et al. · 2018 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Identification of RELN variation p.Thr3192Ser in a Chinese family with schizophreniaZhifan Zhou, Zhengmao Hu, Lu Zhang, Zhaoting Hu, Haihong Liu, Zhening Liu, Juan Du, Jingping Zhao, Lin Zhou, Kun Xia et al. · 2016 · Scientific Reports
- Targeting synaptic plasticity in schizophrenia: insights from genomic studiesArne W. Mould, Nicola Hall, Ira Milošević, Elizabeth M. Tunbridge · 2021 · Trends in Molecular Medicine
- Effects of the Glycine Transporter-1 Inhibitor Iclepertin (BI 425809) on Sensory Processing, Neural Network Function, and Cognition in Animal Models Related to SchizophreniaHolger Rosenbrock, Cornelia Dorner‐Ciossek, Riccardo Giovannini, Bernhard Schmid, Niklas Schuelert · 2022 · Journal of Pharmacology and Experimental Therapeutics
- Novel schizophrenia risk factor pathways regulate FEZ1 to advance oligodendroglia developmentXianjun Chen, Li Ku, Ruyi Mei, Guanglu Liu, Chongchong Xu, Zhexing Wen, Xiaofeng Zhao, Fei Wang, Lan Xiao, Yue Feng · 2017 · Translational Psychiatry
- Synapse pathology and translational applications for schizophreniaAkiko Hayashi‐Takagi · 2016 · Neuroscience Research
- Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and geneticsA. Schmitt, D. Rujescu, M. Gawlik, A. Hasan, K. Hashimoto, Sylvain Iceta, M. Jarema, J. Kambeitz, S. Kasper, D. Keeser et al. · 2016 · World Journal of Biological Psychiatry
- A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease riskJade Chapman, Elliott Rees, Denise H. Harold, Dobril K. Ivanov, Amy Gerrish, Rebecca Sims, Paul Hollingworth, Alexandra Stretton, Peter Holmans, Michael John Owen et al. · 2012 · Human Molecular Genetics
- The effect of ketamine on the consolidation and extinction of contextual fear memoryNicholas E. Clifton, Kerrie L. Thomas, Jérémy Hall · 2018 · Journal of Psychopharmacology
- Histone turnover and chromatin accessibility: Critical mediators of neurological development, plasticity, and diseaseWendy Wenderski, I. Maze · 2016 · Bioessays
- The Adenosine Neuromodulation System in SchizophreniaDaniel Rial, Diogo Rizzato Lara, Rodrigo Antunes Cunha · 2014 · International review of neurobiology
- Closing the translational gap between mutant mouse models and the clinical reality of psychotic illnessColm M. P. O’Tuathaigh, John L. Waddington · 2015 · Neuroscience & Biobehavioral Reviews
- What Next in Schizophrenia Genetics for the Psychiatric Genomics Consortium?Aiden Peter Corvin, Patrick F. Sullivan · 2016 · Schizophrenia Bulletin
- Interneuron NMDA Receptor Ablation Induces Hippocampus-Prefrontal Cortex Functional Hypoconnectivity after Adolescence in a Mouse Model of SchizophreniaRodrigo J. Alvarez, Diego E. Pafundo, Camila Lidia Zold, Juan Emilio Belforte · 2020 · Journal of Neuroscience
- Sarcosine as an add-on treatment to antipsychotic medication for people with schizophrenia: a systematic review and meta-analysis of randomized controlled trialsMattia Marchi, Giacomo Galli, Federica Maria Magarini, Giorgio Mattei, Gian Maria Galeazzi · 2021 · Expert Opinion on Drug Metabolism & Toxicology
- Implications of germline copy-number variations in psychiatric disorders: review of large-scale genetic studiesMasahiro Nakatochi, Itaru Kushima, Norio Ozaki · 2020 · Journal of Human Genetics
- Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia AetiologyDavid Curtis, Leda Coelewij, Shou-Hwa Liu, Jack Humphrey, Richard Mott · 2018 · Behavior Genetics
- Genetics of Childhood-onset Schizophrenia 2019 UpdateJennifer K. Forsyth, Robert F. Asarnow · 2019 · Child and Adolescent Psychiatric Clinics of North America
- The joint impact of cognitive performance in adolescence and familial cognitive aptitude on risk for major psychiatric disorders: a delineation of four potential pathways to illnessKenneth S. Kendler, Henrik Ohlsson, Richard S.E. Keefe, Kristina Sundquist, Jan Sundquist · 2017 · Molecular Psychiatry
- Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variantsBret Sanders, Daniel D’Andrea, Mark O. Collins, Elliott Rees, Tom G. J. Steward, Ying Zhu, Gareth Chapman, Sophie E. Legge, Antonio F. Pardiñas, Adrian J. Harwood et al. · 2022 · Nature Communications
- Differential expression of transcriptional regulatory units in the prefrontal cortex of patients with bipolar disorder: potential role of early growth response gene 3Bianca Pfaffenseller, Pedro Vieira da Silva Magalhães, Marco Antônio De Bastiani, Mauro A. A. Castro, Amelia L. Gallitano, Flávio Pereira Kapczinski, Fábio Klamt · 2016 · Translational Psychiatry
- Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic FunctionJinglan Yan, Youcan Pan, Xiaoyan Zheng, Chuanan Zhu, Yu Zhang, Guoqi Shi, Lin Yao, Yongjun Chen, Nenggui Xu · 2019 · Neuroscience Bulletin
- Paternal age and 13 psychiatric disorders in the offspring: a population-based cohort study of 7 million children in TaiwanShi‐Heng Wang, Chi‐Shin Wu, Le‐Yin Hsu, Mei‐Chen Lin, Pei‐Chun Chen, Wesley Kurt Thompson, Chun Chieh Fan · 2022 · Molecular Psychiatry
- Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophreniaFedor E. Gusev, Denis A. Reshetov, Amanda Mitchell, Т. В. Андреева, Aslihan Dincer, Anastasia P. Grigorenko, Gennady G. Fedonin, Tobias B. Halene, Maria Aliseychik, Elena Filippova et al. · 2019 · Translational Psychiatry
- Genetic association of FMRP targets with psychiatric disordersNicholas E. Clifton, Elliott Rees, Peter Holmans, Antonio F. Pardiñas, Janet C Harwood, Arianna Di Florio, George Kirov, James Walters, Michael C. O’Donovan, Michael John Owen et al. · 2020 · Molecular Psychiatry
- Reduced expression of the psychiatric risk gene DLG2 (PSD93) impairs hippocampal synaptic integration and plasticitySimonas Griesius, Cian O’Donnell, Sophie Waldron, Kerrie L. Thomas, Dominic Michael Dwyer, Lawrence S. Wilkinson, Jérémy Hall, Emma S. J. Robinson, Jack R. Mellor · 2022 · Neuropsychopharmacology
- Dysfunction of the NMDA Receptor in the Pathophysiology of Schizophrenia and/or the Pathomechanisms of Treatment-Resistant SchizophreniaRuri Okubo, Motohiro Okada, Eishi Motomura · 2024 · Biomolecules
- Abnormalities in Prefrontal Cortical Gene Expression Profiles Relevant to Schizophrenia in MK-801-Exposed C57BL/6 MiceJialu Zhao, Xu Liu, Chunyue Huo, Tian Zhao, Haihong Ye · 2018 · Neuroscience
- High Incidence of Copy Number Variants in Adults with Intellectual Disability and Co-morbid Psychiatric DisordersMarina Viñas‐Jornet, Susanna Esteba‐Castillo, Neus Baena, Núria Ribas‐Vidal, Anna Ruiz, David Torrents‐Rodas, Elisabeth Gabau, Elisabet Vilella, Lourdes Martorell, Lluı́s Armengol et al. · 2018 · Behavior Genetics
- ‘Arc’-hitecture of normal cognitive agingCraig Myrum, Perla Moreno‐Castilla, Peter R. Rapp · 2022 · Ageing Research Reviews
- Neural oscillations as a translational tool in schizophrenia research: Rationale, paradigms and challengesKeith Geoffrey Phillips, Peter J. Uhlhaas · 2015 · Journal of Psychopharmacology
- Genome-wide association analysis identifies common variants influencing infant brain volumesXia, K, Zhang, J, Ahn, M, Jha, S, Crowley, J J, Szatkiewicz, J, Li, T, Zou, F, Zhu, H, Hibar, D et al. · 2017 · Translational Psychiatry
- A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk scoreDavid Curtis · 2018 · European Journal of Human Genetics
- Risk genes for schizophrenia: Translational opportunities for drug discoveryCatherine L. Winchester, Judith A. Pratt, BRIAN J. MORRIS · 2014 · Pharmacology & Therapeutics
- CNest: A novel copy number association discovery method uncovers 862 new associations from 200,629 whole-exome sequence datasets in the UK BiobankTomas W. Fitzgerald, Ewan Birney · 2022 · Cell Genomics
- A comprehensive benchmarking of WGS-based deletion structural variant callersVaruni Sarwal, Sebastian Niehus, Ram Ayyala, Minyoung Kim, Aditya Prasad Sarkar, Sei Chang, Angela Lu, Neha Rajkumar, Nicholas Darci-Maher, Russell Littman et al. · 2022 · Briefings in Bioinformatics
- A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein AggregationLeslie G. Nucifora, YeeWen Candace Wu, Brian J. Lee, Li Sha, Russell L. Margolis, Christopher A. Ross, Akira Sawa, Frederick Charles Nucifora · 2016 · Complex Psychiatry
- Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia RiskMark Z. Kos, Melanie A. Carless, Juan M. Peralta, August N. Blackburn, Marcio Almeida, David R. Roalf, Michael F. Pogue‐Geile, Konasale M. R. Prasad, Ruben C. Gur, Vishwajit Laxmikant Nimgaonkar et al. · 2015 · Schizophrenia Bulletin
- Prenatal immune activation interacts with stress and corticosterone exposure later in life to modulate N-methyl-d-aspartate receptor synaptic function and plasticityMelissa A. Burt, Yiu Chung Tse, Patricia Boksa, Tak Pan Wong · 2013 · The International Journal of Neuropsychopharmacology
- FMRP and CYFIP1 at the Synapse and Their Role in Psychiatric VulnerabilityClifton, Nicholas E., Thomas, Kerrie L., Wilkinson, Lawrence S., Hall, Jeremy, Trent, Simon · 2020 · Complex Psychiatry
- Biological pathways and networks implicated in psychiatric disordersPatrick F. Sullivan, Daniëlle Posthuma · 2014 · Current Opinion in Behavioral Sciences
- Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genesMitra Etemadikhah, Adnan Niazi, Lennart Wetterberg, Lars Feuk · 2020 · Scientific Reports
- A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein FoldingPatrick R. Blackburn, Alexander Tischer, Michael T. Zimmermann, Jennifer L. Kemppainen, Sujatha Sastry, Amy E. Knight Johnson, Margot A. Cousin, Nicole J. Boczek, Gavin R. Oliver, Vinod K. Misra et al. · 2017 · Journal of Biological Chemistry
- Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neuronsZhang, Siwei, Zhang, Hanwen, Forrest, Marc P., Zhou, Yifan, Sun, Xiaotong, Bagchi, Vikram A., Kozlova, Alena, Santos, Marc Dos, Piguel, Nicolas H., Dionisio, Leonardo E. et al. · 2023 · Cell Genomics
- SAPAP Scaffold Proteins: From Synaptic Function to Neuropsychiatric DisordersYunxia Bai, Huimin Wang, Chunxia Li · 2022 · Cells
- Novel treatment strategies for schizophrenia from improved understanding of genetic riskBillah Morris, Judith A. Pratt · 2014 · Clinical Genetics